Pioglitazone reduces secondary brain damage after experimental brain trauma by PPAR-γ-independent mechanisms

Journal of Neurotrauma

Volumn 28, Issue 6, 2011, Pages 983-993

  Thal, Serge C ^a   Heinemann, Marius ^a   Luh, Clara ^a   Pieter, Dana ^a   Werner, Christian ^a   Engelhard, Kristin ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

inflammation; peroxisome proliferator activated receptor ; pioglitazone; rosiglitazone; traumatic brain injury

Indexed keywords

2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; AMINOPEPTIDASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPROTEIN LIPASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; ROSIGLITAZONE; SODIUM GLUCOSE COTRANSPORTER 1; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CONTUSION; BRAIN DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE MARKER; DRUG EFFECT; DRUG POTENTIATION; ENCEPHALITIS; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; MALE; MARKER GENE; MOUSE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; RECEPTOR UPREGULATION; TISSUE INJURY; TRAUMATIC BRAIN INJURY; WEIGHT REDUCTION;

ANIMALS; BRAIN DAMAGE, CHRONIC; BRAIN INJURIES; DISEASE MODELS, ANIMAL; HYPOGLYCEMIC AGENTS; MALE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; PPAR GAMMA; THIAZOLIDINEDIONES;

EID: 79959747617     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2010.1685     Document Type: Article

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