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Volumn 80, Issue 3, 2011, Pages 411-432

Consensus on the utility of bone markers in the malignant bone disease setting

(14)  Coleman, Robert a   Costa, Luis b   Saad, Fred c   Cook, Richard d   Hadji, Peyman e   Terpos, Evangelos f   Garnero, Patrick g,h   Brown, Janet a,i   Body, Jean Jacques j   Smith, Matthew k   Lee, Ker Ai d   Major, Pierre l   Dimopoulos, Meletios f   Lipton, Allan m  

g INSERM   (France)

Author keywords

Antiresorptive; Bisphosphonate; Bone marker; Bone metastasis; Bone turnover; Cancer; Osteolysis

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALKALINE PHOSPHATASE; AMINO TERMINAL PROPEPTIDE OF PROCOLLAGEN TYPE 1; AMINO TERMINAL TELOPEPTIDE; BORTEZOMIB; CARBOXY TERMINAL PROPEPTIDE OF PROCOLLAGEN TYPE 1; CARBOXY TERMINAL TELOPEPTIDE; DENOSUMAB; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PAMIDRONIC ACID; PLACEBO; PROTEIN PRECURSOR; PYRIDINOLINE; TUMOR MARKER; UNCLASSIFIED DRUG; ZOLEDRONIC ACID;

EID: 79958775704     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2011.02.005     Document Type: Review
Times cited : (85)

References (188)
  • 1
    • 33750726077 scopus 로고    scopus 로고
    • Clinical features of metastatic bone disease and risk of skeletal morbidity
    • Coleman R.E. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 2006, 12:6243s-6249s.
    • (2006) Clin Cancer Res , vol.12
    • Coleman, R.E.1
  • 2
    • 48149106931 scopus 로고    scopus 로고
    • Distant disease-free interval, site of first relapse and post-relapse survival in BRCA1- and BRCA2-associated compared to sporadic breast cancer patients
    • Kriege M., Seynaeve C., Meijers-Heijboer H., et al. Distant disease-free interval, site of first relapse and post-relapse survival in BRCA1- and BRCA2-associated compared to sporadic breast cancer patients. Breast Cancer Res Treat 2008, 111:303-311.
    • (2008) Breast Cancer Res Treat , vol.111 , pp. 303-311
    • Kriege, M.1    Seynaeve, C.2    Meijers-Heijboer, H.3
  • 3
    • 33645834966 scopus 로고    scopus 로고
    • Metastatic patterns in adenocarcinoma
    • Hess K.R., Varadhachary G.R., Taylor S.H., et al. Metastatic patterns in adenocarcinoma. Cancer 2006, 106:1624-1633.
    • (2006) Cancer , vol.106 , pp. 1624-1633
    • Hess, K.R.1    Varadhachary, G.R.2    Taylor, S.H.3
  • 5
    • 33750738067 scopus 로고    scopus 로고
    • Basic mechanisms responsible for osteolytic and osteoblastic bone metastases
    • Guise T.A., Mohammad K.S., Clines G., et al. Basic mechanisms responsible for osteolytic and osteoblastic bone metastases. Clin Cancer Res 2006, 12:6213s-6216s.
    • (2006) Clin Cancer Res , vol.12
    • Guise, T.A.1    Mohammad, K.S.2    Clines, G.3
  • 6
    • 0032888683 scopus 로고    scopus 로고
    • Factors regulating the growth of metastatic cancer in bone
    • Boyce B.F., Yoneda T., Guise T.A. Factors regulating the growth of metastatic cancer in bone. Endocr Relat Cancer 1999, 6:333-347.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 333-347
    • Boyce, B.F.1    Yoneda, T.2    Guise, T.A.3
  • 8
    • 0034658725 scopus 로고    scopus 로고
    • Molecular mechanisms of osteolytic bone metastases
    • Guise T.A. Molecular mechanisms of osteolytic bone metastases. Cancer 2000, 88(Suppl.):2892-2898.
    • (2000) Cancer , vol.88 , Issue.SUPPL. , pp. 2892-2898
    • Guise, T.A.1
  • 10
    • 0344011473 scopus 로고    scopus 로고
    • Clinical review 165: markers of bone remodeling in metastatic bone disease
    • Fohr B., Dunstan C.R., Seibel M.J. Clinical review 165: markers of bone remodeling in metastatic bone disease. J Clin Endocrinol Metab 2003, 88:5059-5075.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5059-5075
    • Fohr, B.1    Dunstan, C.R.2    Seibel, M.J.3
  • 11
    • 27644471852 scopus 로고    scopus 로고
    • Clinical use of markers of bone turnover in metastatic bone disease
    • Seibel M.J. Clinical use of markers of bone turnover in metastatic bone disease. Nat Clin Pract Oncol 2005, 2:504-517.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 504-517
    • Seibel, M.J.1
  • 12
    • 36549088561 scopus 로고    scopus 로고
    • Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women
    • Goss P.E., Hadji P., Subar M., Abreu P., Thomsen T., Banke-Bochita J. Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women. Breast Cancer Res 2007, 9:R52.
    • (2007) Breast Cancer Res , vol.9
    • Goss, P.E.1    Hadji, P.2    Subar, M.3    Abreu, P.4    Thomsen, T.5    Banke-Bochita, J.6
  • 13
    • 1942470104 scopus 로고    scopus 로고
    • Contribution of androgen deprivation therapy to elevated osteoclast activity in men with metastatic prostate cancer
    • Michaelson M.D., Marujo R.M., Smith M.R. Contribution of androgen deprivation therapy to elevated osteoclast activity in men with metastatic prostate cancer. Clin Cancer Res 2004, 10:2705-2708.
    • (2004) Clin Cancer Res , vol.10 , pp. 2705-2708
    • Michaelson, M.D.1    Marujo, R.M.2    Smith, M.R.3
  • 14
    • 10744225319 scopus 로고    scopus 로고
    • The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation
    • Garnero P., Ferreras M., Karsdal M.A., et al. The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation. J Bone Miner Res 2003, 18:859-867.
    • (2003) J Bone Miner Res , vol.18 , pp. 859-867
    • Garnero, P.1    Ferreras, M.2    Karsdal, M.A.3
  • 15
    • 53649083433 scopus 로고    scopus 로고
    • Bone markers and their prognostic value in metastatic bone disease: clinical evidence and future directions
    • Coleman R., Brown J., Terpos E., et al. Bone markers and their prognostic value in metastatic bone disease: clinical evidence and future directions. Cancer Treat Rev 2008, 34:629-639.
    • (2008) Cancer Treat Rev , vol.34 , pp. 629-639
    • Coleman, R.1    Brown, J.2    Terpos, E.3
  • 16
    • 0034021345 scopus 로고    scopus 로고
    • Biochemical markers of bone metabolism reflect osteoclastic and osteoblastic activity in multiple myeloma
    • Abildgaard N., Glerup H., Rungby J., et al. Biochemical markers of bone metabolism reflect osteoclastic and osteoblastic activity in multiple myeloma. Eur J Haematol 2000, 64:121-129.
    • (2000) Eur J Haematol , vol.64 , pp. 121-129
    • Abildgaard, N.1    Glerup, H.2    Rungby, J.3
  • 17
    • 0037345794 scopus 로고    scopus 로고
    • Urinary N-telopeptide levels in multiple myeloma patients, correlation with Tc-99m-sestaMIBI scintigraphy and other biochemical markers of disease activity
    • Alexandrakis M.G., Kyriakou D.S., Passam F.H., Malliaraki N., Vlachonikolis I.G., Karkavitsas N. Urinary N-telopeptide levels in multiple myeloma patients, correlation with Tc-99m-sestaMIBI scintigraphy and other biochemical markers of disease activity. Hematol Oncol 2003, 21:17-24.
    • (2003) Hematol Oncol , vol.21 , pp. 17-24
    • Alexandrakis, M.G.1    Kyriakou, D.S.2    Passam, F.H.3    Malliaraki, N.4    Vlachonikolis, I.G.5    Karkavitsas, N.6
  • 18
    • 11144355547 scopus 로고    scopus 로고
    • Baseline serum NTx levels are prognostic in metastatic breast cancer patients with bone-only metastasis
    • Ali S.M., Demers L.M., Leitzel K., et al. Baseline serum NTx levels are prognostic in metastatic breast cancer patients with bone-only metastasis. Ann Oncol 2004, 15:455-459.
    • (2004) Ann Oncol , vol.15 , pp. 455-459
    • Ali, S.M.1    Demers, L.M.2    Leitzel, K.3
  • 19
    • 0030821404 scopus 로고    scopus 로고
    • Usefulness of bone metabolic markers in the diagnosis and follow-up of bone metastasis from lung cancer
    • Aruga A., Koizumi M., Hotta R., Takahashi S., Ogata E. Usefulness of bone metabolic markers in the diagnosis and follow-up of bone metastasis from lung cancer. Br J Cancer 1997, 76:760-764.
    • (1997) Br J Cancer , vol.76 , pp. 760-764
    • Aruga, A.1    Koizumi, M.2    Hotta, R.3    Takahashi, S.4    Ogata, E.5
  • 21
    • 0036822229 scopus 로고    scopus 로고
    • Metabolic effects of single-dose pamidronate administration in prostate cancer patients with bone metastases
    • Berruti A., Dogliotti L., Tucci M., et al. Metabolic effects of single-dose pamidronate administration in prostate cancer patients with bone metastases. Int J Biol Markers 2002, 17:244-252.
    • (2002) Int J Biol Markers , vol.17 , pp. 244-252
    • Berruti, A.1    Dogliotti, L.2    Tucci, M.3
  • 22
    • 0030036375 scopus 로고    scopus 로고
    • Biochemical evaluation of bone turnover in cancer patients with bone metastases: relationship with radiograph appearances and disease extension
    • Berruti A., Piovesan A., Torta M., et al. Biochemical evaluation of bone turnover in cancer patients with bone metastases: relationship with radiograph appearances and disease extension. Br J Cancer 1996, 73:1581-1587.
    • (1996) Br J Cancer , vol.73 , pp. 1581-1587
    • Berruti, A.1    Piovesan, A.2    Torta, M.3
  • 23
    • 0029549082 scopus 로고
    • Biochemical picture of bone metabolism in breast cancer patients with bone metastases
    • Berruti A., Torta M., Piovesan A., et al. Biochemical picture of bone metabolism in breast cancer patients with bone metastases. Anticancer Res 1995, 15:2871-2875.
    • (1995) Anticancer Res , vol.15 , pp. 2871-2875
    • Berruti, A.1    Torta, M.2    Piovesan, A.3
  • 24
    • 0036817328 scopus 로고    scopus 로고
    • Assessment of the effects of breast cancer on bone and the response to therapy
    • Brown J.E., Coleman R.E. Assessment of the effects of breast cancer on bone and the response to therapy. Breast 2002, 11:375-385.
    • (2002) Breast , vol.11 , pp. 375-385
    • Brown, J.E.1    Coleman, R.E.2
  • 26
    • 33645506827 scopus 로고    scopus 로고
    • Tartrate-resistant acid phosphatase 5b activity is a useful bone marker for monitoring bone metastases in breast cancer patients after treatment
    • Chung Y.C., Ku C.H., Chao T.Y., Yu J.C., Chen M.M., Lee S.H. Tartrate-resistant acid phosphatase 5b activity is a useful bone marker for monitoring bone metastases in breast cancer patients after treatment. Cancer Epidemiol Biomarkers Prev 2006, 15:424-428.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 424-428
    • Chung, Y.C.1    Ku, C.H.2    Chao, T.Y.3    Yu, J.C.4    Chen, M.M.5    Lee, S.H.6
  • 27
    • 0034659963 scopus 로고    scopus 로고
    • Biochemical markers and skeletal metastases
    • Demers L.M., Costa L., Lipton A. Biochemical markers and skeletal metastases. Cancer 2000, 88(Suppl.):2919-2926.
    • (2000) Cancer , vol.88 , Issue.SUPPL. , pp. 2919-2926
    • Demers, L.M.1    Costa, L.2    Lipton, A.3
  • 29
    • 0031773841 scopus 로고    scopus 로고
    • Diagnostic and prognostic value of biochemical markers in malignant bone disease: a prospective study on the effect of bisphosphonate on pain intensity and progression of malignant bone disease
    • Engler H., Koeberle D., Thuerlimann B., Senn H.J., Riesen W.F. Diagnostic and prognostic value of biochemical markers in malignant bone disease: a prospective study on the effect of bisphosphonate on pain intensity and progression of malignant bone disease. Clin Chem Lab Med 1998, 36:879-885.
    • (1998) Clin Chem Lab Med , vol.36 , pp. 879-885
    • Engler, H.1    Koeberle, D.2    Thuerlimann, B.3    Senn, H.J.4    Riesen, W.F.5
  • 30
    • 0033023582 scopus 로고    scopus 로고
    • Diagnostic value of urinary N-telopeptide of type I collagen in prostate cancer: comparison with bone scintigraphy
    • Fukumitsu N., Uchiyama M., Mori Y., et al. Diagnostic value of urinary N-telopeptide of type I collagen in prostate cancer: comparison with bone scintigraphy. Kaku Igaku 1999, 36:333-339.
    • (1999) Kaku Igaku , vol.36 , pp. 333-339
    • Fukumitsu, N.1    Uchiyama, M.2    Mori, Y.3
  • 31
    • 33646237342 scopus 로고    scopus 로고
    • Bone markers and current laboratory assays
    • Hannon R.A., Eastell R. Bone markers and current laboratory assays. Cancer Treat Rev 2006, 32(Suppl. 1):7-14.
    • (2006) Cancer Treat Rev , vol.32 , Issue.SUPPL. 1 , pp. 7-14
    • Hannon, R.A.1    Eastell, R.2
  • 32
    • 33846213230 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover in patients with localized and metastasized prostate cancer
    • Hegele A., Wahl H.G., Varga Z., et al. Biochemical markers of bone turnover in patients with localized and metastasized prostate cancer. BJU Int 2007, 99:330-334.
    • (2007) BJU Int , vol.99 , pp. 330-334
    • Hegele, A.1    Wahl, H.G.2    Varga, Z.3
  • 33
    • 33748102833 scopus 로고    scopus 로고
    • Diagnostic and prognostic validity of serum bone turnover markers in metastatic renal cell carcinoma
    • Jung K., Lein M., Ringsdorf M., et al. Diagnostic and prognostic validity of serum bone turnover markers in metastatic renal cell carcinoma. J Urol 2006, 176:1326-1331.
    • (2006) J Urol , vol.176 , pp. 1326-1331
    • Jung, K.1    Lein, M.2    Ringsdorf, M.3
  • 34
    • 4043064387 scopus 로고    scopus 로고
    • Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: diagnostic and prognostic implications
    • Jung K., Lein M., Stephan C., et al. Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: diagnostic and prognostic implications. Int J Cancer 2004, 111:783-791.
    • (2004) Int J Cancer , vol.111 , pp. 783-791
    • Jung, K.1    Lein, M.2    Stephan, C.3
  • 35
    • 1342306706 scopus 로고    scopus 로고
    • Determination and biological relevance of serum cross-linked type I collagen N-telopeptide and bone-specific alkaline phosphatase in breast metastatic cancer
    • Kanakis I., Nikolaou M., Pectasides D., Kiamouris C., Karamanos N.K. Determination and biological relevance of serum cross-linked type I collagen N-telopeptide and bone-specific alkaline phosphatase in breast metastatic cancer. J Pharm Biomed Anal 2004, 34:827-832.
    • (2004) J Pharm Biomed Anal , vol.34 , pp. 827-832
    • Kanakis, I.1    Nikolaou, M.2    Pectasides, D.3    Kiamouris, C.4    Karamanos, N.K.5
  • 36
    • 0036582570 scopus 로고    scopus 로고
    • Cross-linked collagen C- and N-telopeptides for an early diagnosis of bone metastasis from breast cancer
    • Kiuchi K., Ishikawa T., Hamaguchi Y., et al. Cross-linked collagen C- and N-telopeptides for an early diagnosis of bone metastasis from breast cancer. Oncol Rep 2002, 9:595-598.
    • (2002) Oncol Rep , vol.9 , pp. 595-598
    • Kiuchi, K.1    Ishikawa, T.2    Hamaguchi, Y.3
  • 37
    • 0344872699 scopus 로고    scopus 로고
    • Comparison of serum bone resorption markers in the diagnosis of skeletal metastasis
    • Koizumi M., Takahashi S., Ogata E. Comparison of serum bone resorption markers in the diagnosis of skeletal metastasis. Anticancer Res 2003, 23:4095-4099.
    • (2003) Anticancer Res , vol.23 , pp. 4095-4099
    • Koizumi, M.1    Takahashi, S.2    Ogata, E.3
  • 38
    • 0041308329 scopus 로고    scopus 로고
    • Bone metabolic markers in bisphosphonate therapy for skeletal metastases in patients with breast cancer
    • Koizumi M., Takahashi S., Ogata E. Bone metabolic markers in bisphosphonate therapy for skeletal metastases in patients with breast cancer. Breast Cancer 2003, 10:21-27.
    • (2003) Breast Cancer , vol.10 , pp. 21-27
    • Koizumi, M.1    Takahashi, S.2    Ogata, E.3
  • 39
    • 0035071433 scopus 로고    scopus 로고
    • The serum level of the amino-terminal propeptide of type I procollagen is a sensitive marker for prostate cancer metastasis to bone
    • Koizumi M., Yonese J., Fukui I., Ogata E. The serum level of the amino-terminal propeptide of type I procollagen is a sensitive marker for prostate cancer metastasis to bone. BJU Int 2001, 87:348-351.
    • (2001) BJU Int , vol.87 , pp. 348-351
    • Koizumi, M.1    Yonese, J.2    Fukui, I.3    Ogata, E.4
  • 40
    • 34547659662 scopus 로고    scopus 로고
    • Serum bone turnover markers (PINP and ICTP) for the early detection of bone metastases in patients with prostate cancer: a longitudinal approach
    • discussion follows
    • Koopmans N., de Jong I.J., Breeuwsma A.J., van der Veer E. Serum bone turnover markers (PINP and ICTP) for the early detection of bone metastases in patients with prostate cancer: a longitudinal approach. J Urol 2007, 178:849-853. discussion follows.
    • (2007) J Urol , vol.178 , pp. 849-853
    • Koopmans, N.1    de Jong, I.J.2    Breeuwsma, A.J.3    van der Veer, E.4
  • 41
    • 33645457788 scopus 로고    scopus 로고
    • The relative use of eight collagenous and noncollagenous markers for diagnosis of skeletal metastases in breast, prostate, or lung cancer patients
    • Leeming D.J., Koizumi M., Byrjalsen I., Li B., Qvist P., Tanko L.B. The relative use of eight collagenous and noncollagenous markers for diagnosis of skeletal metastases in breast, prostate, or lung cancer patients. Cancer Epidemiol Biomarkers Prev 2006, 15:32-38.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 32-38
    • Leeming, D.J.1    Koizumi, M.2    Byrjalsen, I.3    Li, B.4    Qvist, P.5    Tanko, L.B.6
  • 42
    • 34248143552 scopus 로고    scopus 로고
    • Clinical utility of biochemical markers of bone metabolism for improving the management of patients with advanced multiple myeloma
    • Lipton A., Cook R.J., Coleman R.E., et al. Clinical utility of biochemical markers of bone metabolism for improving the management of patients with advanced multiple myeloma. Clin Lymphoma Myeloma 2007, 7:346-353.
    • (2007) Clin Lymphoma Myeloma , vol.7 , pp. 346-353
    • Lipton, A.1    Cook, R.J.2    Coleman, R.E.3
  • 43
    • 0035003870 scopus 로고    scopus 로고
    • Bone markers in the management of metastatic bone disease
    • Lipton A., Costa L., Ali S.M., Demers L.M. Bone markers in the management of metastatic bone disease. Cancer Treat Rev 2001, 27:181-185.
    • (2001) Cancer Treat Rev , vol.27 , pp. 181-185
    • Lipton, A.1    Costa, L.2    Ali, S.M.3    Demers, L.M.4
  • 44
    • 17044446655 scopus 로고    scopus 로고
    • Markers of bone resorption in patients treated with pamidronate
    • Lipton A., Demers L., Curley E., et al. Markers of bone resorption in patients treated with pamidronate. Eur J Cancer 1998, 34:2021-2026.
    • (1998) Eur J Cancer , vol.34 , pp. 2021-2026
    • Lipton, A.1    Demers, L.2    Curley, E.3
  • 45
    • 8444230056 scopus 로고    scopus 로고
    • Tartrate-resistant acid phosphatase as a marker of bone metastases in patients with breast cancer and prostate cancer
    • Lyubimova N.V., Pashkov M.V., Tyulyandin S.A., Gol'dberg V.E., Kushlinskii N.E. Tartrate-resistant acid phosphatase as a marker of bone metastases in patients with breast cancer and prostate cancer. Bull Exp Biol Med 2004, 138:77-79.
    • (2004) Bull Exp Biol Med , vol.138 , pp. 77-79
    • Lyubimova, N.V.1    Pashkov, M.V.2    Tyulyandin, S.A.3    Gol'dberg, V.E.4    Kushlinskii, N.E.5
  • 46
    • 0031690523 scopus 로고    scopus 로고
    • Utility of biochemical markers of bone turnover in the follow-up of patients treated with bisphosphonates
    • Rosen H.N., Moses A.C., Garber J., Ross D.S., Lee S.L., Greenspan S.L. Utility of biochemical markers of bone turnover in the follow-up of patients treated with bisphosphonates. Calcif Tissue Int 1998, 63:363-368.
    • (1998) Calcif Tissue Int , vol.63 , pp. 363-368
    • Rosen, H.N.1    Moses, A.C.2    Garber, J.3    Ross, D.S.4    Lee, S.L.5    Greenspan, S.L.6
  • 47
    • 10244252871 scopus 로고    scopus 로고
    • Prognostic value of urinary pyridinium crosslinks and their derivatives in multiple myeloma
    • Samani K.K., Brazier M., Mathiot C., et al. Prognostic value of urinary pyridinium crosslinks and their derivatives in multiple myeloma. Ann Hematol 2005, 84:19-24.
    • (2005) Ann Hematol , vol.84 , pp. 19-24
    • Samani, K.K.1    Brazier, M.2    Mathiot, C.3
  • 48
    • 33845193025 scopus 로고    scopus 로고
    • Myeloma bone disease: pathogenetic mechanisms and clinical assessment
    • Silvestris F., Lombardi L., De Matteo M., Bruno A., Dammacco F. Myeloma bone disease: pathogenetic mechanisms and clinical assessment. Leuk Res 2007, 31:129-138.
    • (2007) Leuk Res , vol.31 , pp. 129-138
    • Silvestris, F.1    Lombardi, L.2    De Matteo, M.3    Bruno, A.4    Dammacco, F.5
  • 49
    • 0035162090 scopus 로고    scopus 로고
    • Biochemical markers for the detection of bone metastasis in patients with prostate cancer: diagnostic efficacy and the effect of hormonal therapy
    • Tamada T., Sone T., Tomomitsu T., Jo Y., Tanaka H., Fukunaga M. Biochemical markers for the detection of bone metastasis in patients with prostate cancer: diagnostic efficacy and the effect of hormonal therapy. J Bone Miner Metab 2001, 19:45-51.
    • (2001) J Bone Miner Metab , vol.19 , pp. 45-51
    • Tamada, T.1    Sone, T.2    Tomomitsu, T.3    Jo, Y.4    Tanaka, H.5    Fukunaga, M.6
  • 50
    • 33646239372 scopus 로고    scopus 로고
    • Biochemical markers of bone metabolism in multiple myeloma
    • Terpos E. Biochemical markers of bone metabolism in multiple myeloma. Cancer Treat Rev 2006, 32(Suppl. 1):15-19.
    • (2006) Cancer Treat Rev , vol.32 , Issue.SUPPL. 1 , pp. 15-19
    • Terpos, E.1
  • 51
    • 14644420230 scopus 로고    scopus 로고
    • The role of markers of bone remodeling in multiple myeloma
    • Terpos E., Politou M., Rahemtulla A. The role of markers of bone remodeling in multiple myeloma. Blood Rev 2005, 19:125-142.
    • (2005) Blood Rev , vol.19 , pp. 125-142
    • Terpos, E.1    Politou, M.2    Rahemtulla, A.3
  • 52
    • 0035139249 scopus 로고    scopus 로고
    • Cross-linked type I collagen C- and N-telopeptides in women with bone metastases from breast cancer
    • Ulrich U., Rhiem K., Schmolling J., et al. Cross-linked type I collagen C- and N-telopeptides in women with bone metastases from breast cancer. Arch Gynecol Obstet 2001, 264:186-190.
    • (2001) Arch Gynecol Obstet , vol.264 , pp. 186-190
    • Ulrich, U.1    Rhiem, K.2    Schmolling, J.3
  • 53
    • 0031032567 scopus 로고    scopus 로고
    • Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy
    • Vinholes J., Guo C.Y., Purohit O.P., Eastell R., Coleman R.E. Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy. J Clin Oncol 1997, 15:131-138.
    • (1997) J Clin Oncol , vol.15 , pp. 131-138
    • Vinholes, J.1    Guo, C.Y.2    Purohit, O.P.3    Eastell, R.4    Coleman, R.E.5
  • 54
    • 33747181617 scopus 로고    scopus 로고
    • Association of 12 serum biochemical markers of angiogenesis, tumour invasion and bone turnover with bone metastases from breast cancer: a crossectional and longitudinal evaluation
    • Voorzanger-Rousselot N., Juillet F., Mareau E., Zimmermann J., Kalebic T., Garnero P. Association of 12 serum biochemical markers of angiogenesis, tumour invasion and bone turnover with bone metastases from breast cancer: a crossectional and longitudinal evaluation. Br J Cancer 2006, 95:506-514.
    • (2006) Br J Cancer , vol.95 , pp. 506-514
    • Voorzanger-Rousselot, N.1    Juillet, F.2    Mareau, E.3    Zimmermann, J.4    Kalebic, T.5    Garnero, P.6
  • 55
    • 33746338874 scopus 로고    scopus 로고
    • Bone markers in multiple myeloma
    • Heider U., Fleissner C., Zavrski I., et al. Bone markers in multiple myeloma. Eur J Cancer 2006, 42:1544-1553.
    • (2006) Eur J Cancer , vol.42 , pp. 1544-1553
    • Heider, U.1    Fleissner, C.2    Zavrski, I.3
  • 56
    • 12344273384 scopus 로고    scopus 로고
    • Diagnostic value of bone remodeling markers in the diagnosis of bone metastases in patients with breast cancer
    • Pectasides D., Farmakis D., Nikolaou M., et al. Diagnostic value of bone remodeling markers in the diagnosis of bone metastases in patients with breast cancer. J Pharm Biomed Anal 2005, 37:171-176.
    • (2005) J Pharm Biomed Anal , vol.37 , pp. 171-176
    • Pectasides, D.1    Farmakis, D.2    Nikolaou, M.3
  • 57
    • 33750695333 scopus 로고    scopus 로고
    • Serum alkaline phosphatase isoenzyme activities in canine malignant mammary neoplasms with and without osseous transformation
    • Karayannopoulou M., Polizopoulou Z.S., Koutinas A.F., et al. Serum alkaline phosphatase isoenzyme activities in canine malignant mammary neoplasms with and without osseous transformation. Vet Clin Pathol 2006, 35:287-290.
    • (2006) Vet Clin Pathol , vol.35 , pp. 287-290
    • Karayannopoulou, M.1    Polizopoulou, Z.S.2    Koutinas, A.F.3
  • 58
    • 0035871392 scopus 로고    scopus 로고
    • Diagnostic value of bone-turnover metabolites in the diagnosis of bone metastases in patients with lung carcinoma
    • Izumi M., Nakanishi Y., Takayama K., et al. Diagnostic value of bone-turnover metabolites in the diagnosis of bone metastases in patients with lung carcinoma. Cancer 2001, 91:1487-1493.
    • (2001) Cancer , vol.91 , pp. 1487-1493
    • Izumi, M.1    Nakanishi, Y.2    Takayama, K.3
  • 59
    • 33846103893 scopus 로고    scopus 로고
    • Biochemical approach to the detection and monitoring of metastatic bone disease: what do we know and what questions need answers?
    • Tanko L.B., Karsdal M.A., Christiansen C., Leeming D.J. Biochemical approach to the detection and monitoring of metastatic bone disease: what do we know and what questions need answers?. Cancer Metastasis Rev 2006, 25:659-668.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 659-668
    • Tanko, L.B.1    Karsdal, M.A.2    Christiansen, C.3    Leeming, D.J.4
  • 61
    • 27744433493 scopus 로고    scopus 로고
    • Usefulness of bone formation markers in breast cancer
    • Palma M.A., Body J.J. Usefulness of bone formation markers in breast cancer. Int J Biol Markers 2005, 20:146-155.
    • (2005) Int J Biol Markers , vol.20 , pp. 146-155
    • Palma, M.A.1    Body, J.J.2
  • 62
    • 5444262558 scopus 로고    scopus 로고
    • Bisphosphonates: clinical experience
    • Coleman R.E. Bisphosphonates: clinical experience. Oncologist 2004, 9(Suppl. 4):14-27.
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 4 , pp. 14-27
    • Coleman, R.E.1
  • 63
    • 0038166881 scopus 로고    scopus 로고
    • Tartrate-resistant acid phosphatase isoform 5b: a novel serum marker for monitoring bone disease in multiple myeloma
    • Terpos E., de la Fuente J., Szydlo R., et al. Tartrate-resistant acid phosphatase isoform 5b: a novel serum marker for monitoring bone disease in multiple myeloma. Int J Cancer 2003, 106:455-457.
    • (2003) Int J Cancer , vol.106 , pp. 455-457
    • Terpos, E.1    de la Fuente, J.2    Szydlo, R.3
  • 64
    • 34548016567 scopus 로고    scopus 로고
    • Short-term effects of pamidronate on bone turnover: can bone markers be considered predictive of the analgesic response?
    • Martinetti A., Ripamonti C., Miceli R., et al. Short-term effects of pamidronate on bone turnover: can bone markers be considered predictive of the analgesic response?. Oncol Rep 2007, 17:1533-1540.
    • (2007) Oncol Rep , vol.17 , pp. 1533-1540
    • Martinetti, A.1    Ripamonti, C.2    Miceli, R.3
  • 65
    • 0032851189 scopus 로고    scopus 로고
    • Differential patterns of bone turnover in relation to bone pain and disease extent in bone in cancer patients with skeletal metastases
    • Berruti A., Dogliotti L., Gorzegno G., et al. Differential patterns of bone turnover in relation to bone pain and disease extent in bone in cancer patients with skeletal metastases. Clin Chem 1999, 45:1240-1247.
    • (1999) Clin Chem , vol.45 , pp. 1240-1247
    • Berruti, A.1    Dogliotti, L.2    Gorzegno, G.3
  • 66
    • 23944448283 scopus 로고    scopus 로고
    • Clinicopathological correlation between expression of PTHrP receptor and various prognostic factors in breast cancer without axillary lymph node metastasis
    • Suzuki Y., Tokuda Y., Saito Y., Umemura S., Osamura R.Y. Clinicopathological correlation between expression of PTHrP receptor and various prognostic factors in breast cancer without axillary lymph node metastasis. Tokai J Exp Clin Med 2005, 30:127-132.
    • (2005) Tokai J Exp Clin Med , vol.30 , pp. 127-132
    • Suzuki, Y.1    Tokuda, Y.2    Saito, Y.3    Umemura, S.4    Osamura, R.Y.5
  • 67
    • 2442432700 scopus 로고    scopus 로고
    • Serum bone markers in breast cancer patients during 5-fluorouracil, epirubicin and cyclophosphamide (FEC) therapy
    • Kailajarvi M.E., Salminen E.K., Paija O.M., Virtanent A.M., Leino A.E., Irjala K.A. Serum bone markers in breast cancer patients during 5-fluorouracil, epirubicin and cyclophosphamide (FEC) therapy. Anticancer Res 2004, 24:1271-1274.
    • (2004) Anticancer Res , vol.24 , pp. 1271-1274
    • Kailajarvi, M.E.1    Salminen, E.K.2    Paija, O.M.3    Virtanent, A.M.4    Leino, A.E.5    Irjala, K.A.6
  • 68
    • 1642397685 scopus 로고    scopus 로고
    • Relationship between pretreatment bone resorption and vertebral fracture incidence in postmenopausal osteoporotic women treated with risedronate
    • Seibel M.J., Naganathan V., Barton I., Grauer A. Relationship between pretreatment bone resorption and vertebral fracture incidence in postmenopausal osteoporotic women treated with risedronate. J Bone Miner Res 2004, 19:323-329.
    • (2004) J Bone Miner Res , vol.19 , pp. 323-329
    • Seibel, M.J.1    Naganathan, V.2    Barton, I.3    Grauer, A.4
  • 69
    • 0036316435 scopus 로고    scopus 로고
    • Relationship of bone turnover parameters, endogenous hormones and vit D deficiency to hip fracture in elderly postmenopausal women
    • Erem C., Tanakol R., Alagol F., Omer B., Cetin O. Relationship of bone turnover parameters, endogenous hormones and vit D deficiency to hip fracture in elderly postmenopausal women. Int J Clin Pract 2002, 56:333-337.
    • (2002) Int J Clin Pract , vol.56 , pp. 333-337
    • Erem, C.1    Tanakol, R.2    Alagol, F.3    Omer, B.4    Cetin, O.5
  • 70
    • 33646045900 scopus 로고    scopus 로고
    • Short-term changes in bone turnover markers and bone mineral density response to parathyroid hormone in postmenopausal women with osteoporosis
    • Bauer D.C., Garnero P., Bilezikian J.P., et al. Short-term changes in bone turnover markers and bone mineral density response to parathyroid hormone in postmenopausal women with osteoporosis. J Clin Endocrinol Metab 2006, 91:1370-1375.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1370-1375
    • Bauer, D.C.1    Garnero, P.2    Bilezikian, J.P.3
  • 71
    • 4644330090 scopus 로고    scopus 로고
    • Determinants of one-year response of lumbar bone mineral density to alendronate treatment in elderly Japanese women with osteoporosis
    • Iwamoto J., Takeda T., Sato Y., Uzawa M. Determinants of one-year response of lumbar bone mineral density to alendronate treatment in elderly Japanese women with osteoporosis. Yonsei Med J 2004, 45:676-682.
    • (2004) Yonsei Med J , vol.45 , pp. 676-682
    • Iwamoto, J.1    Takeda, T.2    Sato, Y.3    Uzawa, M.4
  • 72
    • 4544299323 scopus 로고    scopus 로고
    • Effect of walking exercise on bone metabolism in postmenopausal women with osteopenia/osteoporosis
    • Yamazaki S., Ichimura S., Iwamoto J., Takeda T., Toyama Y. Effect of walking exercise on bone metabolism in postmenopausal women with osteopenia/osteoporosis. J Bone Miner Metab 2004, 22:500-508.
    • (2004) J Bone Miner Metab , vol.22 , pp. 500-508
    • Yamazaki, S.1    Ichimura, S.2    Iwamoto, J.3    Takeda, T.4    Toyama, Y.5
  • 73
    • 0043125769 scopus 로고    scopus 로고
    • Biochemical markers for prediction of 4-year response in bone mass during bisphosphonate treatment for prevention of postmenopausal osteoporosis
    • Ravn P., Thompson D.E., Ross P.D., Christiansen C. Biochemical markers for prediction of 4-year response in bone mass during bisphosphonate treatment for prevention of postmenopausal osteoporosis. Bone 2003, 33:150-158.
    • (2003) Bone , vol.33 , pp. 150-158
    • Ravn, P.1    Thompson, D.E.2    Ross, P.D.3    Christiansen, C.4
  • 74
    • 57649200194 scopus 로고    scopus 로고
    • Evidence-based guidelines for the use of biochemical markers of bone turnover in the selection and monitoring of bisphosphonate treatment in osteoporosis: a consensus document of the Belgian Bone Club
    • Bergmann P., Body J.J., Boonen S., et al. Evidence-based guidelines for the use of biochemical markers of bone turnover in the selection and monitoring of bisphosphonate treatment in osteoporosis: a consensus document of the Belgian Bone Club. Int J Clin Pract 2009, 63:19-26.
    • (2009) Int J Clin Pract , vol.63 , pp. 19-26
    • Bergmann, P.1    Body, J.J.2    Boonen, S.3
  • 75
    • 34248678476 scopus 로고    scopus 로고
    • Biochemical markers in oncology. Part I: molecular basis. Part II: clinical uses
    • Voorzanger-Rousselot N., Garnero P. Biochemical markers in oncology. Part I: molecular basis. Part II: clinical uses. Cancer Treat Rev 2007, 33:230-283.
    • (2007) Cancer Treat Rev , vol.33 , pp. 230-283
    • Voorzanger-Rousselot, N.1    Garnero, P.2
  • 76
    • 33744992723 scopus 로고    scopus 로고
    • Possible predictive markers related to micro-metastasis in breast cancer patients
    • Zhu L., Loo W.T., Cheng C.W., Chow L.W. Possible predictive markers related to micro-metastasis in breast cancer patients. Oncol Rep 2006, 15:1217-1223.
    • (2006) Oncol Rep , vol.15 , pp. 1217-1223
    • Zhu, L.1    Loo, W.T.2    Cheng, C.W.3    Chow, L.W.4
  • 78
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukemia-advances in biology and new approaches to treatment
    • Goldman J.M., Melo J.V. Chronic myeloid leukemia-advances in biology and new approaches to treatment. N Engl J Med 2003, 349:1451-1464.
    • (2003) N Engl J Med , vol.349 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 79
    • 0035003725 scopus 로고    scopus 로고
    • PSA doubling time as a predictor of clinical progression after biochemical failure following radical prostatectomy for prostate cancer
    • Roberts S.G., Blute M.L., Bergstralh E.J., Slezak J.M., Zincke H. PSA doubling time as a predictor of clinical progression after biochemical failure following radical prostatectomy for prostate cancer. Mayo Clin Proc 2001, 76:576-581.
    • (2001) Mayo Clin Proc , vol.76 , pp. 576-581
    • Roberts, S.G.1    Blute, M.L.2    Bergstralh, E.J.3    Slezak, J.M.4    Zincke, H.5
  • 81
    • 43249126494 scopus 로고    scopus 로고
    • Factors associated with outcome in patients with advanced renal cell carcinoma in the era of antiangiogenic agents
    • Choueiri T.K. Factors associated with outcome in patients with advanced renal cell carcinoma in the era of antiangiogenic agents. Clin Genitourin Cancer 2008, 6:15-20.
    • (2008) Clin Genitourin Cancer , vol.6 , pp. 15-20
    • Choueiri, T.K.1
  • 82
    • 54049130127 scopus 로고    scopus 로고
    • VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab
    • Moehler M., Frings C., Mueller A., et al. VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab. World J Gastroenterol 2008, 14:4156-4167.
    • (2008) World J Gastroenterol , vol.14 , pp. 4156-4167
    • Moehler, M.1    Frings, C.2    Mueller, A.3
  • 83
    • 21144438189 scopus 로고    scopus 로고
    • Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer
    • Smith M.R., Kabbinavar F., Saad F., et al. Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer. J Clin Oncol 2005, 23:2918-2925.
    • (2005) J Clin Oncol , vol.23 , pp. 2918-2925
    • Smith, M.R.1    Kabbinavar, F.2    Saad, F.3
  • 84
    • 0036468002 scopus 로고    scopus 로고
    • Prospective evaluation of the peptide-bound collagen type I cross-links N-telopeptide and C-telopeptide in predicting bone metastases status
    • Costa L., Demers L.M., Gouveia-Oliveira A., et al. Prospective evaluation of the peptide-bound collagen type I cross-links N-telopeptide and C-telopeptide in predicting bone metastases status. J Clin Oncol 2002, 20:850-856.
    • (2002) J Clin Oncol , vol.20 , pp. 850-856
    • Costa, L.1    Demers, L.M.2    Gouveia-Oliveira, A.3
  • 85
    • 80655147629 scopus 로고    scopus 로고
    • Meta-analysis of effects of zoledronic acid on survival in patients with metastatic bone disease (MBD) and high bone turnover
    • [abstract P81]
    • Coleman R., Cook R., Saad F., et al. Meta-analysis of effects of zoledronic acid on survival in patients with metastatic bone disease (MBD) and high bone turnover. Cancer Treat Rev 2008, 34(Suppl.):S86. [abstract P81].
    • (2008) Cancer Treat Rev , vol.34 , Issue.SUPPL.
    • Coleman, R.1    Cook, R.2    Saad, F.3
  • 86
    • 19944432878 scopus 로고    scopus 로고
    • Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors
    • Brown J.E., Cook R.J., Major P., et al. Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors. J Natl Cancer Inst 2005, 97:59-69.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 59-69
    • Brown, J.E.1    Cook, R.J.2    Major, P.3
  • 87
    • 24644479228 scopus 로고    scopus 로고
    • Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid
    • Coleman R.E., Major P., Lipton A., et al. Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid. J Clin Oncol 2005, 23:4925-4935.
    • (2005) J Clin Oncol , vol.23 , pp. 4925-4935
    • Coleman, R.E.1    Major, P.2    Lipton, A.3
  • 88
    • 35548960086 scopus 로고    scopus 로고
    • Zoledronic acid and survival in breast cancer patients with bone metastases and elevated markers of osteoclast activity
    • Lipton A., Cook R.J., Major P., Smith M.R., Coleman R.E. Zoledronic acid and survival in breast cancer patients with bone metastases and elevated markers of osteoclast activity. Oncologist 2007, 12:1035-1043.
    • (2007) Oncologist , vol.12 , pp. 1035-1043
    • Lipton, A.1    Cook, R.J.2    Major, P.3    Smith, M.R.4    Coleman, R.E.5
  • 89
    • 47149118386 scopus 로고    scopus 로고
    • Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid
    • Lipton A., Cook R., Saad F., et al. Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid. Cancer 2008, 113:193-201.
    • (2008) Cancer , vol.113 , pp. 193-201
    • Lipton, A.1    Cook, R.2    Saad, F.3
  • 90
    • 0033962103 scopus 로고    scopus 로고
    • Markers of bone turnover for the management of patients with bone metastases from prostate cancer
    • Garnero P., Buchs N., Zekri J., Rizzoli R., Coleman R.E., Delmas P.D. Markers of bone turnover for the management of patients with bone metastases from prostate cancer. Br J Cancer 2000, 82:858-864.
    • (2000) Br J Cancer , vol.82 , pp. 858-864
    • Garnero, P.1    Buchs, N.2    Zekri, J.3    Rizzoli, R.4    Coleman, R.E.5    Delmas, P.D.6
  • 91
    • 60549099966 scopus 로고    scopus 로고
    • Use of elevated bone turnover to predict bone metastasis
    • [abstract 591]
    • Lipton A., Chapman J.W., Demers L., et al. Use of elevated bone turnover to predict bone metastasis. J Clin Oncol 2008, 26(Suppl.):28s. [abstract 591].
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Lipton, A.1    Chapman, J.W.2    Demers, L.3
  • 92
    • 0033175309 scopus 로고    scopus 로고
    • Biochemical markers for assessment of bone metastases in patients with breast cancer
    • Hou M.F., Tsai L.Y., Tsai S.M., et al. Biochemical markers for assessment of bone metastases in patients with breast cancer. Kaohsiung J Med Sci 1999, 15:452-460.
    • (1999) Kaohsiung J Med Sci , vol.15 , pp. 452-460
    • Hou, M.F.1    Tsai, L.Y.2    Tsai, S.M.3
  • 93
    • 0018402579 scopus 로고
    • Urinary hydroxyproline in healthy patients and in prostate patients with and without bone metastases
    • Heller W., Harzmann R., Bichler K.H., Schmidt K. Urinary hydroxyproline in healthy patients and in prostate patients with and without bone metastases. Curr Probl Clin Biochem 1979, 249-256.
    • (1979) Curr Probl Clin Biochem , pp. 249-256
    • Heller, W.1    Harzmann, R.2    Bichler, K.H.3    Schmidt, K.4
  • 94
    • 0024379931 scopus 로고
    • Bone alkaline phosphatase isoenzyme and urinary hydroxyproline in healthy subjects, patients with osteolytic metastases, and patients with primary hyperparathyroidism
    • Stepan J.J., Mikulecky M., Bek V., Broulik P., Pacovsky V. Bone alkaline phosphatase isoenzyme and urinary hydroxyproline in healthy subjects, patients with osteolytic metastases, and patients with primary hyperparathyroidism. Neoplasma 1989, 36:495-501.
    • (1989) Neoplasma , vol.36 , pp. 495-501
    • Stepan, J.J.1    Mikulecky, M.2    Bek, V.3    Broulik, P.4    Pacovsky, V.5
  • 95
    • 0024446320 scopus 로고
    • Isoenzymes of alkaline and acid phosphatases as bones metastasis marker in breast cancer patients
    • Desoize B., Veiler V., Pourny C., Comoe L., Jardillier J.C. Isoenzymes of alkaline and acid phosphatases as bones metastasis marker in breast cancer patients. Anticancer Res 1989, 9:1105-1109.
    • (1989) Anticancer Res , vol.9 , pp. 1105-1109
    • Desoize, B.1    Veiler, V.2    Pourny, C.3    Comoe, L.4    Jardillier, J.C.5
  • 96
    • 0037861873 scopus 로고    scopus 로고
    • Evaluation of tartrate-resistant acid phosphatase (TRAP) 5b as serum marker of bone metastases in human breast cancer
    • Capeller B., Caffier H., Sutterlin M.W., Dietl J. Evaluation of tartrate-resistant acid phosphatase (TRAP) 5b as serum marker of bone metastases in human breast cancer. Anticancer Res 2003, 23:1011-1015.
    • (2003) Anticancer Res , vol.23 , pp. 1011-1015
    • Capeller, B.1    Caffier, H.2    Sutterlin, M.W.3    Dietl, J.4
  • 97
    • 0034073082 scopus 로고    scopus 로고
    • Prognostic value of serum markers of bone metabolism in untreated multiple myeloma patients
    • Fonseca R., Trendle M.C., Leong T., et al. Prognostic value of serum markers of bone metabolism in untreated multiple myeloma patients. Br J Haematol 2000, 109:24-29.
    • (2000) Br J Haematol , vol.109 , pp. 24-29
    • Fonseca, R.1    Trendle, M.C.2    Leong, T.3
  • 98
    • 0033059539 scopus 로고    scopus 로고
    • Serum bone alkaline phosphatase levels enhance the clinical utility of prostate specific antigen in the staging of newly diagnosed prostate cancer patients
    • Lorente J.A., Valenzuela H., Morote J., Gelabert A. Serum bone alkaline phosphatase levels enhance the clinical utility of prostate specific antigen in the staging of newly diagnosed prostate cancer patients. Eur J Nucl Med 1999, 26:625-632.
    • (1999) Eur J Nucl Med , vol.26 , pp. 625-632
    • Lorente, J.A.1    Valenzuela, H.2    Morote, J.3    Gelabert, A.4
  • 99
    • 34548389838 scopus 로고    scopus 로고
    • Predictors of skeletal complications in men with hormone-refractory metastatic prostate cancer
    • Smith M.R., Cook R.J., Coleman R., et al. Predictors of skeletal complications in men with hormone-refractory metastatic prostate cancer. Urology 2007, 70:315-319.
    • (2007) Urology , vol.70 , pp. 315-319
    • Smith, M.R.1    Cook, R.J.2    Coleman, R.3
  • 100
    • 33745203917 scopus 로고    scopus 로고
    • Markers of bone metabolism and survival in men with hormone-refractory metastatic prostate cancer
    • Cook R.J., Coleman R., Brown J., et al. Markers of bone metabolism and survival in men with hormone-refractory metastatic prostate cancer. Clin Cancer Res 2006, 12:3361-3367.
    • (2006) Clin Cancer Res , vol.12 , pp. 3361-3367
    • Cook, R.J.1    Coleman, R.2    Brown, J.3
  • 101
    • 0034661681 scopus 로고    scopus 로고
    • Predictors of skeletal complications in patients with metastatic breast carcinoma
    • Domchek S.M., Younger J., Finkelstein D.M., Seiden M.V. Predictors of skeletal complications in patients with metastatic breast carcinoma. Cancer 2000, 89:363-368.
    • (2000) Cancer , vol.89 , pp. 363-368
    • Domchek, S.M.1    Younger, J.2    Finkelstein, D.M.3    Seiden, M.V.4
  • 102
    • 0029800996 scopus 로고    scopus 로고
    • Expression of bone sialoprotein in primary human breast cancer is associated with poor survival
    • Bellahcene A., Menard S., Bufalino R., Moreau L., Castronovo V. Expression of bone sialoprotein in primary human breast cancer is associated with poor survival. Int J Cancer 1996, 69:350-353.
    • (1996) Int J Cancer , vol.69 , pp. 350-353
    • Bellahcene, A.1    Menard, S.2    Bufalino, R.3    Moreau, L.4    Castronovo, V.5
  • 103
    • 0021150369 scopus 로고
    • Clinical evaluation of bone turnover by serum osteocalcin measurements in a hospital setting
    • Slovik D.M., Gundberg C.M., Neer R.M., Lian J.B. Clinical evaluation of bone turnover by serum osteocalcin measurements in a hospital setting. J Clin Endocrinol Metab 1984, 59:228-230.
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 228-230
    • Slovik, D.M.1    Gundberg, C.M.2    Neer, R.M.3    Lian, J.B.4
  • 104
    • 43249128301 scopus 로고    scopus 로고
    • Zoledronic acid and survival in patients with metastatic bone disease from lung cancer and elevated markers of osteoclast activity
    • Hirsh V., Major P.P., Lipton A., et al. Zoledronic acid and survival in patients with metastatic bone disease from lung cancer and elevated markers of osteoclast activity. J Thorac Oncol 2008, 3:228-236.
    • (2008) J Thorac Oncol , vol.3 , pp. 228-236
    • Hirsh, V.1    Major, P.P.2    Lipton, A.3
  • 105
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial
    • Rosen L.S., Gordon D., Kaminski M., et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer 2003, 98:1735-1744.
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 106
    • 2642521168 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, phase III, double-blind, placebo-controlled trial
    • Rosen L.S., Gordon D., Tchekmedyian N.S., et al. Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, phase III, double-blind, placebo-controlled trial. Cancer 2004, 100:2613-2621.
    • (2004) Cancer , vol.100 , pp. 2613-2621
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, N.S.3
  • 107
    • 2942518111 scopus 로고    scopus 로고
    • Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
    • Saad F., Gleason D.M., Murray R., et al. Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst 2004, 96:879-882.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 879-882
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 108
    • 63749094012 scopus 로고    scopus 로고
    • Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
    • Fizazi K., Lipton A., Mariette X., et al. Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Clin Oncol 2009, 27:1564-1571.
    • (2009) J Clin Oncol , vol.27 , pp. 1564-1571
    • Fizazi, K.1    Lipton, A.2    Mariette, X.3
  • 109
    • 35348897212 scopus 로고    scopus 로고
    • Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases
    • Lipton A., Steger G.G., Figueroa J., et al. Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases. J Clin Oncol 2007, 25:4431-4437.
    • (2007) J Clin Oncol , vol.25 , pp. 4431-4437
    • Lipton, A.1    Steger, G.G.2    Figueroa, J.3
  • 110
    • 77953433829 scopus 로고    scopus 로고
    • Effects of the Src kinase inhibitor saracatinib (AZD0530) on bone turnover in healthy men: a randomized, double-blind, placebo-controlled, multiple-ascending-dose phase I trial
    • Hannon R.A., Clack G., Rimmer M., et al. Effects of the Src kinase inhibitor saracatinib (AZD0530) on bone turnover in healthy men: a randomized, double-blind, placebo-controlled, multiple-ascending-dose phase I trial. J Bone Miner Res 2010, 25:463-471.
    • (2010) J Bone Miner Res , vol.25 , pp. 463-471
    • Hannon, R.A.1    Clack, G.2    Rimmer, M.3
  • 111
    • 0022368763 scopus 로고
    • Anorexia and weight loss: indicators of cachexia in small cell lung cancer
    • Lindsey A.M., Piper B.F. Anorexia and weight loss: indicators of cachexia in small cell lung cancer. Nutr Cancer 1985, 7:65-76.
    • (1985) Nutr Cancer , vol.7 , pp. 65-76
    • Lindsey, A.M.1    Piper, B.F.2
  • 112
    • 33751522658 scopus 로고    scopus 로고
    • The circadian rhythm of biochemical markers of bone resorption is normally synchronized in breast cancer patients with bone lytic metastases independently of tumor load
    • Generali D., Berruti A., Tampellini M., et al. The circadian rhythm of biochemical markers of bone resorption is normally synchronized in breast cancer patients with bone lytic metastases independently of tumor load. Bone 2007, 40:182-188.
    • (2007) Bone , vol.40 , pp. 182-188
    • Generali, D.1    Berruti, A.2    Tampellini, M.3
  • 113
    • 33746838545 scopus 로고    scopus 로고
    • Usefulness of alpha1-antichymotrypsin-PSA complex for predicting bone metastases of prostate cancer
    • Kikuchi E., Nakashima J., Ishibashi M., et al. Usefulness of alpha1-antichymotrypsin-PSA complex for predicting bone metastases of prostate cancer. Urology 2006, 68:371-375.
    • (2006) Urology , vol.68 , pp. 371-375
    • Kikuchi, E.1    Nakashima, J.2    Ishibashi, M.3
  • 114
    • 33745862393 scopus 로고    scopus 로고
    • Prognostic significance of immunohistochemical expression of the HER-2/neu oncoprotein in bone metastatic prostate cancer
    • Nishio Y., Yamada Y., Kokubo H., et al. Prognostic significance of immunohistochemical expression of the HER-2/neu oncoprotein in bone metastatic prostate cancer. Urology 2006, 68:110-115.
    • (2006) Urology , vol.68 , pp. 110-115
    • Nishio, Y.1    Yamada, Y.2    Kokubo, H.3
  • 116
    • 0030670453 scopus 로고    scopus 로고
    • Clinical perspectives on the use of composite endpoints
    • discussion follows
    • Cannon C.P. Clinical perspectives on the use of composite endpoints. Control Clin Trials 1997, 18:517-529. discussion follows.
    • (1997) Control Clin Trials , vol.18 , pp. 517-529
    • Cannon, C.P.1
  • 117
    • 33645227163 scopus 로고    scopus 로고
    • Some issues with composite endpoints in clinical trials
    • Chi G.Y. Some issues with composite endpoints in clinical trials. Fundam Clin Pharmacol 2005, 19:609-619.
    • (2005) Fundam Clin Pharmacol , vol.19 , pp. 609-619
    • Chi, G.Y.1
  • 118
    • 34250017219 scopus 로고    scopus 로고
    • Methodologic discussions for using and interpreting composite endpoints are limited, but still identify major concerns
    • discussion follows
    • Ferreira-Gonzalez I., Permanyer-Miralda G., Busse J.W., et al. Methodologic discussions for using and interpreting composite endpoints are limited, but still identify major concerns. J Clin Epidemiol 2007, 60:651-657. discussion follows.
    • (2007) J Clin Epidemiol , vol.60 , pp. 651-657
    • Ferreira-Gonzalez, I.1    Permanyer-Miralda, G.2    Busse, J.W.3
  • 121
    • 0001646484 scopus 로고
    • Cox's regression model for counting processes: a large sample study
    • Andersen P.K., Gill R.D. Cox's regression model for counting processes: a large sample study. Ann Stat 1982, 10:1100-1120.
    • (1982) Ann Stat , vol.10 , pp. 1100-1120
    • Andersen, P.K.1    Gill, R.D.2
  • 123
    • 36849069347 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer
    • Harris L., Fritsche H., Mennel R., et al. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol 2007, 25:5287-5312.
    • (2007) J Clin Oncol , vol.25 , pp. 5287-5312
    • Harris, L.1    Fritsche, H.2    Mennel, R.3
  • 124
    • 0034062815 scopus 로고    scopus 로고
    • American Society of Clinical Oncology guideline on the role of bisphosphonates in breast cancer. American Society of Clinical Oncology Bisphosphonates Expert Panel
    • Hillner B.E., Ingle J.N., Berenson J.R., et al. American Society of Clinical Oncology guideline on the role of bisphosphonates in breast cancer. American Society of Clinical Oncology Bisphosphonates Expert Panel. J Clin Oncol 2000, 18:1378-1391.
    • (2000) J Clin Oncol , vol.18 , pp. 1378-1391
    • Hillner, B.E.1    Ingle, J.N.2    Berenson, J.R.3
  • 125
    • 35948993387 scopus 로고    scopus 로고
    • The use of bone markers in a 6-week study to assess the efficacy of oral clodronate in patients with metastatic bone disease
    • Brown J.E., McCloskey E.V., Dewar J.A., et al. The use of bone markers in a 6-week study to assess the efficacy of oral clodronate in patients with metastatic bone disease. Calcif Tissue Int 2007, 81:341-351.
    • (2007) Calcif Tissue Int , vol.81 , pp. 341-351
    • Brown, J.E.1    McCloskey, E.V.2    Dewar, J.A.3
  • 126
    • 0036533617 scopus 로고    scopus 로고
    • Extracellular matrix building marked by the N-terminal propeptide of procollagen type I reflect aggressiveness of recurrent breast cancer
    • Jensen B.V., Johansen J.S., Skovsgaard T., Brandt J., Teisner B. Extracellular matrix building marked by the N-terminal propeptide of procollagen type I reflect aggressiveness of recurrent breast cancer. Int J Cancer 2002, 98:582-589.
    • (2002) Int J Cancer , vol.98 , pp. 582-589
    • Jensen, B.V.1    Johansen, J.S.2    Skovsgaard, T.3    Brandt, J.4    Teisner, B.5
  • 127
    • 34250694556 scopus 로고    scopus 로고
    • Total procollagen type 1 amino-terminal propeptide (total P1NP) as a bone metastasis marker in gynecological carcinomas
    • Oremek G., Sauer-Eppel H., Klepzig M. Total procollagen type 1 amino-terminal propeptide (total P1NP) as a bone metastasis marker in gynecological carcinomas. Anticancer Res 2007, 27:1961-1962.
    • (2007) Anticancer Res , vol.27 , pp. 1961-1962
    • Oremek, G.1    Sauer-Eppel, H.2    Klepzig, M.3
  • 128
    • 30644457048 scopus 로고    scopus 로고
    • Serum amino-terminal propeptide of type 1 procollagen (P1NP) in prostate cancer: a potential predictor of bone metastases and prognosticator for disease progression and survival
    • Thurairaja R., Iles R.K., Jefferson K., McFarlane J.P., Persad R.A. Serum amino-terminal propeptide of type 1 procollagen (P1NP) in prostate cancer: a potential predictor of bone metastases and prognosticator for disease progression and survival. Urol Int 2006, 76:67-71.
    • (2006) Urol Int , vol.76 , pp. 67-71
    • Thurairaja, R.1    Iles, R.K.2    Jefferson, K.3    McFarlane, J.P.4    Persad, R.A.5
  • 129
    • 0031454187 scopus 로고    scopus 로고
    • Aggressive breast cancer leads to discrepant serum levels of the type I procollagen propeptides PINP and PICP
    • Jukkola A., Tahtela R., Tholix E., et al. Aggressive breast cancer leads to discrepant serum levels of the type I procollagen propeptides PINP and PICP. Cancer Res 1997, 57:5517-5520.
    • (1997) Cancer Res , vol.57 , pp. 5517-5520
    • Jukkola, A.1    Tahtela, R.2    Tholix, E.3
  • 130
    • 0033390826 scopus 로고    scopus 로고
    • Serum type I collagen degradation markers, ICTP and CrossLaps, are factors for poor survival in lung cancer
    • Ylisirnio S., Sassi M.L., Risteli J., Turpeenniemi-Hujanen T., Jukkola A. Serum type I collagen degradation markers, ICTP and CrossLaps, are factors for poor survival in lung cancer. Anticancer Res 1999, 19:5577-5581.
    • (1999) Anticancer Res , vol.19 , pp. 5577-5581
    • Ylisirnio, S.1    Sassi, M.L.2    Risteli, J.3    Turpeenniemi-Hujanen, T.4    Jukkola, A.5
  • 131
    • 75149173381 scopus 로고    scopus 로고
    • Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer
    • McCloskey E., Paterson A., Kanis J., Tahtela R., Powles T. Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer. Eur J Cancer 2010, 46:558-565.
    • (2010) Eur J Cancer , vol.46 , pp. 558-565
    • McCloskey, E.1    Paterson, A.2    Kanis, J.3    Tahtela, R.4    Powles, T.5
  • 132
    • 7144264425 scopus 로고    scopus 로고
    • Relationships between biochemical and symptomatic response in a double-blind randomised trial of pamidronate for metastatic bone disease
    • Vinholes J.J., Purohit O.P., Abbey M.E., Eastell R., Coleman R.E. Relationships between biochemical and symptomatic response in a double-blind randomised trial of pamidronate for metastatic bone disease. Ann Oncol 1997, 8:1243-1250.
    • (1997) Ann Oncol , vol.8 , pp. 1243-1250
    • Vinholes, J.J.1    Purohit, O.P.2    Abbey, M.E.3    Eastell, R.4    Coleman, R.E.5
  • 133
    • 77955560932 scopus 로고    scopus 로고
    • Bone-specific alkaline phosphatase (BSAP) and serum N-telopeptide (sNTX) as predictors of bone loss in postmenopausal women with early breast cancer receiving letrozole as adjuvant therapy: a 5-year study (Z-FAST)
    • [abstract 2067]
    • Brufsky A., Harker G., Beck T., et al. Bone-specific alkaline phosphatase (BSAP) and serum N-telopeptide (sNTX) as predictors of bone loss in postmenopausal women with early breast cancer receiving letrozole as adjuvant therapy: a 5-year study (Z-FAST). Cancer Res 2009, 69(Suppl.):176s. [abstract 2067].
    • (2009) Cancer Res , vol.69 , Issue.SUPPL.
    • Brufsky, A.1    Harker, G.2    Beck, T.3
  • 135
    • 0037259220 scopus 로고    scopus 로고
    • Cross-sectional study of bone turnover during bicalutamide monotherapy for prostate cancer
    • Smith M.R., Fallon M.A., Goode M.J. Cross-sectional study of bone turnover during bicalutamide monotherapy for prostate cancer. Urology 2003, 61:127-131.
    • (2003) Urology , vol.61 , pp. 127-131
    • Smith, M.R.1    Fallon, M.A.2    Goode, M.J.3
  • 136
    • 36349002794 scopus 로고    scopus 로고
    • Preventive effect of risedronate on bone loss in men receiving androgen-deprivation therapy for prostate cancer
    • Ishizaka K., Machida T., Kobayashi S., Kanbe N., Kitahara S., Yoshida K. Preventive effect of risedronate on bone loss in men receiving androgen-deprivation therapy for prostate cancer. Int J Urol 2007, 14:1071-1075.
    • (2007) Int J Urol , vol.14 , pp. 1071-1075
    • Ishizaka, K.1    Machida, T.2    Kobayashi, S.3    Kanbe, N.4    Kitahara, S.5    Yoshida, K.6
  • 137
    • 34249884844 scopus 로고    scopus 로고
    • The effect of zoledronic acid on bone mineral density in patients undergoing androgen deprivation therapy
    • Israeli R.S., Rosenberg S.J., Saltzstein D.R., et al. The effect of zoledronic acid on bone mineral density in patients undergoing androgen deprivation therapy. Clin Genitourin Cancer 2007, 5:271-277.
    • (2007) Clin Genitourin Cancer , vol.5 , pp. 271-277
    • Israeli, R.S.1    Rosenberg, S.J.2    Saltzstein, D.R.3
  • 138
    • 17144429310 scopus 로고    scopus 로고
    • Preventing bone loss during androgen deprivation therapy for prostate cancer: early experience with neridronate
    • discussion follows
    • Magno C., Anastasi G., Morabito N., et al. Preventing bone loss during androgen deprivation therapy for prostate cancer: early experience with neridronate. Eur Urol 2005, 47:575-580. discussion follows.
    • (2005) Eur Urol , vol.47 , pp. 575-580
    • Magno, C.1    Anastasi, G.2    Morabito, N.3
  • 139
    • 18644373689 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases
    • Chen T., Berenson J., Vescio R., et al. Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases. J Clin Pharmacol 2002, 42:1228-1236.
    • (2002) J Clin Pharmacol , vol.42 , pp. 1228-1236
    • Chen, T.1    Berenson, J.2    Vescio, R.3
  • 140
    • 0026320852 scopus 로고
    • Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure
    • Sato M., Grasser W., Endo N., et al. Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. J Clin Invest 1991, 88:2095-2105.
    • (1991) J Clin Invest , vol.88 , pp. 2095-2105
    • Sato, M.1    Grasser, W.2    Endo, N.3
  • 141
    • 0029164610 scopus 로고
    • Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models
    • Azuma Y., Sato H., Oue Y., et al. Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models. Bone 1995, 16:235-245.
    • (1995) Bone , vol.16 , pp. 235-245
    • Azuma, Y.1    Sato, H.2    Oue, Y.3
  • 142
    • 24144449851 scopus 로고    scopus 로고
    • Skeletal retention of bisphosphonate (pamidronate) and its relation to the rate of bone resorption in patients with breast cancer and bone metastases
    • Cremers S.C., Papapoulos S.E., Gelderblom H., et al. Skeletal retention of bisphosphonate (pamidronate) and its relation to the rate of bone resorption in patients with breast cancer and bone metastases. J Bone Miner Res 2005, 20:1543-1547.
    • (2005) J Bone Miner Res , vol.20 , pp. 1543-1547
    • Cremers, S.C.1    Papapoulos, S.E.2    Gelderblom, H.3
  • 143
    • 33646089442 scopus 로고    scopus 로고
    • Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite
    • Nancollas G.H., Tang R., Phipps R.J., et al. Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite. Bone 2006, 38:617-627.
    • (2006) Bone , vol.38 , pp. 617-627
    • Nancollas, G.H.1    Tang, R.2    Phipps, R.J.3
  • 144
    • 34147140893 scopus 로고    scopus 로고
    • Determinants of structure-function relationships among bisphosphonates
    • Russell R.G. Determinants of structure-function relationships among bisphosphonates. Bone 2007, 40:S21-S25.
    • (2007) Bone , vol.40
    • Russell, R.G.1
  • 145
    • 41949092083 scopus 로고    scopus 로고
    • Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells
    • Coxon F.P., Thompson K., Roelofs A.J., Ebetino F.H., Rogers M.J. Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells. Bone 2008, 42:848-860.
    • (2008) Bone , vol.42 , pp. 848-860
    • Coxon, F.P.1    Thompson, K.2    Roelofs, A.J.3    Ebetino, F.H.4    Rogers, M.J.5
  • 146
    • 84888441632 scopus 로고    scopus 로고
    • U.S. National Institutes of Health. Efficacy and safety of zoledronic acid (every 4weeks vs. every 12weeks) in patients with documented metastases from bone cancer, [accessed 18.08.10].
    • U.S. National Institutes of Health. Efficacy and safety of zoledronic acid (every 4weeks vs. every 12weeks) in patients with documented metastases from bone cancer, [accessed 18.08.10]. http://www.clinicaltrials.gov/ct2/show/NCT00320710.
  • 147
    • 84888475529 scopus 로고    scopus 로고
    • U.S. National Institutes of Health. Zoledronic acid treatment (every 4 or 12weeks) to prevent selected complications in advanced multiple myeloma patients (Z-MARK), [accessed 18.08.10].
    • U.S. National Institutes of Health. Zoledronic acid treatment (every 4 or 12weeks) to prevent selected complications in advanced multiple myeloma patients (Z-MARK), [accessed 18.08.10]. http://www.clinicaltrials.gov/ct2/show/NCT00622505.
  • 148
    • 84888464855 scopus 로고    scopus 로고
    • U.S. National Institutes of Health. Comparison of two schedules of zoledronic acid in treating patients with breast cancer that has spread to the bone, [accessed 18.08.10].
    • U.S. National Institutes of Health. Comparison of two schedules of zoledronic acid in treating patients with breast cancer that has spread to the bone, [accessed 18.08.10]. http://www.clinicaltrials.gov/ct2/show/NCT00458796.
  • 150
    • 0036842343 scopus 로고    scopus 로고
    • Evaluation of bone disease in multiple myeloma: a correlation between biochemical markers of bone metabolism and other clinical parameters in untreated multiple myeloma patients
    • Alexandrakis M.G., Passam F.H., Malliaraki N., Katachanakis C., Kyriakou D.S., Margioris A.N. Evaluation of bone disease in multiple myeloma: a correlation between biochemical markers of bone metabolism and other clinical parameters in untreated multiple myeloma patients. Clin Chim Acta 2002, 325:51-57.
    • (2002) Clin Chim Acta , vol.325 , pp. 51-57
    • Alexandrakis, M.G.1    Passam, F.H.2    Malliaraki, N.3    Katachanakis, C.4    Kyriakou, D.S.5    Margioris, A.N.6
  • 151
    • 0032902720 scopus 로고    scopus 로고
    • Evaluation of bone disease in multiple myeloma: a comparison between the resorption markers urinary deoxypyridinoline/creatinine (DPD) and serum ICTP, and an evaluation of the DPD/osteocalcin and ICTP/osteocalcin ratios
    • Carlson K., Larsson A., Simonsson B., Turesson I., Westin J., Ljunghall S. Evaluation of bone disease in multiple myeloma: a comparison between the resorption markers urinary deoxypyridinoline/creatinine (DPD) and serum ICTP, and an evaluation of the DPD/osteocalcin and ICTP/osteocalcin ratios. Eur J Haematol 1999, 62:300-306.
    • (1999) Eur J Haematol , vol.62 , pp. 300-306
    • Carlson, K.1    Larsson, A.2    Simonsson, B.3    Turesson, I.4    Westin, J.5    Ljunghall, S.6
  • 152
    • 33847615715 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover in diagnosis of myeloma bone disease
    • Dizdar O., Barista I., Kalyoncu U., et al. Biochemical markers of bone turnover in diagnosis of myeloma bone disease. Am J Hematol 2007, 82:185-191.
    • (2007) Am J Hematol , vol.82 , pp. 185-191
    • Dizdar, O.1    Barista, I.2    Kalyoncu, U.3
  • 153
    • 34548729630 scopus 로고    scopus 로고
    • Serum levels of OPG, RANKL and RANKL/OPG ratio in newly-diagnosed patients with multiple myeloma. Clinical correlations
    • Goranova-Marinova V., Goranov S., Pavlov P., Tzvetkova T. Serum levels of OPG, RANKL and RANKL/OPG ratio in newly-diagnosed patients with multiple myeloma. Clinical correlations. Haematologica 2007, 92:1000-1001.
    • (2007) Haematologica , vol.92 , pp. 1000-1001
    • Goranova-Marinova, V.1    Goranov, S.2    Pavlov, P.3    Tzvetkova, T.4
  • 154
    • 0036659918 scopus 로고    scopus 로고
    • Bone resorption parameters [carboxy-terminal telopeptide of type-I collagen (ICTP), amino-terminal collagen type-I telopeptide (NTx), and deoxypyridinoline (Dpd)] in MGUS and multiple myeloma
    • Jakob C., Zavrski I., Heider U., et al. Bone resorption parameters [carboxy-terminal telopeptide of type-I collagen (ICTP), amino-terminal collagen type-I telopeptide (NTx), and deoxypyridinoline (Dpd)] in MGUS and multiple myeloma. Eur J Haematol 2002, 69:37-42.
    • (2002) Eur J Haematol , vol.69 , pp. 37-42
    • Jakob, C.1    Zavrski, I.2    Heider, U.3
  • 155
    • 32144435917 scopus 로고    scopus 로고
    • The significance of carboxy-terminal telopeptide of type I collagen (ICTP) and osteocalcin (OC) in assessment of bone disease in patients with multiple myeloma
    • Kuliszkiewicz-Janus M., Malecki R., Zoltaszek A., Zastawny M. The significance of carboxy-terminal telopeptide of type I collagen (ICTP) and osteocalcin (OC) in assessment of bone disease in patients with multiple myeloma. Leuk Lymphoma 2005, 46:1749-1753.
    • (2005) Leuk Lymphoma , vol.46 , pp. 1749-1753
    • Kuliszkiewicz-Janus, M.1    Malecki, R.2    Zoltaszek, A.3    Zastawny, M.4
  • 156
    • 0043245842 scopus 로고    scopus 로고
    • Soluble receptor activator of nuclear factor kappaB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: proposal for a novel prognostic index
    • Terpos E., Szydlo R., Apperley J.F., et al. Soluble receptor activator of nuclear factor kappaB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: proposal for a novel prognostic index. Blood 2003, 102:1064-1069.
    • (2003) Blood , vol.102 , pp. 1064-1069
    • Terpos, E.1    Szydlo, R.2    Apperley, J.F.3
  • 157
    • 35748977950 scopus 로고    scopus 로고
    • Predictive value of alkaline phosphatase for response and time to progression in bortezomib-treated multiple myeloma patients
    • Zangari M., Esseltine D., Cavallo F., et al. Predictive value of alkaline phosphatase for response and time to progression in bortezomib-treated multiple myeloma patients. Am J Hematol 2007, 82:831-833.
    • (2007) Am J Hematol , vol.82 , pp. 831-833
    • Zangari, M.1    Esseltine, D.2    Cavallo, F.3
  • 158
    • 77952423759 scopus 로고    scopus 로고
    • Prognostic variables for survival and skeletal complications in patients with multiple myeloma osteolytic bone disease
    • Terpos E., Berenson J., Cook R.J., Lipton A., Coleman R.E. Prognostic variables for survival and skeletal complications in patients with multiple myeloma osteolytic bone disease. Leukemia 2010, 24:1043-1049.
    • (2010) Leukemia , vol.24 , pp. 1043-1049
    • Terpos, E.1    Berenson, J.2    Cook, R.J.3    Lipton, A.4    Coleman, R.E.5
  • 159
    • 77951056556 scopus 로고    scopus 로고
    • Multiple myeloma: changes in serum C-terminal telopeptide of collagen type I and bone-specific alkaline phosphatase can be used in daily practice to detect imminent osteolysis
    • Lund T., Abildgaard N., Andersen T.L., Delaisse J.M., Plesner T. Multiple myeloma: changes in serum C-terminal telopeptide of collagen type I and bone-specific alkaline phosphatase can be used in daily practice to detect imminent osteolysis. Eur J Haematol 2010, 84:412-420.
    • (2010) Eur J Haematol , vol.84 , pp. 412-420
    • Lund, T.1    Abildgaard, N.2    Andersen, T.L.3    Delaisse, J.M.4    Plesner, T.5
  • 160
    • 51649090583 scopus 로고    scopus 로고
    • Incorporation of the bone marker carboxy-terminal telopeptide of type-1 collagen improves prognostic information of the International Staging System in newly diagnosed symptomatic multiple myeloma
    • Jakob C., Sterz J., Liebisch P., et al. Incorporation of the bone marker carboxy-terminal telopeptide of type-1 collagen improves prognostic information of the International Staging System in newly diagnosed symptomatic multiple myeloma. Leukemia 2008, 22:1767-1772.
    • (2008) Leukemia , vol.22 , pp. 1767-1772
    • Jakob, C.1    Sterz, J.2    Liebisch, P.3
  • 161
    • 40849094250 scopus 로고    scopus 로고
    • The clinical significance of soluble human leukocyte antigen class-I, ICTP, and RANKL molecules in multiple myeloma patients
    • Schutt P., Rebmann V., Brandhorst D., et al. The clinical significance of soluble human leukocyte antigen class-I, ICTP, and RANKL molecules in multiple myeloma patients. Hum Immunol 2008, 69:79-87.
    • (2008) Hum Immunol , vol.69 , pp. 79-87
    • Schutt, P.1    Rebmann, V.2    Brandhorst, D.3
  • 162
    • 34548128339 scopus 로고    scopus 로고
    • The effect of novel anti-myeloma agents on bone metabolism of patients with multiple myeloma
    • Terpos E., Dimopoulos M.A., Sezer O. The effect of novel anti-myeloma agents on bone metabolism of patients with multiple myeloma. Leukemia 2007, 21:1875-1884.
    • (2007) Leukemia , vol.21 , pp. 1875-1884
    • Terpos, E.1    Dimopoulos, M.A.2    Sezer, O.3
  • 163
    • 27644523704 scopus 로고    scopus 로고
    • The combination of intermediate doses of thalidomide with dexamethasone is an effective treatment for patients with refractory/relapsed multiple myeloma and normalizes abnormal bone remodeling, through the reduction of sRANKL/osteoprotegerin ratio
    • Terpos E., Mihou D., Szydlo R., et al. The combination of intermediate doses of thalidomide with dexamethasone is an effective treatment for patients with refractory/relapsed multiple myeloma and normalizes abnormal bone remodeling, through the reduction of sRANKL/osteoprotegerin ratio. Leukemia 2005, 19:1969-1976.
    • (2005) Leukemia , vol.19 , pp. 1969-1976
    • Terpos, E.1    Mihou, D.2    Szydlo, R.3
  • 164
    • 57849161431 scopus 로고    scopus 로고
    • The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis
    • Terpos E., Kastritis E., Roussou M., et al. The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis. Leukemia 2008, 22:2247-2256.
    • (2008) Leukemia , vol.22 , pp. 2247-2256
    • Terpos, E.1    Kastritis, E.2    Roussou, M.3
  • 165
    • 21844463271 scopus 로고    scopus 로고
    • Usefulness of bone metabolic markers in the diagnosis of bone metastasis from lung cancer
    • Chung J.H., Park M.S., Kim Y.S., et al. Usefulness of bone metabolic markers in the diagnosis of bone metastasis from lung cancer. Yonsei Med J 2005, 46:388-393.
    • (2005) Yonsei Med J , vol.46 , pp. 388-393
    • Chung, J.H.1    Park, M.S.2    Kim, Y.S.3
  • 166
    • 6344284449 scopus 로고    scopus 로고
    • Comparison of bone scintigraphy with bone markers in the diagnosis of bone metastasis in lung carcinoma patients
    • Ebert W., Muley T., Herb K.P., Schmidt-Gayk H. Comparison of bone scintigraphy with bone markers in the diagnosis of bone metastasis in lung carcinoma patients. Anticancer Res 2004, 24:3193-3201.
    • (2004) Anticancer Res , vol.24 , pp. 3193-3201
    • Ebert, W.1    Muley, T.2    Herb, K.P.3    Schmidt-Gayk, H.4
  • 167
    • 33746724127 scopus 로고    scopus 로고
    • Serum TRACP 5b and ICTP as markers of bone metastases in breast cancer
    • Korpela J., Tiitinen S.L., Hiekkanen H., et al. Serum TRACP 5b and ICTP as markers of bone metastases in breast cancer. Anticancer Res 2006, 26:3127-3132.
    • (2006) Anticancer Res , vol.26 , pp. 3127-3132
    • Korpela, J.1    Tiitinen, S.L.2    Hiekkanen, H.3
  • 168
    • 0022404723 scopus 로고
    • Biochemical markers and skeletal metabolism in carcinoma of the prostate. Use of decision matrix theory and ROC analysis
    • Urwin G.H., Percival R.C., Yates A.J., et al. Biochemical markers and skeletal metabolism in carcinoma of the prostate. Use of decision matrix theory and ROC analysis. Br J Urol 1985, 57:711-714.
    • (1985) Br J Urol , vol.57 , pp. 711-714
    • Urwin, G.H.1    Percival, R.C.2    Yates, A.J.3
  • 169
    • 0035221804 scopus 로고    scopus 로고
    • Evaluation of bone metabolic markers in breast cancer with bone metastasis
    • Wada N., Fujisaki M., Ishii S., Ikeda T., Kitajima M. Evaluation of bone metabolic markers in breast cancer with bone metastasis. Breast Cancer 2001, 8:131-137.
    • (2001) Breast Cancer , vol.8 , pp. 131-137
    • Wada, N.1    Fujisaki, M.2    Ishii, S.3    Ikeda, T.4    Kitajima, M.5
  • 170
    • 0030939966 scopus 로고    scopus 로고
    • Diagnostic value of some biochemical bone markers for the detection of bone metastases in prostate cancer
    • Westerhuis L.W., Delaere K.P. Diagnostic value of some biochemical bone markers for the detection of bone metastases in prostate cancer. Eur J Clin Chem Clin Biochem 1997, 35:89-94.
    • (1997) Eur J Clin Chem Clin Biochem , vol.35 , pp. 89-94
    • Westerhuis, L.W.1    Delaere, K.P.2
  • 171
    • 36049031103 scopus 로고    scopus 로고
    • Beta-CTX and ICTP act as indicators of skeletal metastasis status in male patients with non-small cell lung cancer
    • Kong Q.Q., Sun T.W., Dou Q.Y., et al. Beta-CTX and ICTP act as indicators of skeletal metastasis status in male patients with non-small cell lung cancer. Int J Biol Markers 2007, 22:214-220.
    • (2007) Int J Biol Markers , vol.22 , pp. 214-220
    • Kong, Q.Q.1    Sun, T.W.2    Dou, Q.Y.3
  • 172
    • 61449228550 scopus 로고    scopus 로고
    • Procollagen type 1 amino-terminal propeptide: a marker for bone metastases in prostate carcinoma
    • Klepzig M., Jonas D., Oremek G.M. Procollagen type 1 amino-terminal propeptide: a marker for bone metastases in prostate carcinoma. Anticancer Res 2009, 29:671-673.
    • (2009) Anticancer Res , vol.29 , pp. 671-673
    • Klepzig, M.1    Jonas, D.2    Oremek, G.M.3
  • 173
    • 40149083563 scopus 로고    scopus 로고
    • Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel
    • Aapro M., Abrahamsson P.A., Body J.J., et al. Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel. Ann Oncol 2008, 19:420-432.
    • (2008) Ann Oncol , vol.19 , pp. 420-432
    • Aapro, M.1    Abrahamsson, P.A.2    Body, J.J.3
  • 174
    • 33750622369 scopus 로고    scopus 로고
    • Bone sialoprotein is predictive of bone metastases in resectable non-small-cell lung cancer: a retrospective case-control study
    • Papotti M., Kalebic T., Volante M., et al. Bone sialoprotein is predictive of bone metastases in resectable non-small-cell lung cancer: a retrospective case-control study. J Clin Oncol 2006, 24:4818-4824.
    • (2006) J Clin Oncol , vol.24 , pp. 4818-4824
    • Papotti, M.1    Kalebic, T.2    Volante, M.3
  • 175
    • 0029863676 scopus 로고    scopus 로고
    • Bone sialoprotein expression in primary human breast cancer is associated with bone metastases development
    • Bellahcene A., Kroll M., Liebens F., Castronovo V. Bone sialoprotein expression in primary human breast cancer is associated with bone metastases development. J Bone Miner Res 1996, 11:665-670.
    • (1996) J Bone Miner Res , vol.11 , pp. 665-670
    • Bellahcene, A.1    Kroll, M.2    Liebens, F.3    Castronovo, V.4
  • 176
    • 33745685865 scopus 로고    scopus 로고
    • Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of transforming growth factor beta in a mouse model of breast cancer
    • Nam J.S., Suchar A.M., Kang M.J., et al. Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of transforming growth factor beta in a mouse model of breast cancer. Cancer Res 2006, 66:6327-6335.
    • (2006) Cancer Res , vol.66 , pp. 6327-6335
    • Nam, J.S.1    Suchar, A.M.2    Kang, M.J.3
  • 177
    • 33845606215 scopus 로고    scopus 로고
    • Effects of bone sialoprotein on pancreatic cancer cell growth, invasion and metastasis
    • Kayed H., Kleeff J., Keleg S., et al. Effects of bone sialoprotein on pancreatic cancer cell growth, invasion and metastasis. Cancer Lett 2007, 245:171-183.
    • (2007) Cancer Lett , vol.245 , pp. 171-183
    • Kayed, H.1    Kleeff, J.2    Keleg, S.3
  • 178
    • 31544478560 scopus 로고    scopus 로고
    • Expression of dentin sialophosphoprotein in human prostate cancer and its correlation with tumor aggressiveness
    • Chaplet M., Waltregny D., Detry C., Fisher L.W., Castronovo V., Bellahcene A. Expression of dentin sialophosphoprotein in human prostate cancer and its correlation with tumor aggressiveness. Int J Cancer 2006, 118:850-856.
    • (2006) Int J Cancer , vol.118 , pp. 850-856
    • Chaplet, M.1    Waltregny, D.2    Detry, C.3    Fisher, L.W.4    Castronovo, V.5    Bellahcene, A.6
  • 179
    • 33846185823 scopus 로고    scopus 로고
    • PTHrP and bone sialoprotein as prognostic markers for developing bone metastases in breast cancer patients
    • Loibl S., Konigs A., Kaufmann M., Costa S.D., Bischoff J. PTHrP and bone sialoprotein as prognostic markers for developing bone metastases in breast cancer patients. Zentralbl Gynakol 2006, 128:330-335.
    • (2006) Zentralbl Gynakol , vol.128 , pp. 330-335
    • Loibl, S.1    Konigs, A.2    Kaufmann, M.3    Costa, S.D.4    Bischoff, J.5
  • 180
    • 56949108012 scopus 로고    scopus 로고
    • Her2-positive breast cancer: herceptin and beyond
    • Dean-Colomb W., Esteva F.J. Her2-positive breast cancer: herceptin and beyond. Eur J Cancer 2008, 44:2806-2812.
    • (2008) Eur J Cancer , vol.44 , pp. 2806-2812
    • Dean-Colomb, W.1    Esteva, F.J.2
  • 181
    • 33646820680 scopus 로고    scopus 로고
    • Expression of the calcium receptor in human breast cancer-a potential new marker predicting the risk of bone metastases
    • Mihai R., Stevens J., McKinney C., Ibrahim N.B. Expression of the calcium receptor in human breast cancer-a potential new marker predicting the risk of bone metastases. Eur J Surg Oncol 2006, 32:511-515.
    • (2006) Eur J Surg Oncol , vol.32 , pp. 511-515
    • Mihai, R.1    Stevens, J.2    McKinney, C.3    Ibrahim, N.B.4
  • 182
    • 32544449534 scopus 로고    scopus 로고
    • Prognostic value of stage IV neuroblastoma metastatic immunophenotype in the bone marrow: preliminary report
    • Nowicki M., Ostalska-Nowicka D., Miskowiak B. Prognostic value of stage IV neuroblastoma metastatic immunophenotype in the bone marrow: preliminary report. J Clin Pathol 2006, 59:150-152.
    • (2006) J Clin Pathol , vol.59 , pp. 150-152
    • Nowicki, M.1    Ostalska-Nowicka, D.2    Miskowiak, B.3
  • 183
    • 29744454928 scopus 로고    scopus 로고
    • Autocrine motility factor/glucose-6-phosphate isomerase is a possible predictor of metastasis in bone and soft tissue tumours
    • Dobashi Y., Watanabe H., Matsubara M., et al. Autocrine motility factor/glucose-6-phosphate isomerase is a possible predictor of metastasis in bone and soft tissue tumours. J Pathol 2006, 208:44-53.
    • (2006) J Pathol , vol.208 , pp. 44-53
    • Dobashi, Y.1    Watanabe, H.2    Matsubara, M.3
  • 184
    • 34250891436 scopus 로고    scopus 로고
    • Lactate dehydrogenase is a prognostic indicator for prostate cancer patients with bone metastasis
    • Naruse K., Yamada Y., Aoki S., et al. Lactate dehydrogenase is a prognostic indicator for prostate cancer patients with bone metastasis. Hinyokika Kiyo 2007, 53:287-292.
    • (2007) Hinyokika Kiyo , vol.53 , pp. 287-292
    • Naruse, K.1    Yamada, Y.2    Aoki, S.3
  • 185
    • 25844477041 scopus 로고    scopus 로고
    • Multiple myeloma: diagnosis and treatment
    • Rajkumar S.V., Kyle R.A. Multiple myeloma: diagnosis and treatment. Mayo Clin Proc 2005, 80:1371-1382.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1371-1382
    • Rajkumar, S.V.1    Kyle, R.A.2
  • 186
    • 34249064677 scopus 로고    scopus 로고
    • Serum concentrations of IL-2 and TNF-alpha in patients with painful bone metastases: correlation with responses to 89SrCl2 therapy
    • Fang N., Li Y., Xu Y.S., et al. Serum concentrations of IL-2 and TNF-alpha in patients with painful bone metastases: correlation with responses to 89SrCl2 therapy. J Nucl Med 2006, 47:242-246.
    • (2006) J Nucl Med , vol.47 , pp. 242-246
    • Fang, N.1    Li, Y.2    Xu, Y.S.3
  • 187
    • 70349093929 scopus 로고    scopus 로고
    • Markers of bone turnover (ICTP, NTX) and serum matrix metalloproteinase 1 (MMP1) as prognostic markers in breast cancer patients (BC) with bone metastases (BM) treated with bisphosphonates (BP)
    • [abstract 1024]
    • Costa L.A., Alho I., Casimiro S., et al. Markers of bone turnover (ICTP, NTX) and serum matrix metalloproteinase 1 (MMP1) as prognostic markers in breast cancer patients (BC) with bone metastases (BM) treated with bisphosphonates (BP). J Clin Oncol 2008, 26(Suppl.):47s. [abstract 1024].
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Costa, L.A.1    Alho, I.2    Casimiro, S.3
  • 188
    • 63149145552 scopus 로고    scopus 로고
    • Cystatin-C is an independent prognostic factor for survival in multiple myeloma and is reduced by bortezomib administration
    • Terpos E., Katodritou E., Tsiftsakis E., et al. Cystatin-C is an independent prognostic factor for survival in multiple myeloma and is reduced by bortezomib administration. Haematologica 2009, 94:372-379.
    • (2009) Haematologica , vol.94 , pp. 372-379
    • Terpos, E.1    Katodritou, E.2    Tsiftsakis, E.3


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