Quantification of coproporphyrin isomers I and III in urine by HPLC and determination of their ratio for investigations of Multidrug Resistance Protein 2 (MRP2) function in humans

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 30, 2009, Pages 3893-3898

  Respaud, Renaud ^a   Benz de Bretagne, Isabelle ^a,b   Blasco, Helene ^a,c,d   Hulot, Jean Sébastien ^e   Lechat, Philippe ^e   Le Guellec, Chantal ^a,c  

^a UNIVERSITY HOSPITAL OF TOURS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ DE TOURS   (France)

^d CNRS   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

ATP binding cassette transporters; Biological markers; Coproporphyrins; High performance liquid chromatography; Multidrug Resistance associated Protein 2

Indexed keywords

ACETATE BUFFERS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL MARKERS; CALIBRATION CURVES; CHROMATOGRAPHIC SEPARATIONS; CLINICAL STUDY; CONCENTRATION RANGES; CORRELATION COEFFICIENT; FLUORESCENCE DETECTION; LOWER LIMIT OF QUANTIFICATIONS; MOBILE PHASE; MULTIDRUG RESISTANCE; QUANTITATIVE DETERMINATIONS;

ACETONITRILE; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; LIQUIDS; PORPHYRINS; PROTEINS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

ACETIC ACID; ACETONITRILE; COPROPORPHYRIN; COPROPORPHYRIN I; COPROPORPHYRIN II; MULTIDRUG RESISTANCE PROTEIN 2; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CALIBRATION; DEVICE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE ASSAY; URINALYSIS; VALIDATION PROCESS;

ADULT; AGED; AGED, 80 AND OVER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COPROPORPHYRINS; FEMALE; HUMANS; ISOMERISM; MALE; MIDDLE AGED; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; YOUNG ADULT;

EID: 72149105912     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.09.047     Document Type: Article

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