Amurensin G, a potent natural SIRT1 inhibitor, rescues doxorubicin responsiveness via down-regulation of multidrug resistance 1

Molecular Pharmacology

Volumn 78, Issue 5, 2010, Pages 855-864

  Oh, Won Keun ^a   Cho, Kyoung Bin ^a   Hien, Tran Thi ^a   Kim, Tae Hyung ^b,c   Kim, Hyung Sik ^b   Dao, Trong Tuan ^a   Han, Hyo Kyung ^d   Kwon, Seong Min ^a   Ahn, Sang Gun ^a   Yoon, Jung Hoon ^a   Kim, Tae Hyun ^b,c   Kim, Yoon Gyoon ^c   Kang, Keon Wook ^a  

^a Chosun University   (South Korea)

^b Pusan National University   (South Korea)

^c Dankook University   (South Korea)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMURENSIN G; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN 1; PLANT EXTRACT; SILENT INFORMATION REGULATOR PROTEIN; SIRTUIN 1; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; FRACTIONATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MEDICINAL PLANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; DIBENZOCYCLOHEPTENES; DOWN-REGULATION; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; METHANOL; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; P-GLYCOPROTEIN; PLANT EXTRACTS; RESORCINOLS; SIRTUIN 1; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSPLANTATION, HETEROLOGOUS; VITIS;

EID: 77958126835     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.065961     Document Type: Article

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