Glycosylation affects ligand binding and function of the activating natural killer cell receptor 2B4 (CD244) protein

Journal of Biological Chemistry

Volumn 286, Issue 27, 2011, Pages 24142-24149

  Margraf Schönfeld, Stefanie ^a   Böhm, Carolin ^a   Watzl, Carsten ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DESIALYLATION; EXTRACELLULAR DOMAINS; FUNCTIONAL ASSAYS; FUSION PROTEINS; GLYCOSYLATED; LIGAND BINDING; N-LINKED GLYCOSYLATION; NATURAL KILLER CELLS; NEGATIVE IMPACTS; NK CELLS; O-LINKED; SIALIC ACIDS; SIALYLATION; TARGET CELLS;

CARBOHYDRATES; CARBOXYLIC ACIDS; CELL CULTURE; CELL MEMBRANES; CHEMICAL ACTIVATION; ESTERIFICATION; LIGANDS;

GLYCOSYLATION;

CD48 ANTIGEN; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR 2B4; RECOMBINANT PROTEIN; SIALIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; LIGAND BINDING; LYMPHOCYTE FUNCTION; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION; SIALYLATION; TARGET CELL; TUMOR CELL DESTRUCTION;

ANTIGENS, CD; GLYCOSYLATION; HEK293 CELLS; HELA CELLS; HUMANS; KILLER CELLS, NATURAL; LIGANDS; LYMPHOCYTE ACTIVATION; RECEPTORS, IMMUNOLOGIC;

EID: 79959862691     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.225334     Document Type: Article

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