-
1
-
-
15744368796
-
Physiological, pharmacological and clinical features of the multidrug resistance protein 2
-
DOI 10.1016/j.biopha.2005.01.005
-
Fardel O., Jigorel E., Le Vee M., Payen L., Physiological, pharmacological and clinical features of the multidrug resistance protein 2 Biomedicine and Pharmacotherapy 2005 59 3 104 114 (Pubitemid 40417519)
-
(2005)
Biomedicine and Pharmacotherapy
, vol.59
, Issue.3
, pp. 104-114
-
-
Fardel, O.1
Jigorel, E.2
Le Vee, M.3
Payen, L.4
-
2
-
-
38349126398
-
Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver
-
Ahmed S., Vo N. T., Thalhammer T., Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver Journal of Pharmacy and Pharmacology 2008 60 55 62
-
(2008)
Journal of Pharmacy and Pharmacology
, vol.60
, pp. 55-62
-
-
Ahmed, S.1
Vo, N.T.2
Thalhammer, T.3
-
3
-
-
27544466823
-
- rats
-
DOI 10.1124/dmd.105.006262
-
Kivisto K. T., Grisk O., Hofmann U., Disposition of oral and intravenous pravastatin in MRP2-deficient TR-rats Drug Metabolism and Disposition 2005 33 1593 1596 (Pubitemid 41539954)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.11
, pp. 1593-1596
-
-
Kivisto, K.T.1
Grisk, O.2
Hofmann, U.3
Meissner, K.4
Moritz, K.-U.5
Ritter, C.6
Arnold, K.A.7
Lutjohann, D.8
Von Bergmann, K.9
Kloting, I.10
Eichelbaum, M.11
Kroemer, H.K.12
-
4
-
-
34249023089
-
Effect of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4- ylmethoxy) phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide], a human tumor necrosis factor α-converting enzyme inhibitor, on the disposition of methotrexate: A transporter-based drug-drug interaction case study
-
DOI 10.1124/dmd.106.013946
-
Luo G., Garner C. E., Xiong H., Effect of DPC 333 [(2R)-2-{(3R)-3-amino- 3-[4-(2-methylquinolin-4-ylmethoxy) phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4- methylpentanamide], a human tumor necrosis factor -converting enzyme inhibitor, on the disposition of methotrexate: a transporter-based drug-drug interaction case study Drug Metabolism and Disposition 2007 35 835 840 (Pubitemid 46798593)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.6
, pp. 835-840
-
-
Luo, G.1
Garner, C.E.2
Xiong, H.3
Hu, H.4
Richards, L.E.5
Brouwer, K.L.R.6
Duan, J.7
Decicco, C.P.8
Maduskuie, T.9
Shen, H.10
Lee, F.W.11
Gan, L.-S.12
-
5
-
-
48149098366
-
The impact of P-glycoprotein and Mrp2 on mycophenolic acid levels in mice
-
Wang J., Figurski M., Shaw L. M., Burckart G. J., The impact of P-glycoprotein and Mrp2 on mycophenolic acid levels in mice Transplant Immunology 2008 19 3-4 192 196
-
(2008)
Transplant Immunology
, vol.19
, Issue.34
, pp. 192-196
-
-
Wang, J.1
Figurski, M.2
Shaw, L.M.3
Burckart, G.J.4
-
6
-
-
68549104491
-
Role of multidrug-resistance protein 2 in coproporphyrin transport: Results from experimental studies in bile fistula rat models
-
Moriondo V., Marchini S., Di Gangi P., Ferrari M. C., Nascimbeni F., Rocchi E., Ventura P., Role of multidrug-resistance protein 2 in coproporphyrin transport: results from experimental studies in bile fistula rat models Cellular and Molecular Biology 2009 55 2 70 78
-
(2009)
Cellular and Molecular Biology
, vol.55
, Issue.2
, pp. 70-78
-
-
Moriondo, V.1
Marchini, S.2
Di Gangi, P.3
Ferrari, M.C.4
Nascimbeni, F.5
Rocchi, E.6
Ventura, P.7
-
7
-
-
0000552161
-
Chronic idiopathic jaundice with unidentified pigment in liver cells; A new clinicopathologic entity with a report of 12 cases
-
Dubin I. N., Johnson F. B., Chronic idiopathic jaundice with unidentified pigment in liver cells; a new clinicopathologic entity with a report of 12 cases Medicine 1954 33 3 155 197
-
(1954)
Medicine
, vol.33
, Issue.3
, pp. 155-197
-
-
Dubin, I.N.1
Johnson, F.B.2
-
8
-
-
0030768373
-
The canalicular multidrug resistance protein, cMRP/MRP2, a novel conjugate export pump expressed in the apical membrane of hepatocytes
-
DOI 10.1016/S0065-2571(96)00013-1, PII S0065257196000131
-
Keppler D., Knig J., Bchler M., The canalicular multidrug resistance protein, cMRP/MRP2, a novel conjugate export pump expressed in the apical membrane of hepatocytes Advances in Enzyme Regulation 1997 37 321 333 (Pubitemid 27371566)
-
(1997)
Advances in Enzyme Regulation
, vol.37
, pp. 321-333
-
-
Keppler, D.1
Konig, J.2
Buchler, M.3
-
9
-
-
0025325922
-
Diagnostic and pathogenetic implications of urinary coproporphyrin excretion in the Dublin-Johnson Syndrome
-
Frank M., Doss M., De Carvalho D. G., Diagnostic and pathogenetic implications of urinary coproporphyrin excretion in the dublin-johnson syndrome Hepato-Gastroenterology 1990 37 1 147 151 (Pubitemid 20092226)
-
(1990)
Hepato-Gastroenterology
, vol.37
, Issue.1
, pp. 147-151
-
-
Frank, M.1
Doss, M.2
De Carvalho, D.G.3
-
10
-
-
0033361943
-
Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP- binding-cassette region in Dubin-Johnson syndrome
-
DOI 10.1086/302292
-
Toh S., Wada M., Uchiumi T., Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome The American Journal of Human Genetics 1999 64 739 746 (Pubitemid 30460416)
-
(1999)
American Journal of Human Genetics
, vol.64
, Issue.3
, pp. 739-746
-
-
Toh, S.1
Wada, M.2
Uchiumi, T.3
Inokuchi, A.4
Makino, Y.5
Horie, Y.6
Adachi, Y.7
Sakisaka, S.8
Kuwano, M.9
-
13
-
-
0035103009
-
Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
-
DOI 10.1097/00008571-200103000-00008
-
Ito S., Ieiri I., Tanabe M., Suzuki A., Higuchi S., Otsubo K., Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects Pharmacogenetics 2001 11 2 175 184 (Pubitemid 32216128)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.2
, pp. 175-184
-
-
Ito, S.1
Ieiri, I.2
Tanabe, M.3
Suzuki, A.4
Higuchi, S.5
Otsubo, K.6
-
14
-
-
0037131880
-
Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): Its impact on drug disposition
-
DOI 10.1016/S0169-409X(02)00075-3, PII S0169409X02000753
-
Suzuki H., Sugiyama Y., Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition Advanced Drug Delivery Reviews 2002 54 1311 1331 (Pubitemid 35284255)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.10
, pp. 1311-1331
-
-
Suzuki, H.1
Sugiyama, Y.2
-
15
-
-
33750958330
-
High-dose methotrexate in pediatric acute lymphoblastic leukemia: Impact of ABCC2 polymorphisms on plasma concentrations
-
DOI 10.1016/j.clpt.2006.08.012, PII S0009923606003481
-
Rau T., Erney B., Gres R., Eschenhagen T., Beck J., Langer T., High-dose methotrexate in pediatric acute lymphoblastic leukemia: impact of ABCC2 polymorphisms on plasma concentrations Clinical Pharmacology and Therapeutics 2006 80 468 476 (Pubitemid 44737489)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.80
, Issue.5
, pp. 468-476
-
-
Rau, T.1
Erney, B.2
Gores, R.3
Eschenhagen, T.4
Beck, J.5
Langer, T.6
-
16
-
-
33750346955
-
Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients
-
DOI 10.1097/01.tp.0000235533.29300.e7, PII 0000789020061027000012
-
Naesens M., Kuypers D. R. J., Verbeke K., Vanrenterghem Y., Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients Transplantation 2006 82 1074 1084 (Pubitemid 44632124)
-
(2006)
Transplantation
, vol.82
, Issue.8
, pp. 1074-1084
-
-
Naesens, M.1
Kuypers, D.R.J.2
Verbeke, K.3
Vanrenterghem, Y.4
-
17
-
-
33846012498
-
Irinotecan-induced diarrhea: Functional significance of the polymorphic ABCC2 transporter protein
-
DOI 10.1038/sj.clpt.6100019, PII 6100019
-
de Jong F. A., Scott-Horton T. J., Kroetz D. L., McLeod H. L., Friberg L. E., Mathijssen R. H., Verweij J., Marsh S., Sparreboom A., Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein Clinical Pharmacology and Therapeutics 2007 81 42 49 (Pubitemid 46050866)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.1
, pp. 42-49
-
-
De Jong, F.A.1
Scott-Horton, T.J.2
Kroetz, D.L.3
McLeod, H.L.4
Friberg, L.E.5
Mathijssen, R.H.6
Verweij, J.7
Marsh, S.8
Sparreboom, A.9
-
18
-
-
33846034416
-
Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans
-
DOI 10.1007/s11095-006-9159-2
-
Kivist K. T., Niemi M., Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans Pharmaceutical Research 2007 24 239 247 (Pubitemid 46072183)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.2
, pp. 239-247
-
-
Kivisto, K.T.1
Niemi, M.2
-
19
-
-
33644876141
-
NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity
-
DOI 10.1161/CIRCULATIONAHA.105.576850, PII 0000301720051213000015
-
Wojnowski L., Kulle B., Schirmer M., Schlter G., Schmidt A., Rosenberger A., Vonhof S., Bickebller H., Toliat M. R., Suk E. -K., Tzvetkov M., Kruger A., Seifert S., Kloess M., Hahn H., Loeffler M., Nrnberg P., Pfreundschuh M., Trmper L., Brockmller J., Hasenfuss G., NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity Circulation 2005 112 24 3754 3762 (Pubitemid 43739516)
-
(2005)
Circulation
, vol.112
, Issue.24
, pp. 3754-3762
-
-
Wojnowski, L.1
Kulle, B.2
Schirmer, M.3
Schluter, G.4
Schmidt, A.5
Rosenberger, A.6
Vonhof, S.7
Bickeboller, H.8
Toliat, M.R.9
Suk, E.-K.10
Tzvetkov, M.11
Kruger, A.12
Seifert, S.13
Kloess, M.14
Hahn, H.15
Loeffler, M.16
Nurnberg, P.17
Pfreundschuh, M.18
Trumper, L.19
Brockmoller, J.20
Hasenfuss, G.21
more..
-
20
-
-
72149105912
-
Quantification of coproporphyrin isomers i and III in urine by HPLC and determination of their ratio for investigations of multidrug resistance protein 2 (MRP2) function in humans
-
Respaud R., Benz-de Bretagne I., Blasco H., Hulot J. S., Lechat P., Le Guellec C., Quantification of coproporphyrin isomers I and III in urine by HPLC and determination of their ratio for investigations of multidrug resistance protein 2 (MRP2) function in humans Journal of Chromatography B 2009 877 30 3893 3898
-
(2009)
Journal of Chromatography B
, vol.877
, Issue.30
, pp. 3893-3898
-
-
Respaud, R.1
Benz-De Bretagne, I.2
Blasco, H.3
Hulot, J.S.4
Lechat, P.5
Le Guellec, C.6
-
21
-
-
33847249931
-
Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex
-
DOI 10.1038/sj.tpj.6500403, PII 6500403
-
Haenisch S., Zimmermann U., Dazert E., Wruck C. J., Dazert P., Siegmund S., Kroemer H. K., Warzok R. W., Cascorbi I., Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex Pharmacogenomics Journal 2007 7 1 56 65 (Pubitemid 46322080)
-
(2007)
Pharmacogenomics Journal
, vol.7
, Issue.1
, pp. 56-65
-
-
Haenisch, S.1
Zimmermann, U.2
Dazert, E.3
Wruck, C.J.4
Dazert, P.5
Siegmund, S.6
Kroemer, H.K.7
Warzok, R.W.8
Cascorbi, I.9
-
22
-
-
3543004158
-
Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2
-
DOI 10.1023/B:PHAM.0000026422.06207.33
-
Hirouchi M., Suzuki H., Itoda M., Ozawa S., Sawada J. -I., Ieiri I., Ohtsubo K., Sugiyama Y., Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2 Pharmaceutical Research 2004 21 5 742 748 (Pubitemid 39011294)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.5
, pp. 742-748
-
-
Hirouchi, M.1
Suzuki, H.2
Itoda, M.3
Ozawa, S.4
Sawada, J.-I.5
Ieiri, I.6
Ohtsubo, K.7
Sugiyama, Y.8
-
23
-
-
22344452418
-
Variable expression of MRP2 (ABCC2) in human placenta: Influence of gestational age and cellular differentiation
-
DOI 10.1124/dmd.104.003335
-
Meyer Zu Schwabedissen H. E., Jedlitschky G., Gratz M., Haenisch S., Linnemann K., Fusch C., Cascorbi I., Kroemer H. K., Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation Drug Metabolism and Disposition 2005 33 7 896 904 (Pubitemid 41002769)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.7
, pp. 896-904
-
-
Meyer Zu Schwabedissen, H.E.1
Jedlitschky, G.2
Gratz, M.3
Haenisch, S.4
Linnemann, K.5
Fusch, C.6
Cascorbi, I.7
Kroemer, H.K.8
-
24
-
-
33845226137
-
Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy
-
Izzedine H., Hulot J. S., Villard E., Goyenvalle C., Dominguez S., Ghosn J., Valentin M. A., Lechat P., Deray G., Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy Journal of Infectious Diseases 2006 194 11 1481 1491 (Pubitemid 44851889)
-
(2006)
Journal of Infectious Diseases
, vol.194
, Issue.11
, pp. 1481-1491
-
-
Izzedine, H.1
Hulot, J.-S.2
Villard, E.3
Goyenvalle, C.4
Dominguez, S.5
Ghosn, J.6
Valentin, M.A.7
Lechat, P.8
Deray, G.9
-
25
-
-
34249662218
-
A new JAVA interface implementation of THESIAS: Testing haplotype effects in association studies
-
DOI 10.1093/bioinformatics/btm058
-
Tregouet D. A., Garelle V., A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies Bioinformatics 2007 23 8 1038 1039 (Pubitemid 47050595)
-
(2007)
Bioinformatics
, vol.23
, Issue.8
, pp. 1038-1039
-
-
Tregouet, D.A.1
Garelle, V.2
-
26
-
-
33644770013
-
MRP2 and 3 in health and disease
-
DOI 10.1016/j.canlet.2005.05.051, PII S0304383505009250, Pharmacogenomics in Cancer Chemotherapy: Recent Advances in Drug Transporters and Genome Analysis
-
Borst P., Zelcer N., Van De Wetering K., MRP2 and 3 in health and disease Cancer Letters 2006 234 1 51 61 (Pubitemid 43343940)
-
(2006)
Cancer Letters
, vol.234
, Issue.1
, pp. 51-61
-
-
Borst, P.1
Zelcer, N.2
Van De Wetering, K.3
-
27
-
-
0034928631
-
Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver
-
DOI 10.1053/jhep.2001.26213
-
Donner M. G., Keppler D., Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver Hepatology 2001 34 2 351 359 (Pubitemid 32702348)
-
(2001)
Hepatology
, vol.34
, Issue.2
, pp. 351-359
-
-
Donner, M.G.1
Keppler, D.2
-
28
-
-
0030963906
-
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis
-
DOI 10.1016/S0016-5085(97)70103-3
-
Trauner M., Arrese M., Soroka C. J., Ananthanarayanan M., Koeppel T. A., Schlosser S. F., Suchy F. J., Keppler D., Boyer J. L., The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis Gastroenterology 1997 113 1 255 264 (Pubitemid 27281782)
-
(1997)
Gastroenterology
, vol.113
, Issue.1
, pp. 255-264
-
-
Trauner, M.1
Arrese, M.2
Soroka, C.J.3
Ananthanarayanan, M.4
Koeppel, T.A.5
Schlosser, S.F.6
Suchy, F.J.7
Keppler, D.8
Boyer, J.L.9
-
29
-
-
79959503826
-
The international hapmap project
-
The international hapmap project Nature 2003 426 789 796
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
30
-
-
78649320874
-
Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function
-
Laechelt S., Turrini E., Ruehmkorf A., Siegmund W., Cascorbi I., Haenisch S., Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function Pharmacogenomics Journal 2011 11 1 25 34
-
(2011)
Pharmacogenomics Journal
, vol.11
, Issue.1
, pp. 25-34
-
-
Laechelt, S.1
Turrini, E.2
Ruehmkorf, A.3
Siegmund, W.4
Cascorbi, I.5
Haenisch, S.6
-
31
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
DOI 10.1126/science.1135308
-
Kimchi-Sarfaty C., Oh J. M., Kim I. W., A silent polymorphism in the MDR1 gene changes substrate specificity Science 2007 315 525 528 (Pubitemid 46175758)
-
(2007)
Science
, vol.315
, Issue.5811
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.-W.3
Sauna, Z.E.4
Calcagno, A.M.5
Ambudkar, S.V.6
Gottesman, M.M.7
-
32
-
-
19544391975
-
A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups
-
DOI 10.1093/hmg/ddh273
-
Capon F., Allen M. H., Ameen M., Burden A. D., Tillman D., Barker J. N., Trembath R. C., A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups Human Molecular Genetics 2004 13 20 2361 2368 (Pubitemid 39377840)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.20
, pp. 2361-2368
-
-
Capon, F.1
Allen, M.H.2
Ameen, M.3
Burden, A.D.4
Tillman, D.5
Barker, J.N.6
Trembath, R.C.7
-
33
-
-
33845899137
-
Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure
-
DOI 10.1126/science.1131262
-
Nackley A. G., Shabalina S. A., Tchivileva I. E., Satterfield K., Korchynskyi O., Makarov S. S., Maixner W., Diatchenko L., Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure Science 2006 314 5807 1930 1933 (Pubitemid 46026115)
-
(2006)
Science
, vol.314
, Issue.5807
, pp. 1930-1933
-
-
Nackley, A.G.1
Shabalina, S.A.2
Tchivileva, I.E.3
Satterfield, K.4
Korchynskyi, O.5
Makarov, S.S.6
Maixner, W.7
Diatchenko, L.8
-
34
-
-
0032745443
-
The human multidrug resistance protein 2 gene: Functional characterization of the 5'-flanking region and expression in hepatic cells
-
Tanaka T., Uchiumi T., Hlnoshlta E., Inokuchi A., Toh S., Wada M., Takano H., Kohno K., Kuwano M., The human multidrug resistance protein 2 gene: functional characterization of the 5'-flanking region and expression in hepatic cells Hepatology 1999 30 6 1507 1512
-
(1999)
Hepatology
, vol.30
, Issue.6
, pp. 1507-1512
-
-
Tanaka, T.1
Uchiumi, T.2
Hlnoshlta, E.3
Inokuchi, A.4
Toh, S.5
Wada, M.6
Takano, H.7
Kohno, K.8
Kuwano, M.9
|