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Volumn 20, Issue 27, 2001, Pages 3464-3474
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The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway
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Author keywords
gp 130; IL 6; Ser phosphorylation; STAT3; Transcription; YXXQ motif
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Indexed keywords
1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE;
2 (2 AMINO 3 METHOXYPHENYL)CHROMONE;
CHIMERIC PROTEIN;
CYTOKINE;
EPIDERMAL GROWTH FACTOR;
GLYCOPROTEIN GP 130;
GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR;
GROWTH FACTOR;
INTERLEUKIN 6;
MITOGEN ACTIVATED PROTEIN KINASE;
PROTEIN KINASE C;
PROTEIN SERINE KINASE;
PROTEIN TYROSINE KINASE;
SERINE;
STAT3 PROTEIN;
STRESS ACTIVATED PROTEIN KINASE;
SYNAPTOPHYSIN;
TYROSINE;
ARTICLE;
CARBOXY TERMINAL SEQUENCE;
CHIMERA;
CONTROLLED STUDY;
CYTOPLASM;
GENE ACTIVATION;
GENETIC TRANSCRIPTION;
HUMAN;
HUMAN CELL;
PRIORITY JOURNAL;
PROTEIN MOTIF;
PROTEIN PHOSPHORYLATION;
SIGNAL TRANSDUCTION;
1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE;
3T3 CELLS;
ALANINE;
AMINO ACID SEQUENCE;
AMINO ACID SUBSTITUTION;
ANIMALS;
ANTIGENS, CD;
BINDING SITES;
CARCINOMA, HEPATOCELLULAR;
CELL LINE;
CYTOKINE RECEPTOR GP130;
DNA PRIMERS;
DNA-BINDING PROTEINS;
ENZYME INHIBITORS;
FLAVONOIDS;
GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT;
HUMANS;
INTERFERON-GAMMA, RECOMBINANT;
INTERLEUKIN-6;
LIVER NEOPLASMS;
MEMBRANE GLYCOPROTEINS;
MICE;
MITOGEN-ACTIVATED PROTEIN KINASES;
MOLECULAR SEQUENCE DATA;
MUTAGENESIS, SITE-DIRECTED;
PHOSPHORYLATION;
PROTEIN KINASES;
RECOMBINANT FUSION PROTEINS;
RECOMBINANT PROTEINS;
SERINE;
SIGNAL TRANSDUCTION;
STAT3 TRANSCRIPTION FACTOR;
TETRADECANOYLPHORBOL ACETATE;
TRANS-ACTIVATORS;
TRANSFECTION;
TUMOR CELLS, CULTURED;
TUMOR NECROSIS FACTOR-ALPHA;
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EID: 0035859010
PISSN: 09509232
EISSN: None
Source Type: Journal
DOI: 10.1038/sj.onc.1204461 Document Type: Article |
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Times cited : (59)
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References (55)
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