The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat

Behavioural Pharmacology

Volumn 20, Issue 7, 2009, Pages 596-604

  Dolan, Sharron ^a   Gunn, Mark D ^c   Biddlestone, Laura ^d   Nolan, Andrea M ^b  

^a GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c HERIOT WATT UNIVERSITY   (United Kingdom)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

AMN082; Carrageenan; Mechanical allodynia; Metabotropic glutamate receptor 7; Paw incision; Rat; Thermal hyperalgesia

Indexed keywords

AMN 082; ANALGESIC AGENT; CARRAGEENAN; DICLOFENAC; METABOTROPIC RECEPTOR 7; METABOTROPIC RECEPTOR AGONIST; N,N' DIBENZHYDRYLETHANE 1,2 DIAMINE; UNCLASSIFIED DRUG;

ALLODYNIA; ALLOSTERISM; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; HYPERALGESIA; INCISION; INFLAMMATION; MALE; MECHANICAL STIMULATION; NOCICEPTIVE STIMULATION; NONHUMAN; RAT; SYSTEMIC THERAPY; THERMAL STIMULATION;

ALLOSTERIC REGULATION; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZHYDRYL COMPOUNDS; CARRAGEENAN; DICLOFENAC; DISEASE MODELS, ANIMAL; HYPERALGESIA; INFLAMMATION; INJECTIONS, INTRADERMAL; INJECTIONS, SPINAL; MALE; PAIN; PAIN, POSTOPERATIVE; PHOSPHOSERINE; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 70349671771     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32832ec5d1     Document Type: Article

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