메뉴 건너뛰기




Volumn 8, Issue 4, 2011, Pages 330-345

Oral lipid based drug delivery system (LBDDS): Formulation, characterization and application: A review

Author keywords

Bioavailability; Co surfactant; Oral absorption; Self micro nanoemulsifying drug delivery system (SMEDDS SNEDDS); Solubility; Surfactant

Indexed keywords

ACYLGLYCEROL; AVODAT; BEXAROTENE; CLOFAZIMINE; COSURFACTANT; CYCLOSPORIN; CYCLOSPORIN A; DRONABINOL; DRUG CARRIER; FORTAVASE; GELATIN; HALOFANTRINE; HECTROL; ISOTRETINOIN; LIPID; NANOSTRUCTURED LIPID CARRIER; NEROL; OIL; PHOSPHATIDYLCHOLINE; PLANT EXTRACT; PROGESTERONE; PUERARIA LOBATA EXTRACT; PUERARIN; RETINOIC ACID; RITONAVIR; ROCATROL; SILIBININ; SOLID LIPID NANOPARTICLE; SOLVENT; SURFACTANT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; WATER;

EID: 79959350104     PISSN: 15672018     EISSN: 18755704     Source Type: Journal    
DOI: 10.2174/156720111795767906     Document Type: Review
Times cited : (85)

References (134)
  • 1
    • 0000965958 scopus 로고
    • Transparent water-in-oil dispersions: The oleopathic hydro-micelle
    • Hoar, T.P.; Schulman, J.H. Transparent water-in-oil dispersions: the oleopathic hydro-micelle. Nature., 1943, 152, 102-103.
    • (1943) Nature , vol.152 , pp. 102-103
    • Hoar, T.P.1    Schulman, J.H.2
  • 2
    • 0001009759 scopus 로고
    • Mechanism of formation and structure of microemulsions by electron microscopy
    • Schulman, J.H.; Stoeckenius, W.; Prince, L.M. Mechanism of formation and structure of microemulsions by electron microscopy. J. Phys. Chem., 1959, 63, 1677-1680.
    • (1959) J. Phys. Chem , vol.63 , pp. 1677-1680
    • Schulman, J.H.1    Stoeckenius, W.2    Prince, L.M.3
  • 4
    • 1242271295 scopus 로고    scopus 로고
    • New microemulsion vehicle facilitates percutaneous penetration in vitro and cutaneous drug bioavailabil-ity in-vivo
    • Sintov, A.C.; Shapiro, L. New microemulsion vehicle facilitates percutaneous penetration in vitro and cutaneous drug bioavailabil-ity in-vivo. J. Control. Release., 2004, 95, 173-183.
    • (2004) J. Control. Release , vol.95 , pp. 173-183
    • Sintov, A.C.1    Shapiro, L.2
  • 6
    • 0023312532 scopus 로고
    • Organized surfactant systems: Microe-mulsions
    • Shinoda, K.; Lindman, B. Organized surfactant systems: microe-mulsions. Langmuir., 1987, 3, 135-149.
    • (1987) Langmuir , vol.3 , pp. 135-149
    • Shinoda, K.1    Lindman, B.2
  • 8
    • 0019461547 scopus 로고
    • Fat digestion in the newborn: Characterization of lipase in gastric aspirates of premature and term infants
    • Hamosh, M.; Scanon, J.W.; Ganot, D.; Like, M.; Scanlon, K.B.; Hamosh, P. Fat digestion in the newborn: characterization of lipase in gastric aspirates of premature and term infants. J. Clin. Invest., 1981, 67, 838-846.
    • (1981) J. Clin. Invest , vol.67 , pp. 838-846
    • Hamosh, M.1    Scanon, J.W.2    Ganot, D.3    Like, M.4    Scanlon, K.B.5    Hamosh, P.6
  • 9
    • 0021349430 scopus 로고
    • Dissolution rates of corticoid solutions dispersed on silicas
    • Liao, C.; Jarowski, C.I. Dissolution rates of corticoid solutions dispersed on silicas. J. Pharm. Sci., 1984, 73, 401-403.
    • (1984) J. Pharm. Sci , vol.73 , pp. 401-403
    • Liao, C.1    Jarowski, C.I.2
  • 10
    • 0024548560 scopus 로고
    • Fatty acids generated by gastric lipase promote human milk triacylglycerol digestion by pancreatic colipase-dependent lipase
    • Bemback, S.; Blackberg, L.; Hemell, O. Fatty acids generated by gastric lipase promote human milk triacylglycerol digestion by pancreatic colipase-dependent lipase. Biochim. Biophys. Acta., 1989, 101, 286-293.
    • (1989) Biochim. Biophys. Acta , vol.101 , pp. 286-293
    • Bemback, S.1    Blackberg, L.2    Hemell, O.3
  • 11
    • 0018886158 scopus 로고
    • Importance of phosphohpids, pancreatic phospholi- pase A, and fatty acid for the digestion of dietary fat
    • Borgstrom, B. Importance of phosphohpids, pancreatic phospholi- pase A, and fatty acid for the digestion of dietary fat. Gastroen- terology., 1980, 78, 954-962.
    • (1980) Gastroen- Terology , vol.78 , pp. 954-962
    • Borgstrom, B.1
  • 13
    • 0026586447 scopus 로고
    • Self-emulsifying drug delivery systems: Formulation and biopharmaceutic evaluation of an investigational lipophilic compound
    • Charman, S.A.; Charman, W.N.; Rogge, M.C; Wilson, T.D.; Dukto, F.J.; Pouton, C.W. Self-emulsifying drug delivery systems: Formulation and biopharmaceutic evaluation of an investigational lipophilic compound. Pharm. Res., 1992, 9, 87-93.
    • (1992) Pharm. Res , vol.9 , pp. 87-93
    • Charman, S.A.1    Charman, W.N.2    Rogge, M.C.3    Wilson, T.D.4    Dukto, F.J.5    Pouton, C.W.6
  • 14
    • 0033805858 scopus 로고    scopus 로고
    • Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and self-microemulsifying drug delivery systems
    • Pouton, C.W. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and self-microemulsifying drug delivery systems. Eur. J. Pharm. Sci., 2000, 11(2), S93-S98.
    • (2000) Eur. J. Pharm. Sci , vol.11 , Issue.2 , pp. 93-98
    • Pouton, C.W.1
  • 15
    • 0025565050 scopus 로고
    • Spontaneous formation of a water-continuous emulsion from water-in-oil microemulsion
    • Greiner, R.W.; Evans, D.F. Spontaneous formation of a water-continuous emulsion from water-in-oil microemulsion. Langmuir., 1990, 6, 1793-1796.
    • (1990) Langmuir , vol.6 , pp. 1793-1796
    • Greiner, R.W.1    Evans, D.F.2
  • 16
    • 0028194817 scopus 로고
    • Self-emulsifying drug delivery systems (SEDDS) with poly-glycolyzed glycerides for improving in-vitro dissolution and oral absorption of lipophilic drugs
    • Shah, N.H.; Caravajal, M.T.; Patel, C.L.; Infeld, M.H.; Malick, A.W. Self-emulsifying drug delivery systems (SEDDS) with poly-glycolyzed glycerides for improving in-vitro dissolution and oral absorption of lipophilic drugs. Int. J. Pharm., 1994, 106, 15-23.
    • (1994) Int. J. Pharm , vol.106 , pp. 15-23
    • Shah, N.H.1    Caravajal, M.T.2    Patel, C.L.3    Infeld, M.H.4    Malick, A.W.5
  • 17
    • 0027301116 scopus 로고
    • An investigation into the physicochemical properties of self-emulsifying systems using low frequency dielectric spectroscopy, surface tension measurements and particle size analysis
    • Craig, D.Q.M.; Lievens, H.S.R.; Pitt, K.G.; Storey, D.E. An investigation into the physicochemical properties of self-emulsifying systems using low frequency dielectric spectroscopy, surface tension measurements and particle size analysis. Int. J. Pharm., 1993, 96, 147-155.
    • (1993) Int. J. Pharm , vol.96 , pp. 147-155
    • Craig, D.Q.M.1    Lievens, H.S.R.2    Pitt, K.G.3    Storey, D.E.4
  • 18
    • 38949117575 scopus 로고    scopus 로고
    • Approaches for the development of solid and semi-solid lipid-based formulations
    • Jannin, V.; Musakhanian, J.; Marchaud, D. Approaches for the development of solid and semi-solid lipid-based formulations. Adv Drug Deliv Rev., 2008, 60, 734-746.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 734-746
    • Jannin, V.1    Musakhanian, J.2    Marchaud, D.3
  • 20
    • 0034948974 scopus 로고    scopus 로고
    • Once-a-day oral dosing regimen of Cyclosporin A: Combined therapy of Cyclosporin A premicroemulsion concentrates and enteric coated solid-state pre-microemulsion concentrates
    • Kim, C.; Shin, H.; Yang, S.; Kim, J.; Oh, Y. Once-a-day oral dosing regimen of Cyclosporin A: Combined therapy of Cyclosporin A premicroemulsion concentrates and enteric coated solid-state pre-microemulsion concentrates. Pharm. Res., 2001, 18, 454-459.
    • (2001) Pharm. Res , vol.18 , pp. 454-459
    • Kim, C.1    Shin, H.2    Yang, S.3    Kim, J.4    Oh, Y.5
  • 21
    • 0032830863 scopus 로고    scopus 로고
    • Reduction of tablet coloration at tableting for oily medicine (to-copheryl nicotinate)
    • Takashima, Y.; Yuasa, H.; Kanaya, Y.; Nomura, I.; Shinozawa, K. Reduction of tablet coloration at tableting for oily medicine (to-copheryl nicotinate). Int. J. Pharm., 1999, 187, 125-135.
    • (1999) Int. J. Pharm , vol.187 , pp. 125-135
    • Takashima, Y.1    Yuasa, H.2    Kanaya, Y.3    Nomura, I.4    Shinozawa, K.5
  • 22
    • 0033135447 scopus 로고    scopus 로고
    • Gas-assisted IR-ATR probe for detection of volatile compounds in aqueous solutions
    • Yang, J.; Her, J.W. Gas-assisted IR-ATR probe for detection of volatile compounds in aqueous solutions. Anal. Chem., 1999, 71, 1773-1779.
    • (1999) Anal. Chem , vol.71 , pp. 1773-1779
    • Yang, J.1    Her, J.W.2
  • 23
    • 0026793126 scopus 로고
    • Powdered solution technology: Principles and mechanism
    • Spireas, S.S.; Jarowski, C.L.; Rohera, B.D. Powdered solution technology: principles and mechanism. Pharm. Res., 1992, 9, 1351-1358.
    • (1992) Pharm. Res , vol.9 , pp. 1351-1358
    • Spireas, S.S.1    Jarowski, C.L.2    Rohera, B.D.3
  • 24
    • 0032109669 scopus 로고    scopus 로고
    • In vitro release evaluation of hy-drocortisone liquisolid tablets
    • Spireas, S.; Sadu, S.; Grover, R. In vitro release evaluation of hy-drocortisone liquisolid tablets. J. Pharm. Sci., 1998, 87, 867-872.
    • (1998) J. Pharm. Sci , vol.87 , pp. 867-872
    • Spireas, S.1    Sadu, S.2    Grover, R.3
  • 26
    • 0025317916 scopus 로고
    • Use of powdered solutions to improve the dissolution rate of polythiazide tablets
    • Sheth, A.; Jarowski, C.I. Use of powdered solutions to improve the dissolution rate of polythiazide tablets. Drug Dev. Ind. Pharm., 1990, 16, 769-777.
    • (1990) Drug Dev. Ind. Pharm , vol.16 , pp. 769-777
    • Sheth, A.1    Jarowski, C.I.2
  • 28
    • 0020461661 scopus 로고
    • Studies on direct compression of tablets. Part 4. Effect of particle size on the mechanical strength of tablets
    • Alderborn, G.; Nystrom, C. Studies on direct compression of tablets. Part 4. Effect of particle size on the mechanical strength of tablets. Acta. Pharm. Suec., 1982, 19, 381-390.
    • (1982) Acta. Pharm. Suec , vol.19 , pp. 381-390
    • Alderborn, G.1    Nystrom, C.2
  • 29
    • 0020389709 scopus 로고
    • Studies on direct compression of tablets. Part 6. Evaluation of methods for the estimation of particle fragmentation during compaction
    • Duberg, M.; Nystrom, C. Studies on direct compression of tablets. Part 6. Evaluation of methods for the estimation of particle fragmentation during compaction. Acta. Pharm. Suec., 1982, 19, 421-436.
    • (1982) Acta. Pharm. Suec , vol.19 , pp. 421-436
    • Duberg, M.1    Nystrom, C.2
  • 30
    • 0035857733 scopus 로고    scopus 로고
    • Effect of initial particle size on the tableting properties of L-lysine monohydrochloride dihydrate powder
    • Sun, C.; Grant, D.J.W. Effect of initial particle size on the tableting properties of L-lysine monohydrochloride dihydrate powder. Int. J. Pharm., 2001a, 215, 221-228.
    • (2001) Int. J. Pharm , vol.215 , pp. 221-228
    • Sun, C.1    Grant, D.J.W.2
  • 31
    • 0035013530 scopus 로고    scopus 로고
    • Influence of elastic deformation of particles on Heckel analysis
    • Sun, C.; Grant, D.J.W. Influence of elastic deformation of particles on Heckel analysis. Pharm. Dev. Tech., 2001b, 6, 193-200.
    • (2001) Pharm. Dev. Tech , vol.6 , pp. 193-200
    • Sun, C.1    Grant, D.J.W.2
  • 32
    • 0034949446 scopus 로고    scopus 로고
    • Compaction properties of L-lysine salts
    • Sun, C.; Grant, D.J.W. Compaction properties of L-lysine salts. Pharm. Res., 2001c, 18, 281-286.
    • (2001) Pharm. Res , vol.18 , pp. 281-286
    • Sun, C.1    Grant, D.J.W.2
  • 33
    • 0021950969 scopus 로고
    • Force displacement measurements in tableting
    • Ragnarsson, G.; Sjogren, J. Force displacement measurements in tableting. J. Pharm. Pharmacol., 1985, 37, 145-150.
    • (1985) J. Pharm. Pharmacol , vol.37 , pp. 145-150
    • Ragnarsson, G.1    Sjogren, J.2
  • 34
    • 0025243505 scopus 로고
    • Evaluation of a per-meametry technique for surface area measurements of coarse par-ticulate materials
    • Eriksson, M.; Nystrom, C.; Alderborn, G. Evaluation of a per-meametry technique for surface area measurements of coarse par-ticulate materials. Int. J. Pharm., 1990, 63, 189-199.
    • (1990) Int. J. Pharm , vol.63 , pp. 189-199
    • Eriksson, M.1    Nystrom, C.2    Alderborn, G.3
  • 35
    • 0000693333 scopus 로고
    • An analysis of powder compaction phenomena
    • Heckel, R.W. An analysis of powder compaction phenomena. Trans. Metall. Soc. AIME., 1961a, 221, 1001-1008.
    • (1961) Trans. Metall. Soc. AIME , vol.221 , pp. 1001-1008
    • Heckel, R.W.1
  • 36
    • 0000292691 scopus 로고
    • Density-pressure relationship in powder compaction
    • Heckel, R.W. Density-pressure relationship in powder compaction. Trans. Metall. Soc. AIME., 1961b, 221, 671-675.
    • (1961) Trans. Metall. Soc. AIME , vol.221 , pp. 671-675
    • Heckel, R.W.1
  • 37
    • 3042586026 scopus 로고    scopus 로고
    • Physical chemical considerations of lipid-based oral drug delivery- solid lipid nanoparticles
    • Bummer, P.M. Physical chemical considerations of lipid-based oral drug delivery- solid lipid nanoparticles. Crit. Rev. Ther. Drug carr. Syst., 2004, 21, 1-19.
    • (2004) Crit. Rev. Ther. Drug Carr. Syst , vol.21 , pp. 1-19
    • Bummer, P.M.1
  • 38
    • 0029562489 scopus 로고
    • Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects
    • Constantinides, P.P. Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects. Pharm. Res., 1995, 12, 1561-1572.
    • (1995) Pharm. Res , vol.12 , pp. 1561-1572
    • Constantinides, P.P.1
  • 39
    • 0034614208 scopus 로고    scopus 로고
    • Microemulsion based media as a novel drug delivery system
    • Lawrence, M.J.; Rees, G.D. Microemulsion based media as a novel drug delivery system. Adv. drug delivery. Rev., 2002, 45, 89-121.
    • (2002) Adv. Drug Delivery. Rev , vol.45 , pp. 89-121
    • Lawrence, M.J.1    Rees, G.D.2
  • 40
    • 0002656064 scopus 로고
    • Self-emulsification of vegetable oil -nonionic surfactant mixture: A proposed mechanism of action
    • Wakerly, M.G.; Pouton, C.W.; Meakin, B.J.; Morton, F.S. Self-emulsification of vegetable oil -nonionic surfactant mixture: a proposed mechanism of action. ACS Symp. Ser., 1986. 311, 242-255.
    • (1986) ACS Symp. Ser , vol.311 , pp. 242-255
    • Wakerly, M.G.1    Pouton, C.W.2    Meakin, B.J.3    Morton, F.S.4
  • 41
    • 0028949717 scopus 로고
    • An investigation into the mechanism of self-emulsification using particle size analysis and low frequency dielectric spectroscopy
    • Craig, D.Q.M.; Barker, S.A.; Banning, D.; Booth, S.W. An investigation into the mechanism of self-emulsification using particle size analysis and low frequency dielectric spectroscopy. Int. J. Pharm., 1995, 114, 103-110.
    • (1995) Int. J. Pharm , vol.114 , pp. 103-110
    • Craig, D.Q.M.1    Barker, S.A.2    Banning, D.3    Booth, S.W.4
  • 42
    • 0001985343 scopus 로고
    • Microemulsions
    • J. Kreuter., Ed.; Marcel Dekker.; New York
    • Attwood, D. Microemulsions. In Colloidal drug Delivery Systems. J. Kreuter., Ed.; Marcel Dekker.; New York, 1994, pp. 31-71.
    • (1994) Colloidal Drug Delivery Systems , pp. 31-71
    • Attwood, D.1
  • 43
    • 0002213717 scopus 로고
    • Using microemulsions for drug delivery
    • Bhargava, H.N.; Namrkar, A.; Lieb, L.M. Using microemulsions for drug delivery. Pharm. Tech., 1987, 11, 46-52.
    • (1987) Pharm. Tech , vol.11 , pp. 46-52
    • Bhargava, H.N.1    Namrkar, A.2    Lieb, L.M.3
  • 44
    • 0000009718 scopus 로고
    • Microemulsions
    • J. Swarbrick and J.C. Boylan, Ed.; Marcel Dekker, New York
    • Eccleston, J. Microemulsions. In Encyclopedia of Pharmaceutical Technology Vol. 9. J. Swarbrick and J.C. Boylan, Ed.; Marcel Dekker, New York., 1994, pp. 375-421.
    • (1994) In Encyclopedia of Pharmaceutical Technology , vol.9 , pp. 375-421
    • Eccleston, J.1
  • 45
    • 0028130738 scopus 로고
    • Surfactant systems: Microemulsions and vesicles as vehicles for drug delivery
    • Lawrence, M.J. Surfactant systems: microemulsions and vesicles as vehicles for drug delivery. Eur. J. Drug Metab. Pharmacokinet., 1994, 3, 257-269.
    • (1994) Eur. J. Drug Metab. Pharmacokinet , vol.3 , pp. 257-269
    • Lawrence, M.J.1
  • 46
  • 47
    • 0033430984 scopus 로고    scopus 로고
    • Microemulsions: An overview and pharmaceutical applications
    • Tenjarla, S. Microemulsions: an overview and pharmaceutical applications. Crit. Rev. Ther. Drug Carrier Systems., 1999, 16, 461-521.
    • (1999) Crit. Rev. Ther. Drug Carrier Systems , vol.16 , pp. 461-521
    • Tenjarla, S.1
  • 49
    • 0018925391 scopus 로고
    • Microemulsion systems with a non-ionic co-surfactant
    • Sagitani, H.; Friberg, S. Microemulsion systems with a non-ionic co-surfactant. J. Disper. Sci. Technol., 1980, 1, 151-164.
    • (1980) J. Disper. Sci. Technol , vol.1 , pp. 151-164
    • Sagitani, H.1    Friberg, S.2
  • 50
    • 0026757902 scopus 로고
    • Phase studies of oil-in-water phospholipid microemulsions
    • Attwood, D.; Mallon, C.; Taylor, C.J. Phase studies of oil-in-water phospholipid microemulsions. Int. J. Pharm., 1992, 84, R5-R8.
    • (1992) Int. J. Pharm , vol.84 , pp. 5-8
    • Attwood, D.1    Mallon, C.2    Taylor, C.J.3
  • 51
    • 0028145622 scopus 로고
    • Investigations into the formation and characterization of phosphol-ipid microemulsions. III. Pseudo-ternary phase diagrams of systems containing water-lecithin-isopropyl myristate and either an al-kanoic acid, amine, alkanediol, polyethylene glycol alkyl ether or alcohol as co-surfactant
    • Aboofazeli, R.; Lawrence, C.B.; Wicks, S.R.; Lawrence, M.J. Investigations into the formation and characterization of phosphol-ipid microemulsions. III. Pseudo-ternary phase diagrams of systems containing water-lecithin-isopropyl myristate and either an al-kanoic acid, amine, alkanediol, polyethylene glycol alkyl ether or alcohol as co-surfactant. Int. J. Pharm., 1994, 111, 63-72.
    • (1994) Int. J. Pharm , vol.111 , pp. 63-72
    • Aboofazeli, R.1    Lawrence, C.B.2    Wicks, S.R.3    Lawrence, M.J.4
  • 52
    • 33947126116 scopus 로고    scopus 로고
    • Light scattering investigations on dilute non-ionic oil-in-water microemulsions
    • Warisnoicharoen, W.; Lansley, A.B., Lawrence, M.J. Light scattering investigations on dilute non-ionic oil-in-water microemulsions. AAPS Pharm. Sci., 2000, 2, 429-448.
    • (2000) AAPS Pharm. Sci , vol.2 , pp. 429-448
    • Warisnoicharoen, W.1    Lansley, A.B.2    Lawrence, M.J.3
  • 54
    • 0001185268 scopus 로고    scopus 로고
    • Dynamics of water-containing sodium bis (2-ethylhexyl) sulfosuc-cinate (AOT) reverse micelles: A high-frequency dielectric study
    • D'Angelo, M.; Fioretto, D.; Onori, G.; Palmieri, L.; Santiicci, A. Dynamics of water-containing sodium bis (2-ethylhexyl) sulfosuc-cinate (AOT) reverse micelles: a high-frequency dielectric study. Phys. Rev., 1996, E54, 993-996.
    • (1996) Phys. Rev , vol.E54 , pp. 993-996
    • D'Angelo, M.1    Fioretto, D.2    Onori, G.3    Palmieri, L.4    Santiicci, A.5
  • 55
    • 0342360279 scopus 로고
    • Variation of surfactant counter ion and its effect on the structure and properties of Aerosol-OT-based water-in-oil mi-croemulsions
    • Eastoe, J.; Fragneto, G.; Robinson, B.H., Towey, T.F., Heenan, R.K., Lena, F.J. Variation of surfactant counter ion and its effect on the structure and properties of Aerosol-OT-based water-in-oil mi-croemulsions. J. Chem. Soc., 1992, 88, 461-467.
    • (1992) J. Chem. Soc , vol.88 , pp. 461-467
    • Eastoe, J.1    Fragneto, G.2    Robinson, B.H.3    Towey, T.F.4    Heenan, R.K.5    Lena, F.J.6
  • 56
    • 0001315945 scopus 로고
    • Effect of oil chain length and electrolytes on water solubilization in alcohol-free pharmaceutical micro-emulsions
    • Johnston, K.A.; Shah, D.O. Effect of oil chain length and electrolytes on water solubilization in alcohol-free pharmaceutical micro-emulsions. J. Colloid Interface Sci., 1985, 107, 269-271.
    • (1985) J. Colloid Interface Sci , vol.107 , pp. 269-271
    • Johnston, K.A.1    Shah, D.O.2
  • 57
    • 0021385127 scopus 로고
    • Structures and stability of isotropic phases in the AOT decane- water system
    • Larche, F.C.; Delord, P. Structures and stability of isotropic phases in the AOT decane- water system. Fluid Phase Equilib., 1985, 20, 257-64.
    • (1985) Fluid Phase Equilib , vol.20 , pp. 257-264
    • Larche, F.C.1    Delord, P.2
  • 58
    • 0001505803 scopus 로고
    • Solubilization of drugs in microemulsions as studied by dielectric spectroscopy
    • Skodvin, T.; Sjoblem, J.; Saeten, J.O.; Gestblom, B. Solubilization of drugs in microemulsions as studied by dielectric spectroscopy. J. Colloid Interface Sci., 1993, 155, 392-401.
    • (1993) J. Colloid Interface Sci , vol.155 , pp. 392-401
    • Skodvin, T.1    Sjoblem, J.2    Saeten, J.O.3    Gestblom, B.4
  • 59
    • 0027241705 scopus 로고
    • Investigations into the formation and characterization of phospholipid microemulsions: I Pseudo-ternary phase diagrams of systems containing water-lecithin-alcohol-isopropyl myristate
    • Aboofazeli, R.; Lawrence, M.J. Investigations into the formation and characterization of phospholipid microemulsions: I Pseudo-ternary phase diagrams of systems containing water-lecithin-alcohol-isopropyl myristate. Int. J. Pharm., 1993, 93, 161-175.
    • (1993) Int. J. Pharm , vol.93 , pp. 161-175
    • Aboofazeli, R.1    Lawrence, M.J.2
  • 60
    • 0002280821 scopus 로고
    • Structure and phase behavior of lecithin-based microemulsions: A study of chain length dependence
    • Schurtenberger, P.; Peng, Q.; Leser, M.; Luisi, P.L. Structure and phase behavior of lecithin-based microemulsions: a study of chain length dependence. J. Colloid Interface Sci., 1993, 156, 43-51.
    • (1993) J. Colloid Interface Sci , vol.156 , pp. 43-51
    • Schurtenberger, P.1    Peng, Q.2    Leser, M.3    Luisi, P.L.4
  • 61
    • 0031980405 scopus 로고    scopus 로고
    • A study on the in vitro percutaneous absorption of propranolol from disperse system
    • Kitistis, G.; Niopas, I. A study on the in vitro percutaneous absorption of propranolol from disperse system. J. Pharm. Pharmacol., 1998, 50, 413-419.
    • (1998) J. Pharm. Pharmacol , vol.50 , pp. 413-419
    • Kitistis, G.1    Niopas, I.2
  • 62
    • 0024574278 scopus 로고
    • Solubiliza-tion of indomethacin by polysorbate 80 in mixed water-sorbitol solvents
    • Attwood, D.; Ktistis, G.; McCormick, Y.; Story, M.J. Solubiliza-tion of indomethacin by polysorbate 80 in mixed water-sorbitol solvents. J Pharm. Pharmacol., 1989, 41, 83-6.
    • (1989) J Pharm. Pharmacol , vol.41 , pp. 83-86
    • Attwood, D.1    Ktistis, G.2    McCormick, Y.3    Story, M.J.4
  • 63
    • 0011379669 scopus 로고
    • Entropy-induced dispersion of bulk liquids
    • Reiss, H. Entropy-induced dispersion of bulk liquids. J. Colloid Interface. Sci., 1975, 53, 61-70.
    • (1975) J. Colloid Interface. Sci , vol.53 , pp. 61-70
    • Reiss, H.1
  • 64
    • 0017097531 scopus 로고
    • The self-emulsifying action of mixed surfactants in oil
    • Groves, M.J.; Galindez, D.A.D. The self-emulsifying action of mixed surfactants in oil. Acta. Pharma. Suecica., 1976b, 13, 361-372.
    • (1976) Acta. Pharma. Suecica , vol.13 , pp. 361-372
    • Groves, M.J.1    Galindez, D.A.D.2
  • 65
    • 0016296842 scopus 로고
    • Measurement of the spontaneity of self emulsifiable oils
    • Groves, M.J., Mustafa, R.M.A. Measurement of the spontaneity of self emulsifiable oils. J. Pharm. Pharmcol., 1974, 26, 671-681.
    • (1974) J. Pharm. Pharmcol , vol.26 , pp. 671-681
    • Groves, M.J.1    Mustafa, R.M.A.2
  • 66
    • 0022366625 scopus 로고
    • Self-emulsifying drug delivery systems: Assessment of the efficiency of emulsification
    • Pouton, C.W. Self-emulsifying drug delivery systems: assessment of the efficiency of emulsification. Int. J. Pharm., 1985, 27, 335-348.
    • (1985) Int. J. Pharm , vol.27 , pp. 335-348
    • Pouton, C.W.1
  • 67
    • 57449109685 scopus 로고    scopus 로고
    • Design and optimization of a new self-nanoemulsifying drug delivery system
    • Lijuan, W.; Jinfeng, D.; Jing, C.; Julian, E.; Xuefeng, Li. Design and optimization of a new self-nanoemulsifying drug delivery system. J. Colloid Interface. Sci., 2009, 330, 443-448.
    • (2009) J. Colloid Interface. Sci , vol.330 , pp. 443-448
    • Lijuan, W.1    Jinfeng, D.2    Jing, C.3    Julian, E.4    Xuefeng, L.5
  • 68
    • 0029052680 scopus 로고
    • Pharmaceutical characterization of commercially available intravenous fat emulsions: Estimation of average particle size, size distribution and surface potential using photon correlation spectroscopy
    • Komatsu, H.; Kitajima, A.; Okada, S. Pharmaceutical characterization of commercially available intravenous fat emulsions: Estimation of average particle size, size distribution and surface potential using photon correlation spectroscopy. Chem. Pharm. Bull., 1995, 43, 1412-11415.
    • (1995) Chem. Pharm. Bull , vol.43 , pp. 1412-11415
    • Komatsu, H.1    Kitajima, A.2    Okada, S.3
  • 69
    • 0025630749 scopus 로고
    • The stability of intravenous fat emulsions in total parenteral nutrition mixtures
    • Washington, C. The stability of intravenous fat emulsions in total parenteral nutrition mixtures. Int. J. Pharm., 1990, 66, 1-21.
    • (1990) Int. J. Pharm , vol.66 , pp. 1-21
    • Washington, C.1
  • 70
    • 23144432623 scopus 로고    scopus 로고
    • Effect of formulation variables on preparation and evaluation of gelled self-emulsifying drug delivery system (SEDDS) of ketoprofen
    • Patil, P.; Joshij J.; Paradkar, P. Effect of formulation variables on preparation and evaluation of gelled self-emulsifying drug delivery system (SEDDS) of ketoprofen. AAPS Pharm. Sci Tech., 2004, 5, 34-42.
    • (2004) AAPS Pharm. Sci Tech , vol.5 , pp. 34-42
    • Patil, P.1    Joshij, J.2    Paradkar, P.3
  • 71
    • 33847665647 scopus 로고    scopus 로고
    • Formulation of self-emulsifying drug delivery system for oral delivery of simvastatin: In vitro and in vivo evaluation
    • Patil, P.; Vandana, P.; Paradkar, P. Formulation of self-emulsifying drug delivery system for oral delivery of simvastatin: In vitro and in vivo evaluation. Acta. pharma., 2007, 57, 111-122.
    • (2007) Acta. Pharma , vol.57 , pp. 111-122
    • Patil, P.1    Vandana, P.2    Paradkar, P.3
  • 72
    • 0017200358 scopus 로고
    • Rheological characterization of self-emulsifying oil/surfactant systems
    • Groves, M.J.; Galindez, D.A D. Rheological characterization of self-emulsifying oil/surfactant systems. Acta. Pharma. Suecica., 1976a, 13, 353-360.
    • (1976) Acta. Pharma. Suecica , vol.13 , pp. 353-360
    • Groves, M.J.1    Galindez, D.A.D.2
  • 73
    • 0032049097 scopus 로고    scopus 로고
    • Water diffusion and head group mobility in polymer-like reverse micelles: Evidence of a sphere-to-rod-to-sphere transition
    • Angelico, R.; Palazzo, G.; Colafemmina, G.; Cirkel, P.A., Giustini, M.; Ceglie, A. Water diffusion and head group mobility in polymer-like reverse micelles: evidence of a sphere-to-rod-to-sphere transition. J. Phys. Chem., 1998, 102, 2883-2889.
    • (1998) J. Phys. Chem , vol.102 , pp. 2883-2889
    • Angelico, R.1    Palazzo, G.2    Colafemmina, G.3    Cirkel, P.A.4    Giustini, M.5    Ceglie, A.6
  • 74
    • 0029289958 scopus 로고
    • Reversed micellar solution-to-bicontinuous microemulsion transition in sodium bis(2-ethylhexyl) phosphate/n-heptane/water system
    • Yu, Z.J.; Neuman, R.D. Reversed micellar solution-to-bicontinuous microemulsion transition in sodium bis(2-ethylhexyl) phosphate/n-heptane/water system. Langmuir., 1995, 11, 1081-1086.
    • (1995) Langmuir , vol.11 , pp. 1081-1086
    • Yu, Z.J.1    Neuman, R.D.2
  • 76
    • 0032783044 scopus 로고    scopus 로고
    • Gelatin-stabilized micro-emulsion-based organogels: Rheology and application in iontopho-retic transdermal drug delivery
    • Kantaria, S.; Rees, G.D.; Lawrence, M.J. Gelatin-stabilized micro-emulsion-based organogels: rheology and application in iontopho-retic transdermal drug delivery. J. Control. Rel., 1999, 60, 355-365.
    • (1999) J. Control. Rel , vol.60 , pp. 355-365
    • Kantaria, S.1    Rees, G.D.2    Lawrence, M.J.3
  • 77
    • 0030639471 scopus 로고    scopus 로고
    • Effect of oil phase composition on the skin permeation of felodipine from (o/w) microemulsions
    • Trotta, M.; Morel S.; Gasco, M.R. Effect of oil phase composition on the skin permeation of felodipine from (o/w) microemulsions. Phamiazie., 1997, 52, 50-53.
    • (1997) Phamiazie , vol.52 , pp. 50-53
    • Trotta, M.1    Morel, S.2    Gasco, M.R.3
  • 79
    • 0001157781 scopus 로고
    • Water/AOT/ethane microemulsion under supercritical conditions as a reaction medium
    • Kushima, Y.; Saito, N.; Hatakeda, K.; Arai, M. Water/AOT/ethane microemulsion under supercritical conditions as a reaction medium. J. Supercrit. Fluids., 1988, 13, 217-224.
    • (1988) J. Supercrit. Fluids , vol.13 , pp. 217-224
    • Kushima, Y.1    Saito, N.2    Hatakeda, K.3    Arai, M.4
  • 81
    • 0032085722 scopus 로고    scopus 로고
    • Branching and percolation in lecithin wormlike micelles studied by dielectric spec-troscopy
    • Cirkel, P.A.; van der Ploeg, J.P.M.; Koper, G.J.M. Branching and percolation in lecithin wormlike micelles studied by dielectric spec-troscopy. Phys. Rev., 1998, E57, 6875-6883.
    • (1998) Phys. Rev , vol.E57 , pp. 6875-6883
    • Cirkel, P.A.1    van der Ploeg, J.P.M.2    Koper, G.J.M.3
  • 83
    • 0023366035 scopus 로고
    • The characterization of heterogeneous gels by a dielectric technique: 1. Theory and preliminary evaluation
    • Dissado, L.A.; Rowe, R.C.; Hadar, A.; Hill, R.M. The characterization of heterogeneous gels by a dielectric technique: 1. Theory and preliminary evaluation. J. Colloid Interface Sci., 1987, 117, 310-324.
    • (1987) J. Colloid Interface Sci , vol.117 , pp. 310-324
    • Dissado, L.A.1    Rowe, R.C.2    Hadar, A.3    Hill, R.M.4
  • 84
    • 0023999199 scopus 로고
    • The characterization of heterogeneous gels by means of a dielectric technique: 2. Formulation and structural considerations
    • Rowe, R.C.; Dissado, L.A.; Zaidi, S.H.; Hill, R.M. The characterization of heterogeneous gels by means of a dielectric technique: 2. Formulation and structural considerations. J. Colloid Interface Sci., 1988, 122, 354-366.
    • (1988) J. Colloid Interface Sci , vol.122 , pp. 354-366
    • Rowe, R.C.1    Dissado, L.A.2    Zaidi, S.H.3    Hill, R.M.4
  • 86
    • 34247609989 scopus 로고    scopus 로고
    • Development and bioavailability assessment of ramipril nanoemulsion formulation
    • Shafiq, S.; Talegaonkar, S.; Ahmad, F.J.; Khar, R.K.; Ali, M. Development and bioavailability assessment of ramipril nanoemulsion formulation. Eur. J. Pharm. Biopharm., 2007; 66: 227-243.
    • (2007) Eur. J. Pharm. Biopharm , vol.66 , pp. 227-243
    • Shafiq, S.1    Talegaonkar, S.2    Ahmad, F.J.3    Khar, R.K.4    Ali, M.5
  • 90
    • 0023010568 scopus 로고
    • An experimental system designed to study the in situ intestinal lymphatic transport of lipo-philic drugs in anesthetized rats
    • Charman, W.N.; Noguchi, T.; Stella, V.J. An experimental system designed to study the in situ intestinal lymphatic transport of lipo-philic drugs in anesthetized rats. Int. J. Pharm., 1986, 33, 155-164.
    • (1986) Int. J. Pharm , vol.33 , pp. 155-164
    • Charman, W.N.1    Noguchi, T.2    Stella, V.J.3
  • 91
    • 0033818432 scopus 로고    scopus 로고
    • Effect of short-, medium-, and long-chain fatty acid based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats
    • Caliph, S.M.; Charman, W.N.; Porter, C.J.H. Effect of short-, medium-, and long-chain fatty acid based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats. J. Pharm. Sci., 2000, 89, 1073-1084.
    • (2000) J. Pharm. Sci , vol.89 , pp. 1073-1084
    • Caliph, S.M.1    Charman, W.N.2    Porter, C.J.H.3
  • 92
    • 0034854134 scopus 로고    scopus 로고
    • Comparison of the lymphatic transport of halofantrine administered in dispersed systems containing three different unsaturated fatty acids
    • Holm, R.; Mullertz, A.; Pedersen, G.P.; Kristensen, H.G. Comparison of the lymphatic transport of halofantrine administered in dispersed systems containing three different unsaturated fatty acids. Pharm. Res., 2001, 18, 1299-1304.
    • (2001) Pharm. Res , vol.18 , pp. 1299-1304
    • Holm, R.1    Mullertz, A.2    Pedersen, G.P.3    Kristensen, H.G.4
  • 93
    • 0030834788 scopus 로고    scopus 로고
    • Formulation and physical characterization of water-in-oil microemulsions containing long versus medium chain length glycerides
    • Constantinides, P.P.; Scalart, J.P. Formulation and physical characterization of water-in-oil microemulsions containing long versus medium chain length glycerides. Int. J. pharm., 1997, 158, 57-68.
    • (1997) Int. J. Pharm , vol.158 , pp. 57-68
    • Constantinides, P.P.1    Scalart, J.P.2
  • 94
    • 0029074505 scopus 로고
    • Using microemulsion formulations for drug delivery of therapeutic peptides
    • Sarciaux, J.M.; Acar, L.; Sado, P.A. Using microemulsion formulations for drug delivery of therapeutic peptides. Int. J. Pharm., 1995, 120, 127-136.
    • (1995) Int. J. Pharm , vol.120 , pp. 127-136
    • Sarciaux, J.M.1    Acar, L.2    Sado, P.A.3
  • 95
    • 0031000858 scopus 로고    scopus 로고
    • Sterilization and freeze-drying of drug-free and drug-loaded solid lipid nanoparticles
    • Cavalli, R.; Caputo, O.; Carlotti, M. E.; Trotta, M.; Scamecchia, S.; Gasco, M.R. Sterilization and freeze-drying of drug-free and drug-loaded solid lipid nanoparticles. Int. J. Pharm., 1997, 148, 47-54.
    • (1997) Int. J. Pharm , vol.148 , pp. 47-54
    • Cavalli, R.1    Caputo, O.2    Carlotti, M.E.3    Trotta, M.4    Scamecchia, S.5    Gasco, M.R.6
  • 97
    • 24444443072 scopus 로고
    • Incorporation in lipospheres of [D-Trp-61] LHRH
    • Morel, S.; Gasco, M.R., Cavalli, R. Incorporation in lipospheres of [D-Trp-61] LHRH. Int. J. Pharm., 1994, 105, R1-R3.
    • (1994) Int. J. Pharm , vol.105 , pp. 1-3
    • Morel, S.1    Gasco, M.R.2    Cavalli, R.3
  • 98
    • 0026007957 scopus 로고
    • Optimization of doxombi-cine incorporation and of the yield of polybutylcyanoacrylate nanoparticles
    • Carpignano, R.; Gasco, M.R.; Morel, S. Optimization of doxombi-cine incorporation and of the yield of polybutylcyanoacrylate nanoparticles. Pharm. Acta Helv., 1991, 66, 28-32.
    • (1991) Pharm. Acta Helv , vol.66 , pp. 28-32
    • Carpignano, R.1    Gasco, M.R.2    Morel, S.3
  • 99
    • 0026073486 scopus 로고
    • Doxombicine englobed in polybutylcyanoacrylate nanocapsules: Behavior in vitro and in vivo
    • Gasco, M.R.; Morel, S.; Trotta, M.; Viano, I. Doxombicine englobed in polybutylcyanoacrylate nanocapsules: behavior in vitro and in vivo. Pharm. Acta Helv., 1991, 66, 47-49.
    • (1991) Pharm. Acta Helv , vol.66 , pp. 47-49
    • Gasco, M.R.1    Morel, S.2    Trotta, M.3    Viano, I.4
  • 101
    • 0029930431 scopus 로고    scopus 로고
    • A new microemulsion formulation of Cyclosporine
    • Friman, S.; Backmann, L. A new microemulsion formulation of Cyclosporine. Clin. Pharmacokinet., 1996, 30, 181-193.
    • (1996) Clin. Pharmacokinet , vol.30 , pp. 181-193
    • Friman, S.1    Backmann, L.2
  • 103
    • 0028080167 scopus 로고
    • Potential for Cs A-Neoral in organ transplantation
    • Levy, G.; Grant, D. Potential for Cs A-Neoral in organ transplantation. Transplantation Proceedings., 1994, 26, 2932-2934.
    • (1994) Transplantation Proceedings , vol.26 , pp. 2932-2934
    • Levy, G.1    Grant, D.2
  • 104
    • 0028335905 scopus 로고
    • Reduced inter and intra individual variability in Cyclosporine pharmacokinetics from a microemulsion formulation
    • Kovarik, J.M., Mueller, E.A.; van Bree, J.B.; Tetzloff, W.; Kutz, K. Reduced inter and intra individual variability in Cyclosporine pharmacokinetics from a microemulsion formulation. J. Pharm. Sci., 1994, 83, 444-446.
    • (1994) J. Pharm. Sci , vol.83 , pp. 444-446
    • Kovarik, J.M.1    Mueller, E.A.2    van Bree, J.B.3    Tetzloff, W.4    Kutz, K.5
  • 105
    • 0028329964 scopus 로고
    • Improved dose linearity of Cyclosporine pharmacoki-netics from a microemulsion formulation
    • Mueller, E.A.; Kovarik, J.M.; van Bree, J.B.; Tetzloff, W.; Grevel, J.; Kutz, K. Improved dose linearity of Cyclosporine pharmacoki-netics from a microemulsion formulation. Pharm. Res., 1994, 11, 301-304.
    • (1994) Pharm. Res , vol.11 , pp. 301-304
    • Mueller, E.A.1    Kovarik, J.M.2    van Bree, J.B.3    Tetzloff, W.4    Grevel, J.5    Kutz, K.6
  • 106
    • 0025882648 scopus 로고
    • Microemulsions for improved peptide absorption from the gastrointestinal tract
    • Ritschel, W.A. Microemulsions for improved peptide absorption from the gastrointestinal tract. Meth. Find. Exp. Clin. Pharmacol., 1991, 13, 205-220.
    • (1991) Meth. Find. Exp. Clin. Pharmacol , vol.13 , pp. 205-220
    • Ritschel, W.A.1
  • 107
    • 0025882648 scopus 로고
    • Microemulsions for improved peptide absorption from the gastrointestinal tract
    • Ritschel, W.A. Microemulsions for improved peptide absorption from the gastrointestinal tract. Meth. Find. Exp. Clin. Pharmacol., 1993, 13, 205-220.
    • (1993) Meth. Find. Exp. Clin. Pharmacol , vol.13 , pp. 205-220
    • Ritschel, W.A.1
  • 109
    • 22244443039 scopus 로고    scopus 로고
    • Study on the bioavailability of puerarin from Pueraria lobata isoflavone self-microemulsifying drug-delivery systems and tablets in rabbits by liquid chromatography-mass spectrometry
    • Cui, S.M.; Zhao, C.S.; Tang, X.; Chen, D.W.; He, Z.G. Study on the bioavailability of puerarin from Pueraria lobata isoflavone self-microemulsifying drug-delivery systems and tablets in rabbits by liquid chromatography-mass spectrometry. Biomed. Chromatogra-phy, 2005, 19, 375-8.
    • (2005) Biomed. Chromatogra-phy , vol.19 , pp. 375-378
    • Cui, S.M.1    Zhao, C.S.2    Tang, X.3    Chen, D.W.4    He, Z.G.5
  • 110
    • 24744442330 scopus 로고    scopus 로고
    • Self-microemulsifying drug delivery systems (SMEDDS) for improving in vitro dissolution and oral absorption of Pueraria lobata isofla-vone
    • Cui, S.M.; Zhao, C.S.; Chen, D.W.; He, Z.G. Self-microemulsifying drug delivery systems (SMEDDS) for improving in vitro dissolution and oral absorption of Pueraria lobata isofla-vone. Drug Dev. Ind. Pharm., 2005, 31, 349-56.
    • (2005) Drug Dev. Ind. Pharm , vol.31 , pp. 349-356
    • Cui, S.M.1    Zhao, C.S.2    Chen, D.W.3    He, Z.G.4
  • 112
    • 0036849186 scopus 로고    scopus 로고
    • Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations
    • Kressmann, S.; Biber, A.; Wonnemann, M.; Schug, B.; Blume, H.H.; Muller, W.E. Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations. J. Pharm. Pharmacol., 2002, 54, 1507-14.
    • (2002) J. Pharm. Pharmacol , vol.54 , pp. 1507-1514
    • Kressmann, S.1    Biber, A.2    Wonnemann, M.3    Schug, B.4    Blume, H.H.5    Muller, W.E.6
  • 113
    • 0036231404 scopus 로고    scopus 로고
    • Pharmaceutical quality of different Ginkgo biloba brands
    • Kressmann, S.; Müller, W.E.; Blume, H.H. Pharmaceutical quality of different Ginkgo biloba brands. J. Pharm. Pharmacol., 2002, 54, 661-9.
    • (2002) J. Pharm. Pharmacol , vol.54 , pp. 661-669
    • Kressmann, S.1    Müller, W.E.2    Blume, H.H.3
  • 115
    • 0028194817 scopus 로고
    • Self-emulsifying drug delivery systems (SEDDS) with polyglyco-lyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs
    • Shah, N.H.; Carvajal, M.T.; Patel, C.I; Infeld, M.H.; Malick, A.W. Self-emulsifying drug delivery systems (SEDDS) with polyglyco-lyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. Int. J. Pharm., 1994, 106, 15-23.
    • (1994) Int. J. Pharm , vol.106 , pp. 15-23
    • Shah, N.H.1    Carvajal, M.T.2    Patel, C.I.3    Infeld, M.H.4    Malick, A.W.5
  • 116
    • 1842589355 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of a poorly water soluble drug PNU- 91325 by supersaturable formulations
    • Gao, P.; Guyton, M.E.; Huang, T.; Bauer, J.M.; Stefanski. K.J; Qun, L. Enhanced oral bioavailability of a poorly water soluble drug PNU- 91325 by supersaturable formulations. Drug Dev. Ind. Pharm., 2004, 30, 221-229.
    • (2004) Drug Dev. Ind. Pharm , vol.30 , pp. 221-229
    • Gao, P.1    Guyton, M.E.2    Huang, T.3    Bauer, J.M.4    Stefanski, K.J.5    Qun, L.6
  • 117
    • 0026586447 scopus 로고
    • Self-emulsifying drug delivery systems: Formulation and biopharmaceutical evaluation of an investigational lipophilic compound
    • Charman, S.A.; Charman, W.A.; Rogge, M.C. Self-emulsifying drug delivery systems: formulation and biopharmaceutical evaluation of an investigational lipophilic compound. Pharm Res., 1992, 9, 87-93.
    • (1992) Pharm Res , vol.9 , pp. 87-93
    • Charman, S.A.1    Charman, W.A.2    Rogge, M.C.3
  • 118
    • 0035895309 scopus 로고    scopus 로고
    • Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: Formulation development and bioavailability assessment
    • Kommuru, T.R.; Gurley, B.; Khan, M.A.; Reddy, I.K. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. Int. J. Pharm., 2001, 212, 233-246.
    • (2001) Int. J. Pharm , vol.212 , pp. 233-246
    • Kommuru, T.R.1    Gurley, B.2    Khan, M.A.3    Reddy, I.K.4
  • 119
    • 0028194817 scopus 로고
    • Self-emulsifying drug delivery systems (SEDDS) with polyglyco-lyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs
    • Shah, N.H.; Carjaval, M.T.; Patel, C.I.; Infeld, M.H.; Malick, A.W. Self-emulsifying drug delivery systems (SEDDS) with polyglyco-lyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. Int. J. Pharm., 1994, 106, 15-23.
    • (1994) Int. J. Pharm , vol.106 , pp. 15-23
    • Shah, N.H.1    Carjaval, M.T.2    Patel, C.I.3    Infeld, M.H.4    Malick, A.W.5
  • 120
    • 0033992180 scopus 로고    scopus 로고
    • Enhanced absorption of indomethacin after oral or rectal administration of a self-emulsifying system containing indomethacin to rats
    • Kim, J.Y.; Ku, Y.S. Enhanced absorption of indomethacin after oral or rectal administration of a self-emulsifying system containing indomethacin to rats. Int. J. Pharm., 2000, 174, 81-89.
    • (2000) Int. J. Pharm , vol.174 , pp. 81-89
    • Kim, J.Y.1    Ku, Y.S.2
  • 121
    • 33646854907 scopus 로고    scopus 로고
    • Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system
    • Wu, W.; Wang, Y.; Que, L. Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. Eur. J. Pharm. Biopharm., 2006, 63, 288-294.
    • (2006) Eur. J. Pharm. Biopharm , vol.63 , pp. 288-294
    • Wu, W.1    Wang, Y.2    Que, L.3
  • 122
    • 33748290093 scopus 로고    scopus 로고
    • Preparation and evaluation of self-microemulsifying drug delivery systems (SMEDDS) containing atorvastatin
    • Shen, H.; Zhong, M. Preparation and evaluation of self-microemulsifying drug delivery systems (SMEDDS) containing atorvastatin. J. Pharm. Pharmacol., 2006, 58, 1183-1191.
    • (2006) J. Pharm. Pharmacol , vol.58 , pp. 1183-1191
    • Shen, H.1    Zhong, M.2
  • 123
    • 29244485443 scopus 로고    scopus 로고
    • A new self emulsifying formulation of itroconazole with improved dissolution and oral absorption
    • Hong, J.Y.; Kim, J.K.; Song, Y.K.; Park, J.S.; Kim, C.K. A new self emulsifying formulation of itroconazole with improved dissolution and oral absorption. J. Control. Release., 2006, 110, 332-338.
    • (2006) J. Control. Release , vol.110 , pp. 332-338
    • Hong, J.Y.1    Kim, J.K.2    Song, Y.K.3    Park, J.S.4    Kim, C.K.5
  • 124
    • 33744787859 scopus 로고    scopus 로고
    • Examination of the impact of a range of Pluronic surfactants on the in vitro solubi-lisation behavior and oral bioavailability of lipidic formulations of atovaquone
    • Sek, L.; Boyd, B.J.; Charman, W.N.; Porter, C.J.H. Examination of the impact of a range of Pluronic surfactants on the in vitro solubi-lisation behavior and oral bioavailability of lipidic formulations of atovaquone. J. Pharm. Pharmacol., 2006, 58, 809-820.
    • (2006) J. Pharm. Pharmacol , vol.58 , pp. 809-820
    • Sek, L.1    Boyd, B.J.2    Charman, W.N.3    Porter, C.J.H.4
  • 125
    • 3543106201 scopus 로고    scopus 로고
    • Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations
    • Yap, S.P.; Yuen, K.H. Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. Int. J. Pharm., 2004, 281, 67-78.
    • (2004) Int. J. Pharm , vol.281 , pp. 67-78
    • Yap, S.P.1    Yuen, K.H.2
  • 126
    • 25144440877 scopus 로고    scopus 로고
    • Preparation and evaluation of SEDDS and SMEDDS containing carvedilol
    • Wei, L.; Sun, P.; Nie, S.; Pan, W. Preparation and evaluation of SEDDS and SMEDDS containing carvedilol, Drug Dev. Ind. Pharm., 2005, 31, 785-794.
    • (2005) Drug Dev. Ind. Pharm , vol.31 , pp. 785-794
    • Wei, L.1    Sun, P.2    Nie, S.3    Pan, W.4
  • 127
    • 33645214019 scopus 로고    scopus 로고
    • Disposition of lipid based formulation in the intestinal tract affects the absorption of poorly water soluble drugs
    • Iwanaga, K.; Kushibiki, T.; Miyazaki, M.; Kakemi, M. Disposition of lipid based formulation in the intestinal tract affects the absorption of poorly water soluble drugs. Biol. Pharm. Bull., 2006, 29, 508-512.
    • (2006) Biol. Pharm. Bull , vol.29 , pp. 508-512
    • Iwanaga, K.1    Kushibiki, T.2    Miyazaki, M.3    Kakemi, M.4
  • 128
    • 1842609789 scopus 로고    scopus 로고
    • Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs
    • Kang, B.K.; Lee, J.S.; Chon, S.K.; Jeong, S.Y.; Yuk, S.H.; Khang, G.; Lee, H.B.; Cho, S.H. Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs. Int. J. Pharm., 2004, 274, 65-73.
    • (2004) Int. J. Pharm , vol.274 , pp. 65-73
    • Kang, B.K.1    Lee, J.S.2    Chon, S.K.3    Jeong, S.Y.4    Yuk, S.H.5    Khang, G.6    Lee, H.B.7    Cho, S.H.8
  • 129
    • 0343963156 scopus 로고    scopus 로고
    • Improved bioavail-ability of vitamin E with a self-emulsifying formulation
    • Julianto, T.; Yuen, K.H.; Mohammad Noor, A. Improved bioavail-ability of vitamin E with a self-emulsifying formulation. Int. J. Pharm., 2000, 200, 53-57.
    • (2000) Int. J. Pharm , vol.200 , pp. 53-57
    • Julianto, T.1    Yuen, K.H.2    Mohammad Noor, A.3
  • 130
    • 0028033105 scopus 로고
    • Enhanced absorption of new oral Cyclosporine microemul-sion formulation, Neoral, in liver transplant recipients with external biliary diversion
    • Trull, A.K.; Tan, K.K.C.; Tan, L.; Alexander, G.J.M.; Jamieson, N.V. Enhanced absorption of new oral Cyclosporine microemul-sion formulation, Neoral, in liver transplant recipients with external biliary diversion. Transplant. Proc., 1994, 26, 2977-2978.
    • (1994) Transplant. Proc , vol.26 , pp. 2977-2978
    • Trull, A.K.1    Tan, K.K.C.2    Tan, L.3    Alexander, G.J.M.4    Jamieson, N.V.5
  • 131
    • 0031914282 scopus 로고    scopus 로고
    • Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor
    • Hauss, D.J.; Fogal, S.E.; Ficorilli, J.V.; Price, C.A.; Roy, T.; Jayaraj, A.A.; Keirns, J.J. Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor. J. Pharm. Sci., 1998, 87, 164-169.
    • (1998) J. Pharm. Sci , vol.87 , pp. 164-169
    • Hauss, D.J.1    Fogal, S.E.2    Ficorilli, J.V.3    Price, C.A.4    Roy, T.5    Jayaraj, A.A.6    Keirns, J.J.7
  • 132
    • 2642540226 scopus 로고    scopus 로고
    • Comparative bioavailability study in dogs of a self-emulsifying formulation of progesterone presented in a pellet and liquid form compared with an aqueous suspension of progesterone
    • Tuleu, C.; Newton, M. Rose, J.; Euler, D.; Saklatvala, R. Clarke, A.; Booth, S. Comparative bioavailability study in dogs of a self-emulsifying formulation of progesterone presented in a pellet and liquid form compared with an aqueous suspension of progesterone. J. Pharm. Sci., 2004, 93, 1495-1502.
    • (2004) J. Pharm. Sci , vol.93 , pp. 1495-1502
    • Tuleu, C.1    Newton, M.2    Rose, J.3    Euler, D.4    Saklatvala, R.5    Clarke, A.6    Booth, S.7
  • 133
    • 0035966510 scopus 로고    scopus 로고
    • Preparation and evaluation of biphenyl dimethyl dicarboxylate microemulsions for oral delivery
    • Kim, C.K.; Cho, Y.J.; Gao, Z.G. Preparation and evaluation of biphenyl dimethyl dicarboxylate microemulsions for oral delivery. J. control. Release., 2001, 70, 149-155.
    • (2001) J. Control. Release , vol.70 , pp. 149-155
    • Kim, C.K.1    Cho, Y.J.2    Gao, Z.G.3
  • 134
    • 33745976753 scopus 로고    scopus 로고
    • The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type o/w microemulsion I: Enhancing effects on oral bioavailability of poorly water soluble compounds in rats and beagle dogs
    • Araya, H.; Nagao, S.; Tomita, M.; Hayashi, M. The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type o/w microemulsion I: enhancing effects on oral bioavailability of poorly water soluble compounds in rats and beagle dogs. Drug Metab. Pharmacokinet., 2005, 20, 244-256.
    • (2005) Drug Metab. Pharmacokinet , vol.20 , pp. 244-256
    • Araya, H.1    Nagao, S.2    Tomita, M.3    Hayashi, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.