Polymorphic variants in tenascin-C (TNC) are associated with atherosclerosis and coronary artery disease

Human Genetics

Volumn 129, Issue 6, 2011, Pages 641-654

  Minear, Mollie A ^a   Crosslin, David R ^c   Sutton, Beth S ^d   Connelly, Jessica J ^e   Nelson, Sarah C ^c   Gadson Watson, Shera ^a   Wang, Tianyuan ^b   Seo, David ^f   Vance, Jeffrey M ^f   Sketch Jr , Michael H ^a   Haynes, Carol ^a   Goldschmidt Clermont, Pascal J ^f   Shah, Svati H ^a   Kraus, William E ^a   Hauser, Elizabeth R ^a   Gregory, Simon G ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d CAMPBELL UNIVERSITY   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TENASCIN;

ADULT; AORTA; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; POLYMORPHIC LOCUS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; FEMALE; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; TENASCIN;

EID: 79959737268     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-011-0959-z     Document Type: Article

References (67)

1. GR Abecasis WO Cookson 2000 GOLD-graphical overview of linkage disequilibrium Bioinformatics 16 182 183 10842743 10.1093/bioinformatics/16.2. 182 1:CAS:528:DC%2BD3cXktVyitrY%3D
2. JC Barrett B Fry J Maller MJ Daly 2005 Haploview: analysis and visualization of LD and haplotype maps Bioinformatics 21 263 265 15297300 10.1093/bioinformatics/bth457 1:CAS:528:DC%2BD2MXkt1WitQ%3D%3D (Pubitemid 40202029)
3. R Chapados K Abe K Ihida-Stansbury D McKean AT Gates M Kern S Merklinger J Elliott A Plant H Shimokawa PL Jones 2006 ROCK controls matrix synthesis in vascular smooth muscle cells: coupling vasoconstriction to vascular remodeling Circ Res 99 837 844 16990566 10.1161/01.RES.0000246172.77441.f1 1:CAS:528:DC%2BD28XhtVKjtL%2FK (Pubitemid 44556382)
4. RH Chung ER Hauser ER Marin 2007 Interpretation of simultaneous linkage and family-based association tests in genome screens Genet Epidemiol 31 134 142 17123303 10.1002/gepi.20196 (Pubitemid 46147662)
5. JJ Connelly T Wang JE Cox C Haynes L Wang SH Shah DR Crosslin AB Hale S Nelson DC Crossman CB Granger JL Haines CJH Jones JM Vance PJ Goldschmidt-Clermont WE Kraus ER Hauser SG Gregory 2006 GATA2 is associated with familial early-onset coronary artery disease PLoS Genet 2 e139 16934006 10.1371/journal.pgen.0020139 (Pubitemid 44298499)
6. JJ Connelly SH Shah JF Doss S Gadson S Nelson DR Crosslin AB Hale X Lou T Want C Haynes D Seo DC Crossman V Mooser CB Granger CJH Jones WE Kraus ER Hauser SG Gregory 2008 Genetic and functional association of FAM5C with myocardial infarction BMC Med Genet 9 33 18430236 10.1186/1471-2350-9-33 (Pubitemid 351709349)
7. JF Cornhill WA Barrett EE Herderick RW Mahley DL Fry 1985 Topographic study of sudanophilic lesions in cholesterol-fed minipigs by image analysis Arteriosclerosis 5 415 426 2412537 1:STN:280:DyaL2Mzgs1CqsQ%3D%3D (Pubitemid 15231295)
8. PIW de Bakker R Yelensky I Pe'er SB Gabriel MJ Daly D Altshuler 2005 Efficiency and power in genetic association studies Nat Genet 37 1217 1223 16244653 10.1038/ng1669 (Pubitemid 41568704)
9. AC Doran N Meller CA McNamara 2008 Role of smooth muscle cells in the initiation and early progression of atherosclerosis Arterioscler Thromb Vasc Biol 25 812 819 10.1161/ATVBAHA.107.159327 (Pubitemid 351544093)
10. M Fischer U Broeckel S Holmer A Baessler C Hengstenberg B Mayer J Erdmann G Klein G Riegger HJ Jacob H Schunkert 2005 Distinct heritable patterns of angiographic coronary artery disease in families with myocardial infarction Circulation 111 855 862 15710764 10.1161/01.CIR.0000155611.41961.BB (Pubitemid 40279886)
11. K Fujinaga K Onoda K Yamamoto K Imanaka-Yoshida M Takao T Shimono H Shimpo T Yoshida I Yada 2004 Locally applied cilostazol suppresses neointimal hyperplasia by inhibiting tenascin-C synthesis and smooth muscle cell proliferation in free artery grafts J Thorac Cardiovasc Surg 128 357 363 15354092 10.1016/j.jtcvs.2003.11.015 1:CAS:528:DC%2BD2cXosFyksbY%3D (Pubitemid 39194689)
12. MA Hauser Y-J Li S Takeuchi R Walters M Noureddine M Maready T Darden C Hulette E Martin E Hauser H Xu D Schmechel JE Stenger F Dietrich J Vance 2003 Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage Hum Mol Genet 12 671 677 12620972 10.1093/hmg/12.6.671 1:CAS:528:DC%2BD3sXjt1Slsbo%3D (Pubitemid 36372493)
13. ER Hauser V Mooser DC Crossman JL Haines CH Jones BR Winkelmann S Schmidt WK Scott AD Roses MA Pericak-Vance CB Granger WE Kraus 2003 Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study Am Heart J 145 602 613 12679755 10.1067/mhj.2003.13 (Pubitemid 36403488)
14. ER Hauser DC Crossman CB Granger JL Haines CJ Jones V Mooser B McAdam BR Winkelmann AH Wiseman JB Muhlestein AG Bartel CA Dennis E Dowdy S Estabrooks K Eggleston S Francis K Roche PW Clevenger L Huang B Pedersen S Shah S Schmidt C Haynes S West D Asper M Booze S Sharma S Sundseth L Middleton AD Roses MA Hauser JM Vance MA Pericak-Vance WE Kraus 2004 A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study Am J Hum Genet 75 436 447 15272420 10.1086/423900 1:CAS:528:DC%2BD2cXnt1Wgt7Y%3D (Pubitemid 39095819)
15. U Hedin J Holm GK Hansson 1991 Induction of tenascin in rat arterial injury: relationship to altered smooth muscle cell phenotype Am J Pathol 139 649 656 1716048 1:CAS:528:DyaK38XksFWh
16. A Helgadottir G Thorleifsson A Manolescu S Gretarsdottir T Blondal A Jonasdottir A Jonasdottir A Sigurdsson A Baker A Palsson G Masson DF Gudbjartsson KP Magnusson K Andersen AI Levey VM Backman S Matthiasdottir T Jonsdottir S Palsson H Einarsdottir S Gunnarsdottir A Gylfason V Vaccarino WC Hooper MP Reilly CB Granger H Austin DJ Rader SH Shah AA Quyyumi JR Gulcher G Thorgeirsson U Thorsteinsdottir A Kong K Stefansson 2007 A common variant on chromosome 9p21 affects the risk of myocardial infarction Science 316 1491 1493 17478679 10.1126/science.1142842 1:CAS:528:DC%2BD2sXmtFSjtro%3D (Pubitemid 46906618)
17. D Ilić Y Furuta S Kanazawa N Takeda K Sobue N Nakatsuji S Nomura J Fujimoto M Okada T Yamamoto 1995 Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice Nature 377 539 544 7566154 10.1038/377539a0
18. K Imanaka-Yoshida M Hiroe T Nishikawa S Ishiyama T Shimojo Y Ohta T Sakakura T Yoshida 2001 Tenascin-C modulates adhesion of cardiomyocytes to extracellular matrix during tissue remodeling after myocardial infarction Lab Invest 81 1015 1024 11454990 1:STN:280:DC%2BD3Mvgtlygsg%3D%3D (Pubitemid 32645977)
19. K Imanaka-Yoshida R Matsuura N Isaka T Nakano T Sakakura T Yoshida 2001 Serial extracellular matrix changes in neointimal lesions of human coronary artery after percutaneous transluminal coronary angioplasty: clinical significance of early tenascin-C expression Virchows Arch 439 185 190 11561759 10.1007/s004280000390 1:CAS:528:DC%2BD3MXlvFWqsbc%3D (Pubitemid 32758912)
20. FS Jones PL Jones 2000 The tenascin family of ECM glycoproteins: structure, function, and regulation during embryonic development and tissue remodeling Dev Dyn 218 235 259 10842355 10.1002/(SICI)1097-0177(200006)218: 2<235::AID-DVDY2>3.0.CO;2-G 1:CAS:528:DC%2BD3cXks1Slu7c%3D (Pubitemid 30349638)
21. PL Jones FS Jones 2000 Tenascin-C in development and disease: gene regulation and cell function Matrix Biol 19 581 596 11102748 10.1016/S0945-053X(00)00106-2 1:CAS:528:DC%2BD3MXhsFCmug%3D%3D
22. K Kajiwara H Ueda H Yamamoto M Imazu Y Hayashi N Kohno 2004 Tenascin-C is associated with coronary plaque instability in patients with acute coronary syndromes Circ J 68 198 203 10.1253/circj.68.198 1:CAS:528:DC%2BD2cXisFyqtLo%3D (Pubitemid 38405009)
23. Kang WY, Jeong MH, Ahn YK, Kim JH, Chae SC, Kim YJ, Hur SH, Seong IW, Hong TJ, Choi DH, Cho MC, Kim CJ, Seung KB, Chung WS, Jang YS, Rha SW, Bae JH, Cho JG, Park SJ, Korea Acute Myocardial Infarction Registry Investigators (2009) Are patients with angiographically near-normal coronary arteries who present as acute myocardial infarction actually safe? Int J Cardiol 146(2): 202-212
24. C Kimchi-Safarty JM Oh I-W Kim ZE Sauna AM Calcagno SV Ambudkar MM Gottesman 2007 A "silent" polymorphism in the MDR1 gene changes substrate specificity Science 315 525 528 10.1126/science.1135308 (Pubitemid 46175758)
25. DF Kong LK Shaw FE Harrell LH Muhlbaier KL Lee RM Califf RH Jones 2002 Predicting survival from the coronary arteriogram: an experience-based statistical index of coronary artery disease severity J Am Coll Cardiol 39 Suppl 2 327 10.1016/S0735-1097(02)81469-3
26. DW LaFleur JA Fagin JS Forrester SA Rubin BG Sharifi 1994 Cloning and characterization of alternatively spliced isoforms of rat tenascin: platelet-derived growth factor-BB markedly stimulates expression of spliced variants of tenascin mRNA in arterial smooth muscle cells J Biol Chem 269 20757 20763 7519614 1:CAS:528:DyaK2cXmsVOltr4%3D
27. DW LaFleur J Chiang JA Fagin SM Schwartz PK Shah K Wallner JS Forrester BG Sharifi 1997 Aortic smooth muscle cells interact with tenascin-C through its fibrinogen-like domain J Biol Chem 272 32798 32803 9407055 10.1074/jbc.272.52. 32798 1:CAS:528:DyaK1cXpt1Ok (Pubitemid 28023613)
28. U Laufs D Marra K Node JK Liao 1999 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1) J Biol Chem 274 21926 21931 10419514 10.1074/jbc.274.31.21926 1:CAS:528:DyaK1MXltVymtL8%3D (Pubitemid 29360029)
29. AJ Lusis R Mar P Pajukanta 2004 Genetics of atherosclerosis Annu Rev Genomics Hun Genet 5 189 218 10.1146/annurev.genom.5.061903.175930 1:CAS:528:DC%2BD2cXosl2is7o%3D (Pubitemid 39362746)
30. ER Martin MP Bass ER Hauser NL Kaplan 2003 Accounting for linkage in family-based tests of association with missing parental genotypes Am J Hum Genet 73 1016 1026 14551902 10.1086/378779 1:CAS:528:DC%2BD3sXptVGnsrk%3D (Pubitemid 37414216)
31. A Matsuda T Hirota M Akahoshi M Shimizu M Tamari A Miyatake A Takahashi K Nakashima N Takahashi K Obara N Yuyama S Doi Y Kamogawa T Enomoto K Ohshima T Tsunoda S Miyatake K Fujita M Kusakabe Y Nakamura J Hopkin T Shirakawa 2005 Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma Hum Mol Genet 14 2779 2786 16115819 10.1093/hmg/ddi311 1:CAS:528:DC%2BD2MXhtVWnt7jN (Pubitemid 41418784)
32. DM McKean L Sisbarro D Ilic N Kaplan-Alburquerque R Nemenoff M Weiser-Evans MJ Kern PL Jones 2003 FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration J Cell Biol 161 393 402 12741393 10.1083/jcb.jcb.200302126 1:CAS:528:DC%2BD3sXjtl2itr4%3D (Pubitemid 36529856)
33. R McPherson A Pertsemlidis N Kavaslar A Stewart R Roberts DR Cox DA Hinds LA Pennacchio A Tybjaerg-Hansen AR Folsom E Boerwinkle HH Hobbs JC Cohen 2007 A common allele on chromosome 9 associated with coronary heart disease Science 316 1488 1491 17478681 10.1126/science.1142447 1:CAS:528:DC%2BD2sXmtFSjtr0%3D (Pubitemid 46906617)
34. KS Midwood JE Schwarzbauer. 2002 Tenascin-C modulates matrix contraction via focal adhesion kinase- and Rho-mediated signaling pathways Mol Biol Cell 13 3601 3613 12388760 10.1091/mbc.E02-05-0292 1:CAS:528:DC%2BD38XotFyrs7c%3D (Pubitemid 35191378)
35. GG Mokone M Gajjar AV September MP Schwellnus J Greenberg TD Noakes M Collins 2005 The guanine-thymine dinucleotide repeat polymorphism within the tenascin-C gene is associated with Achilles tendon injuries Am J Sports Med 33 1016 1021 15983124 10.1177/0363546504271986 (Pubitemid 40917551)
36. AG Nackley SA Shabalina IE Tchivileva K Satterfield O Korchynskyi SS Makarov W Maixner L Diatchenko 2006 Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure Science 314 1930 1933 17185601 10.1126/science.1131262 1:CAS:528: DC%2BD28Xhtlemt7bF (Pubitemid 46026115)
37. KB Nielsen S Sørensen L Cartegni TJ Corydon TK Doktor LD Schroeder LS Reinert O Elpeleg AR Krainer N Gregersen J Kjems BS Andresen 2007 Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: A synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer Am J Hum Genet 80 416 432 17273963 10.1086/511992 1:CAS:528:DC%2BD2sXit1Wlu7g%3D
38. Orsmark-Pietras C, Melén E, Vendelin J, Bruce S, Laitinen A, Laitinen LA, Lauener R, Riedler J, von Mutius E, Doekes G, Wickman M, van Hage M, Pershagen G, Scheynius A, Nyberg F, Kere J, The PARSIFAL Genetics Study Group (2008) Biological and genetic interaction between tenascin C and neuropeptide S receptor 1 in allergic diseases. Hum Mol Genet 17:1673-82
39. J Pas E Wyszko K Rolle L Rychlewski S Nowak R Żukiel J Barciszewski 2006 Analysis of structure and function of tenascin-C Int J Biochem Cell Biol 38 1594 1602 16698307 10.1016/j.biocel.2006.03.017 1:CAS:528:DC%2BD28XkvVGjt78%3D (Pubitemid 43729294)
40. Pedretti M, Rancic Z, Soltermann A, Herzog BA, Schliemann C, Lachat M, Neri D, and Kaufmann PA (2009) Comparative immunohistochemical staining of atherosclerotic plaques using F16, F8 and L19: three clinical-grade fully human antibodies. Atherosclerosis 208(2): 382-389
41. WA Pitman MH Hunt C McFarland B Paigen 1998 Genetic analysis of the difference in diet-induced atherosclerosis between the inbred mouse strains SM/J and NZB/BINJ Arterioscler Throm Vasc Biol 18 615 620 1:STN:280: DyaK1c3hsFWmsA%3D%3D (Pubitemid 28177902)
42. S Puget J Grill A Valent I Bieche C Dantas-Barbosa A Kauffmann P Dessen L Lacroix B Geoerger B Job C Dirven P Varlet M Peyre PB Dirks C Sainte-Rose G Vassal 2009 Candidate genes on chromosome 9q33-34 involved in the progression of childhoos ependymomas J Clin Oncol 27 1884 1892 19289631 10.1200/JCO.2007.15. 4195 1:CAS:528:DC%2BD1MXltlSisbs%3D
43. TK Rice NJ Schork DC Rao 2008 Methods for handling multiple testing Adv Genet 60 293 308 18358325 10.1016/S0065-2660(07)00412-9
44. BE Rolfe NF Worth CJ World JH Campbell GR Campbell 2005 Rho and vascular disease Atherosclerosis 183 1 16 15982657 10.1016/j.atherosclerosis.2005.04.023 1:CAS:528:DC%2BD2MXhtFWnu7jI (Pubitemid 41416816)
45. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O'Donnell C, Roger V, Sorlie P, Steinberger J, Thom T, Wilson M, Hong Y, The American Heart Association Statistics Committee and Stroke Statistics Subcommittee (2008) Heart disease and stroke statistics-2008 update. Circulation 117: e25-e146
46. Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, König IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H, The WTCCC and the Cardiogenics Consortium (2007) Genomewide association analysis of coronary artery disease. N Engl J Med 357: 443-453
47. Y Sawada K Onoda K Imanaka-Yoshida J Maruyama K Yamamoto T Yoshida H Shimpo 2007 Tenascin-C synthesized in both donor grafts and recipients accelerates artery graft stenosis Cardiovasc Res 74 366 376 17383619 10.1016/j.cardiores.2007.02.028 1:CAS:528:DC%2BD2sXlt1CjtLY%3D (Pubitemid 46693714)
48. Schunkert H, Götz A, Braund P, McGinnis R, Tregouet D-A, Mangino M, Linsel-Nitschke P, Cambien F, Hengstenberg C, Stark K, Blankenberg S, Tiret L, Ducimetiere P, Keniry A, Ghori MJR, Schreiber S, El Mokhtari NE, Hall AS, Dixon RJ, Goodall AH, Liptau H, Pollard H, Schwarz DF, Hothorn LA, Wichmann HE, König IR, Fischer M, Meisinger C, Ouwehand W, Deloukas P, Thompson JR, Erdmann J, Ziegler A, Samani NJ, The Cardiogenics Consortium (2008) Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation 117: 1675-1684
49. D Seo T Wang H Dressman EE Herderick ES Iversen C Dong K Vata CA Milano F Rigat J Pittman JR Nevins M West PJ Goldschmidt-Clermont 2004 Gene expression phenotypes of atherosclerosis Arterioscler Thromb Vasc Biol 24 1922 1927 15297278 10.1161/01.ATV.0000141358.65242.1f 1:CAS:528:DC%2BD2cXotVOnsLY%3D (Pubitemid 39350314)
50. PK Shah ZS Galis 2001 Matrix metalloproteinase hypothesis of plaque rupture: players keep piling up but questions remain Circulation 104 1878 1880 11602486 1:CAS:528:DC%2BD3MXosFCkurs%3D (Pubitemid 32983226)
51. SH Shah NJ Freedman L Zhang DR Crosslin DR Stone C Haynes J Johnson S Nelson L Wang JJ Connelly M Muehlbauer GS Ginsburg DC Crossman CJH Jones J Vance MH Sketch Jr CB Granger CB Newgard SG Gregory PJ Goldschmidt-Clermont WE Kraus ER Hauser 2009 Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis PLoS Genet 5 e1000318 19119412 10.1371/journal.pgen.1000318
52. BG Sharifi DW LaFleur CJ Pirola JS Forrester JA Fagin 1992 Angiotensin II regulates tenascin gene expression in vascular smooth muscle cells J Biol Chem 267 23910 23915 1385427 1:CAS:528:DyaK38XmtVGrsLY%3D (Pubitemid 23088203)
53. S Shea R Ottman C Gabrieli Z Stein A Nichols 1984 Family history as an independent risk factor for coronary artery disease J Am Coll Cardiol 4 793 801 6481018 10.1016/S0735-1097(84)80408-8 1:STN:280:DyaL2M%2FgslyqsQ%3D%3D (Pubitemid 14012469)
54. Smith LR, Harrell FE Jr, Rankin JS, Califf RM, Pryor DB, Muhlbaier LH, Lee KL, Mark DB, Jones RH, Oldham HN (1991) Determinants of early versus late cardiac death in patients undergoing coronary artery bypass graft surgery. Circulation 84 (Suppl 5):III245-III253
55. BS Sutton DR Crosslin SH Shah SC Nelson A Bassil AB Hale C Haynes PJ Goldschmidt-Clermont JM Vance WE Kraus SG Gregory ER Hauser 2008 Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case/control and family datasets Hum Mol Genet 17 1318 1328 18204052 10.1093/hmg/ddn020 1:CAS:528:DC%2BD1cXkvVOhurg%3D (Pubitemid 351566968)
56. D Vaidya LR Yanek TF Moy TA Pearson LC Becker DM Becker 2007 Incidence of coronary artery disease in siblings with premature coronary artery disease: 10 years of follow-up Am J Cardiol 100 1410 1415 17950799 10.1016/j.amjcard.2007. 06.031 (Pubitemid 47576019)
57. AC van der Wal AE Becker CM van der Loos PK Das 1994 Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology Circulation 89 36 44 8281670 (Pubitemid 24026469)
58. T von Lukowicz M Silacci MT Wyss E Trachsel C Lohmann A Buck TF Lüscher D Neri CM Matter 2007 Human antibody against C domain of tenascin-C visualizes murine atherosclerotic plaques ex vivo J Nucl Med 48 582 587 10.2967/jnumed.106.036046 (Pubitemid 47571414)
59. K Wallner C Li PK Shah MC Fishbein JS Forrester S Kaul BG Sharifi 1999 Tenascin-C is expressed in macrophage-rich human coronary atherosclerotic plaque Circulation 99 1284 1289 10077510 1:STN:280:DyaK1M7nslWhsw%3D%3D (Pubitemid 29129911)
60. K Wallner C Li PK Shah K-J Wu SM Schwartz BG Sharifi 2004 EGF-like domain of tenascin-C is proapoptotic for cultured smooth muscle cells Arterioscler Thromb Vasc Biol 24 1416 1421 15178565 10.1161/01.ATV.0000134299.89599.53 1:CAS:528:DC%2BD2cXmtValtb4%3D (Pubitemid 39050434)
61. L Wang ER Hauser SH Shah MA Pericak-Vance C Haynes D Crosslin M Harris S Nelson AB Hale CB Granger JL Haines CJH Jones D Crossman D Seo SG Gregory WE Kraus PJ Goldschmidt-Clermont JM Vance 2007 Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease Am J Hum Genet 80 650 663 17357071 10.1086/512981 1:CAS:528: DC%2BD2sXktVOisr8%3D (Pubitemid 46564402)
62. L Wang ER Hauser SH Shah D Seo P Sivashanmugam ST Exum SG Gregory CB Granger JL Haines CJH Jones D Crossman C Haynes WE Kraus NJ Freedman MA Pericak-Vance PJ Goldschmidt-Clermont JM Vance 2008 Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary artery disease Ann Hum Genet 72 443 453 18318786 10.1111/j.1469-1809.2008.00433.x 1:CAS:528:DC%2BD1cXptFSjtr0%3D (Pubitemid 351833743)
63. H Watkins M Farrall 2006 Genetic susceptibility to coronary artery disease: from promise to progress Nat Rev Genet 7 163 173 16462853 10.1038/nrg1805 1:CAS:528:DC%2BD28XhsFSmu7w%3D (Pubitemid 43361528)
64. Wellcome Trust Case Control Consortium 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Nature 447 661 678 10.1038/nature05911 (Pubitemid 46889737)
65. MB Wenk KS Midwood JE Schwarzbauer 2000 Tenascin-C suppresses Rho activation J Cell Biol 150 913 920 10953015 10.1083/jcb.150.4.913 1:CAS:528:DC%2BD3cXmtVelsrY%3D (Pubitemid 30663427)
66. S Won N Morris Q Lu RC Elston 2009 Choosing an optimal method to combine P-values Stat Med 28 1537 1553 19266501 10.1002/sim.3569
67. K Yamamoto K Onoda Y Sawada K Fujinaga K Imanaka-Yoshida H Shimpo T Yoshida I Yada 2005 Tenascin-C is an essential factor for neointimal hyperplasia after aortotomy in mice Cardiovasc Res 65 737 742 15664401 10.1016/j.cardiores. 2004.10.034 1:CAS:528:DC%2BD2MXmsVKktw%3D%3D (Pubitemid 40138995)