Population-based demographic study of karyotypes in 1709 patients with adult acute myeloid leukemia

Leukemia

Volumn 20, Issue 3, 2006, Pages 444-450

  Sanderson, R N ^a   Johnson, P R E ^b   Moorman, A V ^c,f   Roman, E ^c,g   Willett, E ^c,g   Taylor, P R ^d   Proctor, S J ^d   Bown, N ^e   Ogston, S ^a   Bowen, D T ^a,h  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d ROYAL VICTORIA INFIRMARY   (United Kingdom)

^e NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^f Leeds General Hospital   (United Kingdom)

^g UNIVERSITY OF YORK   (United Kingdom)

^h LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Acute myeloid leukemia; Cytogenetics; Population based

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AGING; ANALYSIS OF VARIANCE; ARTICLE; CANCER REGISTRY; CHROMOSOME 12; CHROMOSOME 17; CHROMOSOME 18; CHROMOSOME 3; CHROMOSOME 5; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CHROMOSOME DELETION 5; CHROMOSOME DELETION 7; CHROMOSOME TRANSLOCATION 15; CHROMOSOME TRANSLOCATION 17; CHROMOSOME TRANSLOCATION 21; CHROMOSOME TRANSLOCATION 8; CYTOGENETICS; FEMALE; GENE FREQUENCY; HUMAN; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; PROGNOSIS; SEX RATIO; TRISOMY 8; UNITED KINGDOM;

EID: 33644558388     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404055     Document Type: Article

References (28)

1. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. Br J Haematol 1976; 33: 451-458.
2. Bennett JM. World Health Organization classification of the acute leukemias and myelodysplastic syndrome. Int J Hematol 2000; 72: 131-133.
3. Rowley JD, Golomb HM. The 4th International Workshop on chromosomes in leukemia - a prospective study of acute nonlymphocytic leukemia, Chicago, Illinois, USA, September 2-7 1982. Cancer Genetics And Cytogenetics 1984; 11: 249.
4. Bloomfield CD, Shuma C, Regal L, Philip PP, Hossfeld DK, Hagemeijer AM et al. Long-term survival of patients with acute myeloid leukemia: A third follow-up of the Fourth International Workshop on Chromosomes in Leukemia. Cancer 1997; 80 (11 Suppl): 2191-2198.
5. Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 1998; 92: 2322-2333.
6. Wheatley K, Burnett AK, Goldstone AH, Gray RG, Hann IM, Harrison CJ et al. A simple, robust, validated and highly predictive index for the determination of risk-directed therapy in acute myeloid leukaemia derived from the MRC AML 10 trial. United Kingdom Medical Research Council's Adult and Childhood Leukaemia Working Parties. Br J Haematol 1999; 107: 69-79.
7. Taylor PR, Reid MM, Stark AN, Bown N, Hamilton PJ, Proctor SJ. De novo acute myeloid leukaemia in patients over 55-years-old: A population-based study of incidence, treatment and outcome. Northern Region Haematology Group. Leukemia 1995; 9: 231-237.
8. Proctor SJ, Taylor PR. Age cohort subgroups in adult acute myeloid leukaemia studies - the population perspective. Leukemia 2001; 15: 188-189.
9. Preiss BS, Kerndrup GB, Schmidt KG, Sorensen AG, Clausen NA, Gadeberg OV et al. Cytogenetic findings in adult de novo acute myeloid leukaemia. A population-based study of 303/337 patients. Br J Haematol 2003; 123: 219-234.
10. Mitelman F. ISCN: An international system for human cytogenetic nomenclature. Basel, Switzerland: Karger, 1995.
11. Moorman AV, Roman E, Willett EV, Dovey GJ, Cartwright RA, Morgan GJ et al. Karyotype and age in acute myeloid leukemia Are they linked? Cancer Genet Cytogenet 2001; 126: 155-161.
12. Schoch C, Kern W, Krawitz P, Dugas M, Schnittger S, Haferlach T et al. Dependence of age-specific incidence of acute myeloid leukemia on karyotype. Blood 2001; 98: 3500.
13. Mauritzson N, Johansson B, Albin M, Billstrom R, Ahlgren T, Mikoczy Z et al. A single-center population-based consecutive series of 1500 cytogenetically investigated adult hematological malignancies: karyotypic features in relation to morphology, age and gender. Eur J Haematol 1999; 62: 95-102.
14. Moorman AV, Roman E, Cartwright RA, Morgan GJ. Patients entered into MRC AML trials are biologically representative of the totality of the disease in the UK. Clin Lab Haematol 2002; 24: 263-265.
15. Moorman AV, Roman E, Cartwright RA, Morgan GJ. Age-specific incidence rates for cytogenetically-defined subtypes of acute myeloid leukaemia. Br J Cancer 2002; 86: 1061-1063.
16. Vickers M, Jackson G, Taylor P. The incidence of acute promyelocytic leukemia appears constant over most of a human lifespan, implying only one rate limiting mutation. Leukemia 2000; 14: 722-726.
17. Mertens F, Johansson B, Mitelman F. Age- and gender-related heterogeneity of cancer chromosome aberrations. Cancer Genet Cytogenet 1993; 70: 6-11.
18. Cartwright RA, Gurney KA, Moorman AV. Sex ratios and the risks of haematological malignancies. Br J Haematol 2002; 118: 1071-1077.
19. Grimwade D, Walker H, Harrison G, Oliver F, Chatters S, Harrison CJ et al. The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): Analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial. Blood 2001; 98: 1312-1320.
20. Schoch C, Haferlach T, Bursch S, Gerstner D, Schnittger S, Dugas M et al. Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: A detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH. Genes Chromosomes Cancer 2002; 35: 20-29.
21. Pedersen-Bjergaard J, Andersen MK, Christiansen DH, Nerlov C. Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia. Blood 2002; 99: 1909-1912.
22. Castro PD, Liang JC, Nagarajan L. Deletions of chromosome 5q133 and 17p loci cooperate in myeloid neoplasms. Blood 2000; 95: 2138-2143.
23. Van Limbergen H, Poppe B, Michaux L, Herens C, Brown J, Noens L et al. Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH. Genes Chromosomes Cancer 2002; 33: 60-72.
24. Crescenzi B, Lastarza R, Romoli S, Beacci D, Matteucci C, Barba G et al. Submicroscopic deletions in 5q- associated malignancies. Haematologica 2004; 89: 281-285.
25. Paulsson K, Sall T, Fioretos T, Mitelman F, Johansson B. The incidence of trisomy 8 as a sole chromosomal aberration in myeloid malignancies varies in relation to gender, age, prior iatrogenic genotoxic exposure, and morphology. Cancer Genet Cytogenet 2001; 130: 160-165.
26. Wolman SR, Gundacker H, Appelbaum FR, Slovak ML. Impact of trisomy 8 (+8) on clinical presentation, treatment response, and survival in acute myeloid leukemia: A Southwest Oncology Group study. Blood 2002; 100: 29-35.
27. Schoch C, Haase D, Fonatsch C, Haferlach T, Loffler H, Schlegelberger B et al. The significance of trisomy 8 in de novo acute myeloid leukaemia: the accompanying chromosome aberrations determine the prognosis. German AML Cooperative Study Group. Br J Haematol 1997; 99: 605-611.
28. Nilsson L, Astrand-Grundstrom I, Anderson K, Arvidsson I, Hokland P, Bryder D et al. Involvement and functional impairment of the CD34+CD38-1+ hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8. Blood 2002; 100: 259-267.