Cortical responses to a graded working memory challenge predict functional decline in mild cognitive impairment

Biological Psychiatry

Volumn 70, Issue 2, 2011, Pages 123-130

  Kochan, Nicole A ^a,c   Breakspear, Michael ^d,e,f   Valenzuela, Michael ^a   Slavin, Melissa J ^a,b   Brodaty, Henry ^a,b,c   Wen, Wei ^a,c   Trollor, Julian N ^a   Turner, Andrew ^a   Crawford, John D ^a   Sachdev, Perminder S ^a,c  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c PRINCE OF WALES HOSPITAL   (Australia)

^d BLACK DOG INSTITUTE   (Australia)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^f ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

Alzheimer disease; default mode network; functional MRI; mild cognitive impairment; prospective study; working memory

Indexed keywords

AGED; ARTICLE; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DEMENTIA; DISEASE COURSE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HIPPOCAMPUS; HUMAN; LINEAR REGRESSION ANALYSIS; MALE; MILD COGNITIVE IMPAIRMENT; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; RATING SCALE; TASK PERFORMANCE; WORKING MEMORY;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; CEREBRAL CORTEX; COGNITION DISORDERS; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; OXYGEN; REGRESSION ANALYSIS;

EID: 79959735886     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.03.006     Document Type: Article

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