Disposition of lipid-based formulation in the intestinal tract affects the absorption of poorly water-soluble drugs

Biological and Pharmaceutical Bulletin

Volumn 29, Issue 3, 2006, Pages 508-512

  Iwanaga, Kazunori ^a   Kushibiki, Toshihiro ^a   Miyazaki, Makoto ^a   Kakemi, Masawo ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Intestinal absorption; Lipid based formulation; Poorly water soluble drug; Self microemulsifying drug delivery system

Indexed keywords

ANTHRAQUINONE DERIVATIVE; BILE SALT; CHYLOMICRON; GELUCIRE; INTRALIPID; SOVENT GREEN 3; SOYBEAN OIL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; INTESTINE ABSORPTION; MALE; MICELLE; MICROEMULSION; NONHUMAN; PROTEIN SYNTHESIS; RAT;

ANIMALS; ANTHRAQUINONES; AREA UNDER CURVE; BILE ACIDS AND SALTS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHYLOMICRONS; COLCHICINE; DATA INTERPRETATION, STATISTICAL; EMULSIONS; INTESTINAL ABSORPTION; LIPASE; LIPIDS; MALE; MICELLES; PHARMACEUTICAL PREPARATIONS; RATS; RATS, WISTAR; SOLUBILITY; SOYBEAN OIL;

EID: 33645214019     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.29.508     Document Type: Article

References (18)

1. Lipinski C. A., Lombardo F., Dominy B. W., Feeney P. J., Adv. Drug Delivery Rev., 23, 3-25 (1997).
2. Leuner C., Dressman J., Eur. J. Pharm. Biopharm., 50, 47-60 (2000).
3. Gaspari F., Anedda M. F., Signorini O., Amuchastegui S. C., Perico N., Remuzzi G., Transplant. Proc., 30, 1654-1655 (1998).
4. Subramanian N., Ghosal S. K., Indian J. Exp. Biol., 42, 1056-1065 (2004).
5. Constantinides P. P., Welzel G., Ellens H., Smith P. L., Sturgis S., Yiv S. H., Owen A. B., Pharm. Res., 13, 210-215 (1996).
6. Kovarik J. M., Mueller E. A., Bree J. B., Tetzloff W., Kutz K., J. Pharm. Sci., 83, 444-446 (1994).
7. Porter C. J. H., Charman S. A., Charman W. N., J. Pharm. Sci., 85, 351-356 (1996).
8. Nishihata T., Yamamoto K., Ishizawa M., J. Pharm. Pharmacol., 45, 947-950 (1993).
9. Glickman R. M., Perrotto J. L., Kirsch K., Gastroenterology, 70, 347-352 (1976).
10. Arreaza-Plaza A. A., Bosch V., Otayek M. A., Biochim. Biophys. Acta, 431, 297-302 (1976).
11. Liu H. X., Adachi I., Horikoshi I., Ueno M., Int. J. Pharm., 118, 55-64 (1995).
12. Hauss D. J., Fogal S. E., Ficorilli J. V., Price C. A., Roy T., Jayaraj A. A., Keirins J. J., J. Pharm. Sci., 87, 164-169 (1998).
13. Subramanian N., Ray S., Ghosal S. K., Bhadra R., Moulik S. P., Biol. Pharm. Bull., 27, 1993-1999 (2004).
14. Kang B. K., Lee J. S., Chon S. K., Jeong S. Y., Yuk S. H., Khang G., Lee H. B., Cho S. H., Int. J. Pharm., 274, 65-73 (2004).
15. Yang S., Gursoy R. N., Lambert G., Benita S., Pharm. Res., 21, 261-270 (2004).
16. Hussain M. M., Atherosclerosis, 148, 1-15 (2000).
17. de Smidt P. C., Campanero M. A., Troconiz I. F., Int. J. Pharm., 270, 109-118 (2004).
18. McDonald G. B., Weidman M., Quart. J. Exp. Physiol., 72, 153-159 (1987).