Enhanced absorption of indomethacin after oral or rectal administration of a self-emulsifying system containing indomethacin to rats

International Journal of Pharmaceutics

Volumn 194, Issue 1, 2000, Pages 81-89

  Kim, Ja Y ^a   Ku, Young S ^a  

^a Ewha Womans University   (South Korea)

Author keywords

Gelatin hollow type rectal suppository; Indomethacin; Rats; SES (Tween 85: ethyl oleate, 3:7)

Indexed keywords

EMULSIFYING AGENT; INDOMETACIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SOLUBILITY; MALE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ADMINISTRATION, RECTAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; EMULSIONS; INDOMETHACIN; INTESTINAL ABSORPTION; MALE; OLEIC ACIDS; POLYSORBATES; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SUPPOSITORIES; SURFACE-ACTIVE AGENTS; VISCOSITY;

EID: 0033992180     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00367-1     Document Type: Article

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