Chemical modulation of peptoids: Synthesis and conformational studies on partially constrained derivatives

Chemistry - A European Journal

Volumn 17, Issue 28, 2011, Pages 7927-7939

  Moure, Alejandra ^a   Sanclimens, Glòria ^a   Bujons, Jordi ^a   Masip, Isabel ^a   Alvarez Larena, Angel ^b   Pérez Payá, Enrique ^c   Alfonso, Ignacio ^a   Messeguer, Angel ^a  

^a INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

conformation analysis; heterocycles; NMR spectroscopy; peptidomimetics; solid phase synthesis

Indexed keywords

ACTIVE COMPOUNDS; APOPTOSIS INHIBITORS; BIO-MOLECULAR; BIOLOGICAL TARGETS; CIS ISOMERS; CIS/TRANS ISOMERIZATION; COMPARATIVE STUDIES; CONFORMATION ANALYSIS; CONFORMATIONAL BEHAVIOR; CONFORMATIONAL FLEXIBILITY; CONFORMATIONAL STUDY; DIFFERENT SOLVENTS; ENERGETIC BARRIERS; ENTROPIC CONTRIBUTIONS; EQUILIBRIUM PROCESS; HETEROCYCLES; HETEROCYCLIC MOIETIES; HYDROGEN-BONDING PATTERNS; INTERCONVERSION BARRIERS; INTERCONVERSIONS; LINE-SHAPE ANALYSIS; NMR SPECTROSCOPIC ANALYSIS; NMR SPECTRUM; NONPOLAR ENVIRONMENT; PEPTIDOMIMETICS; PEPTOIDS; RELATIVE STABILITIES; SOLID PHASE SYNTHESIS; SPECTROSCOPIC STUDIES; STRUCTURAL STUDIES; TERTIARY AMIDES; TIME-SCALES; VARIABLE-TEMPERATURE NMR; X-RAY STUDIES;

AMIDES; CELL DEATH; CONFORMATIONS; HYDROGEN; HYDROGEN BONDS; ISOMERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS (CHEMICAL);

SPECTROSCOPIC ANALYSIS;

AMIDE; PEPTIDOMIMETIC AGENT; PEPTOID;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; HYDROGEN BOND; ISOMERISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

AMIDES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HYDROGEN BONDING; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PEPTIDOMIMETICS; PEPTOIDS; PROTEIN CONFORMATION;

EID: 79959674242     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201100216     Document Type: Article

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