Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation

Blood

Volumn 92, Issue 6, 1998, Pages 1859-1869

  Nagata, Yuka ^b   Takahashi, Noriko ^b   Davis, Roger J ^b   Todokoro, Kazuo ^a  

^a RIKEN TSUKUBA INSTITUTE   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTISENSE OLIGONUCLEOTIDE; ERYTHROPOIETIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ERYTHROID CELL; ERYTHROLEUKEMIA CELL; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032530921     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.6.1859     Document Type: Article

References (65)

1. Neiman AM: Conservation and reiteration of a kinase cascade. Trends Genet 9:390, 1993
2. Nishida E, Gotoh Y: The MAP kinase cascade is essential for diverse signal transduction pathway. Trends Biochem Sci 18:128, 1993
3. Boulton TG, Nye SH, Robbins DJ, Ip NY, Radziejewska E, Morgenbesser SD, DePinho RA, Panayotatos N, Cobb MH, Yancopoulos GD: ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65:663, 1991
4. Seger R, Ahn NG, Boulton TG, Yancopoulos GD, Panayotatos N, Radziejewska E, Ericsson L, Bratlien RL, Cobb MH, Krebs EG: Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: Implications for their mechanism of activation. Proc Natl Acad Sci USA 88:6142, 1991
5. Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR: The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369:156, 1994
6. Derijard B, Hibi M, Wu I-H, Barrett T, Su B, Deng T, Karin M, Davis, R J: JNK1: A protein kinase stimulated by UV light and H-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025, 1994
7. Han J, Lee JD, Bibbs L, Ulevitch RJ: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808, 1994
8. Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR: A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78:1027, 1994
9. Lee JD, Ulevitch RJ, Han J: Primary structure of BMK1 : A new mammalian MAP kinase. Biochem Biophys Res Commun 213:715, 1995
10. Zhou G, Bao ZQ, Dixon JE: Components of a new human protein kinase signal transduction pathway. J Biol Chem 270:12665, 1995
11. Ray LB, Sturgill TW: Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubuleassociated protein 2 in vitro. Proc Natl Acad Sci USA 84:1502, 1987
12. Marshall CJ: Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179, 1995
13. Pages G, Lenormand P, L' Allemain G, Chambard JC, Meloche S, Poyssegur J: Mitogen-activated protein kinase p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sci USA 90:8319, 1993
14. Van M, Dai T, Deak JC, Kyriakis JM, Zon LI, Woodgett JR, Templeton DJ: Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activation SEK1. Nature 372:798, 1994
15. Raingeaud J, Gupta S, Rogers J, Dickens M, Han J, Ulevitch R, Davis, RJ: Pro-inflammatory cytokines and environmental stress cause p38 MAP kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270:7420, 1995
16. Freshney NW, Rawlinson L, Guesdon F, Jones E, Cowley S, Hsuan J, Saklatvala J: Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27. Cell 78:1039, 1994
17. Galcheva-Gargova Z, Derijard B, Wu IH, Davis RJ: An osmosensing signal transduction pathway in mammalian cells. Science 265:806, 1994
18. Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW, Strickler JE, McLaughlin MM, Siemens IR, Fisher SM, Livi GP, White JR, Adams JL, Young PR: A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739, 1994
19. Sluss HK, Barren T, Derijard B, Davis RJ: Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol 14:8376, 1994
20. Westwick JK, Bielawska AE, Dbaibo G, Hannun YA, Brenner DA: Ceramide activates the stress-activated protein kinases. J Biol Chem 270:22689, 1995
21. Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S, Birrer MJ, Szabo E, Zon LI, Kyriakis JM, Haimovitz-Friedman A, Fuks Z, Kolesnick RN: Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature 380:75, 1996
22. Lenczowski JM, Dominguez L, Eder AM, King LB, Zacharchuk CM, Ashwell JD: Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis. Mol Cell Biol 17:170, 1996
23. Berberich I, Shu G, Siebelt F, Woodgett JR, Kyriakis JM, Clark EA: Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases. EMBO J 15:92, 1996
24. Liu ZG, Hsu H, Goeddel DV, Karin M: Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 87:565, 1996
25. Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y: JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727, 1994
26. Satoh T, Nakafuku M, MiyajimaA, Kaziro Y: Involvement of ras p21 protein in signal transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4. Proc Natl Acad Sci USA 88:3314, 1991
27. Satoh T, Nakafuku M, Kaziro Y: Function of Ras as a molecular switch in signal transduction. J Biol Chem 267:24149, 1992
28. Torti M, Marti KB, Altschuler D, Yamamoto K, Lapetina EG: Erythropoietin induces p21 ras activation and p120GAP tyrosine phosphorylation in human ery thro leukemia cells. J Biol Chem 267:8293, 1992
29. Sato N, Sakamaki K, Terada N, Arai K, Miyajima A: Signal transduction by the high-affinity GM-CSF receptor: Two distinct cytoplasmic regions of the common beta subunit responsible for different signal. EMBO J 12:4181, 1993
30. Todokoro K, Sugiyama M, Nishida E, Nakaya K: Activation of mitogen-activated protein kinase cascade through erythropoietin receptor. Biochem Biophys Res Commun 203:1912, 1994
31. Nagata Y, Todokoro K: Thrombopoietin induces activation of at least two distinct signaling pathways. FEBS Lett 377:497, 1995
32. Rausch O, Marshall CJ: Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathway. Mol Cell Biol 17:1170, 1997
33. Nagata Y, Nishida E, Todokoro K: Activation of JNK signaling pathway by erythropoietin, thrombopoietin, and interleukin-3. Blood 89:2664, 1997
34. Nagata Y, Moriguchi T, Nishida E, Todokoro K: Activation of p38 MAP kinase pathway by erythropoietin and interleukin-3. Blood 90:929, 1997
35. Foltz IN, Schrader JW: Activation of the stress-activated protein kinases by multiple hematopoietic growth factors with the exception of interleukin-4. Blood 89:3092, 1997
36. Foltz IN, Lee JC, Young PR, Schrader JW: Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway. J Biol Chem 272:3296, 1997
37. Todokoro K, Kanazawa S, Amanuma H, Ikawa Y: Specific binding of erythropoietin to its receptor on responsive mouse erythroleukemia cells. Proc Natl Acad Sci USA 84:4126, 1987
38. Worthington RE, Bossiecodreanu J, Vanzany G: Quantitation in vitro using a sensitive colorimetric assay for hemoglobin. Exp Hematol 15:85, 1987
39. Sale EM, Atkinson PG, Sale GJ: Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DMA synthesis. EMBO J 14:674, 1995
40. Hibi M, Lin A, Smeal T, Minden A, Karin M: Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 7:2135, 1993
41. Mossmann T: Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55, 1983
42. Sellins KS, Cohen JJ: Gene induction by γ-irradiation leads to DNA. fragmentation in lymphocytes. J Immunol 139:3199, 1987
43. Zechner D, Thuerauf DJ, Hanford DS, McDonough PM, Glembotski CC: A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression, J Cell Biol 139:115, 1997
44. Cowley S, Paterson H, Kemp P, Marshall CJ: Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841, 1994
45. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG: Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265:966, 1994
46. Font de Mora J, Porras A, Ahn N, Santos E: Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation. Mol Cell Biol 17:6068, 1997
47. Alberola-Ila J, Forbush KA, Seger R, Krebs EG, Perlmutter RM: Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373:620, 1995
48. Crompton T, Gilmour KC, Owen MJ: The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86:243, 1996
49. Melemed AS, Ryder JW, Vik TA: Activation of the mitogen-activated protein kinase pathway is involved in and sufficient for megakaryocytic differentiation of CMK cells. Blood 90:3462, 1997
50. Rouyez MC, Boucheron C, Gisselbrecht S, Dusanter-Fourt I, Porteu F: Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway. Mol Cell Biol 17:4991, 1997
51. Whalen AM, Galasinski SC, Shapiro PS, Nahreini TS, Ahn NG: Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol Cell Biol 17:1945, 1997
52. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326, 1995
53. Ichijo H, Nishida E, Irie K, Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y: Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275:90, 1997
54. Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL: Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. J Biol Chem 271:3229, 1996
55. Williams GT, Smith CA, Spooncer E, Dexter TM, Taylor DR: Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 343:76, 1990
56. Nishina H, Fischer KD, Radvanyi L, Shahinian A, Hakem R, Rubie EA, Bernstein A, Mak TW, Woodgett JR, Penninger JM: Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature 385:350, 1997
57. Crawley JB, Rawlinson L, Lali FV, Page TH, Saklatvala J, Foxwell BM: T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation. J Biol Chem 272:15023, 1997
58. Heasley LE, Storey B, Fanger GR, Butterfield L, Zamarripa J, Blumberg D, Maue RA: GTPase-deficient G alpha 16 and G alpha q induce PC 12 cell differentiation and persistent activation of cJun NH2-terminal kinases. Mol Cell Biol 16:648, 1996
59. de Groot RP, Kruyt FA, van der Saag PT, Kruijer W: Ectopic expression of c-jun leads to differentiation of P19 embryonal carcinoma cells. EMBO J 9:1831, 1990
60. Jho EH, Davis RJ, Malbon CC: c-Jun amino-terminal kinase is regulated by Galpha12/Galpha13 and obligate for differentiation of P19 embryonal carcinoma cells by retinoic acid. J Biol Chem 272:24468, 1997
61. + myelomonocytic leukemia cells induced by ectopic expression of the protooncogene c-jun. Cell Growth Differ 5:743, 1994
62. Minowada G, Welch W: Variation in the expression and/or phosphorylation of the human low molecular weight stress protein during in vitro cell differentiation. J Biol Chem 270:7047, 1995
63. Wang XZ, Ron D: Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 272:1347, 1996
64. Kyriakis JM, Avruch J: Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays 18:567, 1996
65. Kyriakis JM, Avruch J: Sounding the alarm: Protein kinase cascades activated by stress and inflammation. J Biol Chem 271:24313, 1996