메뉴 건너뛰기




Volumn 519, Issue 12, 2011, Pages 2353-2378

Recovery and aging of serotonergic fibers after single and intermittent MDMA treatment in dark agouti rat

Author keywords

3,4 methylenedioxymethamphetamine (MDMA; ecstasy); Aging, tryptophan hydroxylase 2 (Tph2); Brain derived neurotrophic factor (BDNF); Serotonin (5 HT)

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROTROPHIC FACTOR;

EID: 79959735168     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.22631     Document Type: Article
Times cited : (16)

References (70)
  • 1
    • 0343238881 scopus 로고    scopus 로고
    • Early microglial reaction following mild forebrain ischemia induced by common carotid artery occlusion in rats
    • Abraham H, Lazar G. 2000. Early microglial reaction following mild forebrain ischemia induced by common carotid artery occlusion in rats. Brain Res 862: 63-73.
    • (2000) Brain Res , vol.862 , pp. 63-73
    • Abraham, H.1    Lazar, G.2
  • 2
    • 33744732146 scopus 로고    scopus 로고
    • Damage of serotonergic axons and immunolocalization of Hsp27, Hsp72, and Hsp90 molecular chaperones after a single dose of MDMA administration in Dark Agouti rat: temporal, spatial, and cellular patterns
    • Adori C, Ando RD, Kovacs GG, Bagdy G. 2006. Damage of serotonergic axons and immunolocalization of Hsp27, Hsp72, and Hsp90 molecular chaperones after a single dose of MDMA administration in Dark Agouti rat: temporal, spatial, and cellular patterns. J Comp Neurol 497: 251-269.
    • (2006) J Comp Neurol , vol.497 , pp. 251-269
    • Adori, C.1    Ando, R.D.2    Kovacs, G.G.3    Bagdy, G.4
  • 3
    • 77953609957 scopus 로고    scopus 로고
    • Elevated BDNF protein level in cortex but not in hippocampus of MDMA-treated Dark Agouti rats: a potential link to the long-term recovery of serotonergic axons
    • Adori C, Ando RD, Ferrington L, Szekeres M, Vas S, Kelly PT, Hunyady L, Bagdy G. 2010a. Elevated BDNF protein level in cortex but not in hippocampus of MDMA-treated Dark Agouti rats: a potential link to the long-term recovery of serotonergic axons. Neurosci Lett 478: 56-60.
    • (2010) Neurosci Lett , vol.478 , pp. 56-60
    • Adori, C.1    Ando, R.D.2    Ferrington, L.3    Szekeres, M.4    Vas, S.5    Kelly, P.T.6    Hunyady, L.7    Bagdy, G.8
  • 6
    • 74449083688 scopus 로고    scopus 로고
    • Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion
    • Ando RD, Adori C, Kirilly E, Molnar E, Kovacs GG, Ferrington L, Kelly PA, Bagdy G. 2010. Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion. Behav Brain Res 207: 280-289.
    • (2010) Behav Brain Res , vol.207 , pp. 280-289
    • Ando, R.D.1    Adori, C.2    Kirilly, E.3    Molnar, E.4    Kovacs, G.G.5    Ferrington, L.6    Kelly, P.A.7    Bagdy, G.8
  • 8
    • 2542602190 scopus 로고    scopus 로고
    • Effects of a single dose of 3,4-methylenedioxymethamphetamine on circadian patterns, motor activity and sleep in drug-naive rats and rats previously exposed to MDMA
    • Balogh B, Molnar E, Jakus R, Quate L, Olverman HJ, Kelly PA, Kantor S, Bagdy G. 2004. Effects of a single dose of 3, 4-methylenedioxymethamphetamine on circadian patterns, motor activity and sleep in drug-naive rats and rats previously exposed to MDMA. Psychopharmacology (Berl) 173: 296-309.
    • (2004) Psychopharmacology (Berl) , vol.173 , pp. 296-309
    • Balogh, B.1    Molnar, E.2    Jakus, R.3    Quate, L.4    Olverman, H.J.5    Kelly, P.A.6    Kantor, S.7    Bagdy, G.8
  • 9
    • 59149105577 scopus 로고    scopus 로고
    • Differential regulation of psychostimulant-induced gene expression of brain derived neurotrophic factor and the immediate-early gene Arc in the juvenile and adult brain
    • Banerjee PS, Aston J, Khundakar AA, Zetterstrom TS. 2009. Differential regulation of psychostimulant-induced gene expression of brain derived neurotrophic factor and the immediate-early gene Arc in the juvenile and adult brain. Eur J Neurosci 29: 465-476.
    • (2009) Eur J Neurosci , vol.29 , pp. 465-476
    • Banerjee, P.S.1    Aston, J.2    Khundakar, A.A.3    Zetterstrom, T.S.4
  • 10
    • 47249116917 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine induces differential regulation of tryptophan hydroxylase 2 protein and mRNA levels in the rat dorsal raphe nucleus
    • Bonkale WL, Austin MC. 2008. 3, 4-Methylenedioxymethamphetamine induces differential regulation of tryptophan hydroxylase 2 protein and mRNA levels in the rat dorsal raphe nucleus. Neuroscience 155: 270-276.
    • (2008) Neuroscience , vol.155 , pp. 270-276
    • Bonkale, W.L.1    Austin, M.C.2
  • 11
    • 0035077417 scopus 로고    scopus 로고
    • Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine
    • Callahan BT, Cord BJ, Ricaurte GA. 2001. Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine. Synapse 40: 113-121.
    • (2001) Synapse , vol.40 , pp. 113-121
    • Callahan, B.T.1    Cord, B.J.2    Ricaurte, G.A.3
  • 13
    • 67650848350 scopus 로고    scopus 로고
    • How bad is accelerated senescence in consumers of drugs of abuse?
    • Carvalho F. 2009. How bad is accelerated senescence in consumers of drugs of abuse? Adicciones 21: 99-104.
    • (2009) Adicciones , vol.21 , pp. 99-104
    • Carvalho, F.1
  • 14
    • 45049085400 scopus 로고    scopus 로고
    • Developmental exposure to 3,4-methylenedioxymethamphetamine results in downregulation of neurogenesis in the adult mouse hippocampus
    • Cho KO, Rhee GS, Kwack SJ, Chung SY, Kim SY. 2008. Developmental exposure to 3, 4-methylenedioxymethamphetamine results in downregulation of neurogenesis in the adult mouse hippocampus. Neuroscience 154: 1034-1041.
    • (2008) Neuroscience , vol.154 , pp. 1034-1041
    • Cho, K.O.1    Rhee, G.S.2    Kwack, S.J.3    Chung, S.Y.4    Kim, S.Y.5
  • 15
    • 0027462464 scopus 로고
    • 5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine
    • Colado MI, Murray TK, Green AR. 1993. 5-HT loss in rat brain following 3, 4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine. Br J Pharmacol 108: 583-589.
    • (1993) Br J Pharmacol , vol.108 , pp. 583-589
    • Colado, M.I.1    Murray, T.K.2    Green, A.R.3
  • 16
    • 0023748135 scopus 로고
    • A monoclonal antibody to aromatic amino acid hydroxylases. Identification of the epitope
    • Cotton RG, McAdam W, Jennings I, Morgan FJ. 1988. A monoclonal antibody to aromatic amino acid hydroxylases. Identification of the epitope. Biochem J 255: 193-196.
    • (1988) Biochem J , vol.255 , pp. 193-196
    • Cotton, R.G.1    McAdam, W.2    Jennings, I.3    Morgan, F.J.4
  • 17
    • 0026394899 scopus 로고
    • Age-related changes in serotonin-immunoreactivity in the telencephalon and diencephalon of rats
    • Davidoff MS, Lolova IS. 1991. Age-related changes in serotonin-immunoreactivity in the telencephalon and diencephalon of rats. J Hirnforsch 32: 745-753.
    • (1991) J Hirnforsch , vol.32 , pp. 745-753
    • Davidoff, M.S.1    Lolova, I.S.2
  • 18
    • 4544314351 scopus 로고    scopus 로고
    • Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans
    • de la Torre R, Farre M. 2004. Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans. Trends Pharmacol Sci 25: 505-508.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 505-508
    • de la Torre, R.1    Farre, M.2
  • 19
    • 0029125154 scopus 로고
    • Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")
    • Fischer C, Hatzidimitriou G, Wlos J, Katz J, Ricaurte G. 1995. Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3, 4-methylenedioxymethamphetamine (MDMA, "ecstasy"). J Neurosci 15: 5476-5485.
    • (1995) J Neurosci , vol.15 , pp. 5476-5485
    • Fischer, C.1    Hatzidimitriou, G.2    Wlos, J.3    Katz, J.4    Ricaurte, G.5
  • 23
    • 0041466261 scopus 로고    scopus 로고
    • The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")
    • Green AR, Mechan AO, Elliott JM, O'Shea E, Colado MI. 2003. The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacol Rev 55: 463-508.
    • (2003) Pharmacol Rev , vol.55 , pp. 463-508
    • Green, A.R.1    Mechan, A.O.2    Elliott, J.M.3    O'Shea, E.4    Colado, M.I.5
  • 24
    • 27644549457 scopus 로고    scopus 로고
    • In situ expression of brain-derived neurotrophic factor or neurotrophin-3 promotes sprouting of cortical serotonergic axons following a neurotoxic lesion
    • Grider MH, Mamounas LA, Le W, Shine HD. 2005. In situ expression of brain-derived neurotrophic factor or neurotrophin-3 promotes sprouting of cortical serotonergic axons following a neurotoxic lesion. J Neurosci Res 82: 404-412.
    • (2005) J Neurosci Res , vol.82 , pp. 404-412
    • Grider, M.H.1    Mamounas, L.A.2    Le, W.3    Shine, H.D.4
  • 26
    • 60749103570 scopus 로고    scopus 로고
    • Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice
    • Gutknecht L, Kriegebaum C, Waider J, Schmitt A, Lesch KP. 2009. Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice. Eur Neuropsychopharmacol 19: 266-282.
    • (2009) Eur Neuropsychopharmacol , vol.19 , pp. 266-282
    • Gutknecht, L.1    Kriegebaum, C.2    Waider, J.3    Schmitt, A.4    Lesch, K.P.5
  • 28
    • 0033564773 scopus 로고    scopus 로고
    • Altered serotonin innervation patterns in the forebrain of monkeys treated with (+/-)3,4-methylenedioxymethamphetamine seven years previously: factors influencing abnormal recovery
    • Hatzidimitriou G, McCann UD, Ricaurte GA. 1999. Altered serotonin innervation patterns in the forebrain of monkeys treated with (+/-)3, 4-methylenedioxymethamphetamine seven years previously: factors influencing abnormal recovery. J Neurosci 19: 5096-5107.
    • (1999) J Neurosci , vol.19 , pp. 5096-5107
    • Hatzidimitriou, G.1    McCann, U.D.2    Ricaurte, G.A.3
  • 29
    • 2542541218 scopus 로고    scopus 로고
    • Preliminary evidence of hippocampal dysfunction in adolescent MDMA ("ecstasy") users: possible relationship to neurotoxic effects
    • Jacobsen LK, Mencl WE, Pugh KR, Skudlarski P, Krystal JH. 2004. Preliminary evidence of hippocampal dysfunction in adolescent MDMA ("ecstasy") users: possible relationship to neurotoxic effects. Psychopharmacology (Berl) 173: 383-390.
    • (2004) Psychopharmacology (Berl) , vol.173 , pp. 383-390
    • Jacobsen, L.K.1    Mencl, W.E.2    Pugh, K.R.3    Skudlarski, P.4    Krystal, J.H.5
  • 30
    • 0035161362 scopus 로고    scopus 로고
    • Causes of Alzheimer's disease: paracetamol (acetaminophen) today? Amphetamines tomorrow?
    • Jones GR. 2001. Causes of Alzheimer's disease: paracetamol (acetaminophen) today? Amphetamines tomorrow? Med Hypotheses 56: 121-123.
    • (2001) Med Hypotheses , vol.56 , pp. 121-123
    • Jones, G.R.1
  • 31
    • 0035812889 scopus 로고    scopus 로고
    • Histological changes in monoaminergic neurons of Long-Evans Cinnamon rats
    • Kawano H, Takeuchi Y, Yoshimoto K, Matsumoto K, Sugimoto T. 2001. Histological changes in monoaminergic neurons of Long-Evans Cinnamon rats. Brain Res 915: 25-31.
    • (2001) Brain Res , vol.915 , pp. 25-31
    • Kawano, H.1    Takeuchi, Y.2    Yoshimoto, K.3    Matsumoto, K.4    Sugimoto, T.5
  • 32
    • 0036899022 scopus 로고    scopus 로고
    • Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain
    • Kelly PA, Ritchie IM, Quate L, McBean DE, Olverman HJ. 2002. Functional consequences of perinatal exposure to 3, 4-methylenedioxymethamphetamine in rat brain. Br J Pharmacol 137: 963-970.
    • (2002) Br J Pharmacol , vol.137 , pp. 963-970
    • Kelly, P.A.1    Ritchie, I.M.2    Quate, L.3    McBean, D.E.4    Olverman, H.J.5
  • 33
    • 67049098280 scopus 로고    scopus 로고
    • S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA
    • Kindlundh-Hogberg AM, Zhang X, Svenningsson P. 2009. S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA. Int J Neuropsychopharmacol 12: 201-215.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 201-215
    • Kindlundh-Hogberg, A.M.1    Zhang, X.2    Svenningsson, P.3
  • 34
    • 50849127886 scopus 로고    scopus 로고
    • Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days
    • Kirilly E, Molnar E, Balogh B, Kantor S, Hansson SR, Palkovits M, Bagdy G. 2008. Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days. Int J Neuropsychopharmacol 11: 795-809.
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 795-809
    • Kirilly, E.1    Molnar, E.2    Balogh, B.3    Kantor, S.4    Hansson, S.R.5    Palkovits, M.6    Bagdy, G.7
  • 36
    • 33847694981 scopus 로고    scopus 로고
    • Single dose of MDMA causes extensive decrement of serotoninergic fibre density without blockage of the fast axonal transport in Dark Agouti rat brain and spinal cord
    • Kovacs GG, Ando RD, Adori C, Kirilly E, Benedek A, Palkovits M, Bagdy G. 2007. Single dose of MDMA causes extensive decrement of serotoninergic fibre density without blockage of the fast axonal transport in Dark Agouti rat brain and spinal cord. Neuropathol Appl Neurobiol 33: 193-203.
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 193-203
    • Kovacs, G.G.1    Ando, R.D.2    Adori, C.3    Kirilly, E.4    Benedek, A.5    Palkovits, M.6    Bagdy, G.7
  • 37
    • 0030087725 scopus 로고    scopus 로고
    • Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies
    • Lew R, Sabol KE, Chou C, Vosmer GL, Richards J, Seiden LS. 1996. Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies. J Pharmacol Exp Ther 276: 855-865.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 855-865
    • Lew, R.1    Sabol, K.E.2    Chou, C.3    Vosmer, G.L.4    Richards, J.5    Seiden, L.S.6
  • 38
    • 79959745336 scopus 로고
    • Aberrant reinnervation of rat cerebral cortex by serotonergic axons after denervation by p-chloroamphetamine (PCA). Soc Neurosci Abs. p
    • Mamounas LA, Molliver ME. 1991. Aberrant reinnervation of rat cerebral cortex by serotonergic axons after denervation by p-chloroamphetamine (PCA). Soc Neurosci Abs. p 1181.
    • (1991) , pp. 1181
    • Mamounas, L.A.1    Molliver, M.E.2
  • 39
    • 79959760453 scopus 로고
    • Abnormal morphology of regenerated 5-HT axons in rat cerebral cortex one year after ablation by p-chloroamphetamine (PCA): accelerated aging of serotonergic projections. Soc Neurosci Abs. p
    • Mamounas LA, Axt KJ, Molliver ME. 1992. Abnormal morphology of regenerated 5-HT axons in rat cerebral cortex one year after ablation by p-chloroamphetamine (PCA): accelerated aging of serotonergic projections. Soc Neurosci Abs. p 629.
    • (1992) , pp. 629
    • Mamounas, L.A.1    Axt, K.J.2    Molliver, M.E.3
  • 40
    • 0029584365 scopus 로고
    • Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
    • Mamounas LA, Blue ME, Siuciak JA, Altar CA. 1995. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. J Neurosci 15: 7929-7939.
    • (1995) J Neurosci , vol.15 , pp. 7929-7939
    • Mamounas, L.A.1    Blue, M.E.2    Siuciak, J.A.3    Altar, C.A.4
  • 41
    • 0034651078 scopus 로고    scopus 로고
    • BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain
    • Mamounas LA, Altar CA, Blue ME, Kaplan DR, Tessarollo L, Lyons WE. 2000. BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. J Neurosci 20: 771-782.
    • (2000) J Neurosci , vol.20 , pp. 771-782
    • Mamounas, L.A.1    Altar, C.A.2    Blue, M.E.3    Kaplan, D.R.4    Tessarollo, L.5    Lyons, W.E.6
  • 42
    • 33646792970 scopus 로고    scopus 로고
    • Differential effects of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on BDNF mRNA expression in rat frontal cortex and hippocampus
    • Martinez-Turrillas R, Moyano S, Del Rio J, Frechilla D. 2006. Differential effects of 3, 4-methylenedioxymethamphetamine (MDMA, "ecstasy") on BDNF mRNA expression in rat frontal cortex and hippocampus. Neurosci Lett 402: 126-130.
    • (2006) Neurosci Lett , vol.402 , pp. 126-130
    • Martinez-Turrillas, R.1    Moyano, S.2    Del Rio, J.3    Frechilla, D.4
  • 43
    • 4544328810 scopus 로고    scopus 로고
    • BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders
    • Mattson MP, Maudsley S, Martin B. 2004. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends Neurosci 27: 589-594.
    • (2004) Trends Neurosci , vol.27 , pp. 589-594
    • Mattson, M.P.1    Maudsley, S.2    Martin, B.3
  • 44
    • 53549121196 scopus 로고    scopus 로고
    • Development and characterization of a novel animal model of intermittent MDMA ("Ecstasy") exposure during adolescence
    • Meyer JS, Piper BJ, Vancollie VE. 2008. Development and characterization of a novel animal model of intermittent MDMA ("Ecstasy") exposure during adolescence. Ann N Y Acad Sci 1139: 151-163.
    • (2008) Ann N Y Acad Sci , vol.1139 , pp. 151-163
    • Meyer, J.S.1    Piper, B.J.2    Vancollie, V.E.3
  • 46
    • 0002209037 scopus 로고
    • The use of interspecies scaling in toxicokinetics
    • In: Yacogi A, Kelly J, Batra V, editors. New York: Pergamon Press. p -
    • Mordenti J, Chappell W. 1989. The use of interspecies scaling in toxicokinetics. In: Yacogi A, Kelly J, Batra V, editors. Toxicokinetics and new drug development. New York: Pergamon Press. p 42-96.
    • (1989) Toxicokinetics and new drug development , pp. 42-96
    • Mordenti, J.1    Chappell, W.2
  • 47
    • 0033588210 scopus 로고    scopus 로고
    • Age-related decrease in brain-derived neurotrophic factor gene expression in the brain of the zitter rat with genetic spongiform encephalopathy
    • Muto Y, Hayashi T, Higashi Y, Endo T, Yamamoto T, Sato K. 1999. Age-related decrease in brain-derived neurotrophic factor gene expression in the brain of the zitter rat with genetic spongiform encephalopathy. Neurosci Lett 271: 69-72.
    • (1999) Neurosci Lett , vol.271 , pp. 69-72
    • Muto, Y.1    Hayashi, T.2    Higashi, Y.3    Endo, T.4    Yamamoto, T.5    Sato, K.6
  • 49
    • 0031879806 scopus 로고    scopus 로고
    • The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ('ecstasy')
    • O'Shea E, Granados R, Esteban B, Colado MI, Green AR. 1998. The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ('ecstasy'). Neuropharmacology 37: 919-926.
    • (1998) Neuropharmacology , vol.37 , pp. 919-926
    • O'Shea, E.1    Granados, R.2    Esteban, B.3    Colado, M.I.4    Green, A.R.5
  • 50
    • 12444321929 scopus 로고    scopus 로고
    • Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or ecstasy
    • Parrott AC. 2005. Chronic tolerance to recreational MDMA (3, 4-methylenedioxymethamphetamine) or ecstasy. J Psychopharmacol 19: 71-83.
    • (2005) J Psychopharmacol , vol.19 , pp. 71-83
    • Parrott, A.C.1
  • 52
    • 0035503298 scopus 로고    scopus 로고
    • Cutaneous vasoconstriction contributes to hyperthermia induced by 3,4-methylenedioxymethamphetamine (ecstasy) in conscious rabbits
    • Pedersen NP, Blessing WW. 2001. Cutaneous vasoconstriction contributes to hyperthermia induced by 3, 4-methylenedioxymethamphetamine (ecstasy) in conscious rabbits. J Neurosci 21: 8648-8654.
    • (2001) J Neurosci , vol.21 , pp. 8648-8654
    • Pedersen, N.P.1    Blessing, W.W.2
  • 53
    • 33645887834 scopus 로고    scopus 로고
    • Repeated adolescent 3,4-methylenedioxymethamphetamine (MDMA) exposure in rats attenuates the effects of a subsequent challenge with MDMA or a 5-hydroxytryptamine(1A) receptor agonist
    • Piper BJ, Vu HL, Safain MG, Oliver AJ, Meyer JS. 2006. Repeated adolescent 3, 4-methylenedioxymethamphetamine (MDMA) exposure in rats attenuates the effects of a subsequent challenge with MDMA or a 5-hydroxytryptamine(1A) receptor agonist. J Pharmacol Exp Ther 317: 838-849.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 838-849
    • Piper, B.J.1    Vu, H.L.2    Safain, M.G.3    Oliver, A.J.4    Meyer, J.S.5
  • 54
    • 2542544234 scopus 로고    scopus 로고
    • Acute methylenedioxymethamphetamine administration: effects on local cerebral blood flow and glucose utilisation in the Dark Agouti rat
    • Quate L, McBean DE, Ritchie IM, Olverman HJ, Kelly PA. 2004. Acute methylenedioxymethamphetamine administration: effects on local cerebral blood flow and glucose utilisation in the Dark Agouti rat. Psychopharmacology (Berl) 173: 287-295.
    • (2004) Psychopharmacology (Berl) , vol.173 , pp. 287-295
    • Quate, L.1    McBean, D.E.2    Ritchie, I.M.3    Olverman, H.J.4    Kelly, P.A.5
  • 56
    • 0030087890 scopus 로고    scopus 로고
    • Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations
    • Sabol KE, Lew R, Richards JB, Vosmer GL, Seiden LS. 1996. Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations. J Pharmacol Exp Ther 276: 846-854.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 846-854
    • Sabol, K.E.1    Lew, R.2    Richards, J.B.3    Vosmer, G.L.4    Seiden, L.S.5
  • 57
    • 28844490870 scopus 로고    scopus 로고
    • An open letter to our readers on the use of antibodies
    • Saper CB. 2005. An open letter to our readers on the use of antibodies. J Comp Neurol 493: 477-478.
    • (2005) J Comp Neurol , vol.493 , pp. 477-478
    • Saper, C.B.1
  • 59
    • 54049154612 scopus 로고    scopus 로고
    • (+/-)-3,4-Methylenedioxymethamphetamine treatment in adult rats impairs path integration learning: a comparison of single vs once per week treatment for 5 weeks
    • Skelton MR, Able JA, Grace CE, Herring NR, Schaefer TL, Gudelsky GA, Vorhees CV, Williams MT. 2008. (+/-)-3, 4-Methylenedioxymethamphetamine treatment in adult rats impairs path integration learning: a comparison of single vs once per week treatment for 5 weeks. Neuropharmacology 55: 1121-1130.
    • (2008) Neuropharmacology , vol.55 , pp. 1121-1130
    • Skelton, M.R.1    Able, J.A.2    Grace, C.E.3    Herring, N.R.4    Schaefer, T.L.5    Gudelsky, G.A.6    Vorhees, C.V.7    Williams, M.T.8
  • 60
    • 0023484528 scopus 로고
    • Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat
    • Stone DM, Merchant KM, Hanson GR, Gibb JW. 1987. Immediate and long-term effects of 3, 4-methylenedioxymethamphetamine on serotonin pathways in brain of rat. Neuropharmacology 26: 1677-1683.
    • (1987) Neuropharmacology , vol.26 , pp. 1677-1683
    • Stone, D.M.1    Merchant, K.M.2    Hanson, G.R.3    Gibb, J.W.4
  • 61
    • 0025874542 scopus 로고
    • Collateral sprouting of serotonergic fibers in the cingulate cortex and the septum following cortical-hippocampal lesions
    • Ueda S, Sano Y, Kawata M. 1991. Collateral sprouting of serotonergic fibers in the cingulate cortex and the septum following cortical-hippocampal lesions. Brain Res 556: 329-332.
    • (1991) Brain Res , vol.556 , pp. 329-332
    • Ueda, S.1    Sano, Y.2    Kawata, M.3
  • 62
    • 0023798706 scopus 로고
    • Aberrant morphology of serotonergic fibers in the forebrain of the aged rat
    • van Luijtelaar MG, Steinbusch HW, Tonnaer JA. 1988. Aberrant morphology of serotonergic fibers in the forebrain of the aged rat. Neurosci Lett 95: 93-96.
    • (1988) Neurosci Lett , vol.95 , pp. 93-96
    • van Luijtelaar, M.G.1    Steinbusch, H.W.2    Tonnaer, J.A.3
  • 63
    • 0026603327 scopus 로고
    • Aging of the serotonergic system in the rat forebrain: an immunocytochemical and neurochemical study
    • van Luijtelaar MG, Tonnaer JA, Steinbusch HW. 1992. Aging of the serotonergic system in the rat forebrain: an immunocytochemical and neurochemical study. Neurobiol Aging 13: 201-215.
    • (1992) Neurobiol Aging , vol.13 , pp. 201-215
    • van Luijtelaar, M.G.1    Tonnaer, J.A.2    Steinbusch, H.W.3
  • 64
    • 0032773876 scopus 로고    scopus 로고
    • Genetic differences in spatial learning between Dark Agouti and Sprague-Dawley strains: possible correlation with the CYP2D2 polymorphism in rats treated neonatally with methamphetamine
    • Vorhees CV, Morford LL, Inman SL, Reed TM, Schilling MA, Cappon GD, Moran MS, Nebert DW. 1999. Genetic differences in spatial learning between Dark Agouti and Sprague-Dawley strains: possible correlation with the CYP2D2 polymorphism in rats treated neonatally with methamphetamine. Pharmacogenetics 9: 171-181.
    • (1999) Pharmacogenetics , vol.9 , pp. 171-181
    • Vorhees, C.V.1    Morford, L.L.2    Inman, S.L.3    Reed, T.M.4    Schilling, M.A.5    Cappon, G.D.6    Moran, M.S.7    Nebert, D.W.8
  • 65
    • 21344451390 scopus 로고    scopus 로고
    • Degeneration of monoaminergic fibers in the aged micrencephalic rat
    • Watabe Y, Yoshimoto K, Eguchi M, Ueda S. 2005. Degeneration of monoaminergic fibers in the aged micrencephalic rat. Neurosci Lett 385: 82-86.
    • (2005) Neurosci Lett , vol.385 , pp. 82-86
    • Watabe, Y.1    Yoshimoto, K.2    Eguchi, M.3    Ueda, S.4
  • 67
    • 0034911130 scopus 로고    scopus 로고
    • Ecstasy pill testing: harm minimization gone too far?
    • Winstock AR, Wolff K, Ramsey J. 2001. Ecstasy pill testing: harm minimization gone too far? Addiction 96: 1139-1148.
    • (2001) Addiction , vol.96 , pp. 1139-1148
    • Winstock, A.R.1    Wolff, K.2    Ramsey, J.3
  • 70
    • 0029760138 scopus 로고    scopus 로고
    • Molecular mechanisms of microglial activation
    • Zielasek J, Hartung HP. 1996. Molecular mechanisms of microglial activation. Adv Neuroimmunol 6: 191-122.
    • (1996) Adv Neuroimmunol , vol.6 , pp. 191-122
    • Zielasek, J.1    Hartung, H.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.