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Volumn 6, Issue 7, 2011, Pages 1193-1198

Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors

(11) Schlimme, Sonja a Hauser, Alexander Thomas b Carafa, Vincenzo c Heinke, Ralf a Kannan, Srinivasaraghavan a Stolfa, Diana A b,d Cellamare, Saverio d Carotti, Angelo d Altucci, Lucia c Jung, Manfred b Sippl, Wolfgang a

a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG (Germany)

b UNIVERSITY OF FREIBURG (Germany)

c SECOND UNIVERSITY OF NAPLES (Italy)

d UNIVERSITY OF BARI (Italy)

Author keywords

Carbamates; Epigenetics; Histone deacetylases; Virtual screening

Indexed keywords

CARBAMIC ACID; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; PRODRUG; TUBULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CRYSTAL STRUCTURE; DNA BINDING MOTIF; DRUG SCREENING; DRUG SELECTIVITY; ENZYME INHIBITION; HISTONE ACETYLATION; HUMAN; IC 50; IN VITRO STUDY; INHIBITION KINETICS; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; VIRTUAL REALITY; WESTERN BLOTTING;

CARBAMATES; COMPUTER SIMULATION; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; PRODRUGS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79959729788 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100007 Document Type: Article

Times cited : (40)

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