Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines

Journal of Biological Chemistry

Volumn 286, Issue 25, 2011, Pages 22291-22299

  Li, Xiang ^a,b   Wen, Weihong ^a   Liu, Kangdong ^a,b   Zhu, Feng ^a   Malakhova, Margarita ^a   Peng, Cong ^a   Li, Tingting ^c   Kim, Hong Gyum ^a   Ma, Weiya ^a   Yeon Cho, Yong ^a   Bode, Ann M ^a   Dong, Ziming ^b   Dong, Zigang ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ZHENGZHOU UNIVERSITY   (China)

^c Luoyang Central Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEINS; BREAST CANCER CELLS; BREAST TISSUES; DUCTAL CARCINOMA; HUMAN BREAST; HUMAN BREAST CANCER CELLS; MAMMARY EPITHELIAL CELLS; P-21 ACTIVATED KINASE; PHYSIOLOGICAL PROCESS; PROTEIN KINASE;

AMINO ACIDS; CELL CULTURE; CHEMOTHERAPY; DISEASES; ENZYME ACTIVITY; PHOSPHORYLATION; TISSUE;

CELL DEATH;

CASPASE 7; DOXORUBICIN; P21 ACTIVATED KINASE 2; SERINE; THREONINE;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CARCINOMA; BREAST EPITHELIUM; CANCER CELL; CANCER INVASION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; APOPTOSIS; BASE SEQUENCE; BREAST NEOPLASMS; CARCINOMA, DUCTAL; CASPASE 7; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; P21-ACTIVATED KINASES; PHOSPHORYLATION; PROTEIN TRANSPORT;

EID: 79959367758     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.236596     Document Type: Article

References (43)

1. (2003) Cent. Eur. J. Public Health 11, 177-179
2. Puglisi, F., Andreetta, C., and Fasola, G. (2006) Expert Opin. Pharmacother. 7, 2309-2318
3. Haagenson, K. K., and Wu, G. S. (2010) Cancer Metastasis Rev. 29, 143-149
4. Dowsett, M., Johnston, S., Martin, L. A., Salter, J., Hills, M., Detre, S., Gutierrez, M. C., Mohsin, S. K., Shou, J., Allred, D. C., Schiff, R., Osborne, C. K., and Smith, I. (2005) Endocr. Relat. Cancer 12, Suppl. 1, S113-S117
5. Arpino, G., Green, S. J., Allred, D. C., Lew, D., Martino, S., Osborne, C. K., and Elledge, R. M. (2004) Clin. Cancer Res. 10, 5670-5676
6. Gee, J. M., Robertson, J. F., Gutteridge, E., Ellis, I. O., Pinder, S. E., Rubini, M., and Nicholson, R. I. (2005) Endocr. Relat. Cancer 12, Suppl. 1, S99-S111
7. Kirkegaard, T., Witton, C. J., McGlynn, L. M., Tovey, S. M., Dunne, B., Lyon, A., and Bartlett, J. M. (2005) J. Pathol. 207, 139-146
8. Gutierrez, M. C., Detre, S., Johnston, S., Mohsin, S. K., Shou, J., Allred, D. C., Schiff, R., Osborne, C. K., and Dowsett, M. (2005) J. Clin. Oncol. 23, 2469-2476
9. Holm, C., Rayala, S., Jirström, K., Stål, O., Kumar, R., and Landberg, G. (2006) J. Natl. Cancer Inst. 98, 671-680
10. Riggins, R. B., Schrecengost, R. S., Guerrero, M. S., and Bouton, A. H. (2007) Cancer Lett. 256, 1-24
11. Manser, E., Leung, T., Salihuddin, H., Zhao, Z. S., and Lim, L. (1994) Nature 367, 40-46
12. Molli, P. R., Li, D. Q., Murray, B. W., Rayala, S. K., and Kumar, R. (2009) Oncogene 28, 2545-2555
13. Hofmann, C., Shepelev, M., and Chernoff, J. (2004) J. Cell Sci. 117, 4343-4354
14. Schürmann, A., Mooney, A. F., Sanders, L. C., Sells, M. A., Wang, H. G., Reed, J. C., and Bokoch, G. M. (2000) Mol. Cell. Biol. 20, 453-461
15. Nheu, T., He, H., Hirokawa, Y., Walker, F., Wood, J., and Maruta, H. (2004) Cell Cycle 3, 71-74
16. Rayala, S. K., Talukder, A. H., Balasenthil, S., Tharakan, R., Barnes, C. J., Wang, R. A., Aldaz, C. M., Khan, S., and Kumar, R. (2006) Cancer Res. 66, 1694-1701
17. Roig, J., and Traugh, J. A. (1999) J. Biol. Chem. 274, 31119-31122
18. Walter, B. N., Huang, Z., Jakobi, R., Tuazon, P. T., Alnemri, E. S., Litwack, G., and Traugh, J. A. (1998) J. Biol. Chem. 273, 28733-28739
19. Jakobi, R., Moertl, E., and Koeppel, M. A. (2001) J. Biol. Chem. 276, 16624-16634
20. Fischer, U., Stroh, C., and Schulze-Osthoff, K. (2006) Oncogene 25, 152-159
21. Jakobi, R., McCarthy, C. C., Koeppel, M. A., and Stringer, D. K. (2003) J. Biol. Chem. 278, 38675-38685
22. Ling, J., Morley, S. J., and Traugh, J. A. (2005) EMBO J. 24, 4094-4105
23. Kumar, R., Gururaj, A. E., and Barnes, C. J. (2006) Nat. Rev. 6, 459-471
24. Li, T., Zhang, J., Zhu, F., Wen, W., Zykova, T., Li, X., Liu, K., Peng, C., Ma, W., Shi, G., Dong, Z., Bode, A. M., and Dong, Z. (2011) Carcinogenesis 32, 659-666
25. Hsu, Y. H., Johnson, D. A., and Traugh, J. A. (2008) J. Biol. Chem. 283, 36397-36405
26. Tuazon, P. T., Lorenson, M. Y., Walker, A. M., and Traugh, J. A. (2002) FEBS Lett. 515, 84-88
27. Jakobi, R., Huang, Z., Walter, B. N., Tuazon, P. T., and Traugh, J. A. (2000) Eur. J. Biochem. 267, 4414-4421
28. Blom, N., Gammeltoft, S., and Brunak, S. (1999) J. Mol. Biol. 294, 1351-1362
29. Lakhani, S. A., Masud, A., Kuida, K., Porter, G. A., Jr., Booth, C. J., Mehal, W. Z., Inayat, I., and Flavell, R. A. (2006) Science 311, 847-851
30. Lamkanfi, M., and Kanneganti, T. D. (2010) Int. J. Biochem. Cell Biol. 42, 21-24
31. Cardone, M. H., Salvesen, G. S., Widmann, C., Johnson, G., and Frisch, S. M. (1997) Cell 90, 315-323
32. Yang, X., Stennicke, H. R., Wang, B., Green, D. R., Jänicke, R. U., Srinivasan, A., Seth, P., Salvesen, G. S., and Froelich, C. J. (1998) J. Biol. Chem. 273, 34278-34283
33. Kuribayashi, K., Mayes, P. A., and El-Deiry, W. S. (2006) Cancer Biol. Ther. 5, 763-765
34. Hajra, K. M., and Liu, J. R. (2004) Apoptosis 9, 691-704
35. Kim, P. K., Mahidhara, R., and Seol, D. W. (2001) Drug Resist. Updat. 4, 293-296
36. Cillessen, S. A., Hess, C. J., Hooijberg, E., Castricum, K. C., Kortman, P., Denkers, F., Vos, W., van de Wiel, M. A., Schuurhuis, G. J., Ossenkoppele, G. J., Meijer, C. J., and Oudejans, J. J. (2007) Clin. Cancer Res. 13, 7012-7021
37. Hara, S., Miyake, H., Arakawa, S., Kamidono, S., and Hara, I. (2001) J. Urol. 166, 2491-2494
38. Kurokawa, M., and Kornbluth, S. (2009) Cell 138, 838-854
39. Jia, S. H., Parodo, J., Kapus, A., Rotstein, O. D., and Marshall, J. C. (2008) J. Biol. Chem. 283, 5402-5413
40. Voss, O. H., Kim, S., Wewers, M. D., and Doseff, A. I. (2005) J. Biol. Chem. 280, 17371-17379
41. Lamkanfi, M., Moreira, L. O., Makena, P., Spierings, D. C., Boyd, K., Murray, P. J., Green, D. R., and Kanneganti, T. D. (2009) Blood 113, 2742-2745
42. Marlin, J. W., Eaton, A., Montano, G. T., Chang, Y. W., and Jakobi, R. (2009) Neoplasia 11, 286-297
43. Liu, R., Wang, X., Chen, G. Y., Dalerba, P., Gurney, A., Hoey, T., Sherlock, G., Lewicki, J., Shedden, K., and Clarke, M. F. (2007) N. Engl. J. Med. 356, 217-226