Herpes simplex virus thymidine kinase imaging in mice with (1-(2′-deoxy-2′-[18F]fluoro-1-β-D-arabinofuranosyl)- 5-iodouracil) and metabolite (1-(2′-deoxy-2′-[18F]fluoro- 1-β-D-arabinofuranosyl)-5-uracil)

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 36, Issue 12, 2009, Pages 1987-1993

  Nimmagadda, Sridhar ^a,b   Mangner, Thomas J ^a   Lawhorn Crews, Jawana M ^a,b   Haberkorn, Uwe ^c   Shields, Anthony F ^a,b  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

18F; FIAU; Gene expression; HSV TK; Metabolism; PET imaging

Indexed keywords

1 (2' DEOXY 2' FLUORO BETA DEXTRO ARABINOFURANOSYL) 5 URACIL; DRUG METABOLITE; FIALURIDINE; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG UPTAKE; GENE EXPRESSION; HERPES SIMPLEX VIRUS; IMAGE ANALYSIS; MOUSE; NON INVASIVE MEASUREMENT; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; ARABINOFURANOSYLURACIL; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; FLUORINE RADIOISOTOPES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MICE; MOLECULAR IMAGING; RATS; SIMPLEXVIRUS; SUBSTRATE SPECIFICITY; THYMIDINE KINASE;

EID: 71849100449     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-009-1177-y     Document Type: Article

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