Role of DNA polymerase beta in the genotoxicity of arsenic

Environmental and Molecular Mutagenesis

Volumn 52, Issue 6, 2011, Pages 460-468

  Lai, Yanhao ^a   Zhao, Wei ^a   Chen, Chen ^a   Wu, Mei ^a   Zhang, Zunzhen ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Arsenic; Base excision repair; DNA damage; DNA polymerase ; Genotoxicity

Indexed keywords

ARSENIC; ARSENIC TRIOXIDE; CELL DNA; DNA DIRECTED DNA POLYMERASE BETA;

CARCINOGENICITY; CHROMOSOME BREAKAGE; CYTOTOXICITY; DNA DAMAGE; ENZYME DEFICIENCY; EXCISION REPAIR; FIBROBLAST; GENE OVEREXPRESSION; GENOTOXICITY; MICRONUCLEUS; REVIEW; WILD TYPE;

ANIMALS; ARSENIC; CELLS, CULTURED; COMET ASSAY; DNA DAMAGE; DNA POLYMERASE BETA; DNA REPAIR; MICE; MICRONUCLEUS TESTS;

EID: 79959874900     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20643     Document Type: Review

References (52)

1. Andrew AS, Karagas MR, Hamilton JW. 2003. Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water. Int J Cancer 104: 263-268.
2. Andrew AS, Burgess JL, Meza MM, Demidenko E, Waugh MG, Hamilton JW, Karagas MR. 2006. Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. Environ Health Perspect 114: 1193-1198.
3. Barrett JC, Lamb PW, Wang TC, Lee TC. 1989. Mechanisms of arsenic induced cell transformation. Biol Trace Element Res 21: 421-429.
4. Bau DT, Wang TS, Chung CH, Wang AS, Jan KY. 2002. Oxidative DNA adducts and DNA-protein cross-links are the major DNA lesions induced by arsenite. Environ Health Perspect 110: 753-756.
5. Barzilai A, Yamamoto K. 2004. DNA damage responses to oxidative stress. DNA Repair (Amst) 3: 1109-1115.
6. Cebrian ME, Albores A, Aguilar M, Blakely E. 1983. Chronic arsenic poisoning in the north of Mexico. Hum Toxicol 2: 121-133.
7. Chapell WR, Beck BD, Brown KG, Chaney R, Cothern R, Irgolic KL, North DW, Thornton I, Tsongas TA. 1997. Inorganic arsenic: A need and an opportunity to improve risk assessment. Environ Health Perspect 105: 1060-1067.
8. Demple B, Harrison L. 1994. Repair of oxidative damage to DNA: Enzymology and biology. Annu Rev Biochem 63: 915-948.
9. Dong JT, Luo XM. 1993. Arsenic-induced DNA-strand breaks associated with DNA-protein crosslinks in human fetal lung fibroblasts. Mutat Res 302: 97-102.
10. Davis JS, Darcy CJ, Piera K, McNeil YR, Woodberry T, Anstey NM. 2009. Ex-vivo changes in amino acid concentrations from blood stored at room temperature or on ice: Implications for arginine and taurine measurements. BMC Clin Pathol 27: 9-10.
11. Frechet M, Canitrot Y, Cazaux C, Hoffmann JS. 2001. DNA polymerase beta imbalance increases apoptosis and mutagenesis induced by oxidative stress. FEBS Lett 505: 229-232.
12. Fenech M. 2000. The in vitro micronucleus technique. Mutat Res 455: 81-95.
13. Fenech M. 2002a. Chromosomal biomarkers of genomic instability relevant to cancer. Drug Discov Today 7: 1128-1137.
14. Fenech M. 2002b. Biomarkers of genetic damage for cancer epidemiology. Toxicology 181-182: 411-416.
15. Hartwig A, Groblinghoff UD, Beyersmann D, Nataranjan AT, Filon R, Mullenders LHF. 1997. Interaction of arsenic (III) with nucleotide excision repair in UV-irradiated human fibroblasts. Carcinogenesis 18: 399-405.
16. Helbig R, Speit G. 1997. DNA effects in repair-deficient V79 Chinese hamster cells studied with the comet assay. Mutat Res 377: 279-286.
17. Hu Y, Su L, Snow ET. 1998. Arsenic toxicity is enzyme specific and its affects on ligation are not caused by the direct inhibition on DNA repair enzymes. Mutat Res 408: 203-218.
18. Hughes MF. 2002. Arsenic toxicity and potential mechanisms of action. Toxicol Lett 133: 1-16.
19. Hei TK, Filipic M. 2004. Role of oxidative damage in the genotoxicity of arsenic. Free Radic Biol Med 37: 574-581.
20. Halliwell B. 2007. Oxidative stress and cancer: Have we moved forward? Biochem 401: 1-11.
21. IARC. 1980. Monographs on the evaluation of the carcinogenic risk of chemicals to man: Some metals and metallic compounds. Int Agency Res Cancer Lyon 23: 39-141.
22. IARC. 1987. Monographs on the evaluation of the carcinogenic risk to humans: Arsenic and arsenic compounds (Group 1). Int Agency Res Cancer Lyon Suppl 7: 100-103.
23. IARC. 2004. Some drinking water disinfectants and contaminants, including arsenic. IARC Monograph on the Evaluation of Carcinogenic Risks to Humans. Int Agency Res Cancer Lyon France 84: 209-214.
24. Kitchin KT. 2001. Recent advances in arsenic carcinogenesis: Modes of action, animal model systems, and methylated arsenic metabolites. Toxicol Appl Pharmacol 172: 249-261.
25. Kessel M, Liu SX, Xu A, Santella R, Hei TK. 2002. Arsenic induces oxidative DNA damage in mammalian cells. Mol Cell Biochem 234-235: 301-308.
26. Kitchin KT, Ahmad S. 2003. Oxidative stress as a possible mode of action for arsenic carcinogenesis. Toxicol Lett 137: 3-13.
27. Konca K, Lankoff A, Banasik A, Lisowska H, Kuszewski T, Gózdz S, Koza Z, Wojcik A. 2003. A cross-platform public domain PC image-analysis program for the comet assay. Mutat Res 534: 15-20.
28. Li JH, Rossman TG. 1989. Mechanism of comutagenesis of sodium arsenite with N-methyl-N-nitrosourea. Biol Trace Elem 21: 373-381.
29. Lee C, Wang MC, Yu CT, Wu DR, Jan KY. 1993. Nickel chloride inhibits the DNA repair of UV-treated but not methyl methanesulfonate-treated Chinese hamster ovary cells. Biol Trace Elem Res 37: 39-50.
30. Lee-Chen SF, Gurr JR, Lin IB, Jan KY. 1993. Arsenite enhances DNA double-strand breaks and cell killing of methyl methanesulfonate-treated cells by inhibiting the excision of alkali-labile sites. Mutat Res 294: 21-28.
31. Lynn S, Lai HT, Gurr JR, Jan KY. 1997. Arsenite retards DNA break rejoining by inhibiting DNA ligation. Mutagen 12: 353-358.
32. Liu F, Jan KY. 2000. DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells. Free Radic Biol Med 28: 55-63.
33. Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
34. Mourón SA, Grillo CA, Dulout FN, Golijow CD. 2006. Induction of DNA strand breaks, DNA-protein crosslinks and sister chromatid exchanges by arsenite in a human lung cell line. Toxicol In Vitro 20: 279-285.
35. Olive PL, Banáth JP, Durand RE. 1990. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay. Radiat Res 122: 86-94.
36. Olive PL, Banáth JP. 1995. Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp Cell Res 22: 19-26.
37. Ruiz-Ramos R, Lopez-Carrillo L, Rios-Perez AD, Vizcaya-Ruíz AD, Cebrian ME. 2009. Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NF-κB activation and cell proliferation in human breast cancer MCF-7 cells. Mutat Res/Genetic Toxicol Environ Mutat 674: 109-115.
38. Samson LD. 1992. The repair of DNA alkylation damage by methyltransferases and glycosylases. Essays Biochem 27: 69-78.
39. Sobol RW, Prasad R, Evenski A, Baker A, Yang XP, Horton JK, Wilson SH. 2000. The lyase activity of the DNA repair protein β-polymerase protects from DNA-damage-induced cytotoxicity. Nature 405: 807-810.
40. Schwerdtle T, Walter I, Hartwig A. 2003. Arsenite and its biomethylated metabolites interfere with the formation and repair of stable BPDE-induced DNA adducts in human cells and impair XPAzf and Fpg. DNA Repair 2: 1449-1463.
41. Shi H, Shi X, Liu KJ. 2004. Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol Cell Biochem 255: 67-78.
42. Sykora P, Snow ET. 2008. Modulation of DNA polymerase beta dependent base excision repair in cultured human cells after low dose exposure to arsenite. Toxicol Appl Pharmacol 228: 385-394.
43. Tseng WP. 1977. Effects and dose-response relationships of skin cancer and blackfoot disease with arsenic. Environ Health Perspect 19: 109-119.
44. Tolbert PE, Shy CM, Allen JW. 1992. Micronuclei and other nuclear anomalies in buccal smears: Methods development. Mutat Res 271: 69-77.
45. Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. 2006. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 160: 1-40.
46. Wallace SS. 1988. AP endonucleases and DNA glycosylases that recognize oxidative DNA damage. Environ Mol Mutagen 12: 431-477.
47. Wang TC. 1994. Delay of the excision of UV light-induced DNA adducts is involved in the coclastogenicity of UV light plus arsenite. Int J Rad Biol 66: 367-372.
48. Wang TS, Hsu TY, Chung CH, Wang AS, Bau DT, Jan KY. 2001. Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells. Free Radic Biol Med 31: 321-330.
49. WHO. 2001. Arsenic and Arsenic Compound, Environmental Health Criteria. Geneva: World Health Organization. p 224.
50. Wu M, Zhang ZZ, Che WJ. 2008. Suppression of a DNA base excision repair gene, hOGG1, increases bleomycin sensitivity of human lung cancer cell line. Toxicol Appl Pharmacol 228: 395-402.
51. Yager JW, Wiencke JK. 1997. Inhibition of poly(ADP-ribose) polymerase by arsenite. Mutat Res 386: 345-351.
52. Yoshida T, Yamauchi H, Sun GF. 2004. Chronic health effects in people exposed to arsenic via the drinking water: Dose-response relationships in review. Toxicol Appl Pharmacol 198: 243-252.