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Volumn 2011, Issue , 2011, Pages

Acute myeloid leukemia with the t(8;21) translocation: Clinical consequences and biological implications

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; CALPAIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CONNEXIN 43; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTARABINE; DNA DIRECTED RNA POLYMERASE; DNA METHYLTRANSFERASE; ETO PROTEIN; FLT3 LIGAND; GFI1 PROTEIN; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; JANUS KINASE 2; MICRORNA; NOTCH RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN; PROTEIN P53; RAS PROTEIN; RETINOIC ACID; STEM CELL FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX5; TRANSCRIPTION FACTOR POU4F1; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; VALPROIC ACID; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 79959366179     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/104631     Document Type: Review
Times cited : (77)

References (211)
  • 2
    • 0015694741 scopus 로고
    • Identification of a translocation with quinacrine fluorescence in a patient with acute leukemia
    • Rowley J. D., Identification of a translocation with quinacrine fluorescence in a patient with acute leukemia Annales de Genetique 1973 16 2 109 112
    • (1973) Annales de Genetique , vol.16 , Issue.2 , pp. 109-112
    • Rowley, J.D.1
  • 3
    • 85047688311 scopus 로고    scopus 로고
    • Prognostic impact of acute myeloid leukemia classification: Importance of detection of recurring cytogenetic abnormalities and multilineage dysplasia on survival
    • DOI 10.1309/EM7K-CQR4-GLMH-RCX4
    • Arber D. A., Stein A. S., Carter N. H., Ikle D., Forman S. J., Slovak M. L., Prognostic impact of acute myeloid leukemia classification: importance of detection of recurring cytogenetic abnormalities and multilineage dysplasia on survival American Journal of Clinical Pathology 2003 119 5 672 680 (Pubitemid 37046388)
    • (2003) American Journal of Clinical Pathology , vol.119 , Issue.5 , pp. 672-680
    • Arber, D.A.1    Stein, A.S.2    Carter, N.H.3    Ikle, D.4    Forman, S.J.5    Slovak, M.L.6
  • 5
    • 70350093158 scopus 로고    scopus 로고
    • Cytogenetic profile of de novo acute myeloid leukemia: A study based on 1432 patients in a single institution of China
    • Cheng Y., Wang Y., Wang H., Chen Z., Lou J., Xu H., Wang H., Qian W., Meng H., Lin M., Jin J., Cytogenetic profile of de novo acute myeloid leukemia: a study based on 1432 patients in a single institution of China Leukemia 2009 23 10 1801 1806
    • (2009) Leukemia , vol.23 , Issue.10 , pp. 1801-1806
    • Cheng, Y.1    Wang, Y.2    Wang, H.3    Chen, Z.4    Lou, J.5    Xu, H.6    Wang, H.7    Qian, W.8    Meng, H.9    Lin, M.10    Jin, J.11
  • 7
    • 77955914238 scopus 로고    scopus 로고
    • Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
    • Grimwade D., Hills R. K., Moorman A. V., Walker H., Chatters S., Goldstone A. H., Wheatley K., Harrison C. J., Burnett A. K., Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials Blood 2010 116 3 354 365
    • (2010) Blood , vol.116 , Issue.3 , pp. 354-365
    • Grimwade, D.1    Hills, R.K.2    Moorman, A.V.3    Walker, H.4    Chatters, S.5    Goldstone, A.H.6    Wheatley, K.7    Harrison, C.J.8    Burnett, A.K.9
  • 8
    • 7444267879 scopus 로고    scopus 로고
    • Cytogenetic profile in de novo acute myeloid leukemia with FAB subtypes M0, M1, and M2: A study based on 652 cases analyzed with morphology, cytogenetics, and fluorescence in situ hybridization
    • DOI 10.1016/j.cancergencyto.2004.03.008, PII S0165460804001372
    • Klaus M., Haferlach T., Schnittger S., Kern W., Hiddemann W., Schoch C., Cytogenetic profile in de novo acute myeloid leukemia with FAB subtypes M0, M1, and M2: a study based on 652 cases analyzed with morphology, cytogenetics, and fluorescence in situ hybridization Cancer Genetics and Cytogenetics 2004 155 1 47 56 (Pubitemid 39446612)
    • (2004) Cancer Genetics and Cytogenetics , vol.155 , Issue.1 , pp. 47-56
    • Klaus, M.1    Haferlach, T.2    Schnittger, S.3    Kern, W.4    Hiddemann, W.5    Schoch, C.6
  • 9
    • 27844457594 scopus 로고    scopus 로고
    • Population-based age-specific incidences of cytogenetic subgroups of acute myeloid leukemia
    • Bacher U., Kern W., Schnittger S., Hiddemann W., Haferlach T., Schoch C., Population-based age-specific incidences of cytogenetic subgroups of acute myeloid leukemia Haematologica 2005 90 11 1502 1510 (Pubitemid 41658763)
    • (2005) Haematologica , vol.90 , Issue.11 , pp. 1502-1510
    • Bacher, U.1    Kern, W.2    Schnittger, S.3    Hiddemann, W.4    Haferlach, T.5    Schoch, C.6
  • 10
    • 0038712179 scopus 로고    scopus 로고
    • Flt3-mediated signaling in human acute myelogenous leukemia (AML) blasts: A functional characterization of the effects of Flt3-ligand in AML cell populations with and without genetic Flt3 abnormalities
    • Bruserud., Hovland R., Wergeland L., Huang T. S., Gjertsen B. T., Flt3-mediated signaling in human acute myelogenous leukemia (AML) blasts: a functional characterization of the effects of Flt3-ligand in AML cell populations with and without genetic Flt3 abnormalities Haematologica 2003 88 4 416 428 (Pubitemid 36547128)
    • (2003) Haematologica , vol.88 , Issue.4 , pp. 416-428
    • Bruserud, O.1    Hovland, R.2    Wergeland, L.3    Huang, T.-S.4    Gjertsen, B.T.5
  • 11
    • 55749083387 scopus 로고    scopus 로고
    • Advances in molecular genetics and treatment of core-binding factor acute myeloid leukemia
    • Mrzek K., Marcucci G., Paschka P., Bloomfield C. D., Advances in molecular genetics and treatment of core-binding factor acute myeloid leukemia Current Opinion in Oncology 2008 20 6 711 718
    • (2008) Current Opinion in Oncology , vol.20 , Issue.6 , pp. 711-718
    • Mrzek, K.1    Marcucci, G.2    Paschka, P.3    Bloomfield, C.D.4
  • 13
    • 0033485565 scopus 로고    scopus 로고
    • Chromosomal abnormalities in 478 children with acute myeloid leukemia: Clinical characteristics and treatment outcome in a Cooperative Pediatric Oncology Group study-POG 8821
    • Raimondi S. C., Chang M. N., Ravindranath Y., Behm F. G., Gresik M. V., Steuber C. P., Weinstein H. J., Carrol A. J., Chromosomal abnormalities in 478 children with acute myeloid leukemia: clinical characteristics and treatment outcome in a Cooperative Pediatric Oncology Group study-POG 8821 Blood 1999 94 11 3707 3716
    • (1999) Blood , vol.94 , Issue.11 , pp. 3707-3716
    • Raimondi, S.C.1    Chang, M.N.2    Ravindranath, Y.3    Behm, F.G.4    Gresik, M.V.5    Steuber, C.P.6    Weinstein, H.J.7    Carrol, A.J.8
  • 14
    • 28544433591 scopus 로고    scopus 로고
    • Treatment and long-term results in children with acute myeloid leukaemia treated according to the AIEOP AML protocols
    • DOI 10.1038/sj.leu.2403869, PII 2403869
    • Pession A., Rondelli R., Basso G., Rizzari C., Testi A. M., Fagioli F., De Stefano P., Locatelli F., Treatment and long-term results in children with acute myeloid leukaemia treated according to the AIEOP AML protocols Leukemia 2005 19 12 2043 2053 (Pubitemid 41741596)
    • (2005) Leukemia , vol.19 , Issue.12 , pp. 2043-2053
    • Pession, A.1    Rondelli, R.2    Basso, G.3    Rizzari, C.4    Testi, A.M.5    Fagioli, F.6    De Stefano, P.7    Locatelli, F.8
  • 20
    • 77950519512 scopus 로고    scopus 로고
    • OGG1 is a novel prognostic indicator in acute myeloid leukaemia
    • Liddiard K., Hills R., Burnett A. K., Darley R. L., Tonks A., OGG1 is a novel prognostic indicator in acute myeloid leukaemia Oncogene 2010 29 13 2005 2012
    • (2010) Oncogene , vol.29 , Issue.13 , pp. 2005-2012
    • Liddiard, K.1    Hills, R.2    Burnett, A.K.3    Darley, R.L.4    Tonks, A.5
  • 21
    • 0035878575 scopus 로고    scopus 로고
    • Translocation (8;17;15;21)(q22;q23;q15;q22) in acute myeloid leukemia (M2): A four-way variant of t(8;21)
    • DOI 10.1016/S0165-4608(01)00404-6, PII S0165460801004046
    • Vieira L., Oliveira V., Ambrsio A. P., Marques B., Pereira A. M., Hagemeijer A., Boavida M. G., Translocation (8;17;15;21)(q22;q23;q15;q22) in acute myeloid leukemia (M2): a four-way variant of t(8;21) Cancer Genetics and Cytogenetics 2001 128 2 104 107 (Pubitemid 32706581)
    • (2001) Cancer Genetics and Cytogenetics , vol.128 , Issue.2 , pp. 104-107
    • Vieira, L.1    Oliveira, V.2    Ambrosio, A.P.3    Marques, B.4    Pereira, A.M.5    Hagemeijer, A.6    Boavida, M.G.7
  • 22
    • 15844407827 scopus 로고    scopus 로고
    • Pericentric chromosome 8 inversion associated with the 5′ RUNX1/3′CBFA2T1 gene in acute myeloid leukemia cases
    • DOI 10.1007/s00277-004-0960-x
    • Anelli L., Albano F., Zagaria A., Liso A., Cuneo A., Mancini M., Liso V., Rocchi M., Specchia G., Pericentric chromosome 8 inversion associated with the 5′ RUNX1/ 3′ CBFA2T1 gene in acute myeloid leukemia cases Annals of Hematology 2005 84 4 245 249 (Pubitemid 40425071)
    • (2005) Annals of Hematology , vol.84 , Issue.4 , pp. 245-249
    • Anelli, L.1    Albano, F.2    Zagaria, A.3    Liso, A.4    Cuneo, A.5    Mancini, M.6    Liso, V.7    Rocchi, M.8    Specchia, G.9
  • 24
    • 34547941839 scopus 로고    scopus 로고
    • Acute myeloid leukemia with the 8q22;21q22 translocation: Secondary mutational events and alternative t(8;21) transcripts
    • DOI 10.1182/blood-2006-11-019265
    • Peterson L. F., Boyapati A., Ahn E. Y., Biggs J. R., Akiko J. O., Lo M. C., Yan M., Zhang D. E., Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts Blood 2007 110 3 799 805 (Pubitemid 47267414)
    • (2007) Blood , vol.110 , Issue.3 , pp. 799-805
    • Peterson, L.F.1    Boyapati, A.2    Ahn, E.-Y.3    Biggs, J.R.4    Akiko, J.O.5    Lo, M.-C.6    Yan, M.7    Zhang, D.-E.8
  • 25
    • 33747438883 scopus 로고    scopus 로고
    • Identification of additional cytogenetic and molecular genetic abnormalities in acute myeloid leukaemia with t(8;21)/AML1-ETO
    • DOI 10.1111/j.1365-2141.2006.06229.x
    • Kuchenbauer F., Schnittger S., Look T., Gilliland G., Tenen D., Haferlach T., Hiddemann W., Buske C., Schoch C., Identification of additional cytogenetic and molecular genetic abnormalities in acute myeloid leukaemia with t(8;21)/AML1-ETO British Journal of Haematology 2006 134 6 616 619 (Pubitemid 44253604)
    • (2006) British Journal of Haematology , vol.134 , Issue.6 , pp. 616-619
    • Kuchenbauer, F.1    Schnittger, S.2    Look, T.3    Gilliland, G.4    Tenen, D.5    Haferlach, T.6    Hiddemann, W.7    Buske, C.8    Schoch, C.9
  • 32
    • 33344471932 scopus 로고    scopus 로고
    • KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese ChildhoodAMLCooperative Study Group
    • DOI 10.1182/blood-2005-08-3408
    • Shimada A., Taki T., Tabuchi K., KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group Blood 2006 107 5 1806 1809 (Pubitemid 43289357)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1806-1809
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Tawa, A.4    Horibe, K.5    Tsuchida, M.6    Hanada, R.7    Tsukimoto, I.8    Hayashi, Y.9
  • 35
    • 79959352739 scopus 로고    scopus 로고
    • Mutations in the Fms-related tyrosine kinase 3 (FLT3) gene independently predict poor outcome in acute myeloid leukemia (AML) with t(8;21): A study of the outcome in acute myeloid leukemia (AML) with t(8;21): A study of the German-Austrian AML Study Group (AMLSG)
    • abstract no 825
    • Paschka P., Du J., Schlenk R. F., Mutations in the Fms-related tyrosine kinase 3 (FLT3) gene independently predict poor outcome in acute myeloid leukemia (AML) with t(8;21): a study of the outcome in acute myeloid leukemia (AML) with t(8;21): a study of the German-Austrian AML Study Group (AMLSG) ASH Annual Meeting Abstracts 2009 114 22. abstract no 825
    • (2009) ASH Annual Meeting Abstracts , vol.114 , Issue.22
    • Paschka, P.1    Du, J.2    Schlenk, R.F.3
  • 36
    • 34447641442 scopus 로고    scopus 로고
    • JAK2V617F as progression marker in CMPD and as cooperative mutation in AML with trisomy 8 and t(8;21): A comparative study on 1103 CMPD and 269 AML cases [13]
    • DOI 10.1038/sj.leu.2404707, PII 2404707
    • Schnittger S., Bacher U., Kern W., Haferlach T., Haferlach C., JAK2V617F as progression marker in CMPD and as cooperative mutation in AML with trisomy 8 and t(8;21): a comparative study on 1103 CMPD and 269 AML cases Leukemia 2007 21 8 1843 1845 (Pubitemid 47090133)
    • (2007) Leukemia , vol.21 , Issue.8 , pp. 1843-1845
    • Schnittger, S.1    Bacher, U.2    Kern, W.3    Haferlach, T.4    Haferlach, C.5
  • 37
    • 56549117415 scopus 로고    scopus 로고
    • KIT and FLT3 receptor tyrosine kinase mutations in acute myeloid leukemia with favorable cytogenetics: Two novel mutations and selective occurrence in leukemia subtypes and age groups
    • Sritana N., Auewarakul C. U., KIT and FLT3 receptor tyrosine kinase mutations in acute myeloid leukemia with favorable cytogenetics: two novel mutations and selective occurrence in leukemia subtypes and age groups Experimental and Molecular Pathology 2008 85 3 227 231
    • (2008) Experimental and Molecular Pathology , vol.85 , Issue.3 , pp. 227-231
    • Sritana, N.1    Auewarakul, C.U.2
  • 41
    • 33344465478 scopus 로고    scopus 로고
    • KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival
    • DOI 10.1182/blood-2005-04-1466
    • Schnittger S., Kohl T. M., Haferlach T., Kern W., Hiddemann W., Spiekermann K., Schoch C., KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival Blood 2006 107 5 1791 1799 (Pubitemid 43289355)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1791-1799
    • Schnittger, S.1    Kohl, T.M.2    Haferlach, T.3    Kern, W.4    Hiddemann, W.5    Spiekermann, K.6    Schoch, C.7
  • 42
    • 33750931565 scopus 로고    scopus 로고
    • JAK2V617F mutations as cooperative genetic lesions in t(8;21)-positive acute myeloid leukemia
    • Dhner K., Du J., Corbacioglu A., Scholl C., Schlenk R. F., Dhner H., JAK2V617F mutations as cooperative genetic lesions in t(8;21)-positive acute myeloid leukemia Haematologica 2006 91 11 1569 1570 (Pubitemid 44736129)
    • (2006) Haematologica , vol.91 , Issue.11 , pp. 1569-1570
    • Dohner, K.1    Du, J.2    Corbacioglu, A.3    Scholl, C.4    Schlenk, R.F.5    Dohner, H.6
  • 43
    • 52149092181 scopus 로고    scopus 로고
    • Clinical significance of the most common chromosome translocations in adult acute myeloid leukemia
    • Mrzek K., Bloomfield C. D., Clinical significance of the most common chromosome translocations in adult acute myeloid leukemia Journal of the National Cancer InstituteMonographs 2008 39 52 57
    • (2008) Journal of the National Cancer InstituteMonographs , Issue.39 , pp. 52-57
    • Mrzek, K.1    Bloomfield, C.D.2
  • 44
    • 0036120919 scopus 로고    scopus 로고
    • Identification of ins(8;21) with AML1/ETO fusion in acute myelogenous leukemia M2 by molecular cytogenetics
    • DOI 10.1016/S0165-4608(01)00555-6, PII S0165460801005556
    • Urioste M., Martnez-Ramrez A., Cigudosa J. C., Mateo M. S., Martnez P., Contra T., Bentez J., Identification of ins(8;21) with AML1/ETO fusion in acute myelogenous leukemia M2 by molecular cytogenetics Cancer Genetics and Cytogenetics 2002 133 1 83 86 (Pubitemid 34224881)
    • (2002) Cancer Genetics and Cytogenetics , vol.133 , Issue.1 , pp. 83-86
    • Urioste, M.1    Martinez-Ramirez, A.2    Cigudosa, J.C.3    Mateo, M.S.4    Martinez, P.5    Contra, T.6    Benitez, J.7
  • 46
    • 15244347468 scopus 로고    scopus 로고
    • Tetraploidy or near-tetraploidy clones with double 8;21 translocation: A non-random additional anomaly of acute myeloid leukemia with t(8;21)(q22;q22)
    • Xiao Z., Liu S., Liu X., Yu M., Hao Y., Tetraploidy or near-tetraploidy clones with double 8;21 translocation: a non-random additional anomaly of acute myeloid leukemia with t(8;21)(q22;q22) Haematologica 2005 90 3 413 414 (Pubitemid 40388998)
    • (2005) Haematologica , vol.90 , Issue.3 , pp. 413-414
    • Xiao, Z.1    Liu, S.2    Liu, X.3    Yu, M.4    Hao, Y.5
  • 47
    • 39149092043 scopus 로고    scopus 로고
    • Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples
    • Shih L. Y., Liang D. C., Huang C. F., Chang Y. T., Lai C. L., Lin T. H., Yang C. P., Hung I. J., Liu H. C., Jaing T. H., Wang L. Y., Yeh T. C., Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples Leukemia 2008 22 2 303 307
    • (2008) Leukemia , vol.22 , Issue.2 , pp. 303-307
    • Shih, L.Y.1    Liang, D.C.2    Huang, C.F.3    Chang, Y.T.4    Lai, C.L.5    Lin, T.H.6    Yang, C.P.7    Hung, I.J.8    Liu, H.C.9    Jaing, T.H.10    Wang, L.Y.11    Yeh, T.C.12
  • 48
    • 79959361660 scopus 로고    scopus 로고
    • Differential contributions of c-kit activating mutations to promotion of AML1-ETO associated neoplasia
    • abstract no. 4195
    • Coppersmith H. J., Kimand H.-G., Klug C., Differential contributions of c-kit activating mutations to promotion of AML1-ETO associated neoplasia ASH Annual Meeting Abstracts 2010 116 21. abstract no. 4195
    • (2010) ASH Annual Meeting Abstracts , vol.116 , Issue.21
    • Coppersmith, H.J.1    Kimand, H.-G.2    Klug, C.3
  • 50
    • 79951815187 scopus 로고    scopus 로고
    • N-RasG12D induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene
    • Chou F.-S., Wunderlich M., Griesinger A., Mulloy J. C., N-RasG12D induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene Blood 2011 117 7 2237 2240
    • (2011) Blood , vol.117 , Issue.7 , pp. 2237-2240
    • Chou, F.-S.1    Wunderlich, M.2    Griesinger, A.3    Mulloy, J.C.4
  • 51
    • 15044352509 scopus 로고    scopus 로고
    • Novel missense mutations in the tyrosine kinase domain of the platelet-derived growth factor receptor α (PDGFRA) gene in childhood acute myeloid leukemia with t(8;21) (q22;q22) or inv(16) (p13q22) [10]
    • DOI 10.1038/sj.leu.2403638
    • Hiwatari M., Taki T., Tsuchida M., Hanada R., Hongo T., Sako M., Hayashi Y., Novel missense mutations in the tyrosine kinase domain of the platelet-derived growth factor receptor (PDGFRA) gene in childhood acute myeloid leukemia with t(8;21) (q22;q22) or inv(16) (p13q22) [10] Leukemia 2005 19 3 476 477 (Pubitemid 40403334)
    • (2005) Leukemia , vol.19 , Issue.3 , pp. 476-477
    • Hiwatari, M.1    Taki, T.2    Tsuchida, M.3    Hanada, R.4    Hongo, T.5    Sako, M.6    Hayashi, Y.7
  • 52
    • 15044358998 scopus 로고    scopus 로고
    • CEBPA point mutations in hematological malignancies
    • DOI 10.1038/sj.leu.2403614
    • Leroy H., Roumier C., Huyghe P., Biggio V., Fenaux P., Preudhomme C., CEBPA point mutations in hematological malignancies Leukemia 2005 19 3 329 334 (Pubitemid 40409478)
    • (2005) Leukemia , vol.19 , Issue.3 , pp. 329-334
    • Leroy, H.1    Roumier, C.2    Huyghe, P.3    Biggio, V.4    Fenaux, P.5    Preudhomme, C.6
  • 53
    • 77955907891 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication
    • Paschka P., Schlenk R. F., Gaidzik V. I., Habdank M., Krnke J., Bullinger L., Spth D., Kayser S., Zucknick M., Gtze K., Horst H.-A., Germing U., Dhner H., Dhner K., IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication Journal of Clinical Oncology 2010 28 22 3636 3643
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.22 , pp. 3636-3643
    • Paschka, P.1    Schlenk, R.F.2    Gaidzik, V.I.3    Habdank, M.4    Krnke, J.5    Bullinger, L.6    Spth, D.7    Kayser, S.8    Zucknick, M.9    Gtze, K.10    Horst, H.-A.11    Germing, U.12    Dhner, H.13    Dhner, K.14
  • 55
    • 65349103909 scopus 로고    scopus 로고
    • Therapy-related acute myeloid leukemia with t(8;21) (q22;q22) shares many features with de novo acute myeloid leukemia with t(8;21)(q22;q22) but does not have a favorable outcome
    • Gustafson S. A., Lin P., Chen S. U. S., Chen L., Abruzzo L. V., Luthra R., Medeiros L. J., Wang SA. A., Therapy-related acute myeloid leukemia with t(8;21) (q22;q22) shares many features with de novo acute myeloid leukemia with t(8;21)(q22;q22) but does not have a favorable outcome American Journal of Clinical Pathology 2009 131 5 647 655
    • (2009) American Journal of Clinical Pathology , vol.131 , Issue.5 , pp. 647-655
    • Gustafson, S.A.1    Lin, P.2    Chen, S.U.S.3    Chen, L.4    Abruzzo, L.V.5    Luthra, R.6    Medeiros, L.J.7    Wang, S.A.8
  • 56
    • 67849086588 scopus 로고    scopus 로고
    • Therapy-related acute myeloid leukemia after concurrent chemoradiotherapy for esophageal cancer: Report of two cases
    • Chang H., Chuang C. L., Hsien K. C., Therapy-related acute myeloid leukemia after concurrent chemoradiotherapy for esophageal cancer: report of two cases Tumori 2009 95 3 371 373
    • (2009) Tumori , vol.95 , Issue.3 , pp. 371-373
    • Chang, H.1    Chuang, C.L.2    Hsien, K.C.3
  • 57
    • 33846704428 scopus 로고    scopus 로고
    • Two cases of secondary acute myeloid leukemia accompanying adult T-cell leukemia/lymphoma
    • DOI 10.1532/IJH97.06145
    • Owatari S., Otsuka M., Uozumi K., Takeshita T., Hanada S., Two cases of secondary acute myeloid leukemia accompanying adult T-cell leukemia/lymphoma International Journal of Hematology 2007 85 1 32 35 (Pubitemid 46193287)
    • (2007) International Journal of Hematology , vol.85 , Issue.1 , pp. 32-35
    • Owatari, S.1    Otsuka, M.2    Uozumi, K.3    Takeshita, T.4    Hanada, S.5
  • 58
    • 0026757174 scopus 로고
    • Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
    • Erickson P., Gao J., Chang K. S., Look T., Whisenant E., Raimondi S., Lasher R., Trujillo J., Rowley J., Drabkin H., Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt Blood 1992 80 7 1825 1831
    • (1992) Blood , vol.80 , Issue.7 , pp. 1825-1831
    • Erickson, P.1    Gao, J.2    Chang, K.S.3    Look, T.4    Whisenant, E.5    Raimondi, S.6    Lasher, R.7    Trujillo, J.8    Rowley, J.9    Drabkin, H.10
  • 60
    • 33745917083 scopus 로고    scopus 로고
    • The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
    • DOI 10.1073/pnas.0603463103
    • Plevin M. J., Zhang J., Guo C., Roeder R. G., Ikura M., The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain Proceedings of the National Academy of Sciences of the United States of America 2006 103 27 10242 10247 (Pubitemid 44051151)
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.27 , pp. 10242-10247
    • Plevin, M.J.1    Zhang, J.2    Guo, C.3    Roeder, R.G.4    Ikura, M.5
  • 61
    • 2942612214 scopus 로고    scopus 로고
    • ETO interacting proteins
    • DOI 10.1038/sj.onc.1207674
    • Hug B. A., Lazar M. A., ETO interacting proteins Oncogene 2004 23 24 4270 4274 (Pubitemid 38758594)
    • (2004) Oncogene , vol.23 , Issue.24 , pp. 4270-4274
    • Hug, B.A.1    Lazar, M.A.2
  • 62
    • 70350521699 scopus 로고    scopus 로고
    • Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network
    • Zaidi S. K., Dowdy C. R., Van Wijnen A. J., Lian J. B., Raza A., Stein J. L., Croce C. M., Stein G. S., Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network Cancer Research 2009 69 21 8249 8255
    • (2009) Cancer Research , vol.69 , Issue.21 , pp. 8249-8255
    • Zaidi, S.K.1    Dowdy, C.R.2    Van Wijnen, A.J.3    Lian, J.B.4    Raza, A.5    Stein, J.L.6    Croce, C.M.7    Stein, G.S.8
  • 63
    • 21044450858 scopus 로고    scopus 로고
    • The t(8;21) translocation converts AML1 into a constitutive transcriptional repressor
    • DOI 10.1242/dev.01824
    • Wildonger J., Mann R. S., The t(8;21) translocation converts AML1 into a constitutive transcriptional repressor Development 2005 132 10 2263 2272 (Pubitemid 40872797)
    • (2005) Development , vol.132 , Issue.10 , pp. 2263-2272
    • Wildonger, J.1    Mann, R.S.2
  • 64
    • 33745624285 scopus 로고    scopus 로고
    • Decreased intranuclear mobility of acute myeloid leukemia 1-containing fusion proteins is accompanied by reduced mobility and compartmentalization of core binding factor β
    • DOI 10.1038/sj.onc.1209431, PII 1209431
    • Qiu J., Wong J., Tweardy D. J., Dong S., Decreased intranuclear mobility of acute myeloid leukemia 1-containing fusion proteins is accompanied by reduced mobility and compartmentalization of core binding factor Oncogene 2006 25 28 3982 3993 (Pubitemid 43990754)
    • (2006) Oncogene , vol.25 , Issue.28 , pp. 3982-3993
    • Qiu, J.1    Wong, J.2    Tweardy, D.J.3    Dong, S.4
  • 65
    • 50049102936 scopus 로고    scopus 로고
    • Identification and characterization of novel AML1-ETO fusion transcripts in pediatric t(8;21) acute myeloid leukemia: A report from the Children's Oncology Group
    • Lafiura K. M., Edwards H., Taub J. W., Matherly L. H., Fontana J. A., Mohamed A. N., Ravindranath Y., Ge Y., Identification and characterization of novel AML1-ETO fusion transcripts in pediatric t(8;21) acute myeloid leukemia: a report from the Children's Oncology Group Oncogene 2008 27 36 4933 4942
    • (2008) Oncogene , vol.27 , Issue.36 , pp. 4933-4942
    • Lafiura, K.M.1    Edwards, H.2    Taub, J.W.3    Matherly, L.H.4    Fontana, J.A.5    Mohamed, A.N.6    Ravindranath, Y.7    Ge, Y.8
  • 67
    • 59649122714 scopus 로고    scopus 로고
    • RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis
    • Yan M., Ahn E. Y., Hiebert S. W., Zhang D. E., RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis Blood 2009 113 4 883 886
    • (2009) Blood , vol.113 , Issue.4 , pp. 883-886
    • Yan, M.1    Ahn, E.Y.2    Hiebert, S.W.3    Zhang, D.E.4
  • 68
    • 79959340296 scopus 로고    scopus 로고
    • Characterisation of AML1-ETO9A leukaemiogenesis using an inducible murine model
    • abstract no 0025
    • Tsoulaki O., Lacaudand G., Kouskoff V., Characterisation of AML1-ETO9A leukaemiogenesis using an inducible murine model Haematologica 2010 95 s2. abstract no 0025
    • (2010) Haematologica , vol.95 , Issue.S2
    • Tsoulaki, O.1    Lacaudand, G.2    Kouskoff, V.3
  • 69
    • 16844375019 scopus 로고    scopus 로고
    • MYND-less splice variants of AML1-MTG8 (RUNX1=CBFA2T1) are expressed in leukemia with t(8;21)
    • DOI 10.1002/gcc.20165
    • Kozu T., Fukuyama T., Yamami T., Akagi K., Kaneko Y., MYND-less splice variants of AML1-MTG8 (RUNX1-CBFA2T1) are expressed in leukemia with t(8;21) Genes Chromosomes and Cancer 2005 43 1 45 53 (Pubitemid 40490354)
    • (2005) Genes Chromosomes and Cancer , vol.43 , Issue.1 , pp. 45-53
    • Kozu, T.1    Fukuyama, T.2    Yamami, T.3    Akagi, K.4    Kaneko, Y.5
  • 70
    • 77950944035 scopus 로고    scopus 로고
    • A novel exon in AML1-ETO negatively influences the clonogenic potential of the t(8;21) in acute myeloid leukemia
    • Mannari D., Gascoyne D., Dunne J., Chaplin T., Young B., A novel exon in AML1-ETO negatively influences the clonogenic potential of the t(8;21) in acute myeloid leukemia Leukemia 2010 24 4 891 894
    • (2010) Leukemia , vol.24 , Issue.4 , pp. 891-894
    • Mannari, D.1    Gascoyne, D.2    Dunne, J.3    Chaplin, T.4    Young, B.5
  • 78
    • 77956942570 scopus 로고    scopus 로고
    • Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity
    • Corpora T., Roudaia L., Oo M., Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity Journal of Molecular Biology 2010 402 3 560 577
    • (2010) Journal of Molecular Biology , vol.402 , Issue.3 , pp. 560-577
    • Corpora, T.1    Roudaia, L.2    Oo, M.3
  • 79
    • 65149092831 scopus 로고    scopus 로고
    • Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity
    • Park S., Chen W., Cierpicki T., Tonelli M., Cai X., Speck N. A., Bushweller J. H., Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity Blood 2009 113 15 3558 3567
    • (2009) Blood , vol.113 , Issue.15 , pp. 3558-3567
    • Park, S.1    Chen, W.2    Cierpicki, T.3    Tonelli, M.4    Cai, X.5    Speck, N.A.6    Bushweller, J.H.7
  • 80
    • 3042701540 scopus 로고    scopus 로고
    • AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation
    • DOI 10.1158/0008-5472.CAN-03-3689
    • Ibaez V., Sharma A., Buonamici S., Verma A., Kalakonda S., Wang J., Kadkol S., Saunthararajah Y., AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation Cancer Research 2004 64 13 4547 4554 (Pubitemid 38856927)
    • (2004) Cancer Research , vol.64 , Issue.13 , pp. 4547-4554
    • Ibanez, V.1    Sharma, A.2    Buonamici, S.3    Verma, A.4    Kalakonda, S.5    Wang, J.6    Kadkol, S.7    Saunthararajah, Y.8
  • 81
    • 33947277861 scopus 로고    scopus 로고
    • Targeting the oligomerization domain of ETO interferes with RUNX1/ETO oncogenic activity in t(8;21)-positive leukemic cells
    • DOI 10.1158/0008-5472.CAN-06-3360
    • Wichmann C., Chen L., Heinrich M., Baus D., Pfitzner E., Zrnig M., Ottmann O. G., Grez M., Targeting the oligomerization domain of ETO interferes with RUNX1/ETO oncogenic activity in t(8;21)-positive leukemic cells Cancer Research 2007 67 5 2280 2289 (Pubitemid 46424248)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 2280-2289
    • Wichmann, C.1    Chen, L.2    Heinrich, M.3    Baus, D.4    Pfitzner, E.5    Zornig, M.6    Ottmann, O.G.7    Grez, M.8
  • 82
    • 0037222293 scopus 로고    scopus 로고
    • The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia
    • DOI 10.1182/blood-2002-04-1288
    • Vangala R. K., Heiss-Neumann M. S., Rangatia J. S., Singh S. M., Schoch C., Tenen D. G., Hiddemann W., Behre G., The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia Blood 2003 101 1 270 277 (Pubitemid 36025918)
    • (2003) Blood , vol.101 , Issue.1 , pp. 270-277
    • Vangala, R.K.1    Heiss-Neumann, M.S.2    Rangatia, J.S.3    Singh, S.M.4    Schoch, C.5    Tenen, D.G.6    Hiddemann, W.7    Behre, G.8
  • 84
    • 0031972701 scopus 로고    scopus 로고
    • The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-α, inhibits C/EBP-α-dependent transcription, and blocks granulocytic differentiation
    • Westendorf J. J., Yamamoto C. M., Lenny N., Downing J. R., Selsted M. E., Hiebert S. W., The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-, inhibits C/EBP- -dependent transcription, and blocks granulocytic differentiation Molecular and Cellular Biology 1998 18 1 322 333 (Pubitemid 28021043)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.1 , pp. 322-333
    • Westendorf, J.J.1    Yamamoto, C.M.2    Lenny, N.3    Downing, J.R.4    Selsted, M.E.5    Hiebert, S.W.6
  • 86
    • 77952430201 scopus 로고    scopus 로고
    • POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature
    • Fortier J. M., Payton J. E., Cahan P., Ley T. J., Walter M. J., Graubert T. A., POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature Leukemia 2010 24 5 950 957
    • (2010) Leukemia , vol.24 , Issue.5 , pp. 950-957
    • Fortier, J.M.1    Payton, J.E.2    Cahan, P.3    Ley, T.J.4    Walter, M.J.5    Graubert, T.A.6
  • 87
    • 5644235305 scopus 로고    scopus 로고
    • PAX5 expression in acute leukemias: Higher B-lineage specificity than CD79a and selective association with t(8;21)-acute myelogenous leukemia
    • DOI 10.1158/0008-5472.CAN-04-1865
    • Tiacci E., Pileri S., Orleth A., Pacini R., Tabarrini A., Frenguelli F., Liso A., Diverio D., Lo-Coco F., Falini B., PAX5 expression in acute leukemias: higher B-lineage specificity than CD79a and selective association with t(8;21)-acute myelogenous leukemia Cancer Research 2004 64 20 7399 7404 (Pubitemid 39372080)
    • (2004) Cancer Research , vol.64 , Issue.20 , pp. 7399-7404
    • Tiacci, E.1    Pileri, S.2    Orleth, A.3    Pacini, R.4    Tabarrini, A.5    Frenguelli, F.6    Liso, A.7    Diverio, D.8    Lo-Coco, F.9    Falini, B.10
  • 88
    • 33746683764 scopus 로고    scopus 로고
    • Expression of B cell-specific activator protein/PAX5 in acute myeloid leukemia with t(8;21)(q22;q22)
    • DOI 10.1309/LG0Q-0VXY-BETJ-4VHE
    • Valbuena J. R., Medeiros L. J., Rassidakis G. Z., Hao S., Wu C. D., Chen L., Lin P., Expression of B cell-specific activator protein/PAX5 in acute myeloid leukemia with t(8;21)(q22;q22) American Journal of Clinical Pathology 2006 126 2 235 240 (Pubitemid 44162570)
    • (2006) American Journal of Clinical Pathology , vol.126 , Issue.2 , pp. 235-240
    • Valbuena, J.R.1    Medeiros, L.J.2    Rassidakis, G.Z.3    Hao, S.4    Wu, C.D.5    Chen, L.6    Lin, P.7
  • 90
    • 34547111816 scopus 로고    scopus 로고
    • Leukemogenic AML1-ETO fusion protein increases carcinogen-DNA adduct formation with upregulated expression of cytochrome P450-1A1 gene
    • DOI 10.1016/j.exphem.2007.04.018, PII S0301472X07002895
    • Xu M., Li D., Lu Y., Chen G. Q., Leukemogenic AML1-ETO fusion protein increases carcinogen-DNA adduct formation with upregulated expression of cytochrome P450-1A1 gene Experimental Hematology 2007 35 8 1249 1255 (Pubitemid 47096757)
    • (2007) Experimental Hematology , vol.35 , Issue.8 , pp. 1249-1255
    • Xu, M.1    Li, D.2    Lu, Y.3    Chen, G.-Q.4
  • 91
    • 41349122682 scopus 로고    scopus 로고
    • P53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death
    • DOI 10.1182/blood-2007-06-093682
    • Krejci O., Wunderlich M., Geiger H., Chou FU. S., Schleimer D., Jansen M., Andreassen P. R., Mulloy J. C., P53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death Blood 2008 111 4 2190 2199 (Pubitemid 351451533)
    • (2008) Blood , vol.111 , Issue.4 , pp. 2190-2199
    • Krejci, O.1    Wunderlich, M.2    Geiger, H.3    Chou, F.-S.4    Schleimer, D.5    Jansen, M.6    Andreassen, P.R.7    Mulloy, J.C.8
  • 92
    • 0029859199 scopus 로고    scopus 로고
    • Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis
    • DOI 10.1073/pnas.93.21.11895
    • Rhoades K. L., Hetherington C. J., Rowley J. D., Hiebert S. W., Nucifora G., Tenen D. G., Zhang D. E., Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis Proceedings of the National Academy of Sciences of the United States of America 1996 93 21 11895 11900 (Pubitemid 26347220)
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.21 , pp. 11895-11900
    • Rhoades, K.L.1    Hetherington, C.J.2    Rowley, J.D.3    Hiebert, S.W.4    Nucifora, G.5    Tenen, D.G.6    Zhang, D.-E.7
  • 93
    • 0034234513 scopus 로고    scopus 로고
    • AML1-MTG8 leukemic protein induces the expression of granulocyte colony- stimulating factor (G-CSF) receptor through the up-regulation of CCAAT/enhancer binding protein epsilon
    • Shimizu K., Kitabayashi I., Kamada N., Abe T., Maseki N., Suzukawa K., Ohki M., AML1-MTG8 leukemic protein induces the expression of granulocyte colony-stimulating factor (G-CSF) receptor through the up-regulation of CCAAT/enhancer binding protein epsilon Blood 2000 96 1 288 296 (Pubitemid 30456484)
    • (2000) Blood , vol.96 , Issue.1 , pp. 288-296
    • Shimizu, K.1    Kitabayashi, I.2    Kamada, N.3    Abe, T.4    Maseki, N.5    Suzukawa, K.6    Ohki, M.7
  • 97
    • 34248325702 scopus 로고    scopus 로고
    • Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO
    • DOI 10.1182/blood-2006-03-012575
    • Peterson L. F., Yan M., Zhang D. E., The p21 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO Blood 2007 109 10 4392 4398 (Pubitemid 46743408)
    • (2007) Blood , vol.109 , Issue.10 , pp. 4392-4398
    • Peterson, L.F.1    Yan, M.2    Zhang, D.-E.3
  • 98
    • 33746494493 scopus 로고    scopus 로고
    • Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: The role in AML 1-ETO-induced growth arrest in leukemic cells
    • DOI 10.1002/jcp.20695
    • Li X. I., Xu Y. A. B., Wang Q., Lu Y., Zheng Y., Wang Y. C., Lbbert M., Zhao K. E. W., Chen G. Q., Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: the role in AML 1-ETO-induced growth arrest in leukemic cells Journal of Cellular Physiology 2006 208 3 594 601 (Pubitemid 44141884)
    • (2006) Journal of Cellular Physiology , vol.208 , Issue.3 , pp. 594-601
    • Li, X.1    Xu, Y.-B.2    Wang, Q.3    Lu, Y.4    Zheng, Y.5    Wang, Y.-C.6    Lubbert, M.7    Zhao, K.-W.8    Chen, G.-Q.9
  • 99
    • 85128447446 scopus 로고    scopus 로고
    • Leukemia associated antigens: Their dual role as biomarkers and immunotherapeutic targets for acute myeloid leukemia
    • Guinn B. A., Mohamedali A., Mills K. I., Leukemia associated antigens: their dual role as biomarkers and immunotherapeutic targets for acute myeloid leukemia Biomark Insights 2007 2 69 79
    • (2007) Biomark Insights , vol.2 , pp. 69-79
    • Guinn, B.A.1    Mohamedali, A.2    Mills, K.I.3
  • 100
    • 34247378186 scopus 로고    scopus 로고
    • Aleukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy
    • DOI 10.1182/blood-2006-09-045583
    • Boyapati A., Yan M., Peterson L. F., Biggs J. R., Le Beau M. M., Zhang D. E., Aleukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy Blood 2007 109 9 3963 3971 (Pubitemid 46641749)
    • (2007) Blood , vol.109 , Issue.9 , pp. 3963-3971
    • Boyapati, A.1    Yan, M.2    Peterson, L.F.3    Biggs, J.R.4    Le Beau, M.M.5    Zhang, D.-E.6
  • 102
    • 33947492471 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase mediates AML1-ETO protein-induced connexin-43 expression
    • DOI 10.1016/j.bbrc.2007.03.009, PII S0006291X07004755
    • Gao F. H., Wang Q., Wu Y. L., Li XI., Zhao KE. W., Chen G. Q., c-Jun N-terminal kinase mediates AML1-ETO protein-induced connexin-43 expression Biochemical and Biophysical Research Communications 2007 356 2 505 511 (Pubitemid 46463947)
    • (2007) Biochemical and Biophysical Research Communications , vol.356 , Issue.2 , pp. 505-511
    • Gao, F.-H.1    Wang, Q.2    Wu, Y.-L.3    Li, X.4    Zhao, K.-W.5    Chen, G.-Q.6
  • 103
    • 67649305166 scopus 로고    scopus 로고
    • The gene encoding thioredoxin-interacting protein (TXNIP) is a frequent virus integration site in virus-induced mouse leukemia and is overexpressed in a subset of AML patients
    • Erkeland S. J., Palande K. K., Valkhof M., Gits J., Oorschot A. D. V., Touw I. P., The gene encoding thioredoxin-interacting protein (TXNIP) is a frequent virus integration site in virus-induced mouse leukemia and is overexpressed in a subset of AML patients Leukemia Research 2009 33 10 1367 1371
    • (2009) Leukemia Research , vol.33 , Issue.10 , pp. 1367-1371
    • Erkeland, S.J.1    Palande, K.K.2    Valkhof, M.3    Gits, J.4    Oorschot, A.D.V.5    Touw, I.P.6
  • 104
    • 32844473277 scopus 로고    scopus 로고
    • ARF expression
    • DOI 10.1016/j.leukres.2005.08.007, PII S0145212605003152
    • Shikami M., Miwa H., Nish K. II, Kyo T., Tanaka I., Shiku H., Kita K., Nitta M., Low p53 expression of acute myelocytic leukemia cells with t(8;21) chromosome abnormality: association with low p14 expression Leukemia Research 2006 30 4 379 383 (Pubitemid 43254958)
    • (2006) Leukemia Research , vol.30 , Issue.4 , pp. 379-383
    • Shikami, M.1    Miwa, H.2    Nishii, K.3    Kyo, T.4    Tanaka, I.5    Shiku, H.6    Kita, K.7    Nitta, M.8
  • 105
    • 78649463826 scopus 로고    scopus 로고
    • Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model
    • Sinenko S. A., Hung T., Moroz T., Tran Q.-M., Sidhu S., Cheney M. D., Speck N. A., Banerjee U., Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model Blood 2010 116 22 4612 4620
    • (2010) Blood , vol.116 , Issue.22 , pp. 4612-4620
    • Sinenko, S.A.1    Hung, T.2    Moroz, T.3    Tran, Q.-M.4    Sidhu, S.5    Cheney, M.D.6    Speck, N.A.7    Banerjee, U.8
  • 106
    • 67651100677 scopus 로고    scopus 로고
    • Connexins are active participants of hematopoietic stem cell regulation
    • Foss B., Hervig T., Bruserud., Connexins are active participants of hematopoietic stem cell regulation Stem Cells and Development 2009 18 6 807 812
    • (2009) Stem Cells and Development , vol.18 , Issue.6 , pp. 807-812
    • Foss, B.1    Hervig, T.2    Bruserud3
  • 107
    • 71749114168 scopus 로고    scopus 로고
    • Connexin-based signaling in acute myelogenous leukemia (AML)
    • Foss B., Tronstad K. J., Bruserud., Connexin-based signaling in acute myelogenous leukemia (AML) Biochimica et Biophysica Acta 2010 1798 1 1 8
    • (2010) Biochimica et Biophysica Acta , vol.1798 , Issue.1 , pp. 1-8
    • Foss, B.1    Tronstad, K.J.2    Bruserud3
  • 108
    • 51649109222 scopus 로고    scopus 로고
    • T(8;21)(q22;q22) fusion proteins preferentially bind to duplicated AML1/RUNX1 DNA-binding sequences to differentially regulate gene expression
    • Okumura A. J., Peterson L. F., Okumura F., Boyapati A., Zhang D. E., T(8;21)(q22;q22) fusion proteins preferentially bind to duplicated AML1/RUNX1 DNA-binding sequences to differentially regulate gene expression Blood 2008 112 4 1392 1401
    • (2008) Blood , vol.112 , Issue.4 , pp. 1392-1401
    • Okumura, A.J.1    Peterson, L.F.2    Okumura, F.3    Boyapati, A.4    Zhang, D.E.5
  • 111
    • 33750873600 scopus 로고    scopus 로고
    • Proteomics of acute myeloid leukaemia: Cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications
    • DOI 10.1038/sj.onc.1209689, PII 1209689
    • Balkhi M. Y., Trivedi A. K., Geletu M., Christopeit M., Bohlander S. K., Behre H. M., Behre G., Proteomics of acute myeloid leukaemia: cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications Oncogene 2006 25 53 7041 7058 (Pubitemid 44722072)
    • (2006) Oncogene , vol.25 , Issue.53 , pp. 7041-7058
    • Balkhi, M.Y.1    Trivedi, A.K.2    Geletu, M.3    Christopeit, M.4    Bohlander, S.K.5    Behre, H.M.6    Behre, G.7
  • 115
    • 33750568635 scopus 로고    scopus 로고
    • T(8;21) acute myeloid leukaemia cells are dependent on vascular endothelial growth factor (VEGF)/VEGF receptor type2 pathway and phosphorylation of Akt
    • DOI 10.1111/j.1365-2141.2006.06372.x
    • Imai N., Shikami M., Miwa H., Suganuma K., Hiramatsu A., Watarai M., Satoh A., Itoh M., Imamura A., Mihara H., Nitta M., t(8;21) acute myeloid leukaemia cells are dependent on vascular endothelial growth factor (VEGF)/VEGF receptor type2 pathway and phosphorylation of Akt British Journal of Haematology 2006 135 5 673 682 (Pubitemid 44674078)
    • (2006) British Journal of Haematology , vol.135 , Issue.5 , pp. 673-682
    • Imai, N.1    Shikami, M.2    Miwa, H.3    Suganuma, K.4    Hiramatsu, A.5    Watarai, M.6    Satoh, A.7    Itoh, M.8    Imamura, A.9    Mihara, H.10    Nitta, M.11
  • 117
    • 79959356519 scopus 로고    scopus 로고
    • Future perspectives: Therapeutic targeting of NOTCH signalling may become a strategy in patients receiving stem cell transplantation for hematologic malignancies
    • Ersvaer E., Hatfield K., Reikvam H., Bruserud O., Future perspectives: therapeutic targeting of NOTCH signalling may become a strategy in patients receiving stem cell transplantation for hematologic malignancies Bone Marrow Research 2011 2011
    • (2011) Bone Marrow Research , vol.2011
    • Ersvaer, E.1    Hatfield, K.2    Reikvam, H.3    Bruserud, O.4
  • 122
    • 17744385958 scopus 로고    scopus 로고
    • Comparison of outcome in acute myelogenous leukemia patients with translocation (8;21) found by standard cytogenetic analysis and patients with AML1/ETO fusion transcript found only by PCR testing
    • DOI 10.1038/sj.leu.2401951
    • Sarriera J. E., Albitar M., Estrov Z., Gidel C., Aboul-Na R. Sr., Manshouri T., Kornblau S., Chang K. S., Kantarjian H., Estey E., Comparison of outcome in acute myelogenous leukemia patients with translocation (8;21) found by standard cytogenetic analysis and patients with AML1/ETO fusion transcript found only by PCR testing Leukemia 2001 15 1 57 61 (Pubitemid 32124069)
    • (2001) Leukemia , vol.15 , Issue.1 , pp. 57-61
    • Sarriera, J.E.1    Albitar, M.2    Estrov, Z.3    Gidel, C.4    Aboul-Nasr, R.5    Manshouri, T.6    Kornblau, S.7    Chang, K.-S.8    Kantarjian, H.9    Estey, E.10
  • 126
    • 0033830630 scopus 로고    scopus 로고
    • New strategies in the treatment of acute myelogenous leukemia: Mobilization and transplantation of autologous peripheral blood stem cells in adult patients
    • Bruserud., Tjnnfjord G., Gjertsen B. T., Foss B., Ernst P., New strategies in the treatment of acute myelogenous leukemia: mobilization and transplantation of autologous peripheral blood stem cells in adult patients Stem Cells 2000 18 5 343 351
    • (2000) Stem Cells , vol.18 , Issue.5 , pp. 343-351
    • Bruserud1    Tjnnfjord, G.2    Gjertsen, B.T.3    Foss, B.4    Ernst, P.5
  • 127
    • 85047697180 scopus 로고    scopus 로고
    • Diagnostic detection of AML1/ETO gene fusion by polymerase chain reaction
    • Rowe D., Bown N. P., Albitar M., Estey E., Diagnostic detection of AML1/ETO gene fusion by polymerase chain reaction Leukemia 2002 16 8 1576 1577
    • (2002) Leukemia , vol.16 , Issue.8 , pp. 1576-1577
    • Rowe, D.1    Bown, N.P.2    Albitar, M.3    Estey, E.4
  • 130
    • 33645468216 scopus 로고    scopus 로고
    • Diagnosis and monitoring of AML1-MTG8 (ETO)-positive acute myeloid leukemia by qualitative and real-time quantitative RT-PCR
    • Tobal K., Liu Yin J. A., Diagnosis and monitoring of AML1-MTG8 (ETO)-positive acute myeloid leukemia by qualitative and real-time quantitative RT-PCR Methods in molecular medicine. 2006 125 149 161
    • (2006) Methods in Molecular Medicine. , vol.125 , pp. 149-161
    • Tobal, K.1    Liu Yin, J.A.2
  • 131
  • 132
    • 0032528339 scopus 로고    scopus 로고
    • Multiplex reverse transcription-polymerase chain reaction for simultaneous screening of 29 translocations and chromosomal aberrations in acute leukemia
    • Pallisgaard N., Hokland P., Riishj D. C., Pedersen B., Jrgensen P., Multiplex reverse transcription-polymerase chain reaction for simultaneous screening of 29 translocations and chromosomal aberrations in acute leukemia Blood 1998 92 2 574 588 (Pubitemid 28323721)
    • (1998) Blood , vol.92 , Issue.2 , pp. 574-588
    • Pallisgaard, N.1    Hokland, P.2    Riishoj, D.C.3    Pedersen, B.4    Jorgensen, P.5
  • 133
    • 3543057678 scopus 로고    scopus 로고
    • Granulocytic sarcoma presenting as pneumonia in a child with t(8;21) acute myelogenous leukemia: Diagnosis by flourescent in situ hybridization
    • DOI 10.1097/00043426-200407000-00006
    • Lee D. A., Harris C. P., Gresik V. M., Rao P., Lau C. C., Granulocytic sarcoma presenting as pneumonia in a child with t(8;21) acute myelogenous leukemia: diagnosis by flourescent in situ hybridization Journal of Pediatric Hematology/Oncology 2004 26 7 431 434 (Pubitemid 39025255)
    • (2004) Journal of Pediatric Hematology/Oncology , vol.26 , Issue.7 , pp. 431-434
    • Lee, D.A.1    Harris, C.P.2    Gresik, V.M.3    Rao, P.4    Lau, C.C.5
  • 134
    • 0031052164 scopus 로고    scopus 로고
    • Presence of t(8;21)(q22;q22) in myeloperoxidase-positive, myeloid surface antigen-negative acute myeloid leukemia
    • Arber D. A., Glackin C., Lowe G., Medeiros L. J., Slovak M. L., Presence of t(8;21)(q22;q22) in myeloperoxidase-positive, myeloid surface antigen-negative acute myeloid leukemia American Journal of Clinical Pathology 1997 107 1 68 73 (Pubitemid 27104639)
    • (1997) American Journal of Clinical Pathology , vol.107 , Issue.1 , pp. 68-73
    • Arber, D.A.1    Glackin, C.2    Lowe, G.3    Medeiros, L.J.4    Slovak, M.L.5
  • 136
    • 35348858918 scopus 로고    scopus 로고
    • Immunophenotypic profile predictive off KIT activating mutations in AML1-ETO leukemia
    • DOI 10.1309/JVALJNL4ELQMD536
    • De J., Zanjani R., Hibbard M., Davis B. H., Immunophenotypic profile predictive off KIT activating mutations in AML1-ETO leukemia American Journal of Clinical Pathology 2007 128 4 550 557 (Pubitemid 47584431)
    • (2007) American Journal of Clinical Pathology , vol.128 , Issue.4 , pp. 550-557
    • De, J.1    Zanjani, R.2    Hibbard, M.3    Davis, B.H.4
  • 138
    • 0019490812 scopus 로고
    • Granulocytic sarcoma: A clinicopathologic study of 61 biopsied cases
    • DOI 10.1002/1097-0142(19810915)48:6<1426::AID-CNCR2820480626>3.0. CO;2-G
    • Neiman R. S., Barcos M., Berard C., Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases Cancer 1981 48 6 1426 1437 (Pubitemid 11042596)
    • (1981) Cancer , vol.48 , Issue.6 , pp. 1426-1437
    • Neiman, R.S.1    Barcos, M.2    Berard, C.3
  • 139
    • 0032836835 scopus 로고    scopus 로고
    • An unusual case of intrapulmonary granulocytic sarcoma presenting as interstitial pneumonitis following allogeneic bone marrow transplantation for acute myeloid leukaemia and responding to donor lymphocyte infusion
    • Kottaridis P. D., Ketley N., Peggs K., Chakraverty R., Ralleigh G., Shaw P., Pezzella F., Goldstone A. H., Devereux S., Mackinnon S., An unusual case of intrapulmonary granulocytic sarcoma presenting as interstitial pneumonitis following allogeneic bone marrow transplantation for acute myeloid leukaemia and responding to donor lymphocyte infusion Bone Marrow Transplantation 1999 24 7 807 809 (Pubitemid 29469284)
    • (1999) Bone Marrow Transplantation , vol.24 , Issue.7 , pp. 807-809
    • Kottaridis, P.D.1    Ketley, N.2    Peggs, K.3    Chakraverty, R.4    Ralleigh, G.5    Shaw, P.6    Pezzella, F.7    Goldstone, A.H.8    Devereux, S.9    Mackinnon, S.10
  • 143
    • 58949086993 scopus 로고    scopus 로고
    • Granulocytic sarcoma causing cord compression in a pregnant woman with acute myeloid leukemia and t(8;21)
    • Al-Sobbi E. M., Jeha T. M., Al-Taher M. I., Granulocytic sarcoma causing cord compression in a pregnant woman with acute myeloid leukemia and t(8;21) Saudi Medical Journal 2008 29 11 1658 1661
    • (2008) Saudi Medical Journal , vol.29 , Issue.11 , pp. 1658-1661
    • Al-Sobbi, E.M.1    Jeha, T.M.2    Al-Taher, M.I.3
  • 144
    • 60149100276 scopus 로고    scopus 로고
    • Molecular detection of AML1-MTG8-positive cells in peripheral blood from a patient with isolated extramedullary relapse of t(8;21) acute myeloid leukemia
    • Tamaki H., Yoshihara S., Fujioka T., Kawakami M., Oka Y., Ogawa H., Molecular detection of AML1-MTG8-positive cells in peripheral blood from a patient with isolated extramedullary relapse of t(8;21) acute myeloid leukemia Leukemia 2009 23 2 424 426
    • (2009) Leukemia , vol.23 , Issue.2 , pp. 424-426
    • Tamaki, H.1    Yoshihara, S.2    Fujioka, T.3    Kawakami, M.4    Oka, Y.5    Ogawa, H.6
  • 145
    • 67749116238 scopus 로고    scopus 로고
    • Aleukaemic acute myeloid leukaemia with t(8;21)(q22;q22): Images in haematology
    • Wong K. F., Siu L. L. P., Wong W. S., Aleukaemic acute myeloid leukaemia with t(8;21)(q22;q22): images in haematology British Journal of Haematology 2009 146 4 345
    • (2009) British Journal of Haematology , vol.146 , Issue.4 , pp. 345
    • Wong, K.F.1    Siu, L.L.P.2    Wong, W.S.3
  • 146
    • 32144437602 scopus 로고    scopus 로고
    • Heart and muscle involvement by extra-medullary myeloid leukemia: A case report and review of the literature
    • DOI 10.1080/10428190500233830, PII X53X541296181
    • Jost E., Lorenzen J., Haage P., Bos G., Beelen D., Galm O., Gehbauer G., Osieka R., Heart and muscle involvement by extra-medullary myeloid leukemia: a case report and review of the literature Leukemia and Lymphoma 2005 46 12 1819 1824 (Pubitemid 43203119)
    • (2005) Leukemia and Lymphoma , vol.46 , Issue.12 , pp. 1819-1824
    • Jost, E.1    Lorenzen, J.2    Haage, P.3    Bos, G.4    Beelen, D.5    Galm, O.6    Gehbauer, G.7    Osieka, R.8
  • 147
    • 0034655224 scopus 로고    scopus 로고
    • Good outcome of children with acute myeloid leukemia and t(8;21)(q22;q22), even when associated with granulocytic sarcoma: A report from a single institution in Argentina
    • DOI 10.1002/(SICI)1097-0142(20000415)88:8<1939::AID-CNCR24>3.0. CO;2-Z
    • Felice M. S., Zubizarreta P. A., Alfaro E. M., Gallego M. S., Cygler A. M., Rosso D. A., Rossi J. G., Sackmann-Muriel F., Good outcome of children with acute myeloid leukemia and t(8;21)(q22;q22), even when associated with granulocytic sarcoma: a report from a single institution in Argentina Cancer 2000 88 8 1939 1944 (Pubitemid 30213005)
    • (2000) Cancer , vol.88 , Issue.8 , pp. 1939-1944
    • Felice, M.S.1    Zubizarreta, P.A.2    Alfaro, E.M.3    Gallego, M.S.4    Cygler, A.M.5    Rosso, D.A.6    Rossi, J.G.7    Sackmann-Muriel, F.8
  • 148
    • 79959362120 scopus 로고    scopus 로고
    • Systemic mastocytosis associated with t(8;21)(q22;q22) acute myeloid leukemia
    • Pullarkat S. T., Pullarkat V., Kroft S. H., Systemic mastocytosis associated with t(8;21)(q22;q22) acute myeloid leukemia Journal of Hematopathology 2009 2 1 27 33
    • (2009) Journal of Hematopathology , vol.2 , Issue.1 , pp. 27-33
    • Pullarkat, S.T.1    Pullarkat, V.2    Kroft, S.H.3
  • 149
    • 33845193026 scopus 로고    scopus 로고
    • Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic clone
    • DOI 10.1016/j.leukres.2006.03.006, PII S0145212606001019
    • Pullarkat V., Bedell V., Kim Y., Bhatia R., Nakamura R., Forman S., Sun J., Senitzer D., Slovak M. L., Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic clone Leukemia Research 2007 31 2 261 265 (Pubitemid 44854181)
    • (2007) Leukemia Research , vol.31 , Issue.2 , pp. 261-265
    • Pullarkat, V.1    Bedell, V.2    Kim, Y.3    Bhatia, R.4    Nakamura, R.5    Forman, S.6    Sun, J.7    Senitzer, D.8    Slovak, M.L.9
  • 151
    • 41949119129 scopus 로고    scopus 로고
    • Systemic mastocytosis with plasma cell dyscrasia: Report of a case
    • DOI 10.1016/j.leukres.2007.10.017, PII S0145212607004079
    • Pullarkat S. T., Sedarat F., Paquette R., Said J., Systemic mastocytosis with plasma cell dyscrasia: report of a case Leukemia Research 2008 32 7 1160 1163 (Pubitemid 351514789)
    • (2008) Leukemia Research , vol.32 , Issue.7 , pp. 1160-1163
    • Pullarkat, S.T.1    Sedarat, F.2    Paquette, R.3    Said, J.4
  • 153
    • 45549092335 scopus 로고    scopus 로고
    • Review: Genetic models of acute myeloid leukaemia
    • DOI 10.1038/onc.2008.16, PII ONC200816
    • McCormack E., Bruserud O., Gjertsen B. T., Review: genetic models of acute myeloid leukaemia Oncogene 2008 27 27 3765 3779 (Pubitemid 351862057)
    • (2008) Oncogene , vol.27 , Issue.27 , pp. 3765-3779
    • McCormack, E.1    Bruserud, O.2    Gjertsen, B.T.3
  • 156
    • 77949715448 scopus 로고    scopus 로고
    • Integrative meta-analysis of differential gene expression in acute myeloid leukemia
    • Miller B. G., Stamatoyannopoulos J. A., Integrative meta-analysis of differential gene expression in acute myeloid leukemia PLoS ONE 2010 5
    • (2010) PLoS ONE , vol.5
    • Miller, B.G.1    Stamatoyannopoulos, J.A.2
  • 159
    • 70349289739 scopus 로고    scopus 로고
    • Nuclear factor-B signaling: A contributor in leukemogenesis and a target for pharmacological intervention in human acute myelogenous leukemia
    • Reikvam H., Olsnes A. M., Gjertsen B. T., Ersvar E., Bruserud O., Nuclear factor-B signaling: a contributor in leukemogenesis and a target for pharmacological intervention in human acute myelogenous leukemia Critical Reviews in Oncogenesis 2009 15 1-2 1 41
    • (2009) Critical Reviews in Oncogenesis , vol.15 , Issue.12 , pp. 1-41
    • Reikvam, H.1    Olsnes, A.M.2    Gjertsen, B.T.3    Ersvar, E.4    Bruserud, O.5
  • 161
    • 77957021519 scopus 로고    scopus 로고
    • Pharmacological targeting of the PI3K-AKT/PKB-mTOR pathway alters local angioregulation in acute myelogenous leukemia
    • abstract no 0634
    • Reikvam H., Hatfield K., Ersvaer E., Ryningen A., Bruserud., Pharmacological targeting of the PI3K-AKT/PKB-mTOR pathway alters local angioregulation in acute myelogenous leukemia Haematologica 2010 95 s2. abstract no 0634
    • (2010) Haematologica , vol.95 , Issue.S2
    • Reikvam, H.1    Hatfield, K.2    Ersvaer, E.3    Ryningen, A.4    Bruserud5
  • 162
    • 34547202520 scopus 로고    scopus 로고
    • Targeting receptor tyrosine kinase signaling in acute myeloid leukemia
    • DOI 10.1016/j.critrevonc.2007.05.005, PII S1040842807001102
    • Doepfner K. T., Boller D., Arcaro A., Targeting receptor tyrosine kinase signaling in acute myeloid leukemia Critical Reviews in Oncology/Hematology 2007 63 3 215 230 (Pubitemid 47126864)
    • (2007) Critical Reviews in Oncology/Hematology , vol.63 , Issue.3 , pp. 215-230
    • Doepfner, K.T.1    Boller, D.2    Arcaro, A.3
  • 163
    • 23244435090 scopus 로고    scopus 로고
    • PRAME mRNA levels in cases with acute leukemia: Clinical importance and future prospects
    • DOI 10.1002/ajh.20425
    • Paydas S., Tanriverdi K., Yavuz S., Disel U., Baslamisli F., Burgut R., PRAME mRNA levels in cases with acute leukemia: clinical importance and future prospects American Journal of Hematology 2005 79 4 257 261 (Pubitemid 41098836)
    • (2005) American Journal of Hematology , vol.79 , Issue.4 , pp. 257-261
    • Paydas, S.1    Tanriverdi, K.2    Yavuz, S.3    Disel, U.4    Baslamisli, F.5    Burgut, R.6
  • 164
    • 77954560509 scopus 로고    scopus 로고
    • Combination of intensive chemotherapy and anticancer vaccines in the treatment of human malignancies: The hematological experience
    • Liseth K., Ersvaer E., Hervig T., Bruserud., Combination of intensive chemotherapy and anticancer vaccines in the treatment of human malignancies: the hematological experience Journal of Biomedicine and Biotechnology 2010 2010
    • (2010) Journal of Biomedicine and Biotechnology , vol.2010
    • Liseth, K.1    Ersvaer, E.2    Hervig, T.3    Bruserud4
  • 165
    • 3242699515 scopus 로고    scopus 로고
    • Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow
    • DOI 10.1016/j.leukres.2004.01.010, PII S0145212604000414
    • Pang A., Au W. Y., Kwong Y. L., Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow Leukemia Research 2004 28 9 973 977 (Pubitemid 38953652)
    • (2004) Leukemia Research , vol.28 , Issue.9 , pp. 973-977
    • Pang, A.1    Au, W.Y.2    Kwong, Y.L.3
  • 166
    • 58149196159 scopus 로고    scopus 로고
    • Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs
    • Stoeckle C., Gouttefangeas C., Hammer M., Weber E., Melms A., Tolosa E., Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs Experimental Hematology 2009 37 2 266 275
    • (2009) Experimental Hematology , vol.37 , Issue.2 , pp. 266-275
    • Stoeckle, C.1    Gouttefangeas, C.2    Hammer, M.3    Weber, E.4    Melms, A.5    Tolosa, E.6
  • 167
    • 23444443067 scopus 로고
    • Activation of the leukocyte plastin gene occurs in most human cancer cells
    • Park T., Zong Ping Chen., Leavitt J., Activation of the leukocyte plastin gene occurs in most human cancer cells Cancer Research 1994 54 7 1775 1781 (Pubitemid 24116185)
    • (1994) Cancer Research , vol.54 , Issue.7 , pp. 1775-1781
    • Park, T.1    Chen, Z.P.2    Leavitt, J.3
  • 169
    • 47949102937 scopus 로고    scopus 로고
    • The semaphorins: Versatile regulators of tumour progression and tumour angiogenesis
    • Neufeld G., Kessler O., The semaphorins: versatile regulators of tumour progression and tumour angiogenesis Nature Reviews Cancer 2008 8 8 632 645
    • (2008) Nature Reviews Cancer , vol.8 , Issue.8 , pp. 632-645
    • Neufeld, G.1    Kessler, O.2
  • 170
    • 46749108531 scopus 로고    scopus 로고
    • MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia
    • Jongen-Lavrencic M., Sun S. U. M., Dijkstra M. K., Valk P. J. M., Lwenberg B., MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia Blood 2008 111 10 5078 5085
    • (2008) Blood , vol.111 , Issue.10 , pp. 5078-5085
    • Jongen-Lavrencic, M.1    Sun, S.U.M.2    Dijkstra, M.K.3    Valk, P.J.M.4    Lwenberg, B.5
  • 173
    • 40849139208 scopus 로고    scopus 로고
    • Molecular origins of cancer: Epigenetics in cancer
    • Esteller M., Molecular origins of cancer: epigenetics in cancer The New England Journal of Medicine 2008 358 11 1148 1096
    • (2008) The New England Journal of Medicine , vol.358 , Issue.11 , pp. 1148-1096
    • Esteller, M.1
  • 179
    • 48749106371 scopus 로고    scopus 로고
    • Acute myeloid leukemia harboring t(8;21)(q22;q22): A heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations
    • Lin P., Chen L., Luthra R., Konoplev S. N., Wang X., Medeiros L. J., Acute myeloid leukemia harboring t(8;21)(q22;q22): a heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations Modern Pathology 2008 21 8 1029 1036
    • (2008) Modern Pathology , vol.21 , Issue.8 , pp. 1029-1036
    • Lin, P.1    Chen, L.2    Luthra, R.3    Konoplev, S.N.4    Wang, X.5    Medeiros, L.J.6
  • 182
    • 79959333457 scopus 로고    scopus 로고
    • Bone marrow cellularity is a single most important independent prognostic factor in AML patients with t(8;21)
    • abstract no 1707
    • Shin H.-J., Chung J., Kim H. J., Bone marrow cellularity is a single most important independent prognostic factor in AML patients with t(8;21) ASH Annual Meeting Abstracts 2010 116 21. abstract no 1707
    • (2010) ASH Annual Meeting Abstracts , vol.116 , Issue.21
    • Shin, H.-J.1    Chung, J.2    Kim, H.J.3
  • 185
    • 28544445097 scopus 로고    scopus 로고
    • Long-term results of children with acute myeloid leukemia: A report of three consecutive Phase III trials by the Children's Cancer Group: CCG 251, CCG 213 and CCG 2891
    • DOI 10.1038/sj.leu.2403925, PII 2403925
    • Smith F. O., Alonzo T. A., Gerbing R. B., Woods W. G., Arceci R. J., Long-term results of children with acute myeloid leukemia: a report of three consecutive Phase III trials by the Children's Cancer Group: CCG 251, CCG 213 and CCG 2891 Leukemia 2005 19 12 2054 2062 (Pubitemid 41741597)
    • (2005) Leukemia , vol.19 , Issue.12 , pp. 2054-2062
    • Smith, F.O.1    Alonzo, T.A.2    Gerbing, R.B.3    Woods, W.G.4    Arceci, R.J.5
  • 188
    • 49249096735 scopus 로고    scopus 로고
    • Identical outcome after autologous or allogeneic genoidentical hematopoietic stem-cell transplantation in first remission of acute myelocytic leukemia carrying inversion 16 or t(8;21): A retrospective study from the European Cooperative Group for Blood and Marrow Transplantation
    • Gorin N.-C., Labopin M., Frassoni F., Milpied N., Attal M., Blaise D., Meloni G., Iori A. P., Michallet M., Willemze R., Deconninck E., Harousseau J.-L., Polge E., Rocha V., Identical outcome after autologous or allogeneic genoidentical hematopoietic stem-cell transplantation in first remission of acute myelocytic leukemia carrying inversion 16 or t(8;21): a retrospective study from the European Cooperative Group for Blood and Marrow Transplantation Journal of Clinical Oncology 2008 26 19 3183 3188
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.19 , pp. 3183-3188
    • Gorin, N.-C.1    Labopin, M.2    Frassoni, F.3    Milpied, N.4    Attal, M.5    Blaise, D.6    Meloni, G.7    Iori, A.P.8    Michallet, M.9    Willemze, R.10    Deconninck, E.11    Harousseau, J.-L.12    Polge, E.13    Rocha, V.14
  • 191
    • 79955036651 scopus 로고    scopus 로고
    • New prognostic markers in acute myeloid leukemia: Perspective from the clinic
    • Foran J. M., New prognostic markers in acute myeloid leukemia: perspective from the clinic Hematology American Society of Hematology Education Program 2010 2010 1 47 55
    • (2010) Hematology American Society of Hematology Education Program , vol.2010 , Issue.1 , pp. 47-55
    • Foran, J.M.1
  • 192
    • 37249071337 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer treatment: A review of the clinical toxicity and the modulation of gene expression in cancer cells
    • DOI 10.2174/138920107783018417
    • Bruserud., Stapnes C., Ersvr E., Gjertsen B. T., Ryningen A., Histone deacetylase inhibitors in cancer treatment: a review of the clinical toxicity and the modulation of gene expression in cancer cells Current Pharmaceutical Biotechnology 2007 8 6 388 400 (Pubitemid 350268198)
    • (2007) Current Pharmaceutical Biotechnology , vol.8 , Issue.6 , pp. 388-400
    • Bruserud, O.1    Stapnes, C.2    Ersvaer, E.3    Gjertsen, B.T.4    Ryningen, A.5
  • 194
    • 0036161366 scopus 로고    scopus 로고
    • 2a subtype
    • Chen Z., Wang Y., Wang W., Gong J., Xue Y., All-trans retinoic acid as a single agent induces complete remission in a patient with acute leukemia of M subtype Chinese Medical Journal 2002 115 1 58 61 (Pubitemid 34130437)
    • (2002) Chinese Medical Journal , vol.115 , Issue.1 , pp. 58-61
    • Chen, Z.1    Wang, Y.2    Wang, W.3    Gong, J.4    Xue, Y.5
  • 196
  • 197
    • 9344257318 scopus 로고    scopus 로고
    • Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia
    • Miyamoto T., Nagafuji K., Akashi K., Harada M., Kyo T., Akashi T., Takenaka K., Mizuno S. I., Gondo H., Okamura T., Dohy H., Niho Y., Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia Blood 1996 87 11 4789 4796 (Pubitemid 26162380)
    • (1996) Blood , vol.87 , Issue.11 , pp. 4789-4796
    • Miyamoto, T.1    Nagafuji, K.2    Akashi, K.3    Harada, M.4    Kyo, T.5    Akashi, T.6    Takenaka, K.7    Mizuno, S.-I.8    Gondo, H.9    Okamura, T.10    Dohy, H.11    Niho, Y.12
  • 198
    • 0027317604 scopus 로고
    • Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission
    • Nucifora G., Larson R. A., Rowley J. D., Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission Blood 1993 82 3 712 715 (Pubitemid 23221647)
    • (1993) Blood , vol.82 , Issue.3 , pp. 712-715
    • Nucifora, G.1    Larson, R.A.2    Rowley, J.D.3
  • 199
    • 0028596058 scopus 로고
    • Detection of t(8;21) by reverse transcriptase polymerase chain reaction in patients in remission of acute myeloid leukaemia type M2 after chemotherapy or bone marrow transplantation
    • Saunders M. J., Tobal K., Liu Yin J. A., Detection of t(8;21) by reverse transcriptase polymerase chain reaction in patients in remission of acute myeloid leukaemia type M2 after chemotherapy or bone marrow transplantation Leukemia Research 1994 18 12 891 895
    • (1994) Leukemia Research , vol.18 , Issue.12 , pp. 891-895
    • Saunders, M.J.1    Tobal, K.2    Liu Yin, J.A.3
  • 201
    • 0141923916 scopus 로고    scopus 로고
    • + acute myeloid leukemia based on quantification of fusion transcripts
    • DOI 10.1182/blood-2003-03-0880
    • Schnittger S., Weisser M., Schoch C., Hiddemann W., Haferlach T., Kern W., New score predicting for prognosis in PML-RARA+, AML1-ETO+, or CBFB-MYH11 acute myeloid leukemia based on quantification of fusion transcripts Blood 2003 102 8 2746 2755 (Pubitemid 37248843)
    • (2003) Blood , vol.102 , Issue.8 , pp. 2746-2755
    • Schnittger, S.1    Weisser, M.2    Schoch, C.3    Hiddemann, W.4    Haferlach, T.5    Kern, W.6
  • 203
    • 75649091203 scopus 로고    scopus 로고
    • Strikingly different molecular relapse kinetics in NPM1c, PML-RARA, RUNX1-RUNX1T1, and CBFB-MYH11 acute myeloid leukemias
    • Ommen H. B., Schnittger S., Jovanovic J. V., Ommen I. B., Hasle H., stergaard M., Grimwade D., Hokland P., Strikingly different molecular relapse kinetics in NPM1c, PML-RARA, RUNX1-RUNX1T1, and CBFB-MYH11 acute myeloid leukemias Blood 2010 115 2 198 205
    • (2010) Blood , vol.115 , Issue.2 , pp. 198-205
    • Ommen, H.B.1    Schnittger, S.2    Jovanovic, J.V.3    Ommen, I.B.4    Hasle, H.5    Stergaard, M.6    Grimwade, D.7    Hokland, P.8
  • 204
    • 58549114892 scopus 로고    scopus 로고
    • The role of multiparameter flow cytometry for detection of minimal residual disease in acute myeloid leukemia
    • Al-Mawali A., Gillis D., Lewis I., The role of multiparameter flow cytometry for detection of minimal residual disease in acute myeloid leukemia American Journal of Clinical Pathology 2009 131 1 16 26
    • (2009) American Journal of Clinical Pathology , vol.131 , Issue.1 , pp. 16-26
    • Al-Mawali, A.1    Gillis, D.2    Lewis, I.3
  • 206
    • 0043025620 scopus 로고    scopus 로고
    • Comparison between conventional banding analysis and FISH screening with an AML-specific set of probes in 260 patients
    • DOI 10.1038/sj.thj.6200262
    • Cox M. C., Panetta P., Venditti A., Del Poeta G., Franchi A., Buccisano F., Tamburini A., Maurillo L., Amadori S., Comparison between conventional banding analysis and FISH screening with an AML-specific set of probes in 260 patients Hematology Journal 2003 4 4 263 270 (Pubitemid 36987222)
    • (2003) Hematology Journal , vol.4 , Issue.4 , pp. 263-270
    • Cox, M.C.1    Panetta, P.2    Venditti, A.3    Del Poeta, G.4    Franchi, A.5    Buccisano, F.6    Tamburini, A.7    Maurillo, L.8    Amadori, S.9
  • 207
    • 32544450834 scopus 로고    scopus 로고
    • Evaluation of complete disease remission in acute myeloid leukemia: A prospective study based on cytomorphology, interphase fluorescence in situ hybridization, and immunophenotyping during follow-up in patients with acute myeloid leukemia
    • DOI 10.1002/cncr.21665
    • Bacher U., Kern W., Schoch C., Schnittger S., Hiddemann W., Haferlach T., Evaluation of complete disease remission in acute myeloid leukemia: a prospective study based on cytomorphology, interphase fluorescence in situ hybridization, and immunophenotyping during follow-up in patients with acute myeloid leukemia Cancer 2006 106 4 839 847 (Pubitemid 43238451)
    • (2006) Cancer , vol.106 , Issue.4 , pp. 839-847
    • Bacher, U.1    Kern, W.2    Schoch, C.3    Schnittger, S.4    Hiddemann, W.5    Haferlach, T.6
  • 208
    • 34147121394 scopus 로고    scopus 로고
    • Utility of interphase FISH to stratify patients into cytogenetic risk categories at diagnosis of AML in an Eastern Cooperative Oncology Group (ECOG) clinical trial (E1900)
    • DOI 10.1016/j.leukres.2006.07.026, PII S0145212606002803
    • Vance G. H., Kim H., Hicks G. A., Cherry A. M., Higgins R., Hulshizer R. L., Tallman M. S., Fernandez H. F., Dewald G. W., Utility of interphase FISH to stratify patients into cytogenetic risk categories at diagnosis of AML in an Eastern Cooperative Oncology Group (ECOG) clinical trial (E1900) Leukemia Research 2007 31 5 605 609 (Pubitemid 46559998)
    • (2007) Leukemia Research , vol.31 , Issue.5 , pp. 605-609
    • Vance, G.H.1    Kim, H.2    Hicks, G.A.3    Cherry, A.M.4    Higgins, R.5    Hulshizer, R.L.6    Tallman, M.S.7    Fernandez, H.F.8    Dewald, G.W.9


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