The role of CREB as a proto-oncogene in hematopoiesis

Cell Cycle

Volumn 4, Issue 9, 2005, Pages 1134-1135

  Kinjo, Kentaro ^a   Sandoval, Salemiz ^a   Sakamoto, Kathleen M ^a,b,c,d   Shankar, Deepa B ^a,b  

^a MATTEL CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Acute myeloid leukemia; CREB; Hematopoiesis; Proto oncogene; Transcription factor

Indexed keywords

BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; BLAST TRANSFORMATION; BONE MARROW CELL; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; GENE OVEREXPRESSION; HEMATOPOIESIS; HUMAN; LEUKEMIA CELL LINE; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; PHENOTYPE; PROTO ONCOGENE; SHORT SURVEY; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 25444435349     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.4.9.1991     Document Type: Short Survey

References (18)

1. Gonzalez GA, Montminy MR. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 1989;59(4):675-80.
2. Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy, M. TORCs: transducers of regulated CREB activity. Mol Cell 2003;12(2):413-23.
3. Mayr B, Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2001;2(8):599-609.
4. Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, Best J, Chen, H. Jenner, R. Herbolsheimer, E. Jacobsen, E. Kadam, S. Ecker, J. R. Emerson, B. Hogenesch, J. B. Unterman, T. Young, R. A. Montminy, M. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci U S A 2005;102(12):4459-64.
5. Zucman J, Delattre O, Desmaze C, Epstein AL, Stenman G, Speleman F, Fletchers, C. D. Aurias, A. Thomas, G. EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts. Nat Genet 1993;4(4):341-5.
6. Kuo CT, Leiden JM. Transcriptional regulation of T lymphocyte development and function. Annu Rev Immunol 1999;17:149-87.
7. Arcinas M, Heckman CA, Mehew JW, Boxer LM. Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma. Cancer Res 2001;61(13):5202-6.
8. Ji L, Mochon E, Arcinas M, Boxer LM. CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas. J Biol Chem 1996;271(37):22687-91.
9. Sunaga S MK, Lagasse E, Blanco JC, Ozato K, Miyazaki J, K Ikuta. Myeloid differentiation is impaired in transgenic mice with targeted expression of a dominant negative form of reinoid X receptor beta. British Journal of Hematology 1997;96:19-30.
10. Oike Y, Takakura N, Hata A, Kaname T, Akizuki M, Yamaguchi Y, H YasueK ArakiK YamamuraT Suda. Mice homozygous for a truncated form of CREB-Binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis. Blood 1999;93:2771-79.
11. Lee HJ, Mignacca RC, Sakamoto KM. Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133. J Biol Chem 1995;270(27):15979-83.
12. Crans-Vargas H, Landaw E, Bhatia S, Sandusky G, Sakamoto K. CREB Expression in acute leukemias. Blood 2002;99:2017-19.
13. Shankar D, Sakamoto KM. The Role of Cyclin-AMP Response Element Binding Protein in Leukemia Cell Proliferation and Acute Leukemias. Leukemia and Lymphoma 2004;45(2):265-70.
14. Shankar DB, Cheng J, Kinjo K, Fedreman N, Moore TB, Gill A, Rao, NP, Landaw, EM, Sakamoto, K. M.. The Role of CREB as a Proto-Oncogene in Hematopoiesis and in Acute Myeloid Leukemia. Cancer Cell 2005;7.
15. Yuan Y, Zhou L, Miyamoto T, Iwasaki H, Harakawa N, Hetherington CJ, Burel, S. A. Lagasse, E. Weissman, I. L. Akashi, K.Zhang, D. E. AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations. Proc Natl Acad Sci U S A 2001;98(18):10398-403.
16. Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau, M.M. Shannon, K.M. Somatic Activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder. Proc Natl Acad Sci U S A 2004;101(2):597-602.
17. Chan I, Kutok JL, Williams IR, Cohen S, Kelly LM, Shigematsu H, Johnson, L. Akashi, K. Tuveson, D.A. Jacks, T. Gilliland, D. G. Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloprroliferative disease. J. Clin. Invest. 2004;113:528-38.
18. Stone RM, O'Donnell MR, Sekeres MA. Acute myeloid leukemia. Hematology (Am Soc Hematol Educ Program) 2004:98-117.