Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH

Acta Crystallographica Section D: Biological Crystallography

Volumn 67, Issue 7, 2011, Pages 639-645

  Kim, Sung Eun ^a   Bahta, Medhanit ^a   Lountos, George T ^a   Ulrich, Robert G ^b   Burke, Terrence R ^a   Waugh, David S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

isothiazolidinone; protein tyrosine phosphatases; Yersinia pestis; YopH

Indexed keywords

BIOMIMETIC MATERIAL; ISOTHIAZOLIDINONE; OUTER MEMBRANE PROTEIN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE; THIAZOLE DERIVATIVE; YOPH PROTEIN, YERSINIA;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; PHOSPHORYLATION; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; YERSINIA PESTIS;

BACTERIAL OUTER MEMBRANE PROTEINS; BIOMIMETIC MATERIALS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN KINASE INHIBITORS; PROTEIN TYROSINE PHOSPHATASES; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; YERSINIA PESTIS;

YERSINIA PESTIS;

EID: 79959551793     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444911018610     Document Type: Article

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