Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells

Human Molecular Genetics

Volumn 14, Issue 23, 2005, Pages 3661-3671

  Arocena, Dolores Garcia ^a,b   Iwahashi, Christine K ^a   Won, Nelly ^a   Beilina, Alexandra ^a   Ludwig, Anna L ^a   Tassone, Flora ^a   Schwartz, Philip H ^c   Hagerman, Paul J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^c Children's Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; FRAGILE X MENTAL RETARDATION PROTEIN; LAMIN A; LAMIN C; MESSENGER RNA; PROTEASOME; UBIQUITIN;

5' UNTRANSLATED REGION; ALLELE; ARTICLE; CELL CULTURE; CELL NUCLEUS; CELL NUCLEUS INCLUSION BODY; CONTROLLED STUDY; DEGENERATIVE DISEASE; FRAGILE X ASSOCIATED TREMOR ATAXIA SYNDROME; FRAGILE X SYNDROME; GENE MUTATION; HEREDITARY MOTOR SENSORY NEUROPATHY; HETEROZYGOTE; HUMAN; HUMAN CELL; NERVE CELL; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN STRUCTURE; TRINUCLEOTIDE REPEAT; UBIQUITINATION;

5' UNTRANSLATED REGIONS; ALPHA-CRYSTALLIN B CHAIN; APOPTOSIS; CELL NUCLEUS; CELLS, CULTURED; CYTOSINE; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; GUANOSINE; HUMANS; INTERMEDIATE FILAMENT PROTEINS; INTRANUCLEAR INCLUSION BODIES; LAMIN TYPE A; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PROTEIN KINASES; STEM CELLS; TRANSFECTION; TRINUCLEOTIDE REPEAT EXPANSION; UBIQUITIN;

ATAXIA;

EID: 28744442194     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi394     Document Type: Article

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