Lifespan mental activity predicts diminished rate of hippocampal atrophy

PLoS ONE

Volumn 3, Issue 7, 2008, Pages

  Valenzuela, Michael J ^a,b   Sachdev, Perminder ^a,b   Wen, Wei ^a,b   Chen, Xiaohua ^a,b   Brodaty, Henry ^a,b,c  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b PRINCE OF WALES HOSPITAL   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMENTIA; FEMALE; HIPPOCAMPUS; HUMAN; HYPERTENSION; LIFESPAN; LIFETIME OF EXPERIENCES QUESTIONNAIRE; MAJOR CLINICAL STUDY; MALE; MENTAL PERFORMANCE; MOOD; NERVE DEGENERATION; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; QUANTITATIVE ANALYSIS; QUESTIONNAIRE; SCORING SYSTEM; ATROPHY; COGNITIVE DEFECT; COHORT ANALYSIS; MENTAL FUNCTION; PATHOLOGY;

AGED; ATROPHY; COGNITION DISORDERS; COHORT STUDIES; DEMENTIA; HIPPOCAMPUS; HUMANS; MENTAL PROCESSES;

EID: 50349099894     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002598     Document Type: Article

References (36)

1. Valenzuela MJ, Sachdev P (2006) Brain Reserve and Dementia: A Systematic Review. Psychological Medicine 36: 441-454.
2. Valenzuela M, Sachdev P (2006) Brain Reserve and Cognitive Decline: A Nonparametric Systematic Review. Psychological Medicine 36: 1065-1073.
3. Valenzuela M, Sachdev P (2008) Can cognitive exercise prevent the onset of dementia? A systematic review of randomized clinical trials with longitudinal follow up. American Journal of Geriatric Psychiatry in press.
4. Valenzuela MJ (2008) Brain reserve and the prevention of dementia. Current Opinion in Psychiatry 21: 296-302.
5. Valenzuela M, Breakspear M, Sachdev P (2007) Complex Mental Activity and the Ageing Brain: Molecular, Cellular and Cortical Network Mechanisms. Brain Research Reviews 56: 198-213.
6. Spires T, Grote H, Varshney N, Cordery P, van Dellen A, et al. (2004) Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease indicating a possible disease mechanism. Journal of Neuroscience 24: 2270-2276.
7. Nithianantharajah J, Hannan A (2006) Enriched environments, experience-dependent plasticity and disorders of the nervous system. Nature Reviews Neuroscience 7: 697-709.
8. Lazarov O, Robinson J, Tang Y, Hairston I, Korade-Mirnics Z, et al. (2005) Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice. Cell 120: 701-713.
9. Cracchiolo J, Mori T, Nazian S, Tan J, Potter HG, et al. (2007) Enhanced cognitive activity-over and above social or physical activity-is required to protect Alzheimer's mice against cognitive impairment, reduce Ab deposition, and increase synaptic immunostaining. Neurobiology of Learning & Memory 88: 277-294.
10. Adlard P, Perreau V, Pop V, Cotman CW (2005) Voluntary exercise decreases amyloid load in a transgenic model of Alzheimers Disease. Journal of Neuroscience 25: 4217-4221.
11. Janowsky J, Melnikova T, Fadale D, Xu G, Slunt G, et al. (2003) Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's Disease. Journal of Neuroscience 25: 5217-5224.
12. Arendash G, Garcia M, Costa D, Cracchiolo J, Wefes I, et al. (2004) Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable b-amyloid deposition. Neuroreport 15: 1751-1754.
13. Snowdon D, Kemper S, Mortimer J, Greiner L, Wekstein D, et al. (1996) Linguistic Ability in Early Life and Cognitive Function and Alzheimer's Disease in Late Life. JAMA 275: 528-532.
14. Coyle J (2003) Use it or lose it-do effortful mental activities protect against dementia? New England Journal of Medicine 348: 25.
15. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathologica 82: 239-259.
16. Jack C, Petersen R, Xu Y, O'Brien P, Smith G, et al. (1999) Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment. Neurology 52: 1397-1403.
17. Gosche K, Mortimer J, Smith C, Markesbery W, Snowdon D (2002) Hippocampal volume as an index of Alzheimer neuropathology: findings from the Nun Study. -Neurology May 28 58: 1476-1482.
18. Draganski B, Gaser C, Busch V, Schuierer G, Bogdahn U, et al. (2004) Neuroplasticity: changes in grey matter induced by training. Nature 427: 311-312.
19. Sachdev P, Brodaty H, Valenzuela M, Lorentz L, Looi J, et al. (2004) The neuropsychological profile of vascular cognitive impairment its stroke and TIA patients. Neurology 62: 912-919.
20. Wen W, Sachdev P (2004) The topography of white matter hyperintensities on brain MRI in healthy 60- to 64-year-old individuals. Neuroimage 22: 144-154.
21. Watson C, Jack C, Cendes F (1997) Volumetric magnetic resonance imaging: clinical applications and contributions to the understanding of temporal lobe epilepsy. Archives of Neurology 54: 1521-1531.
22. Anstey K, Maller J, Meslin C, Christensen H, Jorm A, et al. (2004) Hippocampal and amygdalar volumes in relation to handedness in adults aged 60-64. Neuroreport 15: 2825-2829.
23. Valenzuela MJ, Sachdev P (2007) Assessment of complex mental activity across the lifespan: development of the Lifetime of Experiences Questionnaire. Psychological Medicine 37: 1015-1025.
24. Trollor JN, Valenzuela MJ (2001) Brain ageing in the new millennium. Australian & New Zealand Journal of Psychiatry 35: 788-805.
25. Raz N (2000) Aging of the Brain and its Impact of Cognitive Performance: Integration of Structural and Functional Findings. In: Craik F, Salthouse T, eds. The Handbook of Aging and Cognition. New Jersey: Lawrence Erlbaum Associates. pp 1-90.
26. Duman R, Heninger G, Nestler E (1997) A molecular and cellular theory of depression. American Journal of Psychiatry 54: 597-606.
27. Valenzuela MJ, Jones M, Wen W, Rae C, Graham S, et al. (2003) Memory training alters hippocampal neurochemistry in healthy elderly. Neuroreport 14: 1333-1337.
28. Brustovetsky N, Brustovetsky T, Dubinsky J (2001) On the mechanisms of neuroprotection by creatine and phosphocreatine. Journal of Neurochemistry 76: 425-434.
29. Rae C, Digney A, McEwan S, Bates T (2003) Oral ereatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial. Proceedings of the Royal Society of London-Series B: Biological Sciences 270: 2147-2150.
30. Maguire E, Gadlan D, Johnsrude I, Good C, Ashburner J, et al. (2000) Navigation-related structural change in the hippocampi of taxi drivers. Proceeding of the National Academy of Sciences, USA 97: 4398-4403.
31. Pham T, et al. (1999) Changes in brain nerve growth factor levels and nerve growth factor receptors in rats exposed to environmental enrichment for one year. Neuroscience 94: 279-286.
32. Ickes B, Pham T, Sanders L, Albeck D, Mohammed A, et al. (2000) Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain. Experimental Neurology 164: 45-52.
33. Naka F, Narita N, Okado N, Narita M (2005) Modification of AMPA receptor properties following environmental enrichment. Brain & Development 27: 275-278.
34. Kempermann G (2006) Adult Neurogenesis. New York: Oxford University Press.
35. Nithianantharajah J, Levis H, Murphy M (2004) Environmental enrichment results in cortical and subcortical changes in levels of synaptophysin and PSD-95 proteins. Neurobiology of Learning & Memory 81: 200-210.
36. Isaacs K, Anderson B, Alcantara A, Black J, Greenough W (1992) Exercise and the brain: angiogenesis in the adult rat cerebellum after vigorous physical activity and motor skill learning. Journal of Cerebral Blood Flow & Metabolism 12: 110-119.