Imaging of branched chain amino acid metabolism in tumors with hyperpolarized13C ketoisocaproate

International Journal of Cancer

Volumn 127, Issue 3, 2010, Pages 729-736

  Karlsson, Magnus ^a   Jensen, Pernille R ^a   In't Zandt, René ^a   Gisselsson, Anna ^a   Hansson, Georg ^a   Duus, Jens Ø ^b   Meier, Sebastian ^b   Lerche, Mathilde H ^a  

^a Imagnia AB   (Sweden)

^b CARLSBERG LABORATORY   (Denmark)

Author keywords

13C NMR; A ketoisocaproate; BCAT; DNP NMR; Leucine

Indexed keywords

2 OXOISOCAPROIC ACID; 2 OXOISOCAPROIC ACID C 13; AMINOTRANSFERASE; BRANCHED CHAIN AMINO ACID TRANSAMINASE; LEUCINE; RADIOPHARMACEUTICAL AGENT; TUMOR MARKER; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST ADENOCARCINOMA; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG METABOLISM; DRUG STRUCTURE; DRUG UPTAKE; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; HYPERPOLARIZATION; IN VIVO STUDY; LYMPHOMA; METASTASIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONCOGENE MYC; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; UPREGULATION;

ADENOCARCINOMA; AMINO ACIDS; ANIMALS; BIOCATALYSIS; CARBON ISOTOPES; CELL LINE, TUMOR; FEMALE; KETO ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; RATS; RATS, INBRED LEW; TRANSAMINASES;

EID: 77954450961     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25072     Document Type: Article

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