The metabotropic glutamate receptor 7 allosteric modulator AMN082: A monoaminergic agent in disguise?

Journal of Pharmacology and Experimental Therapeutics

Volumn 338, Issue 1, 2011, Pages 345-352

  Sukoff Rizzo, Stacey J ^a   Leonard, Sarah K ^a   Gilbert, Adam ^a   Dollings, Paul ^a   Smith, Deborah L ^a   Zhang, Mei Yi ^a   Di, Li ^a   Platt, Brian J ^a   Neal, Sarah ^a   Dwyer, Jason M ^a   Bender, Corey N ^a   Zhang, Jean ^a   Lock, Tim ^a   Kowal, Dianne ^a   Kramer, Angela ^a   Randall, Andrew ^a   Huselton, Christine ^a   Vishwanathan, Karthick ^a   Tse, Susanna Y ^a   Butera, John ^a   Ring, Robert H ^a   Rosenzweig Lipson, Sharon ^a   Hughes, Zoë A ^a   Dunlop, John ^a   more..

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMN 082; DOPAMINE TRANSPORTER; DRUG METABOLITE; FLUOXETINE; METABOTROPIC RECEPTOR 7; METABOTROPIC RECEPTOR AGONIST; N BENZHYDRYLETHANE 1,2 DIAMINE; N,N' DIBENZHYDRYLETHANE 1,2 DIAMINE; NORADRENALIN TRANSPORTER; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DEPRESSION; DOSE RESPONSE; DRUG BINDING; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG MECHANISM; DRUG METABOLISM; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE;

ALLOSTERIC REGULATION; ANIMALS; BENZHYDRYL COMPOUNDS; BIOGENIC MONOAMINES; CHO CELLS; CRICETINAE; CRICETULUS; HEK293 CELLS; HUMANS; MALE; MICE; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 79959527317     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.177378     Document Type: Article

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