Analysis of postmortem ventricular cerebrospinal fluid from patients with and without dementia indicates association of vitamin e with neuritic plaques and specific measures of cognitive performance

Journal of Alzheimer's Disease

Volumn 24, Issue 4, 2011, Pages 767-774

  Hensley, Kenneth ^a   Barnes, Lisa L ^b   Christov, Alexandar ^a   Tangney, Christy ^c   Honer, William G ^d   Schneider, Julie A ^b   Bennett, David A ^b   Morris, Martha Clare ^c  

^a UNIVERSITY OF TOLEDO MEDICAL CENTER   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Alzheimer's disease; cerebrospinal fluid; Religious Orders Study; tocopherol; vitamin E

Indexed keywords

ALPHA TOCOPHEROL; APOLIPOPROTEIN E4; GAMMA TOCOPHEROL;

AGE; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN TISSUE; CEREBROSPINAL FLUID; COGNITION; DEATH; DEMENTIA; DISEASE ASSOCIATION; EDUCATIONAL STATUS; EPISODIC MEMORY; FEMALE; GENDER; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL PERFORMANCE; NEUROFIBRILLARY TANGLE; PERCEPTION; POSTMORTEM INTERVAL; PRIORITY JOURNAL; SENILE PLAQUE; VENTRICULAR CEREBROSPINAL FLUID;

EID: 79959257484     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-101995     Document Type: Article

References (38)

1. Hensley K, Benaksas EJ, Bolli R, Comp P, Grammas P, Hamdheydari L, Mou S, Pye QN, Stoddard MF, Wallis G, Williamson KS,West M,Wechter WJ, Floyd RA (2004) New perspectives on vitamin E:-tocopherol and carboxyethylhydroxychroman metabolites in biology and medicine. Free Radic Biol Med 36, 1-15. (Pubitemid 38068287)
2. Lehman J, Martin HL, Lashley EL, Marshall MW, Judd JT (1986) Vitamin E in foods from high and low linoleic acid diets. J Am Diet Assoc 86, 1208-1216. (Pubitemid 16032214)
3. Traber MG, Burton GW, Hughes L, Ingold KU, Hidaka H, Mallowy M, Kane J, Hyams J, Kayden HJ (1992) Discrimina tion between forms of vitamin E by humans with and without genetic abnormalities of lipoprotein metabolism. J Lipid Res 33, 1171-1182.
4. Morris MC, EvansDA, Bienias JL, Tangney CC, BennettDA, Aggarwal N, Wilson RS, Scherr PA (2002) Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA 287, 3230-3237. (Pubitemid 34686104)
5. Larrieu S, Latenneur L, Helmer C, Dartigues JF, Barberger-Gateau P (2004) Nutritional factors and risk of incident dementia in the PAQUID longitudinal cohort. J Nutr Health Aging 8, 150-154. (Pubitemid 38667939)
6. Morris MC, Evans DA, Tangney CC, Bienias JL,Wilson RS, Aggarwal NT, Scherr PA (2005) Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr 81, 508-514. (Pubitemid 43073356)
7. Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hoffman A,Witteman JC, BretelerMM(2002) Dietary intake of antioxidants and risk of Alzheimers disease. JAMA 287, 3223-3229. (Pubitemid 34686103)
8. Sano M, Ernesto C, thosmas RG, Klauber MR, Schafer K, Grundman M,Woodbury P, Growdon J, CotmanCW, Pfeiffer E, Schneider LS, Thal LJ (1997) A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimers disease: The Alzheimers Disease Cooperative Study. N Engl J Med 336, 1216-1227.
9. Isaac MGEKN, Quinn R, Tabet N (2008) Vitamin E for Alzheimers disease and mild cognitive impairment. Cochrane Database Syst Rev 16, CD002854, 1-24.
10. Lloret A, Badia MC,Mora NJ, Pallardo FV, Alonso MD,Vina J (2009) Vitamin E paradox in Alzheimers disease: it does not prevent loss of cognition and may even be detrimental. J Alzheimers Dis 17, 143-149.
11. Handelman GJ, Machlin LM, Fitch K, Weiter JJ, Dratz EA (1985) Oral-tocopherol supplements decrease plasma-tocopherol levels in humans. J Nutr 115, 807-813.
12. Jiang Q, Elson-Schwab I, Courtemanche C, Ames BN (2000)-Tocopherol and its major metabolite, in contrast to a-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proc Natl Acad Sci U S A 97, 11494-11499.
13. Jiang Q, Ames BN (2003)-Tocopherol, but not-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats. FASEB J 17, 816-822. (Pubitemid 36538656)
14. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, Mordan L (1993)-Tocopherol detoxification of nitrogen dioxide: Superiority to-tocopherol. Proc Natl Acad ScUS A 90, 1771-1775. (Pubitemid 23069938)
15. Engelhart MJ, Ruitenberg A,Meijer J, Kilaan A, van Swieten JC, Hofman A, Witteman JC, Breteler MM (2005) Plasma levels of antioxidants are not associated with Alzheimers disease or cognitive decline. Dement Geriatr Cogn Disord 19, 134-139. (Pubitemid 40868040)
16. Ravaglia G, Forti P, Lucicesare A, Pisacane N, Rietti E, Mangialasche F, Cecchetti R, Patterson C, Mecocci P (2008) Plasma tocopherols and risk of cognitive impairment in an elderly Italian cohort. Am J Clin Nutr 87, 1306-1313. (Pubitemid 351679774)
17. Jimenez-Jimenez FJ, de Bustos F, Molina JA, Benito-Leon J, Tallon-Barranco A, Gasalla T, Orti-Pareja M, Guillamon F, Rubio JC, Arenas J, Enriquez-de-Salamanca R (1997) Cerebrospinal fluid levels of alpha-tocopherol (vitamin E) in Alzheimers disease. Neural Transm 104, 703-710. (Pubitemid 27474683)
18. Williamson KS, Gabbita SP, Mou S, West M, Pye QN, Markesbery WR, Cooney RV, Grammas P, Reimann-Philipp U, Floyd RA, HensleyK(2002) The nitration product 5-nitrogamma-tocopherol is increased in the Alzheimer brain. Nitric Oxide Biol Chem 6, 222-227.
19. Bennett DA, Wilson RS, Schneider JA, Evans DA, Beckett LA, Aggarwall NT, Barnes LL, Fox JH, Bach J (2002) The natural history of mild cognitive impairment in older persons. Neurology 59, 198-205. (Pubitemid 34779177)
20. Schneider JA, Aggarwal NT, Barnes L, Boyle P, Bennett DA (2009) The neuropathology of older persons with and without dementia from community versus clinic cohorts. J Alzheimers Dis 18, 691-701
21. Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G, Mellits ED, Clark C (1989) The consortium to establish a registry for Alzheimers disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimers disease. Neurology 39, 1159-1165. (Pubitemid 19239715)
22. Barnes LL,Wilson RS, Bienias JL, Schneider JA, Evans DA, Bennett DA (2005) Sex differences in the clinical manifestations of Alzheimer disease pathology. Arch Gen Psychiatry 62, 685-692.
23. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimers disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimers Disease. Neurology 34, 939-944. (Pubitemid 14076461)
24. Buchman AS, Boyle PA, Wilson RS, Beck TL, Kelly JF, Bennett DA (2009) Apolipoprotein E e4 allele is associated with more rapid motor decline in older persons. Alzheimer Dis Assoc Disord 23, 63-69.
25. Medispan Inc (1995) Master Drug Database (MDDB) Documentation Manual, Medispan Inc, Indianapolis, IN.
26. Wilson RS, Mendes De Leon CF, Barnes LL, Schneider JA, Bienias JL, EvanDA, BennettDA(2002) Participation in cognitively stimulating activities and risk of incident Alzheimer disease. JAMA 287, 742-748. (Pubitemid 34250460)
27. Wilson RS, Beckett LA, Barnes LL, Schneider JA, Bach J, Evans DA, Bennett DA (2002) Individual differences in rates of change in cognitive abilities of older persons. Psychol Aging 17, 179-193. (Pubitemid 34568635)
28. Mirra SS, Heyman A,McKeel D, Sumi SM, Crain BJ, Bronlee LM, Vogel FS, Hughes JP, van Belle G, Berg L (1991) The consortium to establish a registry for Alzheimers disease (CERAD). Part II. Standardization of the neuropathological assessment of Alzheimers disease. Neurology 41, 479-486.
29. Braak H, Braak E (1991) Neuropathological staging of Alzheimer-related changes. Acta Neuropathol (Berl) 82, 239-259.
30. Consensus recommendations for the postmortem diagnosis of Alzheimers disease (1997) The National Institute on Aging, and Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimers disease. Neurobiol Aging 18(4 Suppl), S1-S2.
31. Schneider JA,Wilson RS, Cochran EJ, Bienias JL, Arnold SE, Evans DA, Bennet DA (2003) Relation of cerebral infarctions to dementia and cognitive function in older persons. Neurology 60, 1082-1088. (Pubitemid 36418764)
32. Schneider JA, Arvanitakis Z, Leurgans SE, BennettDA(2009) The neuropathology of probable Alzheimers disease and mild cognitive impairment. Ann Neurol 66, 200-208.
33. Mangialasche F, Kivipelto M, Mecocci P, Rizzuto D, Palmer K,Winblad B, Fratiglioni L (2010) High plasma levels of vitaminEforms and reduced Alzheimers disease risk in advanced age. J Alzheimers Dis 20, 1029-1037.
34. Vatassery GT, Nelson MJ, Maletta GJ, Kuskowski MA (1991) Vitamin E (tocopherols) in human cerebrospinal fluid. Am J Clin Nutr 53, 95-99. (Pubitemid 21917615)
35. Vatassery GT, Adityanjee, Quach HT, Smith WE, Kuskowski MA, MelnykD(2004) Alpha and gamma tocopherols in cerebrospinal Fuid and serum from older, male, human subjects. J Am Coll Nutr 23, 233-238. (Pubitemid 38746112)
36. Pappert EJ, Tangney CC, Goetz CG, Ling ZD, Lipton JW, Stebbins GT, Carvey PM (1996) Alpha-tocopherol in the ventricular cerebrospinal fluid of Parkinsons disease patients: Dose-response study and correlations with plasma levels. Neurology 47, 1037-1042.
37. Tohgi H, Abe T, Nakanishi M, Manato F, Sasaki K, Takahashi S (1994) Concentrations of alpha-tocopherol and its quinine derivative in cerebrospinal fluid from patients with vascular dementia of the Binswanger type and Alzheimer type dementia. Neurosci Lett 174, 73-76.
38. Schippling S,Kontush A, Arlt S, Buhmann C, Sturenburg HG, Mann U, Muller-Thomsen T, Beisiegel U (2000) Increased lipoprotein oxidation in Alzheimers disease. Free Radic Biol Med 28, 351-360. (Pubitemid 30110650)