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Volumn 19, Issue 3, 2008, Pages 420-432

Guidance on the use of bisphosphonates in solid tumours: Recommendations of an international expert panel

(19)  Aapro, M a   Abrahamsson, P A b   Body, J J c   Coleman, R E d   Colomer, R e   Costa, L f   Crino L g   Dirix, L h   Gnant, M i   Gralow, J j   Hadji, P k   Hortobagyi, G N l   Jonat, W m   Lipton, A n   Monnier, A o   Paterson, A H G p   Rizzoli, R q   Saad, F r   Thurlimann B s  


Author keywords

Bisphosphonates; Bone; Cancer; CTIBL; Metastases; SRE

Indexed keywords

ALENDRONIC ACID; ANASTROZOLE; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CLODRONIC ACID; COLECALCIFEROL; CORTICOSTEROID; DOCETAXEL; ETIDRONIC ACID; GLUCOCORTICOID; GONADORELIN; GOSERELIN; IBANDRONIC ACID; IBUPROFEN; LETROZOLE; NONSTEROID ANTIINFLAMMATORY AGENT; PACLITAXEL; PAMIDRONIC ACID; PARACETAMOL; PLACEBO; PLATINUM COMPLEX; RISEDRONIC ACID; TAMOXIFEN; THALIDOMIDE; TILUDRONIC ACID; UNINDEXED DRUG; ZOLEDRONIC ACID;

EID: 40149083563     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdm442     Document Type: Review
Times cited : (413)

References (154)
  • 1
    • 0036148405 scopus 로고    scopus 로고
    • Development of bisphosphonates
    • Fleisch H. Development of bisphosphonates. Breast Cancer Res 2002; 4: 30-34.
    • (2002) Breast Cancer Res , vol.4 , pp. 30-34
    • Fleisch, H.1
  • 3
    • 5444242637 scopus 로고    scopus 로고
    • Bisphosphonates: Preclinical review
    • Green JR, Bisphosphonates: Preclinical review, Oncologist 2004; 9 (Suppl 4): 3-13.
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 4 , pp. 3-13
    • Green, J.R.1
  • 4
    • 0030601220 scopus 로고    scopus 로고
    • Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes
    • Rogers MJ, Brown RJ, Hodkin V et al. Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes. Biochem Biophys Res Commun 1996; 224: 863-869.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 863-869
    • Rogers, M.J.1    Brown, R.J.2    Hodkin, V.3
  • 5
    • 0031977199 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
    • Luckman SP, Hughes DE, Coxon FP et al. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res 1998; 13: 581-589.
    • (1998) J Bone Miner Res , vol.13 , pp. 581-589
    • Luckman, S.P.1    Hughes, D.E.2    Coxon, F.P.3
  • 6
    • 33645638181 scopus 로고    scopus 로고
    • Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells
    • Goffinet M, Thoulouzan M, Pradines A et al. Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells. BMC Cancer 2006; 6: 60.
    • (2006) BMC Cancer , vol.6 , pp. 60
    • Goffinet, M.1    Thoulouzan, M.2    Pradines, A.3
  • 7
    • 5444262558 scopus 로고    scopus 로고
    • Bisphosphonates: Clinical experience
    • Coleman RE. Bisphosphonates: Clinical experience. Oncologist 2004; 9 (Suppl 4): 14-27.
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 4 , pp. 14-27
    • Coleman, R.E.1
  • 8
    • 0030749321 scopus 로고    scopus 로고
    • Skeletal complications of malignancy
    • Coleman RE. Skeletal complications of malignancy. Cancer 1997; 80: 1588-1594.
    • (1997) Cancer , vol.80 , pp. 1588-1594
    • Coleman, R.E.1
  • 9
    • 0034660553 scopus 로고    scopus 로고
    • Current and future directions in medical therapy: Hypercalcemia
    • Body JJ. Current and future directions in medical therapy: hypercalcemia. Cancer 2000; 88: 3054-3058.
    • (2000) Cancer , vol.88 , pp. 3054-3058
    • Body, J.J.1
  • 10
    • 0942268815 scopus 로고    scopus 로고
    • Hypercalcemia of malignancy
    • Body JJ. Hypercalcemia of malignancy. Semin Nephrol 2004; 24: 48-54.
    • (2004) Semin Nephrol , vol.24 , pp. 48-54
    • Body, J.J.1
  • 11
    • 8444237485 scopus 로고    scopus 로고
    • Skeletal morbidity in men with prostate cancer: Quality-of-life considerations throughout the continuum of care
    • discussion 739-740
    • Saad F, Olsson C, Schulman CC. Skeletal morbidity in men with prostate cancer: Quality-of-life considerations throughout the continuum of care. Eur Urol 2004; 46: 731-739 discussion 739-740.
    • (2004) Eur Urol , vol.46 , pp. 731-739
    • Saad, F.1    Olsson, C.2    Schulman, C.C.3
  • 12
    • 1442279409 scopus 로고    scopus 로고
    • Health-related quality of life among patients with breast cancer receiving zoledronic acid or pamidronate disodium for metastatic bone lesions
    • Weinfurt KP, Castel LD, Li Y et al. Health-related quality of life among patients with breast cancer receiving zoledronic acid or pamidronate disodium for metastatic bone lesions. Med Care 2004; 42: 164-175.
    • (2004) Med Care , vol.42 , pp. 164-175
    • Weinfurt, K.P.1    Castel, L.D.2    Li, Y.3
  • 13
    • 20344387828 scopus 로고    scopus 로고
    • Zoledronic acid significantly improves pain scores and quality of life in breast cancer patients with bone metastases: A randomised, crossover study of community vs hospital bisphosphonate administration
    • Wardley A, Davidson N, Barrett-Lee P et al. Zoledronic acid significantly improves pain scores and quality of life in breast cancer patients with bone metastases: A randomised, crossover study of community vs hospital bisphosphonate administration. Br J Cancer 2005; 92. 1869-1876.
    • (2005) Br J Cancer , vol.92 , pp. 1869-1876
    • Wardley, A.1    Davidson, N.2    Barrett-Lee, P.3
  • 14
    • 13844314054 scopus 로고    scopus 로고
    • The cost of treatment of skeletal- related events in patients with bone metastases from lung cancer
    • Delea T, Langer C, McKiernan J et al, The cost of treatment of skeletal- related events in patients with bone metastases from lung cancer. Oncology 2004; 67: 390-396.
    • (2004) Oncology , vol.67 , pp. 390-396
    • Delea, T.1    Langer, C.2    McKiernan, J.3
  • 15
    • 33947610096 scopus 로고    scopus 로고
    • Managing metastatic bone pain: The role of bisphosphonates
    • Gralow J, Tripathy D, Managing metastatic bone pain: The role of bisphosphonates. J Pain Symptom Manage 2007; 33: 462-472.
    • (2007) J Pain Symptom Manage , vol.33 , pp. 462-472
    • Gralow, J.1    Tripathy, D.2
  • 16
    • 33745622153 scopus 로고    scopus 로고
    • Cost effectiveness of bisphosphonates in the management of breast cancer patients with bone metastases
    • Botteman M, Barghout V, Stephens J et al. Cost effectiveness of bisphosphonates in the management of breast cancer patients with bone metastases. Ann Oncol 2006; 17: 1072-1082.
    • (2006) Ann Oncol , vol.17 , pp. 1072-1082
    • Botteman, M.1    Barghout, V.2    Stephens, J.3
  • 17
    • 25844513080 scopus 로고    scopus 로고
    • Cost-effectiveness of oral ibandronate versus IV zoledronic acid or IV pamidronate for bone metastases in patients receiving oral hormonal therapy for breast cancer in the United Kingdom
    • De Cock E, Hutton J, Canney P et al. Cost-effectiveness of oral ibandronate versus IV zoledronic acid or IV pamidronate for bone metastases in patients receiving oral hormonal therapy for breast cancer in the United Kingdom. Clin Ther 2005; 27: 1295-1310.
    • (2005) Clin Ther , vol.27 , pp. 1295-1310
    • De Cock, E.1    Hutton, J.2    Canney, P.3
  • 18
    • 33847316862 scopus 로고    scopus 로고
    • Souberbielle B, Williams R, McCloskey E. The cost-effectiveness of bisphosphonates in metastatic breast cancer: Letter to the editor in response to Botteman et al. 2006. Ann Oncol 2007; 18: 393.
    • Souberbielle B, Williams R, McCloskey E. The cost-effectiveness of bisphosphonates in metastatic breast cancer: Letter to the editor in response to Botteman et al. 2006. Ann Oncol 2007; 18: 393.
  • 19
    • 33947539707 scopus 로고    scopus 로고
    • Zoledronic acid prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: A report from the Austrian Breast and Colorectal Cancer Study Group
    • Gnant MF, Mlineritsch B, Luschin-Elbengreuth G et al. Zoledronic acid prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: A report from the Austrian Breast and Colorectal Cancer Study Group. J Clin Oncol 2007; 25: 820-828.
    • (2007) J Clin Oncol , vol.25 , pp. 820-828
    • Gnant, M.F.1    Mlineritsch, B.2    Luschin-Elbengreuth, G.3
  • 20
    • 33646793674 scopus 로고    scopus 로고
    • Management of cancer-treatment-induced bone loss in postmenopausal women undergoing adjuvant breast cancer therapy: A Z-FAST update
    • Brufsky A. Management of cancer-treatment-induced bone loss in postmenopausal women undergoing adjuvant breast cancer therapy: A Z-FAST update. Semin Oncol 2006; 33: S13-S17.
    • (2006) Semin Oncol , vol.33
    • Brufsky, A.1
  • 21
    • 33947524592 scopus 로고    scopus 로고
    • Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer
    • Brufsky A, Harker WG, Beck JT et al. Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer. J Clin Oncol 2007; 25: 829-836.
    • (2007) J Clin Oncol , vol.25 , pp. 829-836
    • Brufsky, A.1    Harker, W.G.2    Beck, J.T.3
  • 22
    • 33750717851 scopus 로고    scopus 로고
    • Oral bisphosphonates as adjuvant therapy for operable breast cancer
    • Powles T, McCroskey E, Paterson A. Oral bisphosphonates as adjuvant therapy for operable breast cancer. Clin Cancer Res 2006; 12: 6301s-6304s.
    • (2006) Clin Cancer Res , vol.12
    • Powles, T.1    McCroskey, E.2    Paterson, A.3
  • 23
    • 0034854065 scopus 로고    scopus 로고
    • Bisphosphonates in the prevention of bone metastases: Current evidence
    • Diel IJ. Bisphosphonates in the prevention of bone metastases: Current evidence. Semin Oncol 2001; 28: 75-80.
    • (2001) Semin Oncol , vol.28 , pp. 75-80
    • Diel, I.J.1
  • 24
    • 0035010803 scopus 로고    scopus 로고
    • Metastatic bone disease: Clinical features, pathophysiology and treatment strategies
    • Coleman RE, Metastatic bone disease: Clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 2001; 27: 165-176.
    • (2001) Cancer Treat Rev , vol.27 , pp. 165-176
    • Coleman, R.E.1
  • 25
    • 40149091934 scopus 로고    scopus 로고
    • Hei YJ, Saad F, Coleman RE, Chen YM. Fractures negatively affect survival in patients with bone metastases from breast cancer. Breast Cancer Res Treat 2005; 94: (Abstr-6036).
    • Hei YJ, Saad F, Coleman RE, Chen YM. Fractures negatively affect survival in patients with bone metastases from breast cancer. Breast Cancer Res Treat 2005; 94: (Abstr-6036).
  • 26
    • 20644449488 scopus 로고    scopus 로고
    • Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: A randomized, placebo-controlled trial
    • Kohno N, Aogi K, Minami H et al. Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: A randomized, placebo-controlled trial. J Clin Oncol 2005; 23: 3314-3321.
    • (2005) J Clin Oncol , vol.23 , pp. 3314-3321
    • Kohno, N.1    Aogi, K.2    Minami, H.3
  • 27
    • 40149083981 scopus 로고    scopus 로고
    • Wong R, Wiffen PJ. Bisphosphonates for the relief of pain secondary to bone metastases (Cochrane Review). The Cochrane Library. Chichester, UK: John Wiley & Sons 2004; 1-59.
    • Wong R, Wiffen PJ. Bisphosphonates for the relief of pain secondary to bone metastases (Cochrane Review). The Cochrane Library. Chichester, UK: John Wiley & Sons 2004; 1-59.
  • 28
    • 4444337297 scopus 로고    scopus 로고
    • Oral ibandronate improves bone pain and preserves quality of life in patients with skeletal metastases due to breast cancer
    • Body JJ, Diel IJ, Bell R et al. Oral ibandronate improves bone pain and preserves quality of life in patients with skeletal metastases due to breast cancer. Pain 2004; 111: 306-312.
    • (2004) Pain , vol.111 , pp. 306-312
    • Body, J.J.1    Diel, I.J.2    Bell, R.3
  • 29
    • 7144223389 scopus 로고    scopus 로고
    • Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate. Protocol 19 Aredia Breast Cancer Study Group
    • Hortobagyi GN, Theriault RL, Lipton A et al. Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate. Protocol 19 Aredia Breast Cancer Study Group. J Clin Oncol 1998; 16: 2038-2044.
    • (1998) J Clin Oncol , vol.16 , pp. 2038-2044
    • Hortobagyi, G.N.1    Theriault, R.L.2    Lipton, A.3
  • 30
    • 17144447171 scopus 로고    scopus 로고
    • Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases
    • Body JJ, Diel IJ, Lichinitser MR et al. Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases. Ann Oncol 2003; 14: 1399-1405.
    • (2003) Ann Oncol , vol.14 , pp. 1399-1405
    • Body, J.J.1    Diel, I.J.2    Lichinitser, M.R.3
  • 31
    • 1942501727 scopus 로고    scopus 로고
    • Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: Results from two randomised, placebo-controlled phase III studies
    • Body JJ, Diel IJ, Lichinitser MR et al. Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: Results from two randomised, placebo-controlled phase III studies. Br J Cancer 2004; 90: 1133-1137.
    • (2004) Br J Cancer , vol.90 , pp. 1133-1137
    • Body, J.J.1    Diel, I.J.2    Lichinitser, M.R.3
  • 32
    • 0032798648 scopus 로고    scopus 로고
    • Oral clodronate in breast cancer patients with bone metastases: A randomized study
    • Kristensen B, Ejlertsen B, Groenvold M et al. Oral clodronate in breast cancer patients with bone metastases: A randomized study. J Intern Med 1999; 246: 67-74.
    • (1999) J Intern Med , vol.246 , pp. 67-74
    • Kristensen, B.1    Ejlertsen, B.2    Groenvold, M.3
  • 33
    • 0027531814 scopus 로고
    • Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer
    • Paterson AH, Powles TJ, Kanis JA et al. Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer, J Clin Oncol 1993; 11: 59-65.
    • (1993) J Clin Oncol , vol.11 , pp. 59-65
    • Paterson, A.H.1    Powles, T.J.2    Kanis, J.A.3
  • 34
    • 17444435152 scopus 로고    scopus 로고
    • Double-blinded controlled study comparing clodronate versus placebo in patients with breast cancer bone metastases
    • Tubiana-Hulin M, Beuzeboc P, Mauriac L et al. Double-blinded controlled study comparing clodronate versus placebo in patients with breast cancer bone metastases. Bull Cancer 2001; 88: 701-707.
    • (2001) Bull Cancer , vol.88 , pp. 701-707
    • Tubiana-Hulin, M.1    Beuzeboc, P.2    Mauriac, L.3
  • 35
    • 0033050818 scopus 로고    scopus 로고
    • Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group
    • Theriault RL, Lipton A, Hortobagyi GN et al. Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group. J Clin Oncol 1999; 17: 846-854.
    • (1999) J Clin Oncol , vol.17 , pp. 846-854
    • Theriault, R.L.1    Lipton, A.2    Hortobagyi, G.N.3
  • 36
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial. Cancer 2003; 98: 1735-1744.
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 38
    • 33750693720 scopus 로고    scopus 로고
    • Breast cancer: Bisphosphonate therapy for metastatic bone disease
    • Body J-J. Breast cancer: Bisphosphonate therapy for metastatic bone disease. Clin Cancer Res 2006; 12: 6258s-6263s.
    • (2006) Clin Cancer Res , vol.12
    • Body, J.-J.1
  • 39
    • 0034162528 scopus 로고    scopus 로고
    • Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: Long term follow-up of two randomized, placebo-controlled trials
    • Lipton A, Theriault RL, Hortobagyi GN et al. Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: Long term follow-up of two randomized, placebo-controlled trials, Cancer 2000; 88: 1082-1090.
    • (2000) Cancer , vol.88 , pp. 1082-1090
    • Lipton, A.1    Theriault, R.L.2    Hortobagyi, G.N.3
  • 40
    • 0035463593 scopus 로고    scopus 로고
    • Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial
    • Rosen LS, Gordon D, Kaminski M et al. Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial. Cancer J 2001; 7: 377-387.
    • (2001) Cancer J , vol.7 , pp. 377-387
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 41
    • 10744233992 scopus 로고    scopus 로고
    • Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion
    • Rosen LS, Gordon DH, Dugan W Jr et al. Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion, Cancer 2004; 100: 36-43.
    • (2004) Cancer , vol.100 , pp. 36-43
    • Rosen, L.S.1    Gordon, D.H.2    Dugan Jr, W.3
  • 42
    • 34547840272 scopus 로고    scopus 로고
    • Oral ibandronate is as active as intravenous zoledronic acid for reducing bone turnover markers in women with breast cancer and bone metastases
    • Body JJ, Lichnnitser M, Tjulandin S et al. Oral ibandronate is as active as intravenous zoledronic acid for reducing bone turnover markers in women with breast cancer and bone metastases. Ann Oncol 2007; 18 (7): 1165-1170.
    • (2007) Ann Oncol , vol.18 , Issue.7 , pp. 1165-1170
    • Body, J.J.1    Lichnnitser, M.2    Tjulandin, S.3
  • 43
    • 0025770352 scopus 로고
    • Treatment of skeletal disease in breast cancer with clodronate
    • Paterson AH, Ernst DS, Powles TJ et al. Treatment of skeletal disease in breast cancer with clodronate. Bone 1991; 12 (Suppl 1): S25-S30.
    • (1991) Bone , vol.12 , Issue.SUPPL. 1
    • Paterson, A.H.1    Ernst, D.S.2    Powles, T.J.3
  • 45
    • 0026633284 scopus 로고
    • Effect of oral clodronate on bone pain. A controlled study in patients with metastic prostatic cancer
    • Elomaa I, Kylmala T, Tammela T et al. Effect of oral clodronate on bone pain. A controlled study in patients with metastic prostatic cancer. Int Urol Nephrol 1992; 24: 159-166.
    • (1992) Int Urol Nephrol , vol.24 , pp. 159-166
    • Elomaa, I.1    Kylmala, T.2    Tammela, T.3
  • 46
    • 0042331464 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial)
    • Dearnaley DP, Sydes MR, Mason MD et al. A double-blind, placebo-controlled, randomized trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial). J Natl Cancer Inst 2003; 95: 1300-1311.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1300-1311
    • Dearnaley, D.P.1    Sydes, M.R.2    Mason, M.D.3
  • 47
    • 0030955855 scopus 로고    scopus 로고
    • A randomized, controlled trial of intravenous clodronate in patients with metastatic bone disease and pain
    • Ernst DS, Brasher P, Hagen N et al. A randomized, controlled trial of intravenous clodronate in patients with metastatic bone disease and pain. J Pain Symptom Manage 1997; 13: 319-326.
    • (1997) J Pain Symptom Manage , vol.13 , pp. 319-326
    • Ernst, D.S.1    Brasher, P.2    Hagen, N.3
  • 48
    • 0024557878 scopus 로고
    • Palliation of painful bone metastases from prostate cancer using sodium etidronate: Results of a randomized, prospective, double-blind, placebo-controlled study
    • Smith JA Jr. Palliation of painful bone metastases from prostate cancer using sodium etidronate: Results of a randomized, prospective, double-blind, placebo-controlled study. J Urol 1989; 141: 85-87.
    • (1989) J Urol , vol.141 , pp. 85-87
    • Smith Jr., J.A.1
  • 49
    • 0036393344 scopus 로고    scopus 로고
    • Ibandronate in the treatment of prostate cancer associated painful osseous metastases
    • Heidenreich A, Elert A, Hofmann R. Ibandronate in the treatment of prostate cancer associated painful osseous metastases. Prostate Cancer Prostatic Dis 2002; 5: 231-235.
    • (2002) Prostate Cancer Prostatic Dis , vol.5 , pp. 231-235
    • Heidenreich, A.1    Elert, A.2    Hofmann, R.3
  • 51
    • 0642337996 scopus 로고    scopus 로고
    • Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer
    • Small EJ, Smith MR, Seaman JJ et al. Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer. J Clin Oncol 2003; 21: 4277-4284.
    • (2003) J Clin Oncol , vol.21 , pp. 4277-4284
    • Small, E.J.1    Smith, M.R.2    Seaman, J.J.3
  • 52
    • 2942518111 scopus 로고    scopus 로고
    • Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
    • Saad F, Gleason DM, Murray R et al. Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst 2004; 96: 879-882.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 879-882
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 53
    • 22544442188 scopus 로고    scopus 로고
    • Clinical benefit of zoledronic acid for the prevention of skeletal complications in advanced prostate cancer
    • Saad F. Clinical benefit of zoledronic acid for the prevention of skeletal complications in advanced prostate cancer. Clin Prostate Cancer 2005; 4: 31-37.
    • (2005) Clin Prostate Cancer , vol.4 , pp. 31-37
    • Saad, F.1
  • 54
    • 0037009822 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma
    • Saad F, Gleason DM, Murray R et al. A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma. J Natl Cancer Inst 2002; 94: 1458-1468.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1458-1468
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 55
    • 0141688330 scopus 로고    scopus 로고
    • Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain
    • Ernst DS, Tannock IF, Winquist EW et al. Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain. J Clin Oncol 2003; 21: 3335-3342.
    • (2003) J Clin Oncol , vol.21 , pp. 3335-3342
    • Ernst, D.S.1    Tannock, I.F.2    Winquist, E.W.3
  • 57
    • 34247230262 scopus 로고    scopus 로고
    • Bisphosphonates can prevent skeletal complications of malignant bone disease from prostate cancer and renal cell carcinoma
    • Saad F. Bisphosphonates can prevent skeletal complications of malignant bone disease from prostate cancer and renal cell carcinoma. Eur Urol Suppl 2007; 6: 683-688.
    • (2007) Eur Urol Suppl , vol.6 , pp. 683-688
    • Saad, F.1
  • 58
    • 0042914647 scopus 로고    scopus 로고
    • Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial - the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group
    • Rosen LS, Gordon D, Tchekmedyian S et al. Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial - the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group. J Clin Oncol 2003; 21: 3150-3157.
    • (2003) J Clin Oncol , vol.21 , pp. 3150-3157
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, S.3
  • 59
    • 2642521168 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: A randomized, phase III, double-blind, placebo-controlled trial
    • Rosen LS, Gordon D, Tchekmedyian NS et al. Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: A randomized, phase III, double-blind, placebo-controlled trial. Cancer 2004; 100: 2613-2621.
    • (2004) Cancer , vol.100 , pp. 2613-2621
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, N.S.3
  • 60
    • 0035433874 scopus 로고    scopus 로고
    • The skeletal metastatic complications of renal cell carcinoma
    • Zekri J, Ahmed N, Coleman RE, Hancock BW. The skeletal metastatic complications of renal cell carcinoma. Int J Oncol 2001; 19: 379-382.
    • (2001) Int J Oncol , vol.19 , pp. 379-382
    • Zekri, J.1    Ahmed, N.2    Coleman, R.E.3    Hancock, B.W.4
  • 61
    • 27144460580 scopus 로고    scopus 로고
    • Efficacy of ibandronate in metastatic bone disease: Review of clinical data
    • Bell R. Efficacy of ibandronate in metastatic bone disease: Review of clinical data. Oncologist 2005; 10 (Suppl 1): 8-13.
    • (2005) Oncologist , vol.10 , Issue.SUPPL. 1 , pp. 8-13
    • Bell, R.1
  • 62
    • 13144294096 scopus 로고    scopus 로고
    • A double blind randomized study of oral clodronate in the treatment of bone metastases from tumors poorly responsive to chemotherapy
    • Piga A, Bracci R, Ferretti B et al. A double blind randomized study of oral clodronate in the treatment of bone metastases from tumors poorly responsive to chemotherapy. J Exp Clin Cancer Res 1998; 17: 213-217.
    • (1998) J Exp Clin Cancer Res , vol.17 , pp. 213-217
    • Piga, A.1    Bracci, R.2    Ferretti, B.3
  • 65
    • 33645073160 scopus 로고    scopus 로고
    • Emkey RD, Ettinger M. Improving compliance and persistence with bisphosphonate therapy for osteoporosis. Am J Med 2006; 119: S18-S-24.
    • Emkey RD, Ettinger M. Improving compliance and persistence with bisphosphonate therapy for osteoporosis. Am J Med 2006; 119: S18-S-24.
  • 66
    • 34347406006 scopus 로고    scopus 로고
    • A systematic review of persistence and compliance with bisphosphonates for osteoporosis
    • Cramer JA, Gold DT, Silverman SL et al. A systematic review of persistence and compliance with bisphosphonates for osteoporosis. Osteoporos Int 2007; 18 (8): 1023-1031.
    • (2007) Osteoporos Int , vol.18 , Issue.8 , pp. 1023-1031
    • Cramer, J.A.1    Gold, D.T.2    Silverman, S.L.3
  • 67
    • 33846063769 scopus 로고    scopus 로고
    • Patient preference and adherence: Comparative US studies between two bisphosphonates, weekly risedronate and monthly ibandronate
    • Gold DT, Safi W, Trinh H. Patient preference and adherence: Comparative US studies between two bisphosphonates, weekly risedronate and monthly ibandronate. Curr Med Res Opin 2006; 22: 2383-2391.
    • (2006) Curr Med Res Opin , vol.22 , pp. 2383-2391
    • Gold, D.T.1    Safi, W.2    Trinh, H.3
  • 68
    • 33746164723 scopus 로고    scopus 로고
    • Treatment persistence with once-monthly ibandronate and patient support vs. once-weekly alendronate: Results from the PERSIST study
    • Cooper A, Drake J, Brankin E. Treatment persistence with once-monthly ibandronate and patient support vs. once-weekly alendronate: Results from the PERSIST study. Int J Clin Pract 2006; 60: 896-905.
    • (2006) Int J Clin Pract , vol.60 , pp. 896-905
    • Cooper, A.1    Drake, J.2    Brankin, E.3
  • 69
    • 40149101505 scopus 로고    scopus 로고
    • Poor persistency with oral bisphosphonates in cancer patients with bone metastasis
    • Göl D. Poor persistency with oral bisphosphonates in cancer patients with bone metastasis. Proc Am Soc Clin Oncol 2004 (Abstr 8221).
    • Proc Am Soc Clin Oncol 2004 (Abstr , vol.8221
    • Göl, D.1
  • 70
    • 36549012194 scopus 로고    scopus 로고
    • Higher persistency with i.v. bisphosphonates in patients with bone metastasis
    • Mangiapane S, Hoer A, Gothe H et al. Higher persistency with i.v. bisphosphonates in patients with bone metastasis. ASCO Meeting Abstracts 2006; 24: 18623.
    • (2006) ASCO Meeting Abstracts , vol.24 , pp. 18623
    • Mangiapane, S.1    Hoer, A.2    Gothe, H.3
  • 71
    • 20844457304 scopus 로고    scopus 로고
    • Bisphosphonate infusions: Patient preference, safety and clinic use
    • Chem B, Joseph D, Joshua D et al. Bisphosphonate infusions: Patient preference, safety and clinic use. Support Care Cancer 2004; 12: 463-466.
    • (2004) Support Care Cancer , vol.12 , pp. 463-466
    • Chem, B.1    Joseph, D.2    Joshua, D.3
  • 74
    • 40149086931 scopus 로고    scopus 로고
    • Bondronat (ibandronic acid), Summary of Product Characteristics, 5 (IA) (cU/1/96/012/004 and EU/1/96/009-013). Welwyn Garden City, UK: Roche Registration, Ltd. Updated on March 6, 2007 based on EMEA/H/C/101/IA/043.
    • Bondronat (ibandronic acid), Summary of Product Characteristics, 5 (IA) (cU/1/96/012/004 and EU/1/96/009-013). Welwyn Garden City, UK: Roche Registration, Ltd. Updated on March 6, 2007 based on EMEA/H/C/101/IA/043.
  • 75
    • 0036937023 scopus 로고    scopus 로고
    • Bisphosphonates for cancer patients: Why, how, and when?
    • Body JJ, Mancini I. Bisphosphonates for cancer patients: Why, how, and when? Support Care Cancer 2002; 10: 399-407.
    • (2002) Support Care Cancer , vol.10 , pp. 399-407
    • Body, J.J.1    Mancini, I.2
  • 76
    • 10244250263 scopus 로고    scopus 로고
    • Clinical benefit of zoledronic acid in patients with lung cancer and other solid tumors: Analysis based on history of skeletal complications
    • Hirsh V, Tchekmedyian NS, Rosen LS et al. Clinical benefit of zoledronic acid in patients with lung cancer and other solid tumors: Analysis based on history of skeletal complications. Clin Lung Cancer 2004; 6: 170-174.
    • (2004) Clin Lung Cancer , vol.6 , pp. 170-174
    • Hirsh, V.1    Tchekmedyian, N.S.2    Rosen, L.S.3
  • 77
    • 33750605957 scopus 로고    scopus 로고
    • Phase II trial evaluating the palliative benefit of second-line zoledronic acid in breast cancer patients with either a skeletal-related event or progressive bone metastases despite first-line bisphosphonate therapy
    • Clemons MJ, Dranitsaris G, Ooi WS et al. Phase II trial evaluating the palliative benefit of second-line zoledronic acid in breast cancer patients with either a skeletal-related event or progressive bone metastases despite first-line bisphosphonate therapy. J Clin Oncol 2006; 24; 4895-4900.
    • (2006) J Clin Oncol , vol.24 , pp. 4895-4900
    • Clemons, M.J.1    Dranitsaris, G.2    Ooi, W.S.3
  • 79
    • 24644479228 scopus 로고    scopus 로고
    • Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledrionic acid
    • Coleman RE, Major P, Lipton A et al. Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledrionic acid. J Clin Oncol 2005; 23: 4925-4935.
    • (2005) J Clin Oncol , vol.23 , pp. 4925-4935
    • Coleman, R.E.1    Major, P.2    Lipton, A.3
  • 80
    • 33750726077 scopus 로고    scopus 로고
    • Clinical features of metastatic bone disease and risk of skeletal morbidity
    • Coleman RE. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 2006; 12: 6243s-6249s.
    • (2006) Clin Cancer Res , vol.12
    • Coleman, R.E.1
  • 81
    • 33745203917 scopus 로고    scopus 로고
    • Markers of bone metabolism and survival in men with hormone-refractory metastatic prostate cancer
    • Cook RJ, Coleman R, Brown J et al. Markers of bone metabolism and survival in men with hormone-refractory metastatic prostate cancer, Clin Cancer Res 2006; 12: 3361-3367.
    • (2006) Clin Cancer Res , vol.12 , pp. 3361-3367
    • Cook, R.J.1    Coleman, R.2    Brown, J.3
  • 82
    • 33847637152 scopus 로고    scopus 로고
    • International Society of Geriatric Oncology (SIOG) clinical practice recommendations for the use of bisphosphonates in elderly patients
    • Body JJ, Coleman R, Clezardin P et al. International Society of Geriatric Oncology (SIOG) clinical practice recommendations for the use of bisphosphonates in elderly patients. Eur J Cancer 2007; 43: 852-858.
    • (2007) Eur J Cancer , vol.43 , pp. 852-858
    • Body, J.J.1    Coleman, R.2    Clezardin, P.3
  • 83
    • 18144427879 scopus 로고    scopus 로고
    • The significance of skeletal-related events for the health-related quality of life of patients with metastatic prostate cancer
    • Weinfurt KP, Li Y, Castel LD et al. The significance of skeletal-related events for the health-related quality of life of patients with metastatic prostate cancer. Ann Oncol 2005; 16: 579-584.
    • (2005) Ann Oncol , vol.16 , pp. 579-584
    • Weinfurt, K.P.1    Li, Y.2    Castel, L.D.3
  • 84
    • 0030000537 scopus 로고    scopus 로고
    • Statistical issues in quality-of-life assessment
    • Chow SC, Ki FY. Statistical issues in quality-of-life assessment. J Biopharm Stat 1996; 6: 37-48.
    • (1996) J Biopharm Stat , vol.6 , pp. 37-48
    • Chow, S.C.1    Ki, F.Y.2
  • 85
    • 30344487620 scopus 로고    scopus 로고
    • Quality of life and symptom end points in palliative bone metastases trials
    • Chow E, Hoskin P, van der Linden Y et al. Quality of life and symptom end points in palliative bone metastases trials, Clin Oncol (R Coll Radiol) 2006; 18: 67-69.
    • (2006) Clin Oncol (R Coll Radiol) , vol.18 , pp. 67-69
    • Chow, E.1    Hoskin, P.2    van der Linden, Y.3
  • 86
    • 36549016075 scopus 로고    scopus 로고
    • Early phase in the development of a bone metastases quality of life module
    • Chow E, Harris K, Tharmalingam S et al, Early phase in the development of a bone metastases quality of life module. Clin Oncol (R Coll Radiol) 2007; 19: S26.
    • (2007) Clin Oncol (R Coll Radiol) , vol.19
    • Chow, E.1    Harris, K.2    Tharmalingam, S.3
  • 87
    • 40149091631 scopus 로고    scopus 로고
    • WHO's pain relief ladder
    • WHO's pain relief ladder. http://www.who.int/cancer/palliative/ painladder/en/.
  • 88
    • 0033040993 scopus 로고    scopus 로고
    • Bisphosphonates for metastatic bone pain
    • Body JJ. Bisphosphonates for metastatic bone pain. Support Care Cancer 1999; 7: 1-3.
    • (1999) Support Care Cancer , vol.7 , pp. 1-3
    • Body, J.J.1
  • 89
    • 33845655271 scopus 로고    scopus 로고
    • Combination ibandronate and radiotherapy for the treatment of bone metastases: Clinical evaluation and radiologic assessment
    • Vassiliou V, Kalogeropoulou C, Christopoulos C et al. Combination ibandronate and radiotherapy for the treatment of bone metastases: clinical evaluation and radiologic assessment. Int J Radiat Oncol Biol Phys 2007; 67: 264-272.
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , pp. 264-272
    • Vassiliou, V.1    Kalogeropoulou, C.2    Christopoulos, C.3
  • 90
    • 34249816181 scopus 로고    scopus 로고
    • A novel study investigating the therapeutic outcome of patients with lytic, mixed and sclerotic bone metastases treated with combined radiotherapy and ibandronate
    • Vassiliou V, Kalogeropoulou C, Giannopoulou E et al. A novel study investigating the therapeutic outcome of patients with lytic, mixed and sclerotic bone metastases treated with combined radiotherapy and ibandronate. Clin Exp Metastasis 2007; 24 (3): 169-178.
    • (2007) Clin Exp Metastasis , vol.24 , Issue.3 , pp. 169-178
    • Vassiliou, V.1    Kalogeropoulou, C.2    Giannopoulou, E.3
  • 91
    • 0034747656 scopus 로고    scopus 로고
    • The use of bisphosphonate for the palliative treatment of painful bone metastasis due to hormone refractory prostate cancer
    • Heidenreich A, Hofmann R, Engelmann UH. The use of bisphosphonate for the palliative treatment of painful bone metastasis due to hormone refractory prostate cancer. J Urol 2001; 165: 136-140.
    • (2001) J Urol , vol.165 , pp. 136-140
    • Heidenreich, A.1    Hofmann, R.2    Engelmann, U.H.3
  • 92
    • 4444327076 scopus 로고    scopus 로고
    • Efficacy and safety of ibandronate in the treatment of opioid-resistant bone pain associated with metastatic bone disease: A pilot study
    • Mancini I, Dumon JC, Body JJ. Efficacy and safety of ibandronate in the treatment of opioid-resistant bone pain associated with metastatic bone disease: A pilot study. J Clin Oncol 2004; 22: 3587-3592.
    • (2004) J Clin Oncol , vol.22 , pp. 3587-3592
    • Mancini, I.1    Dumon, J.C.2    Body, J.J.3
  • 93
    • 33847771427 scopus 로고    scopus 로고
    • Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis
    • Daubine F, Le Gall C, Gasser J et al. Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis. J Natl Cancer Inst 2007; 99: 322-330.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 322-330
    • Daubine, F.1    Le Gall, C.2    Gasser, J.3
  • 94
    • 13844297617 scopus 로고    scopus 로고
    • Ibandronate in metastatic bone disease: A review of preclinical data
    • Bauss F, Body JJ. Ibandronate in metastatic bone disease: A review of preclinical data. Anticancer Drugs 2005; 16: 107-118.
    • (2005) Anticancer Drugs , vol.16 , pp. 107-118
    • Bauss, F.1    Body, J.J.2
  • 95
    • 0035917560 scopus 로고    scopus 로고
    • The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: Evidence for synergy with paclitaxel
    • Jagdev SP, Coleman RE, Shipman CM et al. The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: Evidence for synergy with paclitaxel. Br J Cancer 2001; 84: 1126-1134.
    • (2001) Br J Cancer , vol.84 , pp. 1126-1134
    • Jagdev, S.P.1    Coleman, R.E.2    Shipman, C.M.3
  • 96
    • 40149095844 scopus 로고
    • Additive/synergistic anti-tumoral effects on prostate cancer cells in vitro following treatment with a combination of gemcitabine and zoledronic acid
    • Ullén A, Lennartsson L, Hjelm-Eriksson M et al. Additive/synergistic anti-tumoral effects on prostate cancer cells in vitro following treatment with a combination of gemcitabine and zoledronic acid. Proc Am Soc Clin Oncol 2003; 22: 432 (Abstr 1737).
    • (1737) Proc Am Soc Clin Oncol 2003; 22: 432 (Abstr
    • Ullén, A.1    Lennartsson, L.2    Hjelm-Eriksson, M.3
  • 97
    • 33646107396 scopus 로고    scopus 로고
    • Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro
    • Neville-Webbe HL, Evans CA, Coleman RE, Holen I. Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro, Tumour Biol 2006; 27: 92-103.
    • (2006) Tumour Biol , vol.27 , pp. 92-103
    • Neville-Webbe, H.L.1    Evans, C.A.2    Coleman, R.E.3    Holen, I.4
  • 98
    • 11144254409 scopus 로고    scopus 로고
    • Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells
    • Neville-Webbe HL, Rostami-Hodjegan A, Evans CA et al. Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells. Int J Cancer 2005; 113: 364-371.
    • (2005) Int J Cancer , vol.113 , pp. 364-371
    • Neville-Webbe, H.L.1    Rostami-Hodjegan, A.2    Evans, C.A.3
  • 99
    • 16544379650 scopus 로고    scopus 로고
    • Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/ metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/ paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid
    • Vogt U, Bielawski KP, Bosse U, Schlotter CM. Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/ metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/ paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid. Oncol Rep 2004; 12: 1109-1114.
    • (2004) Oncol Rep , vol.12 , pp. 1109-1114
    • Vogt, U.1    Bielawski, K.P.2    Bosse, U.3    Schlotter, C.M.4
  • 100
    • 33748959356 scopus 로고    scopus 로고
    • Sequence- and concentration-dependent effects of acute and long-term exposure to the bisphosphonate ibandronate in combination with single and multiple fractions of ionising radiation doses in human breast cancer cell lines
    • Journe F, Magne N, Chaboteaux C et al. Sequence- and concentration-dependent effects of acute and long-term exposure to the bisphosphonate ibandronate in combination with single and multiple fractions of ionising radiation doses in human breast cancer cell lines. Clin Exp Metastasis 2006; 23: 135-147.
    • (2006) Clin Exp Metastasis , vol.23 , pp. 135-147
    • Journe, F.1    Magne, N.2    Chaboteaux, C.3
  • 101
    • 40149108284 scopus 로고    scopus 로고
    • Samarium-153Sm-EDTMP and zoledronic acid present synergistic action and are able to control pain and significantly improve QoL in elderly patients with MM. (Results of a phase II trial and 19 months follow up)
    • Iuliano F, Molica S, Abruzzese E et al. Samarium-153Sm-EDTMP and zoledronic acid present synergistic action and are able to control pain and significantly improve QoL in elderly patients with MM. (Results of a phase II trial and 19 months follow up). J Clin Oncol (Meeting Abstracts) 2004; 22: 6737.
    • (2004) J Clin Oncol (Meeting Abstracts) , vol.22 , pp. 6737
    • Iuliano, F.1    Molica, S.2    Abruzzese, E.3
  • 102
    • 33845912677 scopus 로고    scopus 로고
    • Therapy Insight: The risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease
    • Dunstan C, Felsenberg D, Seibel MJ. Therapy Insight: The risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease. Nat Clin Pract Oncol 2006; 4: 42-55.
    • (2006) Nat Clin Pract Oncol , vol.4 , pp. 42-55
    • Dunstan, C.1    Felsenberg, D.2    Seibel, M.J.3
  • 103
    • 11244311877 scopus 로고    scopus 로고
    • The bisphosphonate acute phase response: Rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins
    • Hewitt RE, Lissina A, Green AE et al. The bisphosphonate acute phase response: Rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins. Clin Exp Immunol 2005; 139: 101-111.
    • (2005) Clin Exp Immunol , vol.139 , pp. 101-111
    • Hewitt, R.E.1    Lissina, A.2    Green, A.E.3
  • 104
    • 0023632357 scopus 로고
    • The acute-phase response after bisphosphonate administration
    • Adami S, Bhalla AK, Dorizzi R et al. The acute-phase response after bisphosphonate administration. Calcif Tissue Int 1987; 41: 326-331.
    • (1987) Calcif Tissue Int , vol.41 , pp. 326-331
    • Adami, S.1    Bhalla, A.K.2    Dorizzi, R.3
  • 105
    • 0142025453 scopus 로고    scopus 로고
    • Chang JT, Green L, Beitz J. Renal failure with the use of zoledronic acid. N Engl J Med 2003; 349: 1676-1679; discussion 1676-1679.
    • Chang JT, Green L, Beitz J. Renal failure with the use of zoledronic acid. N Engl J Med 2003; 349: 1676-1679; discussion 1676-1679.
  • 106
    • 0032758687 scopus 로고    scopus 로고
    • Comparative tolerability of drug therapies for hypercalcaemia of malignancy
    • Zojer N, Keck AV, Pecherstorfer M. Comparative tolerability of drug therapies for hypercalcaemia of malignancy. Drug Saf 1999; 21: 389-406.
    • (1999) Drug Saf , vol.21 , pp. 389-406
    • Zojer, N.1    Keck, A.V.2    Pecherstorfer, M.3
  • 107
    • 9144245854 scopus 로고    scopus 로고
    • Safety and pain palliation of zoledronic acid in patients with breast cancer, prostate cancer, or multiple myeloma who previously received bisphosphonate therapy
    • Vogel CL, Yanagihara RH, Wood AJ et al. Safety and pain palliation of zoledronic acid in patients with breast cancer, prostate cancer, or multiple myeloma who previously received bisphosphonate therapy. Oncologist 2004; 9: 687-695.
    • (2004) Oncologist , vol.9 , pp. 687-695
    • Vogel, C.L.1    Yanagihara, R.H.2    Wood, A.J.3
  • 108
    • 12144264025 scopus 로고    scopus 로고
    • Rapid administration of ibandronate does not affect renal functioning: Evidence from clinical studies in metastatic bone disease and hypercalcaemia of malignancy
    • Pecherstorfer M, Diel IJ. Rapid administration of ibandronate does not affect renal functioning: Evidence from clinical studies in metastatic bone disease and hypercalcaemia of malignancy. Support Care Cancer 2004; 12: 877-881.
    • (2004) Support Care Cancer , vol.12 , pp. 877-881
    • Pecherstorfer, M.1    Diel, I.J.2
  • 109
    • 33745049789 scopus 로고    scopus 로고
    • Long-term safety of intravenous ibandronic acid for up to 4 years in metastatic breast cancer: An open-label trial
    • Pecherstorfer M, Rivkin S, Body JJ et al. Long-term safety of intravenous ibandronic acid for up to 4 years in metastatic breast cancer: An open-label trial. Clin Drug Investig 2006; 26: 315-322.
    • (2006) Clin Drug Investig , vol.26 , pp. 315-322
    • Pecherstorfer, M.1    Rivkin, S.2    Body, J.J.3
  • 111
    • 33646836925 scopus 로고    scopus 로고
    • Narrative [corrected] review: Bisphosphonates and osteonecrosis of the jaws
    • Woo SB, Hellstein JW, Kalmar JR. Narrative [corrected] review: bisphosphonates and osteonecrosis of the jaws. Ann Intern Med 2006; 144: 753-761.
    • (2006) Ann Intern Med , vol.144 , pp. 753-761
    • Woo, S.B.1    Hellstein, J.W.2    Kalmar, J.R.3
  • 112
    • 33747879839 scopus 로고    scopus 로고
    • Bisphosphonates and osteonecrosis of the jaw: Cause and effect or a post hoc fallacy?
    • Van den Wyngaert T, Huizing MT, Vermorken JB. Bisphosphonates and osteonecrosis of the jaw: Cause and effect or a post hoc fallacy? Ann Oncol 2006; 17: 1197-1204.
    • (2006) Ann Oncol , vol.17 , pp. 1197-1204
    • Van den Wyngaert, T.1    Huizing, M.T.2    Vermorken, J.B.3
  • 113
    • 33748751877 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw: Background and guidelines for diagnosis, staging and management
    • Ruggiero SL, Fantasia J, Carlson E. Bisphosphonate-related osteonecrosis of the jaw: Background and guidelines for diagnosis, staging and management. Oral Sung Oral Med Oral Pathol Oral Radiol Endod 2006; 102: 433-441.
    • (2006) Oral Sung Oral Med Oral Pathol Oral Radiol Endod , vol.102 , pp. 433-441
    • Ruggiero, S.L.1    Fantasia, J.2    Carlson, E.3
  • 114
    • 27844555334 scopus 로고    scopus 로고
    • Does avascular necrosis of the jaws in cancer patients only occur following treatment with bisphosphonates?
    • Lenz JH, Steiner-Krammer B, Schmidt W et al. Does avascular necrosis of the jaws in cancer patients only occur following treatment with bisphosphonates? J Craniomaxillofac Surg 2005; 33: 395-403.
    • (2005) J Craniomaxillofac Surg , vol.33 , pp. 395-403
    • Lenz, J.H.1    Steiner-Krammer, B.2    Schmidt, W.3
  • 115
    • 34047235731 scopus 로고    scopus 로고
    • Oral bisphosphonate therapy and osteonecrosis of the jaw: What to tell the concerned patient
    • Koka S, Clarke BL, Amin S et al. Oral bisphosphonate therapy and osteonecrosis of the jaw: What to tell the concerned patient. Int J Prosthodont 2007; 20: 115-122.
    • (2007) Int J Prosthodont , vol.20 , pp. 115-122
    • Koka, S.1    Clarke, B.L.2    Amin, S.3
  • 116
    • 34147095972 scopus 로고    scopus 로고
    • Critical review: Updated recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients - May 2006, Crit Rev Oncol
    • Weitzmar R, Sauter N, Erksen EF. Critical review: Updated recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients - May 2006, Crit Rev Oncol Hematol 2007; 62: 148-152.
    • (2007) Hematol , vol.62 , pp. 148-152
    • Weitzmar, R.1    Sauter, N.2    Erksen, E.F.3
  • 117
    • 34347219133 scopus 로고    scopus 로고
    • Oral sodium clodronate induced osteonecrosis of the jaw in a patient with myeloma
    • Montazeri AH, Erskine JG, McQuaker IG. Oral sodium clodronate induced osteonecrosis of the jaw in a patient with myeloma. Eur J Haematol 2007; 79: 69-71.
    • (2007) Eur J Haematol , vol.79 , pp. 69-71
    • Montazeri, A.H.1    Erskine, J.G.2    McQuaker, I.G.3
  • 118
    • 33645229970 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in patients treated with bisphosphonates - histomorphologic analysis in comparison with infected osteoradionecrosis
    • Hansen T, Kunkel M, Weber A, James Kirkpatrick C. Osteonecrosis of the jaws in patients treated with bisphosphonates - histomorphologic analysis in comparison with infected osteoradionecrosis. J Oral Pathol Med 2006; 35: 155-160.
    • (2006) J Oral Pathol Med , vol.35 , pp. 155-160
    • Hansen, T.1    Kunkel, M.2    Weber, A.3    James Kirkpatrick, C.4
  • 119
    • 33751528987 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw - do bisphosphonates pose a risk?
    • Bilezikian JP. Osteonecrosis of the jaw - do bisphosphonates pose a risk? N Engl J Med 2006; 355: 2278-2281.
    • (2006) N Engl J Med , vol.355 , pp. 2278-2281
    • Bilezikian, J.P.1
  • 120
    • 33846085533 scopus 로고    scopus 로고
    • Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions: Of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis
    • Zheng Y, Zhou H, Brennan K et al. Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions: Of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis. Bone 2007; 40: 471-478.
    • (2007) Bone , vol.40 , pp. 471-478
    • Zheng, Y.1    Zhou, H.2    Brennan, K.3
  • 121
    • 0021248678 scopus 로고
    • Effects of chemotherapeutic agents on bone. I. Short-term methotrexate and doxorubicin (adriamycin) treatment in a rat model
    • Friedlaender GE, Tross RB, Doganis AC et al. Effects of chemotherapeutic agents on bone. I. Short-term methotrexate and doxorubicin (adriamycin) treatment in a rat model. J Bone Joint Sung Am 1984; 66: 602-607.
    • (1984) J Bone Joint Sung Am , vol.66 , pp. 602-607
    • Friedlaender, G.E.1    Tross, R.B.2    Doganis, A.C.3
  • 122
    • 0032512906 scopus 로고    scopus 로고
    • Bone loss induced by cancer treatment and its management
    • Delmas PD, Fontana A, Bone loss induced by cancer treatment and its management. Eur J Cancer 1998; 34: 260-262.
    • (1998) Eur J Cancer , vol.34 , pp. 260-262
    • Delmas, P.D.1    Fontana, A.2
  • 123
    • 0034037097 scopus 로고    scopus 로고
    • Osteoporosis due to cancer treatment: Pathogenesis and management
    • Pfeilschifter J, Diel IJ. Osteoporosis due to cancer treatment: pathogenesis and management. J Clin Oncol 2000; 18: 1570-1593.
    • (2000) J Clin Oncol , vol.18 , pp. 1570-1593
    • Pfeilschifter, J.1    Diel, I.J.2
  • 124
    • 29544433211 scopus 로고    scopus 로고
    • A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
    • Thurlimann B, Keshaviah A, Coates AS et al. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N Engl J Med 2005; 353: 2747-2757.
    • (2005) N Engl J Med , vol.353 , pp. 2747-2757
    • Thurlimann, B.1    Keshaviah, A.2    Coates, A.S.3
  • 125
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • Howell A, Cuzick J, Baum M et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 2005; 365: 60-62.
    • (2005) Lancet , vol.365 , pp. 60-62
    • Howell, A.1    Cuzick, J.2    Baum, M.3
  • 126
    • 33846545488 scopus 로고    scopus 로고
    • Skeletal effects of exemestane on bone-mineral density, bone biomarkers, and fracture incidence in postmenopausal women with early breast cancer participating in the intergroup Exemestane Study (IES): A randomsed controlled study
    • Coleman RE, Banks LM, Girgis SI et al. Skeletal effects of exemestane on bone-mineral density, bone biomarkers, and fracture incidence in postmenopausal women with early breast cancer participating in the intergroup Exemestane Study (IES): A randomsed controlled study. Lancet Oncol 2007; 8: 119-127.
    • (2007) Lancet Oncol , vol.8 , pp. 119-127
    • Coleman, R.E.1    Banks, L.M.2    Girgis, S.I.3
  • 127
    • 11844252588 scopus 로고    scopus 로고
    • Risk of fracture after androgen deprivation for prostate cancer
    • Shahinian VB, Kuo YF, Freeman JL, Goodwin JS. Risk of fracture after androgen deprivation for prostate cancer. N Engl J Med 2005; 352: 154-164.
    • (2005) N Engl J Med , vol.352 , pp. 154-164
    • Shahinian, V.B.1    Kuo, Y.F.2    Freeman, J.L.3    Goodwin, J.S.4
  • 128
    • 33746455931 scopus 로고    scopus 로고
    • Effect of an aromatase inhibitor on bmd and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial (18233230)
    • Eastell R, Hannon RA, Cuzick J et al. Effect of an aromatase inhibitor on bmd and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial (18233230). J Bone Miner Res 2006; 21: 1215-1223.
    • (2006) J Bone Miner Res , vol.21 , pp. 1215-1223
    • Eastell, R.1    Hannon, R.A.2    Cuzick, J.3
  • 130
    • 0035960116 scopus 로고    scopus 로고
    • Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer
    • Smith MR, McGovern FJ, Zietman AL et al. Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer. N Engl J Med 2001; 345: 948-955.
    • (2001) N Engl J Med , vol.345 , pp. 948-955
    • Smith, M.R.1    McGovern, F.J.2    Zietman, A.L.3
  • 131
    • 0032504985 scopus 로고    scopus 로고
    • Endogenous hormones and the risk of hip and vertebral fractures among older women. Study of Osteoporotic Fractures' Research Group
    • Cummings SR, Browner WS, Bauer D et al. Endogenous hormones and the risk of hip and vertebral fractures among older women. Study of Osteoporotic Fractures' Research Group. N Engl J Med 1998; 339: 733-738.
    • (1998) N Engl J Med , vol.339 , pp. 733-738
    • Cummings, S.R.1    Browner, W.S.2    Bauer, D.3
  • 132
    • 22144497431 scopus 로고    scopus 로고
    • Osteoporosis in breast and prostate cancer survivors
    • Hoff AO, Gagel RF. Osteoporosis in breast and prostate cancer survivors. Oncology (Williston Park) 2005; 19: 651-658.
    • (2005) Oncology (Williston Park) , vol.19 , pp. 651-658
    • Hoff, A.O.1    Gagel, R.F.2
  • 133
    • 0031045147 scopus 로고    scopus 로고
    • Clodronate improves bone mineral density in post-menopausal breast cancer patients treated with adjuvant antioestrogens
    • Saarto T, Blomqvist C, Valimaki M et al. Clodronate improves bone mineral density in post-menopausal breast cancer patients treated with adjuvant antioestrogens. Br J Cancer 1997; 75: 602-605.
    • (1997) Br J Cancer , vol.75 , pp. 602-605
    • Saarto, T.1    Blomqvist, C.2    Valimaki, M.3
  • 134
    • 0031057249 scopus 로고    scopus 로고
    • Bisphosphonate risedronate prevents bone loss in women with artificial menopause due to chemotherapy of breast cancer: A double-blind, placebo-controlled study
    • Delmas PD, Balena R, Confravreux E et al. Bisphosphonate risedronate prevents bone loss in women with artificial menopause due to chemotherapy of breast cancer: A double-blind, placebo-controlled study. J Clin Oncol 1997; 15: 955-962.
    • (1997) J Clin Oncol , vol.15 , pp. 955-962
    • Delmas, P.D.1    Balena, R.2    Confravreux, E.3
  • 135
    • 0032490125 scopus 로고    scopus 로고
    • Oral clodronate and reduction in loss of bone mineral density in women with operable primary breast cancer
    • Powles TJ, McCloskey E, Paterson AH et al. Oral clodronate and reduction in loss of bone mineral density in women with operable primary breast cancer. J Natl Cancer Inst 1998; 90: 704-708.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 704-708
    • Powles, T.J.1    McCloskey, E.2    Paterson, A.H.3
  • 136
    • 33947732766 scopus 로고    scopus 로고
    • Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: A randomized trial
    • Greenspan SL, Nelson JB, Trump DL, Resnick NM. Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: A randomized trial. Ann Intern Med 2007; 146: 416-424.
    • (2007) Ann Intern Med , vol.146 , pp. 416-424
    • Greenspan, S.L.1    Nelson, J.B.2    Trump, D.L.3    Resnick, N.M.4
  • 137
    • 33947539707 scopus 로고    scopus 로고
    • Zoledronic acid effectively prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: A report from the Austrian Breast and Colorectal Cancer Study Group
    • Gnant MF, Mlineritsch B, Luschin-Ebengreuth G et al. Zoledronic acid effectively prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: A report from the Austrian Breast and Colorectal Cancer Study Group. J Clin Oncol 2007; 25 (7): 820-828.
    • (2007) J Clin Oncol , vol.25 , Issue.7 , pp. 820-828
    • Gnant, M.F.1    Mlineritsch, B.2    Luschin-Ebengreuth, G.3
  • 138
    • 33947524592 scopus 로고    scopus 로고
    • Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer
    • Brufsky A, Harker WG, Beck JT et al. Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer. J Clin Oncol 2007; 25 (7): 829-836.
    • (2007) J Clin Oncol , vol.25 , Issue.7 , pp. 829-836
    • Brufsky, A.1    Harker, W.G.2    Beck, J.T.3
  • 139
    • 34250619592 scopus 로고    scopus 로고
    • An integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole
    • Brufsky A, Bundred N, Coleman R. An integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole. Breast Cancer Res Treat 2006; 100 (Suppl 1): S25.
    • (2006) Breast Cancer Res Treat , vol.100 , Issue.SUPPL. 1
    • Brufsky, A.1    Bundred, N.2    Coleman, R.3
  • 140
    • 34047237418 scopus 로고    scopus 로고
    • Randomized controlled trial of annual zoledronic acid to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer
    • Michaelson MD, Kaufman DS, Lee H et al. Randomized controlled trial of annual zoledronic acid to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer. J Clin Oncol 2007; 25: 1038-1042.
    • (2007) J Clin Oncol , vol.25 , pp. 1038-1042
    • Michaelson, M.D.1    Kaufman, D.S.2    Lee, H.3
  • 141
    • 0038075478 scopus 로고    scopus 로고
    • Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer
    • Smith MR, Eastham J, Gleason DM et al. Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer. J Urol 2003; 169: 2008-2012.
    • (2003) J Urol , vol.169 , pp. 2008-2012
    • Smith, M.R.1    Eastham, J.2    Gleason, D.M.3
  • 142
    • 33750705040 scopus 로고    scopus 로고
    • Oral clodronate maintains bone mass in women with primary breast cancer
    • Abstr 535
    • McCloskey E, Paterson AHG, Powles TJ. Oral clodronate maintains bone mass in women with primary breast cancer. J Clin Oncol 2005; 23 (Abstr 535).
    • (2005) J Clin Oncol , pp. 23
    • McCloskey, E.1    Paterson, A.H.G.2    Powles, T.J.3
  • 143
    • 33745008487 scopus 로고    scopus 로고
    • Effects of oral clodronate (BONEFOS (R)) therapy on bone turnover and skeletal metastases in women with primary breast cancer
    • Abstr 43
    • McCloskey E, Paterson AHG, Powles TJ. Effects of oral clodronate (BONEFOS (R)) therapy on bone turnover and skeletal metastases in women with primary breast cancer. Breast Cancer Res Treat 2005; 94 (Suppl 1): 5 (Abstr 43).
    • (2005) Breast Cancer Res Treat , vol.94 , Issue.SUPPL. 1 , pp. 5
    • McCloskey, E.1    Paterson, A.H.G.2    Powles, T.J.3
  • 144
    • 40149092750 scopus 로고    scopus 로고
    • Lester JE, Gutcher SA, Ellis SP et al. Effect of monthly oral ibandronate on anastrozole-induced bone loss during adjuvant treatment for breast cancer: One-year results from the ARIBON study. J Clin Oncol (Meeting Abstracts) 2007; 25: (Abstr 553).
    • Lester JE, Gutcher SA, Ellis SP et al. Effect of monthly oral ibandronate on anastrozole-induced bone loss during adjuvant treatment for breast cancer: One-year results from the ARIBON study. J Clin Oncol (Meeting Abstracts) 2007; 25: (Abstr 553).
  • 145
    • 40149106245 scopus 로고    scopus 로고
    • Recommendation for the prevention of Aromatase Inhibitor associated Bone Loss in women with Breast Cancer. Submitted Poster Presentation
    • Aapro M, Hadji P, Brufsky A et al. Recommendation for the prevention of Aromatase Inhibitor associated Bone Loss in women with Breast Cancer. Submitted Poster Presentation, ECCO 14, 2007.
    • (2007) ECCO , vol.14
    • Aapro, M.1    Hadji, P.2    Brufsky, A.3
  • 146
    • 0032491037 scopus 로고    scopus 로고
    • Reduction in new metastases in breast cancer with adjuvant clodronate treatment
    • Diel IJ, Solomayer EF, Costa SD et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med 1998; 339: 357-363.
    • (1998) N Engl J Med , vol.339 , pp. 357-363
    • Diel, I.J.1    Solomayer, E.F.2    Costa, S.D.3
  • 147
    • 9444254706 scopus 로고    scopus 로고
    • Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients
    • Saarto T, Vehmanen L, Virkkunen P, Blomqvist C. Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients. Acta Oncol 2004; 43: 650-656.
    • (2004) Acta Oncol , vol.43 , pp. 650-656
    • Saarto, T.1    Vehmanen, L.2    Virkkunen, P.3    Blomqvist, C.4
  • 148
    • 33744828376 scopus 로고    scopus 로고
    • Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]
    • Powles T, Paterson A, McCloskey E et al. Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]. Breast Cancer Res 2006; 8: R13.
    • (2006) Breast Cancer Res , vol.8
    • Powles, T.1    Paterson, A.2    McCloskey, E.3
  • 150
    • 5444270251 scopus 로고    scopus 로고
    • Adjuvant clodronate treatment improves the overall survival of primary breast cancer patients with micrometastases to bone marrow - a longtime follow-up
    • Jaschke A, Bastert G, Solomayer EF et al. Adjuvant clodronate treatment improves the overall survival of primary breast cancer patients with micrometastases to bone marrow - a longtime follow-up. J Clin Oncol (Meeting Abstracts) 2004; 22: 529.
    • (2004) J Clin Oncol (Meeting Abstracts) , vol.22 , pp. 529
    • Jaschke, A.1    Bastert, G.2    Solomayer, E.F.3
  • 151
    • 34250326616 scopus 로고    scopus 로고
    • Meta-analysis of clodronate and breast cancer survival
    • Ha TC, Li H. Meta-analysis of clodronate and breast cancer survival. Br J Cancer 2007; 96: 1796-1801.
    • (2007) Br J Cancer , vol.96 , pp. 1796-1801
    • Ha, T.C.1    Li, H.2
  • 152
    • 22344455489 scopus 로고    scopus 로고
    • Randomized, open label, prospective study on the effect of zoledronic acid on the prevention of bone metastases in patients with recurrent solid tumors that did not present with bone metastases at baseline
    • Mystakidou K, Katsouda E, Parpa E et al. Randomized, open label, prospective study on the effect of zoledronic acid on the prevention of bone metastases in patients with recurrent solid tumors that did not present with bone metastases at baseline. Med Oncol 2005; 22: 195-201.
    • (2005) Med Oncol , vol.22 , pp. 195-201
    • Mystakidou, K.1    Katsouda, E.2    Parpa, E.3
  • 153
    • 40149107233 scopus 로고    scopus 로고
    • Rack W, Janni A, Schoberth C et al. Effect of zoledronate on persisting isolated tumor cells (ITC) in the bone marrow (BM) of patients without recurrence of early breast cancer. Proc Am Soc Clin Oncol 2004; 23 (Suppl): 843 (Abstract 9515).
    • Rack W, Janni A, Schoberth C et al. Effect of zoledronate on persisting isolated tumor cells (ITC) in the bone marrow (BM) of patients without recurrence of early breast cancer. Proc Am Soc Clin Oncol 2004; 23 (Suppl): 843 (Abstract 9515).


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