A common biosynthetic pathway governs the dimerization and secretion of inhibin and related transforming growth factor β(TGFβ) ligands

Journal of Biological Chemistry

Volumn 284, Issue 14, 2009, Pages 9311-9320

  Walton, Kelly L ^a   Makanji, Yogeshwar ^a,b   Wilce, Matthew C ^b   Chan, Karen L ^a   Robertson, David M ^a   Harrison, Craig A ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING INTERFACE; BIOSYNTHETIC PATHWAY; CONVEX SURFACES; HETERODIMER; HOMOLOGY MODELING; HYDROPHOBIC INTERFACE; HYDROPHOBIC MOTIFS; HYDROPHOBIC PACKING; HYDROPHOBIC RESIDUES; IN-VITRO; NON-COVALENT INTERACTION; PROPEPTIDE; REGULATORY MECHANISM; SIDE CHAINS; TRANSFORMING GROWTH FACTORS;

BIOACTIVITY; BIOSYNTHESIS; DIMERIZATION; GLYCOPROTEINS; HYDROPHOBICITY; PEPTIDES;

LIGANDS;

ACTIVIN A; ALANINE; HETERODIMER; INHIBIN; INHIBIN A; ISOLEUCINE; LEUCINE; LIGAND; PHENYLALANINE; PROLINE; TRANSFORMING GROWTH FACTOR BETA; VALINE; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BETA SHEET; BIOSYNTHESIS; CHO CELL; CONFORMATION; CONTROLLED STUDY; DIMERIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HYDROPHOBICITY; IN VITRO STUDY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN SECRETION; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; CRICETULUS; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SECRETION; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; HYDROPHOBICITY; INHIBINS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; SEQUENCE ALIGNMENT; TRANSFORMING GROWTH FACTOR BETA;

EID: 66149084397     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808763200     Document Type: Article

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