메뉴 건너뛰기




Volumn 34, Issue 1, 2009, Pages 55-65

Nanocrystal technology for oral delivery of poorly water-soluble drugs

Author keywords

Bioavailability; Dissolution rate; Nanocrystal; Nanotechnology; Particle size

Indexed keywords

NANOCRYSTAL; RAPAMYCIN; WATER;

EID: 79959450158     PISSN: 13004182     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (48)

References (50)
  • 2
    • 55749100987 scopus 로고    scopus 로고
    • Nanotechnology and Nanomaterials: Promises for Improved Tissue Regeneration
    • Zhang L, Webster TJ. Nanotechnology and Nanomaterials: Promises for Improved Tissue Regeneration. Nano Today 4: 66-80, 2009.
    • (2009) Nano Today , vol.4 , pp. 66-80
    • Zhang, L.1    Webster, T.J.2
  • 3
    • 33750633978 scopus 로고    scopus 로고
    • Nanomedicine: An unresolved regulatory issue
    • DOI 10.1016/j.yrtph.2006.04.009, PII S0273230006000821
    • Chan VSW. Nanomedicine: An Unresolved Regulatory Issue. Regul Toxicol Pharmacol 46: 218-224, 2006. (Pubitemid 44692901)
    • (2006) Regulatory Toxicology and Pharmacology , vol.46 , Issue.3 , pp. 218-224
    • Chan, V.S.W.1
  • 4
    • 28444461830 scopus 로고    scopus 로고
    • Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation
    • DOI 10.1016/j.ejpb.2005.05.009, PII S0939641105001797
    • Keck CM, Müller RH. Drug Nanocrystals of Poorly Soluble Drugs Produced by High Pressure Homogenisation. Eur J Pharm and Biopharm 62: 3-16, 2006. (Pubitemid 41736019)
    • (2006) European Journal of Pharmaceutics and Biopharmaceutics , vol.62 , Issue.1 , pp. 3-16
    • Keck, C.M.1    Muller, R.H.2
  • 6
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • DOI 10.1016/S0169-409X(00)00129-0, PII S0169409X00001290
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 46(1-3):3-26, 2001. (Pubitemid 33653411)
    • (2000) Advanced Drug Delivery Reviews , vol.46 , Issue.1-3 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 7
    • 0028948839 scopus 로고
    • A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
    • Amidon GL, Lennernäs H, Shah VP, Crison JR. A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of In Vitro Drug Product Dissolution and In Vivo Bioavailability. Pharm Res 12: 413-420, 1995.
    • (1995) Pharm Res , vol.12 , pp. 413-420
    • Amidon, G.L.1    Lennernäs, H.2    Shah, V.P.3    Crison, J.R.4
  • 8
    • 33846783997 scopus 로고    scopus 로고
    • Turbidimetric measurement and prediction of dissolution rates of poorly soluble drug nanocrystals
    • DOI 10.1016/j.jconrel.2006.11.011, PII S0168365906006468
    • Crisp MT, Tucker CJ, Rogers TL, Williams RO, Johnston KP. Turbidimetric Measurement and Prediction of Dissolution Rates of Poorly Soluble Drug Nanocrystals. J Control Release 117: 351-359, 2007. (Pubitemid 46216578)
    • (2007) Journal of Controlled Release , vol.117 , Issue.3 , pp. 351-359
    • Crisp, M.T.1    Tucker, C.J.2    Rogers, T.L.3    Williams III, R.O.4    Johnston, K.P.5
  • 11
    • 0034002261 scopus 로고    scopus 로고
    • Role of the development scientist in compound lead selection and optimization
    • DOI 10.1002/(SICI)1520-6017(200002)89:2<145::AID-JPS2>3.0.CO;2-6
    • Venkatesh, S, Lipper RA. Role of the Development Scientist in Compound Lead Selection and Optimization. J Pharm Sci 89: 145-154, 2000. (Pubitemid 30120795)
    • (2000) Journal of Pharmaceutical Sciences , vol.89 , Issue.2 , pp. 145-154
    • Venkatesh, S.1    Lipper, R.A.2
  • 13
    • 0034601240 scopus 로고    scopus 로고
    • Improving drug solubility for oral delivery using solid dispersions
    • DOI 10.1016/S0939-6411(00)00076-X, PII S093964110000076X
    • Leuner C, Dressman J. Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm and Biopharm 50: 47-60, 2000. (Pubitemid 30326688)
    • (2000) European Journal of Pharmaceutics and Biopharmaceutics , vol.50 , Issue.1 , pp. 47-60
    • Leuner, C.1    Dressman, J.2
  • 14
    • 0037373357 scopus 로고    scopus 로고
    • Properties of rapidly dissolving eutectic mixtures of poly(ethylene glycol) and fenofibrate: The eutectic microstructure
    • DOI 10.1002/jps.10324
    • Law D, Wang W, Schmitt AE, Qiu Y, Krill SL, Fort JJ. Properties of Rapidly Dissolving Eutectic Mixtures of Poly(ethylene glycol) and Fenofibrate: The Eutectic Microstructure. J Pharm Sci 92: 505-515, 2003. (Pubitemid 36258965)
    • (2003) Journal of Pharmaceutical Sciences , vol.92 , Issue.3 , pp. 505-515
    • Law, D.1    Wang, W.2    Schmitt, E.A.3    Qiu, Y.4    Krill, S.L.5    Fort, J.J.6
  • 15
    • 0032885450 scopus 로고    scopus 로고
    • Solid Dispersion of Poorly Water-Soluble Drugs: Early Promises, Subsequent Problems, and Recent Breakthroughs
    • Serajuddin ATM. Solid Dispersion of Poorly Water-Soluble Drugs: Early Promises, Subsequent Problems, and Recent Breakthroughs. J Pharm Sci 88: 1058-1066, 1999.
    • (1999) J Pharm Sci , vol.88 , pp. 1058-1066
    • Serajuddin, A.T.M.1
  • 17
    • 79959415480 scopus 로고    scopus 로고
    • Farmasötik Teknoloji Temel Konular ve Dozaj Şekilleri
    • st ed. İstanbul: Kontrollü Salim Sistemleri Derneǧi; Piksel Bilişim ve Matbaacilik Reklamcilik ve Filmcilik hizmetleri Ltd. Şti.Press;
    • st ed. İstanbul: Kontrollü Salim Sistemleri Derneǧi; Piksel Bilişim ve Matbaacilik Reklamcilik ve Filmcilik hizmetleri Ltd. Şti.Press; 2004. p. 85-96.
    • (2004) Çözünürlük Ve Çözünme Hizina Etki Eden Faktörler , pp. 85-96
    • Çapan, Y.1
  • 20
    • 33645276807 scopus 로고    scopus 로고
    • Experimental determination of the diffusion boundary layer width of micron and submicron particles
    • Galli C. Experimental determination of the diffusion boundary layer width of micron and submicron particles. Int J Pharm 313: 114-122, 2006.
    • (2006) Int J Pharm , vol.313 , pp. 114-122
    • Galli, C.1
  • 21
    • 70349332606 scopus 로고    scopus 로고
    • Nanoparticulate megestrol formulations
    • Elan Pharma International Limited, assignee. US patent 7,101,576. September 5
    • Hovey D, Pruiit J, Ryde T, inventors; Elan Pharma International Limited, assignee. Nanoparticulate megestrol formulations. US patent 7,101,576. 2006 September 5.
    • (2006)
    • Hovey, D.1    Pruiit, J.2    Ryde, T.3
  • 22
    • 79959385213 scopus 로고    scopus 로고
    • Nanoparticulate candesartan formulations
    • Elan Pharma International Limited, assignee. WO 074218. July 13
    • Liversidge G, Jenkins S, inventors; Elan Pharma International Limited, assignee. Nanoparticulate candesartan formulations. WO 074218. 2006 July 13.
    • (2006)
    • Liversidge, G.1    Jenkins, S.2
  • 23
    • 79959384078 scopus 로고    scopus 로고
    • Solid dose nanoparticulate compositions
    • Elan Pharma International Limited, assignee. WO 666,539. March 28
    • Ruddy SB, Ryde NP, inventors; Elan Pharma International Limited, assignee. Solid dose nanoparticulate compositions. WO 666,539. 2002 March 28.
    • (2002)
    • Ruddy, S.B.1    Ryde, N.P.2
  • 24
    • 69749103682 scopus 로고    scopus 로고
    • Nanocrystal technology, drug delivery and clinical applications
    • Junghanns JUAH, Müller AH. Nanocrystal technology, drug delivery and clinical applications. Int J Nanomedicine 3(3):295-309, 2008.
    • (2008) Int J Nanomedicine , vol.3 , Issue.3 , pp. 295-309
    • Junghanns, J.U.A.H.1    Müller, A.H.2
  • 25
    • 4544275025 scopus 로고    scopus 로고
    • Challenges and solutions for the delivery of biotech drugs - A review of drug nanocrystal technology and lipid nanoparticles
    • DOI 10.1016/j.jbiotec.2004.06.007, PII S0168165604003128
    • Müller RH, Keck CM. Challenges and Solutions for the Delivery of Biotech Drugs: a Review of Drug Nanocrystal Technology and Lipid Nanoparticles. J Biotech 113: 151-170, 2004. (Pubitemid 39237077)
    • (2004) Journal of Biotechnology , vol.113 , Issue.1-3 , pp. 151-170
    • Muller, R.H.1    Keck, C.M.2
  • 26
    • 4644309307 scopus 로고    scopus 로고
    • Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology
    • DOI 10.1016/j.ejpb.2004.03.022, PII S0939641104000852
    • Möschwitzera JM, Achleitner G, Pomper H, Müller RH. Development of an Intravenously Injectable Chemically Stable Aqueous Omeprazole Formulation Using Nanosuspension Technology. Eur J Pharm and Biopharm 58: 615-619, 2004. (Pubitemid 39297108)
    • (2004) European Journal of Pharmaceutics and Biopharmaceutics , vol.58 , Issue.3 , pp. 615-619
    • Moschwitzer, J.1    Achleitner, G.2    Pomper, H.3    Muller, R.H.4
  • 27
    • 0242694524 scopus 로고    scopus 로고
    • NanoCrystal Technology Targets Poorly Water-Soluble Drugs
    • Coppola D. Nanocrystal Technology Targets Poorly Water-soluble Drugs. Pharm Tech 27: 20, 2003. (Pubitemid 37392672)
    • (2003) Pharmaceutical Technology , vol.27 , Issue.11 , pp. 20
    • Coppola, D.1
  • 29
    • 43449094630 scopus 로고    scopus 로고
    • A Novel Bottom-Up Process to Produce Drug Nanocrystals: Controlled Crystallization during Freeze-Drying
    • Waard H, Hinrichs WLJ, Frijlink HW. A Novel Bottom-Up Process to Produce Drug Nanocrystals: Controlled Crystallization During Freeze-Drying. J Control Release 128: 179-183, 2008.
    • (2008) J Control Release , vol.128 , pp. 179-183
    • Waard, H.1    Hinrichs, W.L.J.2    Frijlink, H.W.3
  • 30
    • 34548049483 scopus 로고    scopus 로고
    • Nanosizing - Oral formulation development and biopharmaceutical evaluation
    • DOI 10.1016/j.addr.2007.05.003, PII S0169409X0700083X
    • Kesisoglou F, Panmai S, Wu Y. Nanosizing - Oral formulation development and biopharmaceutical evaluation. Adv Drug Deliv Rev 59: 631-644, 2007. (Pubitemid 47285408)
    • (2007) Advanced Drug Delivery Reviews , vol.59 , Issue.7 , pp. 631-644
    • Kesisoglou, F.1    Panmai, S.2    Wu, Y.3
  • 31
    • 4544383493 scopus 로고    scopus 로고
    • Nanosuspensions in drug delivery
    • DOI 10.1038/nrd1494
    • Rabinow BE. Nanosuspensions in drug delivery. Nat Rev Drug Discov 3(9):785-796, 2004. (Pubitemid 39242830)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.9 , pp. 785-796
    • Rabinow, B.E.1
  • 33
    • 0028824401 scopus 로고
    • Drug Particle Size Reduction for Decreasing Gastric Irritancy and Enhancing Absorption of Naproxen in Rats
    • Liversidge GG, Conzentino P. Drug Particle Size Reduction for Decreasing Gastric Irritancy and Enhancing Absorption of Naproxen in Rats. Int J Pharm 125: 309-313, 1995.
    • (1995) Int J Pharm , vol.125 , pp. 309-313
    • Liversidge, G.G.1    Conzentino, P.2
  • 34
    • 77955049530 scopus 로고    scopus 로고
    • Nanonization strategies for poorly water-soluble drugs
    • 00: 00
    • Chen H, Khemtong C, Yang X, Chang X, Gao J. Nanonization strategies for poorly water-soluble drugs. DDT 00: 00, 2010.
    • (2010) DDT
    • Chen, H.1    Khemtong, C.2    Yang, X.3    Chang, X.4    Gao, J.5
  • 35
    • 42549152846 scopus 로고    scopus 로고
    • Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system
    • Gao L, Zhang D, Chen M. Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system. J Nanopart Res 10:845-862, 2008.
    • (2008) J Nanopart Res , vol.10 , pp. 845-862
    • Gao, L.1    Zhang, D.2    Chen, M.3
  • 36
    • 77953408726 scopus 로고    scopus 로고
    • Drug Nanocrystals: A Novel Formulation Approach for Poorly Soluble Drugs
    • P
    • Suman K, V S R Chandrasekhar P, Balaji S. Drug Nanocrystals: A Novel Formulation Approach for Poorly Soluble Drugs. Int J PharmTech Res 1(3):682-694, 2009.
    • (2009) Int J PharmTech Res , vol.1 , Issue.3 , pp. 682-694
    • Suman, K.1    Chandrasekhar, V.S.R.2    Balaji, S.3
  • 37
    • 0032842991 scopus 로고    scopus 로고
    • Effect of grinding with hydroxypropyl cellulose on the dissolution and particle size of a poorly water-soluble drug
    • Yamada T, Saito N, Imai T, Otagiri M. Effect of Grinding with Hydroxypropyl Cellulose on the Dissolution and Particle Size of a Poorly Water-Soluble Drug. Chem Pharm Bull 47: 1311-1313, 1999. (Pubitemid 29484889)
    • (1999) Chemical and Pharmaceutical Bulletin , vol.47 , Issue.9 , pp. 1311-1313
    • Yamada, T.1    Saito, N.2    Imai, T.3    Otagiri, M.4
  • 40
    • 34447646495 scopus 로고    scopus 로고
    • Developing early formulations: Practice and perspective
    • DOI 10.1016/j.ijpharm.2007.05.049, PII S0378517307004553
    • Li P, Zhao L. Developing early formulations: Practice and perspective. Int J Pharm 341: 1-19, 2007. (Pubitemid 47088122)
    • (2007) International Journal of Pharmaceutics , vol.341 , Issue.1-2 , pp. 1-19
    • Li, P.1    Zhao, L.2
  • 41
    • 0036806561 scopus 로고    scopus 로고
    • Comparative physicochemical properties of hydrocortisone-PVP composites prepared using supercritical carbon dioxide by the GAS anti-solvent recrystallization process, by coprecipitation and by spray drying
    • DOI 10.1016/S0378-5173(02)00326-5, PII S0378517302003265
    • Corrigan OI, Crean AM. Comparative Physicochemical Properties of Hydrocortisone / PVP Composites Prepared Using Supercritical Carbon Dioxide by the GAS Anti-Solvent Recrystallization Process, by Coprecipitation and by Spray Drying. Int J Pharm 245: 75-82, 2002. (Pubitemid 35299893)
    • (2002) International Journal of Pharmaceutics , vol.245 , Issue.1-2 , pp. 75-82
    • Corrigan, O.I.1    Crean, A.M.2
  • 42
    • 23844515061 scopus 로고    scopus 로고
    • Bioavailability enhancement of a COX-2 inhibitor, BMS-347070, from a nanocrystalline dispersion prepared by spray-drying
    • DOI 10.1002/jps.20366
    • Yin SX, Franchini M, Chen J, Hsieh A, Jen S, Lee T, Hussain M, Smith R. Bioavailability Enhancement of a COX-2 Inhibitor, BMS-347070, from a Nanocrystalline Dispersion Prepared by Spray-Drying. J Pharm Sci 94: 1598-1607, 2005. (Pubitemid 41168688)
    • (2005) Journal of Pharmaceutical Sciences , vol.94 , Issue.7 , pp. 1598-1607
    • Yin, S.X.1    Franchini, M.2    Chen, J.3    Hsieh, A.4    Jen, S.5    Lee, T.6    Hussain, M.7    Smith, R.8
  • 43
  • 44
    • 76849108225 scopus 로고    scopus 로고
    • Pure drug and polymer based nanotechnologies for the improved solubility, stability, bioavailability and targeting of anti-HIV drugs
    • Sharma P, Garg S. Pure drug and polymer based nanotechnologies for the improved solubility, stability, bioavailability and targeting of anti-HIV drugs. Adv Drug Deliv Rev 62:491-502, 2010.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 491-502
    • Sharma, P.1    Garg, S.2
  • 45
    • 19144364655 scopus 로고    scopus 로고
    • Role of polymeric stabilizers for drug nanocrystal dispersions
    • DOI 10.1016/j.cap.2005.01.012, PII S1567173905000180
    • Choi JY, Yoo JY, Kwak HS, Uk Nam B, Lee J. Role of Polymeric Stabilizers for Drug Nanocrystal Dispersions. Curr Appl Phys 5: 472-474, 2005. (Pubitemid 40714976)
    • (2005) Current Applied Physics , vol.5 , Issue.5 , pp. 472-474
    • Choi, J.-Y.1    Yoo, J.Y.2    Kwak, H.-S.3    Nam, B.U.4    Lee, J.5
  • 46
    • 61349095957 scopus 로고    scopus 로고
    • Development of an oral rutin nanocrystal formulation
    • Mauludin R, Müller RH, Keck CM. Development of an oral rutin nanocrystal formulation. Int J Pharm 370: 202-209, 2009.
    • (2009) Int J Pharm , vol.370 , pp. 202-209
    • Mauludin, R.1    Müller, R.H.2    Keck, C.M.3
  • 47
    • 59349119908 scopus 로고    scopus 로고
    • Kinetic solubility and dissolution velocity of rutin nanocrystals
    • Mauludin R, Müller RH, Keck CM. Kinetic solubility and dissolution velocity of rutin nanocrystals. Eur J Pharm and Biopharm 36 (4-5): 502-510, 2009.
    • (2009) Eur J Pharm and Biopharm , vol.36 , Issue.4-5 , pp. 502-510
    • Mauludin, R.1    Müller, R.H.2    Keck, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.