Anti-inflammatory effect of insulin in the human hepatoma cell line HepG2 involves decreased transcription of IL-6 target genes and nuclear exclusion of FOXO1

Molecular and Cellular Biochemistry

Volumn 352, Issue 1-2, 2011, Pages 47-55

  Wallerstedt, Emelie ^a   Sandqvist, Madeléne ^a   Smith, Ulf ^a   Andersson, Christian X ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

FOXO1; HepG2; IL 6; Inflammation; Insulin; PKC

Indexed keywords

HAPTOGLOBIN; INSULIN; INTERLEUKIN 6; OROSOMUCOID; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE C DELTA; SERUM AMYLOID A; STAT3 PROTEIN; TRANSCRIPTION FACTOR FKHR;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN HEPG2; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL NUCLEUS; DNA PRIMERS; FORKHEAD TRANSCRIPTION FACTORS; GENE KNOCKDOWN TECHNIQUES; HUMANS; INFLAMMATION; INSULIN; INTERLEUKIN-6; LIVER NEOPLASMS; POLYMERASE CHAIN REACTION; PROTEIN KINASE C-DELTA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 79959236073     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0738-0     Document Type: Article

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