Productive parvovirus B19 infection of primary human erythroid progenitor cells at hypoxia is regulated by STAT5A and MEK signaling but not HIFα

PLoS Pathogens

Volumn 7, Issue 6, 2011, Pages

  Chen, Aaron Yun ^a   Kleiboeker, Steve ^b   Qiu, Jianming ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b Viracor IBT Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; STAT5A PROTEIN; CD36 ANTIGEN; HIF1A PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; STAT5 PROTEIN; STAT5A PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL CULTURE; ERYTHROID PRECURSOR CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN PARVOVIRUS B19; HYPOXIA; PARVOVIRUS; PARVOVIRUS INFECTION; PATHOGENESIS; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; VIRUS GENOME; VIRUS REPLICATION; ANOXIA; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA REPLICATION; ERYTHEMA INFECTIOSUM; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; VIROLOGY;

PARVOVIRUS;

ANOXIA; ANTIGENS, CD36; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DNA REPLICATION; ERYTHEMA INFECTIOSUM; ERYTHROID PRECURSOR CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; PARVOVIRUS B19, HUMAN; STAT5 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEINS; VIRUS REPLICATION;

EID: 79959817022     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002088     Document Type: Article

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