The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy

Nuclear Medicine and Biology

Volumn 38, Issue 5, 2011, Pages 659-666

  Cai, Hancheng ^a,b   Li, Zibo ^a   Conti, Peter S ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

18F labeling; 18F FAU; 18F FBAU; 18F FCAU; 18F FEAU; 18F FFAU; 18F FIAU; PET; Radiosynthesis

Indexed keywords

2' DEOXY 2' FLUORO 1 BETA DEXTRO ARABINOFURANOSYLURACIL F 18; 2' DEOXY 2' FLUORO 5 BROMO 1 BETA DEXTRO ARABINOFURANOSYLURACIL F 18; 2' DEOXY 2' FLUORO 5 CHLORO 1 BETA DEXTRO ARABINOFURANOSYLURACIL F 18; 2' DEOXY 2' FLUORO 5 FLUORO 1 BETA DEXTRO ARABINOFURANOSYLURACIL F 18; 5 ETHYL 2' FLUOROURACIL ARABINOSIDE F 18; CLEVUDINE F 18; FIALURIDINE F 18; HEXAMETHYLDISILOXANE; RADIOPHARMACEUTICAL AGENT; TRACER; TRIFLUOROMETHANESULFONIC ACID TRIMETHYLSILYL ESTER; TRIMETHYLSILYL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG HYDROLYSIS; DRUG PURITY; DRUG SYNTHESIS; FEASIBILITY STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; ONE POT SYNTHESIS; RADIOACTIVITY; RADIOCHEMISTRY; RADIOSYNTHESIS; REACTION TIME; SYNTHESIS;

ARABINOFURANOSYLURACIL; BROMOURACIL; FLUOROURACIL; RADIOCHEMISTRY; REFERENCE STANDARDS;

EID: 79959684879     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2011.01.003     Document Type: Article

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