Curcumin induces apoptosis through FAS and FADD, in caspase-3-dependent and -independent pathways in the N18 mouse-rat hybrid retina ganglion cells

Oncology Reports

Volumn 22, Issue 1, 2009, Pages 97-104

  Lu, Hsu Feng ^a   Lai, Kuang Chi ^b,c   Hsu, Shu Chun ^d   Lin, Hui Ju ^b   Yang, Mei Due ^b   Chen, Yuan Liang ^e   Fan, Ming Jen ^f   Yang, Jai Sing ^d   Cheng, Pi Yun ^g   Kuo, Chao Lin ^d   Chung, Jing Gung ^d,f  

^a CHENG HSIN REHABILITATION MEDICAL CENTER   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e YUANPEI UNIVERSITY   (Taiwan)

^f ASIA UNIVERSITY   (Taiwan)

^g NATIONAL CHANGHUA UNIVERSITY OF EDUCATION   (Taiwan)

Author keywords

Apoptosis; Caspase; Cell cycle arrest; Curcumin; Mitochondria; Mouse rat hybrid retina ganglion N18 cells

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; APOPTOSIS INDUCING FACTOR; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CALCIUM ION; CASPASE 3; CASPASE 8; CASPASE 9; CURCUMIN; CYTOCHROME C; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TRYPAN BLUE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; DOWN REGULATION; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FLOW CYTOMETRY; HYBRID CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN SECRETION; RAT; RETINA GANGLION CELL; STAINING; TIME; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CALCIUM; CASPASE 3; CELL CYCLE; CELL LINE; CELL SURVIVAL; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HYBRID CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 68249148013     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000411     Document Type: Article

References (37)

1. Degterev A, Boyce M and Yuan J: A decade of caspases. Oncogene 22: 8543-8567, 2003.
2. Ziegler DS and Kung AL: Therapeutic targeting of apoptosis pathways in cancer. Curr Opin Oncol 20: 97-103, 2008.
3. Klein S, McCormick F and Levitzki A: Killing time for cancer cells. Nat Rey Cancer 5: 573-580, 2005.
4. O'Neill J, Manion M, Schwartz P, et al: Promises and challenges of targeting bcl-2 anti-apoptotic proteins for cancer therapy. Biochim Biophys Acta 1705: 43-51, 2004.
5. Debatin KM: Apoptosis pathways in cancer and cancer therapy. Cancer Immunol Immunother 53: 153-159, 2004.
6. Green DR: Apoptotic pathways: Ten minutes to dead. Cell 121: 671-674, 2005.
7. Sharma OP: Antioxidant activity of curcumin and related compounds. Biochem Pharmacol 25: 1811-1812, 1976.
8. Hanif R, Qiao L, Shiff SJ, et al: Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway. J Lab Clin Med 130: 576-584, 1997.
9. Rao CV, Rivenson A, Simi B, et al: Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res 55: 259-266, 1995.
10. Nagabhushan M and Bhide SV: Curcumin as an inhibitor of cancer. J Am Coll Nutr 11: 192-198, 1992.
11. Lu YP, Chang RL, Lou YR, et al: Effect of curcumin on 12-o-tetradecanoylphorbol-13-acetate- and ultraviolet b light-induced expression of c-jun and c-los in jb6 cells and in mouse epidermis. Carcinogenesis 15: 2363-2370, 1994.
12. Kakar SS and Roy D: Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger rRNA in mouse skin. Cancer Lett 87: 85-89, 1994.
13. Huang TS, Lee SC and Lin JK: Suppression of c-jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells. Proc Natl Acad Sci USA 88: 5292-5296, 1991.
14. Lloyd DR, Phillips DH and Carmichael PL: Generation of putative intrastrand cross-links and strand breaks in DNA by transition metal ion-mediated oxygen radical attack. Chem Res Toxicol 10: 393-400, 1997.
15. Xu J, Bubley GJ, Detrick B, et al: Chromium(vi) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle. Carcinogenesis 17:1511-1517, 1996.
16. Jana NR, Dikshit P, Goswami A, et al: Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. J Biol Chem 279:11680-11685, 2004.
17. Logan-Smith MJ, East JM and Lee AG: Evidence for a global inhibitor-induced conformation change on the Ca(2+)-ATPase of sarcoplasmic reticulum from paired inhibitor studies. Biochemistry 41: 2869-2875, 2002.
18. 2+. J Biol Chem 276: 46905-46911, 2001.
19. Pae HO, Jeong SO, Jeong GS, et al: Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells. Biochem Biophys Res Comm 353: 1040-1045, 20.
20. Bakhshi J, Weinstein L, Poksay KS, et al: Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: Effect of curcumin. Apoptosis 13: 904-914, 2008.
21. 2+ on the dads-induced apoptosis in mouse-rat hybrid retina ganglion cells (N18). Neurochem Res 31: 383-393, 2006.
22. 2+-dependent mitochondrial pathway. In Vivo 21: 1053-1058, 2007.
23. Lu HF, Chen YS, Yang JS, et al: Gypenosides induced G0/G1 arrest via inhibition of cyclin e and induction of apoptosis via activation of caspases-3 and -9 in human lung cancer A-549 cells. In Vivo 22: 215-221, 2008.
24. Wolf BB and Green DR: Suicidal tendencies: Apoptotic cell death by caspase family proteinases. J Biol Chem 274: 20049-20052, 1999.
25. Kaufmann SH, Desnoyers S, Ottaviano Y, et al: Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. Cancer Res 53: 376-3985, 1993.
26. Su CC, Yang JS, Lin SY, et al: Curcumin inhibits wehi-3 leukemia cells in BALB/c mice in vivo. In Vivo 22: 63-68, 2008.
27. Xu K and Thornalley PJ: Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro. Biochem Pharmacol 61: 165-177, 2001.
28. Ushida J, Sugie S, Kawabata K, et al: Chemopreventive effect of curcumin on N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats. Jpn J Cancer Res 91: 893-898, 2000.
29. Ihmels H, Faulhaber K, Vedaldi D, et al: Intercalation of organic dye molecules into double-stranded DNA. Part 2: The annelated quinolizinium ion as a structural motif in DNA intercalators. Photochem Photobiol 81: 1107-1115, 2005.
30. Li TK, Bathory E, LaVoie EJ, et al: Human topoisomerase I poisoning by protoberberines: Potential roles for both drug-DNA and drug-enzyme interactions. Biochemistry 39: 7107-7116, 2000.
31. Krey AK and Hahn FE: Berberine: complex with DNA. Science 166: 755-757, 1969.
32. Rashmi R, Kumar S and Karunagaran D: Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-xl. Carcinogenesis 26: 713-723, 2005.
33. + T lymphocytes. Toxicol Appl Pharmacol 193: 97-105, 2003.
34. Budihardjo I, Oliver H, Lutter M, et al: Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15: 269-290, 1999.
35. Ashkenazi A and Dixit VM: Death receptors: Signaling and modulation. Science 281: 1305-1308, 1998.
36. Wu Y, Zhang H, Dong Y, et al: Endoplasmic reticulum stress signal mediators are targets of selenium action. Cancer Res 65: 9073-9079, 2005.
37. Gomez-Santos C, Barrachina M, Gimenez-Xavier P, et al: Induction of c/ebp beta and gadd153 expression by dopamine in human neuroblastoma cells. Relationship with alpha-synuclein increase and cell damage. Brain Res Bull 65: 87-95, 2005.