Selective role for tumor necrosis factor-α, but not interleukin-1 or Kupffer cells, in down-regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen

Biochemical Pharmacology

Volumn 82, Issue 3, 2011, Pages 312-321

  Kinloch, Ryan D ^a   Lee, Choon Myung ^a   Van Rooijen, Nico ^b   Morgan, Edward T ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cytochrome P450; Inflammation; Interleukin 1; Kupffer cells; TNF

Indexed keywords

CLODRONIC ACID; CYTOCHROME P450; CYTOCHROME P450 2D9; CYTOCHROME P450 3A11; CYTOCHROME P450 3A25; CYTOCHROME P450 4A; CYTOCHROME P450 4F18; FLAVIN MONOOXYGENASE 3; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CELL COUNT; CITROBACTER RODENTIUM; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME REGULATION; FEMALE; GENE EXPRESSION REGULATION; KNOCKOUT MOUSE; KUPFFER CELL; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE;

ANIMALS; CITROBACTER RODENTIUM; CYTOCHROME P-450 CYP3A; DOWN-REGULATION; ENTEROBACTERIACEAE INFECTIONS; INTERLEUKIN-1; INTESTINAL DISEASES; KUPFFER CELLS; LIVER; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RNA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79959552379     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.04.016     Document Type: Article

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