The mammary gland microenvironment directs progenitor cell fate in vivo

International Journal of Cell Biology

Volumn , Issue , 2011, Pages

  Smith, Gilbert H ^a   Bussard, Karen M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIREGULIN; BETA CATENIN; BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; INTERLEUKIN 6; NOTCH RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; PROGESTERONE; PROGESTERONE RECEPTOR; SOMATOMEDIN B; SOMATOMEDIN C; SONIC HEDGEHOG PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; WNT3A PROTEIN;

BREAST CANCER; BREAST CARCINOGENESIS; BREAST CELL; BREAST DEVELOPMENT; BREAST DUCT; BREAST EPITHELIUM; CANCER STEM CELL; CELL DIFFERENTIATION; CELL DIVISION; CELL FATE; CELL ULTRASTRUCTURE; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; IN VIVO STUDY; INTRACELLULAR SIGNALING; MAMMARY GLAND; MILK PRODUCTION; NONHUMAN; PRIORITY JOURNAL; PROGENY; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; STEM CELL NICHE; TISSUE REGENERATION; TUMOR MICROENVIRONMENT;

MUS;

EID: 79959381938     PISSN: 16878876     EISSN: 16878884     Source Type: Journal    
DOI: 10.1155/2011/451676     Document Type: Review

References (91)

1. Maximow A. A., The lymphocyte as a stem cell, common to different blood elements in embryonic development and during the post-fetal life of mammals Folia Haematologica 1909 8 123 134
2. Becker A. J., McCulloch E. A., Till J. E., Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells Nature 1963 197 4866 452 454
3. Martin G. R., Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells Proceedings of the National Academy of Sciences of the United States of America 1981 78 12 7634 7638 (Pubitemid 12186197)
4. Evans M. J., Kaufman M. H., Establishment in culture of pluripotential cells from mouse embryos Nature 1981 292 5819 154 156 (Pubitemid 11050741)
5. Schofield R., The relationship between the spleen colony-forming cell and the haemopoietic stem cell. A hypothesis Blood Cells 1978 4 1-2 7 25 (Pubitemid 8376317)
6. Scadden D. T., The stem-cell niche as an entity of action Nature 2006 441 7097 1075 1079 (Pubitemid 43990719)
7. Bissell M. J., The differentiated state of normal and malignant cells or how to define a normal cell in culture International Review of Cytology 1981 70 27 100 (Pubitemid 11144610)
8. Bissell M. J., Rizki A., Mian I. S., Tissue architecture: the ultimate regulator of breast epithelial function Current Opinion in Cell Biology 2003 15 6 753 762 (Pubitemid 37487969)
9. Li L., Xie T., Stem cell niche: structure and function Annual Review of Cell and Developmental Biology 2005 21 605 631 (Pubitemid 41740648)
10. Austin J., Kimble J., glp-1 required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans Cell 1987 51 4 589 599
11. Hansen D., Wilson-Berry L., Dang T., Schedl T., Control of the proliferation versus meiotic development decision in the C. elegans germline through regulation of GLD-1 protein accumulation Development 2004 131 1 93 104 (Pubitemid 38111418)
12. Lam N., Chesney M. A., Kimble J., Wnt signaling and CEH-22/tinman/Nkx2.5 specify a stem cell niche in C. elegans Current Biology 2006 16 3 287 295 (Pubitemid 43190228)
13. Xie T., Spradling A. C., A niche maintaining germ line stem cells in the Drosophila ovary Science 2000 290 5490 328 330
14. Walker M. R., Patel K. K., Stappenbeck T. S., The stem cell niche Journal of Pathology 2009 217 2 169 180
15. Shackleton M., Vaillant F., Simpson K. J., Stingl J., Smyth G. K., Asselin-Labat M. L., Wu LI., Lindeman G. J., Visvader J. E., Generation of a functional mammary gland from a single stem cell Nature 2006 439 7072 84 88 (Pubitemid 43053633)
16. Kordon E. C., Smith G. H., An entire functional mammary gland may comprise the progeny from a single cell Development 1998 125 10 1921 1930 (Pubitemid 28274378)
17. DeOme K. B., Faulkin L. J., Bern H. A., Blair P. B., Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice Cancer Research 1959 19 515 520
18. Daniel C. W., Deome K. B., Young J. T., Blair P. B., Faulkin L. J., The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study. 1968 Proceedings of the National Academy of Sciences of the United States of America 1968 61 53 60
19. Young L. J. T., Medina D., DeOme K. B., Daniel C. W., The influence of host and tissue age on life span and growth rate of serially transplanted mouse mammary gland Experimental Gerontology 1971 6 1 49 56
20. Hennighausen L., Robinson G. W., Information networks in the mammary gland Nature Reviews Molecular Cell Biology 2005 6 9 715 725 (Pubitemid 41742795)
21. Schnitt S. J., Collins L. C., Biopsy Interpretation of the Breast 2009 Philadelphia, Pa, USA Wolters Kluwer/Lippincott William Wilkins
22. Akers R. M., Lactation and the Mammary Gland 2002 Ames, Iowa, USA Iowa State Press
23. Polyak K., Hu M., Do myoepithelial cells hold the key for breast tumor progression? Journal of Mammary Gland Biology and Neoplasia 2005 10 3 231 247
24. Schmeichel K. L., Bissell M. J., Modelling tissue-specific signaling and organ function in three dimensions Journal of Cell Science 2003 116 12 2377 2388 (Pubitemid 36790120)
25. Spratt J. S., Tobin G. R., Gross Anatomy of the Breast 1995 Philadelphia, Pa, USA W. B. Saunders
26. McCave E. J., Cass C. A.P., Burg K. J.L., Booth B. W., The normal microenvironment directs mammary gland development Journal of Mammary Gland Biology and Neoplasia 2010 15 3 291 299
27. Silberstein G. B., Role of the stroma in mammary development Breast Cancer Research 2001 3 4 218 223 (Pubitemid 32631700)
28. Wiseman B. S., Werb Z., Development: stromal effects on mammary gland development and breast cancer Science 2002 296 5570 1046 1049 (Pubitemid 34517108)
29. Parmar H., Cunha G. R., Epithelial-stromal interactions in the mouse and human mammary gland in vivo Endocrine-Related Cancer 2004 11 3 437 458 (Pubitemid 39331276)
30. Gyorki D. E., Asselin-Labat M. L., van Rooijen N., Lindeman G. J., Visvader J. E., Resident macrophages influence stem cell activity in the mammary gland Breast Cancer Research 2009 11 4 R62
31. Van Nguyen A., Pollard J. W., Colony stimulating factor-1 is required to recruit macrophages into the mammary gland to facilitate mammary ductal outgrowth Developmental Biology 2002 247 1 11 25 (Pubitemid 34681162)
32. Gouon-Evans V., Lin E. Y., Pollard J. W., Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland development Breast Cancer Research 2002 4 4 155 164 (Pubitemid 35012324)
33. Landskroner-Eiger S., Park J., Israel D., Pollard J. W., Scherer P. E., Morphogenesis of the developing mammary gland: stage-dependent impact of adipocytes Developmental Biology 2010 344 968 978
34. Couldrey C., Moitra J., Vinson C., Anver M., Nagashima K., Green J., Adipose tissue: a vital in vivo role in mammary gland development but not differentiation Developmental Dynamics 2002 223 4 459 468 (Pubitemid 34273452)
35. Medina D., Stromal fibroblasts influence human mammary epithelial cell morphogenesis Proceedings of the National Academy of Sciences of the United States of America 2004 101 14 4723 4724 (Pubitemid 38469145)
36. Brisken C., Park S., Vass T., Lydon J. P., O'Malley B. W., Weinberg R. A., A paracrine role for the epithelial progesterone receptor in mammary gland development Proceedings of the National Academy of Sciences of the United States of America 1998 95 9 5076 5081 (Pubitemid 28208553)
37. Mallepell S., Krust A., Chambon P., Brisken C., Paracrine signaling through the epithelial estrogen receptor is required for proliferation and morphogenesis in the mammary gland Proceedings of the National Academy of Sciences of the United States of America 2006 103 7 2196 2201 (Pubitemid 43271646)
38. Booth B. W., Boulanger C. A., Anderson L. H., Jimenez-Rojo L., Brisken C., Smith G. H., Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics Experimental Cell Research 2010 316 3 422 432
39. McBryan J., Howlin J., Napoletano S., Martin F., Amphiregulin: role in mammary gland development and breast cancer Journal of Mammary Gland Biology and Neoplasia 2008 13 2 159 169
40. Brisken C., Heineman A., Chavarria T., Elenbaas B., Tan J., Dey S. K., McMahon J. A., McMahon A. P., Weinberg R. A., Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling Genes and Development 2000 14 6 650 654 (Pubitemid 30176819)
41. Zeng Y. A., Nusse R., Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture Cell Stem Cell 2010 6 6 568 577
42. Beleut M., Rajaram R. D., Caikovski M., Ayyanan A., Germano D., Choi Y., Schneider P., Brisken C., Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland Proceedings of the National Academy of Sciences of the United States of America 2010 107 7 2989 2994
43. Fata J. E., Kong Y. Y., Li JI., Sasaki T., Irie-Sasaki J., Moorehead R. A., Elliott R., Scully S., Voura E. B., Lacey D. L., Boyle W. J., Khokha R., Penninger J. M., The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development Cell 2000 103 1 41 50
44. Wagner K. U., Boulanger C. A., Henry M. D., Sgagias M., Hennighausen L., Smith G. H., An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal Development 2002 129 6 1377 1386 (Pubitemid 34874159)
45. Matulka L. A., Triplett A. A., Wagner K. U., Parity-induced mammary epithelial cells are multipotent and express cell surface markers associated with stem cells Developmental Biology 2007 303 1 29 44 (Pubitemid 46241114)
46. Yang LI., Moses H. L., Transforming growth factor : tumor suppressor or promoter? Are host immune cells the answer? Cancer Research 2008 68 22 9107 9111
47. Pierce D. F., Johnson M. D., Matsui Y., Robinson S. D., Gold L. I., Purchio A. F., Daniel C. W., Hogan B. L. M., Moses H. L., Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF- 1 Genes and Development 1993 7 12 A 2308 2317 (Pubitemid 24003235)
48. Kordon E. C., McKnight R. A., Jhappan C., Hennighausen L., Merlino G., Smith G. H., Ectopic TGF 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population Developmental Biology 1995 168 1 47 61
49. Flanders K. C., Wakefield L. M., Transforming growth Factor- s and mammary gland involution; functional roles and implications for cancer progression Journal of Mammary Gland Biology and Neoplasia 2009 14 2 131 144
50. Fuxe J., Vincent T., De Herreros A. G., Transcriptional crosstalk between TGF and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes Cell Cycle 2010 9 12 2363 2374
51. Thiery J. P., Sleeman J. P., Complex networks orchestrate epithelial-mesenchymal transitions Nature Reviews Molecular Cell Biology 2006 7 2 131 142 (Pubitemid 43278296)
52. Mani S. A., Guo W., Liao M. J., Eaton E. NG., Ayyanan A., Zhou A. Y., Brooks M., Reinhard F., Zhang C. C., Shipitsin M., Campbell L. L., Polyak K., Brisken C., Yang J., Weinberg R. A., The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 2008 133 4 704 715 (Pubitemid 351636299)
53. Foubert E., De Craene B., Berx G., Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression Breast Cancer Research 2010 12 3 206 216
54. Kozowski L., Zakrzewska I., Tokajuk P., Wojtukiewicz M. Z., Concentration of interleukin-6 (IL-6), interleukin-8 (IL-8) and interleukin-10 (IL-10) in blood serum of breast cancer patients Roczniki Akademii Medycznej w Bialymstoku 2003 48 82 84
55. Salgado R., Junius S., Benoy I., Van Dam P., Vermeulen P., Van Marck E., Huget P., Dirix L. Y., Circulating interleukin-6 predicts survival in patients with metastatic breast cancer International Journal of Cancer 2003 103 5 642 646 (Pubitemid 36091468)
56. Hardy K. M., Booth B. W., Hendrix M. J. C., Salomon D. S., Strizzi L., ErbB/EGF signaling and EMT in mammary development and breast cancer Journal of Mammary Gland Biology and Neoplasia 2010 15 191 199
57. Cannata D., Lann D., Wu Y., Elis S., Sun H., Yakar S., Lazzarino D. A., Wood T. L., LeRoith D., Elevated circulating IGF-I promotes mammary gland development and proliferation Endocrinology 2010 151 12 5751 5761
58. Ruan W., Kleinberg D. L., Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development Endocrinology 1999 140 11 5075 5081
59. Hamelers I. H. L., Steenbergh P. H., Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells Endocrine-Related Cancer 2003 10 2 331 345 (Pubitemid 36758659)
60. Loladze A. V., Stull M. A., Rowzee A. M., DeMarco J., Lantry J. H., Rosen C. J., LeRoith D., Wagner K. U., Hennighausen L., Wood T. L., Epithelial-specific and stage-specific functions of insulin-like growth factor-I during postnatal mammary development Endocrinology 2006 147 11 5412 5423 (Pubitemid 44790596)
61. Alberts B., Johnson A., Lewis J., Raff M., Roberts K., Walters P., Cells in their social context Molecular Biology of the Cell 2002 4th New York, NY, USA Garland Science
62. Aszodi A., Hunziker E. B., Brakebusch C., Fssler R., 1 integrins regulate chondrocyte rotation Genes and Development 2003 17 19 2465 2479
63. Brakebusch C., Grose R., Quondamatteo F., Ramirez A., Jorcano J. L., Pirro A., Svensson M., Herken R., Sasaki T., Timpl R., Werner S., Fssler R., Skin and hair follicle integrity is crucially dependent on 1 integrin expression on keratinocytes EMBO Journal 2000 19 15 3990 4003 (Pubitemid 30608538)
64. Graus-Porta D., Blaess S., Senften M., Littlewood-Evans A., Damsky C., Huang Z., Orban P., Klein R., Schittny J. C., Mller U., 1-Class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex Neuron 2001 31 3 367 379 (Pubitemid 32778557)
65. Faraldo M. M., Deugnier M. A., Lukashev M., Thiery J. P., Glukhova M. A., Perturbation of 1-integrin function alters the development of murine mammary gland EMBO Journal 1998 17 8 2139 2147 (Pubitemid 28171899)
66. Faraldo M. M., Deugnier M. A., Tlouzeau S., Thiery J. P., Glukhova M. A., Perturbation of 1-integrin function in involuting mammary gland results in premature dedifferentiation of secretory epithelial cells Molecular Biology of the Cell 2002 13 10 3521 3531 (Pubitemid 35191372)
67. Taddei I., Deugnier M. A., Faraldo M. M., Petit V., Bouvard D., Medina D., Fssler R., Thiery J. P., Glukhova M. A., 1 Integrin deletion from the basal compartment of the mammary epithelium affects stem cells Nature Cell Biology 2008 10 6 716 722 (Pubitemid 351772937)
68. Naylor M. J., Li NA., Cheung J., Lowe E. T., Lambert E., Marlow R., Wang P., Schatzmann F., Wintermantel T., Schetz G., Clarke A. R., Mueller U., Hynes N. E., Streuli C. H., Ablation of 1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation Journal of Cell Biology 2005 171 4 717 728 (Pubitemid 41668730)
69. Bissell M. J., Labarge M. A., Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment? Cancer Cell 2005 7 1 17 23 (Pubitemid 40126379)
70. LaBarge M. A., Petersen O. W., Bissell M. J., Of microenvironments and mammary stem cells Stem Cell Reviews 2007 3 2 137 146 (Pubitemid 350129716)
71. Labarge M. A., Nelson C. M., Villadsen R., Fridriksdottir A., Ruth J. R., Stampfer M. R., Petersen O. W., Bissell M. J., Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments Integrative Biology 2009 1 1 70 79
72. Booth B. W., Boulanger C. A., Anderson L. H., Jimenez-Rojo L., Brisken C., Smith G. H., Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics Experimental Cell Research 2010 316 3 422 432
73. Dontu G., Jackson K. W., McNicholas E., Kawamura M. J., Abdallah W. M., Wicha M. S., Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells Breast Cancer Research 2004 6 6 R605 R615
74. Liu S., Dontu G., Mantle I. D., Patel S., Ahn N. S., Jackson K. W., Suri P., Wicha M. S., Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells Cancer Research 2006 66 12 6063 6071
75. Gallego M. I., Beachy P. A., Hennighausen L., Robinson G. W., Differential requirements for Shh in mammary tissue and hair follicle morphogenesis Developmental Biology 2002 249 1 131 139
76. Lewis M. T., Hedgehog Signaling in Mouse Mammary Gland Development and Neoplasia Journal of Mammary Gland Biology and Neoplasia 2001 6 1 53 66 (Pubitemid 33640646)
77. Kouros-Mehr H., Werb Z., Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis Developmental Dynamics 2006 235 12 3404 3412 (Pubitemid 44888206)
78. Lewis M. T., Ross S., Strickland P. A., Sugnet C. W., Jimenez E., Hui C. C., Daniel C. W., The Gli2 transcription factor is required for normal mouse mammary gland development Developmental Biology 2001 238 1 133 144 (Pubitemid 32939291)
79. Hatsell S. J., Cowin P., Gli3-mediated repression of Hedgehog targets is required for normal mammary development Development 2006 133 18 3661 3670 (Pubitemid 44614288)
80. Lewis M. T., Veltmaat J. M., Next top, the twilight zone: hedgehog network regulation of mammary gland development Journal of Mammary Gland Biology and Neoplasia 2004 9 2 165 181 (Pubitemid 39177501)
81. Boulanger C. A., Mack D. L., Booth B. W., Smith G. H., Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo Proceedings of the National Academy of Sciences of the United States of America 2007 104 10 3871 3876 (Pubitemid 47181546)
82. Booth B. W., Mack D. L., Androutsellis-Theotokis A., McKay R. D. G., Boulanger C. A., Smith G. H., The mammary microenvironment alters the differentiation repertoire of neural stem cells Proceedings of the National Academy of Sciences of the United States of America 2008 105 39 14891 14896
83. Bussard K. M., Boulanger C. A., Booth B. W., Bruno R. D., Smith G. H., Reprogramming human cancer cells in the mouse mammary gland Cancer Research 2010 70 15 6336 6343
84. Mintz B., Illmensee K., Normal genetically mosaic mice produced from malignant teratocarcinoma cells Proceedings of the National Academy of Sciences of the United States of America 1975 72 9 3585 3589
85. Rous P., A transmissible avian neoplasm Journal of Experimental Medicine 1979 150 4 738 753
86. Stoker A. W., Hatier C., Bissell M. J., The embryonic environment strongly attenuates v-src oncogenesis in mesenchymal and epithelial tissues, but not in endothelia Journal of Cell Biology 1990 111 1 217 228
87. Felsher D. W., Cancer revoked: oncogenes as therapeutic targets Nature Reviews Cancer 2003 3 5 375 380 (Pubitemid 37328857)
88. Hochedlinger K., Blelloch R., Brennan C., Yamada Y., Kim M., Chin L., Jaenisch R., Reprogramming of a melanoma genome by nuclear transplantation Genes and Development 2004 18 15 1875 1885 (Pubitemid 39025097)
89. Ma X. J., Dahiya S., Richardson E., Erlander M., Sgroi D. C., Gene expression profiling of the tumor microenvironment during breast cancer progression Breast Cancer Research 2009 11 1 R7
90. Bussard K. M., Venzon D. J., Mastro A. M., Osteoblasts are a major source of inflammatory cytokines in the tumor microenvironment of bone metastatic breast cancer Journal of Cellular Biochemistry 2010 111 5 1138 1148
91. Booth B. W., Boulanger C. A., Anderson L. H., Smith G. H., The normal mammary microenvironment suppresses the tumorigenic phenotype of mouse mammary tumor virus-neu-transformed mammary tumor cells Oncogene 2011 30 6 679 689