메뉴 건너뛰기




Volumn 6, Issue 6, 2011, Pages

Tissue and serum microRNAs in the KrasG12D transgenic animal model and in patients with pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; GEMCITABINE; MICRORNA; PROTEIN MLH1; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; DRUG DERIVATIVE; KRAS2 PROTEIN, MOUSE; PROTEIN P21;

EID: 79959588396     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020687     Document Type: Article
Times cited : (80)

References (80)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 2
    • 60149084560 scopus 로고    scopus 로고
    • MicroRNAs and cancer: short RNAs go a long way
    • Ventura A, Jacks T, (2009) MicroRNAs and cancer: short RNAs go a long way. Cell 136: 586-591.
    • (2009) Cell , vol.136 , pp. 586-591
    • Ventura, A.1    Jacks, T.2
  • 3
    • 65349117527 scopus 로고    scopus 로고
    • MiRNAs and cancer
    • Visone R, Croce CM, (2009) MiRNAs and cancer. Am J Pathol 174: 1131-1138.
    • (2009) Am J Pathol , vol.174 , pp. 1131-1138
    • Visone, R.1    Croce, C.M.2
  • 5
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo C, Missiaglia E, Hagan JP, Falconi M, Capelli P, et al. (2006) MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 24: 4677-4684.
    • (2006) J Clin Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3    Falconi, M.4    Capelli, P.5
  • 6
    • 28144452515 scopus 로고    scopus 로고
    • Specialized DNA arrays for the differentiation of pancreatic tumors
    • Buchholz M, Kestler HA, Bauer A, Böck W, Rau B, et al. (2005) Specialized DNA arrays for the differentiation of pancreatic tumors. Clin Cancer Res 11: 8048-8054.
    • (2005) Clin Cancer Res , vol.11 , pp. 8048-8054
    • Buchholz, M.1    Kestler, H.A.2    Bauer, A.3    Böck, W.4    Rau, B.5
  • 7
    • 34247862190 scopus 로고    scopus 로고
    • MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
    • Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, et al. (2007) MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 297: 1901-1908.
    • (2007) JAMA , vol.297 , pp. 1901-1908
    • Bloomston, M.1    Frankel, W.L.2    Petrocca, F.3    Volinia, S.4    Alder, H.5
  • 8
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM, (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866.
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 10
    • 67449164586 scopus 로고    scopus 로고
    • MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor
    • Li J, Huang H, Sun L, Yang M, Pan C, et al. (2009) MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor. Clin Cancer Res 15: 3998-4008.
    • (2009) Clin Cancer Res , vol.15 , pp. 3998-4008
    • Li, J.1    Huang, H.2    Sun, L.3    Yang, M.4    Pan, C.5
  • 11
    • 38949111440 scopus 로고    scopus 로고
    • MicroRNAs as prognostic indicators and therapeutic targets: potential effect on breast cancer management
    • Lowery AJ, Miller N, McNeill RE, Kerin MJ, (2008) MicroRNAs as prognostic indicators and therapeutic targets: potential effect on breast cancer management. Clin Cancer Res 14: 360-365.
    • (2008) Clin Cancer Res , vol.14 , pp. 360-365
    • Lowery, A.J.1    Miller, N.2    McNeill, R.E.3    Kerin, M.J.4
  • 12
    • 73449134501 scopus 로고    scopus 로고
    • Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival
    • Greither T, Grochola LF, Udelnow A, Lautenschläger C, Würl P, et al. (2010) Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival. Int J Cancer 126: 73-80.
    • (2010) Int J Cancer , vol.126 , pp. 73-80
    • Greither, T.1    Grochola, L.F.2    Udelnow, A.3    Lautenschläger, C.4    Würl, P.5
  • 13
    • 57049090610 scopus 로고    scopus 로고
    • MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival
    • Dillhoff M, Liu J, Frankel W, Croce C, Bloomston M, (2008) MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival. J Gastrointest Surg 12: 2171-2176.
    • (2008) J Gastrointest Surg , vol.12 , pp. 2171-2176
    • Dillhoff, M.1    Liu, J.2    Frankel, W.3    Croce, C.4    Bloomston, M.5
  • 14
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu C-G, Ambs S, Cimmino A, et al. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.-G.3    Ambs, S.4    Cimmino, A.5
  • 15
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, et al. (2009) Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138: 592-603.
    • (2009) Cell , vol.138 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3    Lobo, N.4    Dalerba, P.5
  • 16
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska E, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.3    Alvarez-Saavedra, E.4    Lamb, J.5
  • 19
    • 67650520139 scopus 로고    scopus 로고
    • Detection of cancer with serum miRNAs on an oligonucleotide microarray
    • Lodes MJ, Caraballo M, Suciu D, Munro S, Kumar A, et al. (2009) Detection of cancer with serum miRNAs on an oligonucleotide microarray. PLoS ONE 4: e6229.
    • (2009) PLoS ONE , vol.4
    • Lodes, M.J.1    Caraballo, M.2    Suciu, D.3    Munro, S.4    Kumar, A.5
  • 20
    • 66049112674 scopus 로고    scopus 로고
    • Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening
    • Ng EKO, Chong WWS, Jin H, Lam EKY, Shin VY, et al. (2009) Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 58: 1375-1381.
    • (2009) Gut , vol.58 , pp. 1375-1381
    • Ng, E.K.O.1    Chong, W.W.S.2    Jin, H.3    Lam, E.K.Y.4    Shin, V.Y.5
  • 21
    • 77953192081 scopus 로고    scopus 로고
    • Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer
    • Huang Z, Huang D, Ni S, Peng Z, Sheng W, et al. (2010) Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer. Int J Cancer 127: 118-126.
    • (2010) Int J Cancer , vol.127 , pp. 118-126
    • Huang, Z.1    Huang, D.2    Ni, S.3    Peng, Z.4    Sheng, W.5
  • 23
  • 24
    • 77649138141 scopus 로고    scopus 로고
    • Circulating microRNAs as novel minimally invasive biomarkers for breast cancer
    • Heneghan HM, Miller N, Lowery AJ, Sweeney KJ, Newell J, et al. (2010) Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. Ann Surg 251: 499-505.
    • (2010) Ann Surg , vol.251 , pp. 499-505
    • Heneghan, H.M.1    Miller, N.2    Lowery, A.J.3    Sweeney, K.J.4    Newell, J.5
  • 25
    • 64149132942 scopus 로고    scopus 로고
    • MicroRNAs: novel biomarkers for human cancer
    • Bartels CL, Tsongalis GJ, (2009) MicroRNAs: novel biomarkers for human cancer. Clin Chem 55: 623-631.
    • (2009) Clin Chem , vol.55 , pp. 623-631
    • Bartels, C.L.1    Tsongalis, G.J.2
  • 27
    • 78549270354 scopus 로고    scopus 로고
    • Circulating microRNAs are new and sensitive biomarkers of myocardial infarction
    • D'Alessandra Y, Devanna P, Limana F, Straino S, Di Carlo A, et al. (2010) Circulating microRNAs are new and sensitive biomarkers of myocardial infarction. Eur Heart J 31: 2765-2773.
    • (2010) Eur Heart J , vol.31 , pp. 2765-2773
    • D'Alessandra, Y.1    Devanna, P.2    Limana, F.3    Straino, S.4    Di Carlo, A.5
  • 29
    • 77954161288 scopus 로고    scopus 로고
    • Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans
    • Wang G-K, Zhu J-Q, Zhang J-T, Li Q, Li Y, et al. (2010) Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur Heart J 31: 659-666.
    • (2010) Eur Heart J , vol.31 , pp. 659-666
    • Wang, G.-K.1    Zhu, J.-Q.2    Zhang, J.-T.3    Li, Q.4    Li, Y.5
  • 30
    • 72949112451 scopus 로고    scopus 로고
    • Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction
    • Ai J, Zhang R, Li Y, Pu J, Lu Y, et al. (2010) Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction. Biochem Biophys Res Commun 391: 73-77.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 73-77
    • Ai, J.1    Zhang, R.2    Li, Y.3    Pu, J.4    Lu, Y.5
  • 31
    • 77957259803 scopus 로고    scopus 로고
    • Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
    • Zampetaki A, Kiechl S, Drozdov I, Willeit P, Mayr U, et al. (2010) Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes. Circ Res 107: 810-817.
    • (2010) Circ Res , vol.107 , pp. 810-817
    • Zampetaki, A.1    Kiechl, S.2    Drozdov, I.3    Willeit, P.4    Mayr, U.5
  • 32
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • Jones S, Zhang X, Parsons DW, Lin JC-H, Leary RJ, et al. (2008) Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321: 1801-1806.
    • (2008) Science , vol.321 , pp. 1801-1806
    • Jones, S.1    Zhang, X.2    Parsons, D.W.3    Lin, J.C.-H.4    Leary, R.J.5
  • 35
    • 9144266295 scopus 로고    scopus 로고
    • Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
    • Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, et al. (2003) Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4: 437-450.
    • (2003) Cancer Cell , vol.4 , pp. 437-450
    • Hingorani, S.R.1    Petricoin, E.F.2    Maitra, A.3    Rajapakse, V.4    King, C.5
  • 36
    • 34248372925 scopus 로고    scopus 로고
    • The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia
    • Carrière C, Seeley ES, Goetze T, Longnecker DS, Korc M, (2007) The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proc Natl Acad Sci USA 104: 4437-4442.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4437-4442
    • Carrière, C.1    Seeley, E.S.2    Goetze, T.3    Longnecker, D.S.4    Korc, M.5
  • 37
    • 0346455774 scopus 로고    scopus 로고
    • Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
    • Aguirre AJ, Bardeesy N, Sinha M, Lopez L, Tuveson DA, et al. (2003) Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes & Development 17: 3112-3126.
    • (2003) Genes & Development , vol.17 , pp. 3112-3126
    • Aguirre, A.J.1    Bardeesy, N.2    Sinha, M.3    Lopez, L.4    Tuveson, D.A.5
  • 38
    • 19344362405 scopus 로고    scopus 로고
    • Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
    • Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, et al. (2005) Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7: 469-483.
    • (2005) Cancer Cell , vol.7 , pp. 469-483
    • Hingorani, S.R.1    Wang, L.2    Multani, A.S.3    Combs, C.4    Deramaudt, T.B.5
  • 39
    • 33645824724 scopus 로고    scopus 로고
    • Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse
    • Bardeesy N, Aguirre AJ, Chu GC, Cheng K-H, Lopez LV, et al. (2006) Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci USA 103: 5947-5952.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5947-5952
    • Bardeesy, N.1    Aguirre, A.J.2    Chu, G.C.3    Cheng, K.-H.4    Lopez, L.V.5
  • 40
    • 77957150824 scopus 로고    scopus 로고
    • KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
    • Morris JP, Wang SC, Hebrok M, (2010) KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. Nat Rev Cancer 10: 683-695.
    • (2010) Nat Rev Cancer , vol.10 , pp. 683-695
    • Morris, J.P.1    Wang, S.C.2    Hebrok, M.3
  • 41
    • 57449116846 scopus 로고    scopus 로고
    • MicroRNAs in pancreatic ductal adenocarcinoma: new diagnostic and therapeutic clues
    • Seux M, Iovanna J, Dagorn J-C, Dusetti NJ, (2009) MicroRNAs in pancreatic ductal adenocarcinoma: new diagnostic and therapeutic clues. Pancreatology 9: 66-72.
    • (2009) Pancreatology , vol.9 , pp. 66-72
    • Seux, M.1    Iovanna, J.2    Dagorn, J.-C.3    Dusetti, N.J.4
  • 42
    • 77949264996 scopus 로고    scopus 로고
    • Advanced pancreatic carcinoma: current treatment and future challenges
    • Stathis A, Moore MJ, Medscape, (2010) Advanced pancreatic carcinoma: current treatment and future challenges. Nat Rev Clin Oncol 7: 163-172.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 163-172
    • Stathis, A.1    Moore, M.J.2    Medscape3
  • 43
    • 33846813656 scopus 로고    scopus 로고
    • Expression profiling identifies microRNA signature in pancreatic cancer
    • Lee EJ, Gusev Y, Jiang J, Nuovo GJ, Lerner MR, et al. (2007) Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer 120: 1046-1054.
    • (2007) Int J Cancer , vol.120 , pp. 1046-1054
    • Lee, E.J.1    Gusev, Y.2    Jiang, J.3    Nuovo, G.J.4    Lerner, M.R.5
  • 44
    • 34248200155 scopus 로고    scopus 로고
    • MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma
    • Szafranska AE, Davison TS, John J, Cannon T, Sipos B, et al. (2007) MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 26: 4442-4452.
    • (2007) Oncogene , vol.26 , pp. 4442-4452
    • Szafranska, A.E.1    Davison, T.S.2    John, J.3    Cannon, T.4    Sipos, B.5
  • 46
    • 66649097288 scopus 로고    scopus 로고
    • A distinct role for secreted fibroblast growth factor-binding proteins in development
    • Gibby KA, McDonnell K, Schmidt MO, Wellstein A, (2009) A distinct role for secreted fibroblast growth factor-binding proteins in development. Proc Natl Acad Sci USA 106: 8585-8590.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8585-8590
    • Gibby, K.A.1    McDonnell, K.2    Schmidt, M.O.3    Wellstein, A.4
  • 47
    • 78649480507 scopus 로고    scopus 로고
    • miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development
    • Ucar A, Vafaizadeh V, Jarry H, Fiedler J, Klemmt PAB, et al. (2010) miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development. Nat Genet.
    • (2010) Nat Genet
    • Ucar, A.1    Vafaizadeh, V.2    Jarry, H.3    Fiedler, J.4    Klemmt, P.A.B.5
  • 48
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • Guo H, Ingolia NT, Weissman JS, Bartel DP, (2010) Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466: 835-840.
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 49
    • 33947254016 scopus 로고    scopus 로고
    • Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
    • Feldmann G, Dhara S, Fendrich V, Bedja D, Beaty R, et al. (2007) Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer Res 67: 2187-2196.
    • (2007) Cancer Res , vol.67 , pp. 2187-2196
    • Feldmann, G.1    Dhara, S.2    Fendrich, V.3    Bedja, D.4    Beaty, R.5
  • 50
    • 33744521896 scopus 로고    scopus 로고
    • Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
    • Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, et al. (2006) Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 130: 2113-2129.
    • (2006) Gastroenterology , vol.130 , pp. 2113-2129
    • Meng, F.1    Henson, R.2    Lang, M.3    Wehbe, H.4    Maheshwari, S.5
  • 52
    • 70449700281 scopus 로고    scopus 로고
    • MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease
    • Wang J, Chen J, Chang P, LeBlanc A, Li D, et al. (2009) MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease. Cancer Prevention Research 2: 807-813.
    • (2009) Cancer Prevention Research , vol.2 , pp. 807-813
    • Wang, J.1    Chen, J.2    Chang, P.3    LeBlanc, A.4    Li, D.5
  • 53
    • 34248204213 scopus 로고    scopus 로고
    • Precursor lesions of pancreatic cancer: molecular pathology and clinical implications
    • Singh M, Maitra A, (2007) Precursor lesions of pancreatic cancer: molecular pathology and clinical implications. Pancreatology 7: 9-19.
    • (2007) Pancreatology , vol.7 , pp. 9-19
    • Singh, M.1    Maitra, A.2
  • 54
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, et al. (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 9: 654-659.
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3    Sjöstrand, M.4    Lee, J.J.5
  • 55
    • 78149420582 scopus 로고    scopus 로고
    • Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line
    • Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, et al. (2010) Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line. PLoS ONE 5: e13247.
    • (2010) PLoS ONE , vol.5
    • Ohshima, K.1    Inoue, K.2    Fujiwara, A.3    Hatakeyama, K.4    Kanto, K.5
  • 56
    • 78149419143 scopus 로고    scopus 로고
    • Selective release of microRNA species from normal and malignant mammary epithelial cells
    • Pigati L, Yaddanapudi SCS, Iyengar R, Kim D-J, Hearn SA, et al. (2010) Selective release of microRNA species from normal and malignant mammary epithelial cells. PLoS ONE 5: e13515.
    • (2010) PLoS ONE , vol.5
    • Pigati, L.1    Yaddanapudi, S.C.S.2    Iyengar, R.3    Kim, D.-J.4    Hearn, S.A.5
  • 57
    • 34548284448 scopus 로고    scopus 로고
    • Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development
    • Kloosterman WP, Lagendijk AK, Ketting RF, Moulton JD, Plasterk RHA, (2007) Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biol 5: e203.
    • (2007) PLoS Biol , vol.5
    • Kloosterman, W.P.1    Lagendijk, A.K.2    Ketting, R.F.3    Moulton, J.D.4    Plasterk, R.H.A.5
  • 59
    • 9144270691 scopus 로고    scopus 로고
    • A pancreatic islet-specific microRNA regulates insulin secretion
    • Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, et al. (2004) A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432: 226-230.
    • (2004) Nature , vol.432 , pp. 226-230
    • Poy, M.N.1    Eliasson, L.2    Krutzfeldt, J.3    Kuwajima, S.4    Ma, X.5
  • 60
    • 42449086421 scopus 로고    scopus 로고
    • miR-148 targets human DNMT3b protein coding region
    • Duursma AM, Kedde M, Schrier M, le Sage C, Agami R, (2008) miR-148 targets human DNMT3b protein coding region. RNA 14: 872-877.
    • (2008) RNA , vol.14 , pp. 872-877
    • Duursma, A.M.1    Kedde, M.2    Schrier, M.3    le Sage, C.4    Agami, R.5
  • 62
    • 0035300547 scopus 로고    scopus 로고
    • Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability
    • Yamamoto H, Itoh F, Nakamura H, Fukushima H, Sasaki S, et al. (2001) Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability. Cancer Res 61: 3139-3144.
    • (2001) Cancer Res , vol.61 , pp. 3139-3144
    • Yamamoto, H.1    Itoh, F.2    Nakamura, H.3    Fukushima, H.4    Sasaki, S.5
  • 63
    • 36649025655 scopus 로고    scopus 로고
    • OncomiRs: the discovery and progress of microRNAs in cancers
    • Cho WCS, (2007) OncomiRs: the discovery and progress of microRNAs in cancers. Mol Cancer 6: 60.
    • (2007) Mol Cancer , vol.6 , pp. 60
    • Cho, W.C.S.1
  • 65
    • 77952918274 scopus 로고    scopus 로고
    • Genetic variation in microRNA networks: the implications for cancer research
    • Ryan BM, Robles AI, Harris CC, (2010) Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 10: 389-402.
    • (2010) Nat Rev Cancer , vol.10 , pp. 389-402
    • Ryan, B.M.1    Robles, A.I.2    Harris, C.C.3
  • 66
    • 33847419143 scopus 로고    scopus 로고
    • Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice
    • Guerra C, Schuhmacher A, Canamero M, Grippo P, Verdaguer L, et al. (2007) Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice. Cancer Cell 11: 291-302.
    • (2007) Cancer Cell , vol.11 , pp. 291-302
    • Guerra, C.1    Schuhmacher, A.2    Canamero, M.3    Grippo, P.4    Verdaguer, L.5
  • 67
    • 33646083021 scopus 로고    scopus 로고
    • A rapid, simple, and humane method for submandibular bleeding of mice using a lancet
    • Golde W, Gollobin P, Rodriguez L, (2005) A rapid, simple, and humane method for submandibular bleeding of mice using a lancet. Lab Anim (NY) 34: 39-43.
    • (2005) Lab Anim (NY) , vol.34 , pp. 39-43
    • Golde, W.1    Gollobin, P.2    Rodriguez, L.3
  • 68
    • 33745612095 scopus 로고    scopus 로고
    • Pvclust: an R package for assessing the uncertainty in hierarchical clustering
    • Suzuki R, Shimodaira H, (2006) Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 22: 1540-1542.
    • (2006) Bioinformatics , vol.22 , pp. 1540-1542
    • Suzuki, R.1    Shimodaira, H.2
  • 69
    • 21644440363 scopus 로고    scopus 로고
    • Approximately unbiased tests of regions using multistep-multiscale bootstrap resampling
    • Shimodaira H, (2004) Approximately unbiased tests of regions using multistep-multiscale bootstrap resampling. Annals of Statistics 32: 2616-2641.
    • (2004) Annals of Statistics , vol.32 , pp. 2616-2641
    • Shimodaira, H.1
  • 70
    • 0035478854 scopus 로고    scopus 로고
    • Random Forests
    • Breiman L, (2001) Random Forests. Machine Learning 45: 5-32.
    • (2001) Machine Learning , vol.45 , pp. 5-32
    • Breiman, L.1
  • 71
    • 9144241047 scopus 로고    scopus 로고
    • Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies
    • Iacobuzio-Donahue CA, Ashfaq R, Maitra A, Adsay NV, Shen-Ong GL, et al. (2003) Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. Cancer Res 63: 8614-8622.
    • (2003) Cancer Res , vol.63 , pp. 8614-8622
    • Iacobuzio-Donahue, C.A.1    Ashfaq, R.2    Maitra, A.3    Adsay, N.V.4    Shen-Ong, G.L.5
  • 72
    • 0038179900 scopus 로고    scopus 로고
    • Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
    • Logsdon CD, Simeone DM, Binkley C, Arumugam T, Greenson JK, et al. (2003) Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res 63: 2649-2657.
    • (2003) Cancer Res , vol.63 , pp. 2649-2657
    • Logsdon, C.D.1    Simeone, D.M.2    Binkley, C.3    Arumugam, T.4    Greenson, J.K.5
  • 73
    • 27144454969 scopus 로고    scopus 로고
    • Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions
    • Buchholz M, Braun M, Heidenblut A, Kestler H, Klöppel G, et al. (2005) Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions. Oncogene 24: 6626-6636.
    • (2005) Oncogene , vol.24 , pp. 6626-6636
    • Buchholz, M.1    Braun, M.2    Heidenblut, A.3    Kestler, H.4    Klöppel, G.5
  • 74
  • 75
    • 33846813656 scopus 로고    scopus 로고
    • Expression profiling identifies microRNA signature in pancreatic cancer
    • Lee EJ, Gusev Y, Jiang J, Nuovo GJ, Lerner MR, et al. (2007) Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer 120: 1046-1054.
    • (2007) Int J Cancer , vol.120 , pp. 1046-1054
    • Lee, E.J.1    Gusev, Y.2    Jiang, J.3    Nuovo, G.J.4    Lerner, M.R.5
  • 76
    • 34247862190 scopus 로고    scopus 로고
    • MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
    • Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, et al. (2007) MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 297: 1901-1908.
    • (2007) JAMA , vol.297 , pp. 1901-1908
    • Bloomston, M.1    Frankel, W.L.2    Petrocca, F.3    Volinia, S.4    Alder, H.5
  • 78
    • 34248200155 scopus 로고    scopus 로고
    • MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma
    • Szafranska AE, Davison TS, John J, Cannon T, Sipos B, et al. (2007) MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 26: 4442-4452.
    • (2007) Oncogene , vol.26 , pp. 4442-4452
    • Szafranska, A.E.1    Davison, T.S.2    John, J.3    Cannon, T.4    Sipos, B.5
  • 79
    • 0038179900 scopus 로고    scopus 로고
    • Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
    • Logsdon CD, Simeone DM, Binkley C, Arumugam T, Greenson JK, et al. (2003) Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res 63: 2649-2657.
    • (2003) Cancer Res , vol.63 , pp. 2649-2657
    • Logsdon, C.D.1    Simeone, D.M.2    Binkley, C.3    Arumugam, T.4    Greenson, J.K.5
  • 80
    • 27144454969 scopus 로고    scopus 로고
    • Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions
    • Buchholz M, Braun M, Heidenblut A, Kestler HA, Klöppel G, et al. (2005) Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions. Oncogene 24: 6626-6636.
    • (2005) Oncogene , vol.24 , pp. 6626-6636
    • Buchholz, M.1    Braun, M.2    Heidenblut, A.3    Kestler, H.A.4    Klöppel, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.