An evolutionarily 'young' lysine residue in histone h3 attenuates transcriptional output in saccharomyces cerevisiae

Genes and Development

Volumn 25, Issue 12, 2011, Pages 1306-1319

  Hyland, Edel M ^a,c   Molina, Henrik ^a,d   Poorey, Kunal ^b   Jie, Chunfa ^a   Xie, Zhi ^a   Dai, Junbiao ^a,e   Qian, Jiang ^a   Bekiranov, Stefan ^b   Auble, David T ^b   Pandey, Akhilesh ^a   Boeke, Jef D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c HARVARD UNIVERSITY   (United States)

^d CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^e TSINGHUA UNIVERSITY   (China)

Author keywords

Evolution; Histone methylation; Transcription elongation; Transcriptional output; Yeast

Indexed keywords

ALANINE; DNA; HISTONE H3; LYSINE; MESSENGER RNA; PROTEIN; TRANSCRIPTION ELONGATION FACTOR; TRANSCRIPTOME;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; CELL ELONGATION; CHROMATIN; CONTROLLED STUDY; EUKARYOTE EVOLUTION; FUNGAL GENETICS; GENE EXPRESSION; GENE LOCUS; GENETIC ANALYSIS; HISTONE METHYLATION; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN MODIFICATION; PROTEIN PROCESSING; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION;

CHROMATIN; DNA METHYLATION; EVOLUTION, MOLECULAR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; HISTONES; LYSINE; MODELS, MOLECULAR; MUTATION; NUCLEAR PROTEINS; PEPTIDE ELONGATION FACTORS; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

ASCOMYCOTA; SACCHAROMYCES CEREVISIAE;

EID: 79959667403     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.2050311     Document Type: Article

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