Development of a flexible strategy towards FR900482 and the mitomycins

Chemistry - A European Journal

Volumn 17, Issue 28, 2011, Pages 7890-7903

  Trost, Barry M ^a   O'Boyle, Brendan M ^b   Torres, Wildeliz ^c   Ameriks, Michael K ^d  

^a STANFORD UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^d JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

alkaloids; asymmetric catalysis; aziridine; mitomycin; natural products

Indexed keywords

ALKALOIDS; ASYMMETRIC CATALYSIS; AZIRIDINES; MITOMYCIN; NATURAL PRODUCTS;

AMINES; CATALYSIS; CELL CULTURE; CHEMICAL COMPOUNDS; DISEASES; METABOLITES; PALLADIUM COMPOUNDS; RHODIUM; RHODIUM COMPOUNDS;

IONIC LIQUIDS;

4 FORMYL 6,9 DIHYDROXY 14 OXA 1,11 DIAZATETRACYCLO[7.4.1.0 2,7 0 10,12]TETRADECA 2,4,6 TRIEN 8 YLMETHYLCARBAMATE; 7 EPI FR900482; 7-EPI-FR900482; ANTINEOPLASTIC AGENT; BIOLOGICAL PRODUCT; MITOMYCIN; OXAZINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; HUMAN; STEREOISOMERISM; SYNTHESIS;

ANTINEOPLASTIC AGENTS; BIOLOGICAL PRODUCTS; DRUG DESIGN; HUMANS; MITOMYCINS; MOLECULAR STRUCTURE; OXAZINES; STEREOISOMERISM;

EID: 79959661268     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201003489     Document Type: Article

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