Alkynylation of N-(3-iodopyridin-2-yl)sulfonamide under Pd/C-Cu catalysis: A direct one pot synthesis of 7-azaindoles and their pharmacological evaluation as potential inhibitors of sirtuins

MedChemComm

Volumn 2, Issue 6, 2011, Pages 478-485

  Layek, Mohosin ^a,b   Syam Kumar, Y ^a   Islam, Aminul ^a   Karavarapu, Ravikumar ^c   Sengupta, Amrita ^c   Halder, Devyani ^c   Mukkanti, K ^b   Pal, Manojit ^c  

^a DR REDDY'S LABORATORIES LTD   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^c INSTITUTE OF LIFE SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

6 CHLORO 2,3,4,9 TETRAHYDRO 1H CARBAZOLE 1 CARBOXAMIDE; 7 AZAINDOLE DERIVATIVE; CARBON; COPPER; ENZYME INHIBITOR; EX 527; N (3 IODOPYRIDIN 2 YL)SULFONAMIDE; PALLADIUM; SEN 0014196; SIRTUIN; UNCLASSIFIED DRUG;

ALKYNYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CYCLIZATION; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HYDROGEN BOND; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 79959215879     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c1md00029b     Document Type: Article

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