α1A-Adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Wenzel, Katrin ^a,b   Wallukat, Gerd ^b   Qadri, Fatimunnisa ^a   Hubner, Norbert ^b   Schulz, Herbert ^b   Hummel, Oliver ^b   Herse, Florian ^a   Heuser, Arnd ^b   Fischer, Robert ^a,b   Heidecke, Harald ^c   Luft, Friedrich C ^b,d   Muller, Dominik N ^b   Dietz, Rainer ^a   Dechend, Ralf ^b,d  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c CellTrend   (Germany)

^d FRANZ VOLHARD CLINIC   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1A ADRENERGIC RECEPTOR; ANGIOTENSIN II; COLLAGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ADRENERGIC RECEPTOR ALPHA(1A); ALPHA 1 ADRENERGIC RECEPTOR; AUTOANTIBODY; IMMUNOGLOBULIN G;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ECHOCARDIOGRAPHY; ENERGY METABOLISM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETIC CODE; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE FIBROSIS; HEART RATE; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HEMODYNAMICS; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; LEWIS RAT; MALE; MUSCLE HYPERTROPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN PHOSPHORYLATION; RAT; SARCOMERE; SMOOTH MUSCLE FIBER; SYSTOLE; TELEMETRY; UPREGULATION; AMINO ACID SEQUENCE; ANIMAL; BLOOD PRESSURE; CHO CELL; CRICETULUS; CYTOLOGY; DIASTOLE; DRUG EFFECT; ELECTROCARDIOGRAPHY; GENE EXPRESSION PROFILING; HAMSTER; HEART; HEART MUSCLE; HEART MUSCLE CELL; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CRICETULUS GRISEUS; RATTUS;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; AUTOANTIBODIES; AUTOIMMUNITY; BLOOD PRESSURE; CHO CELLS; CRICETINAE; CRICETULUS; DIASTOLE; ELECTROCARDIOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; HEART; HUMANS; IMMUNOGLOBULIN G; MALE; MOLECULAR SEQUENCE DATA; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, INBRED LEW; RECEPTORS, ADRENERGIC, ALPHA-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77949701312     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009409     Document Type: Article

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