Design driven HtL: The discovery and synthesis of new high efficacy β 2-agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 13, 2011, Pages 4027-4031

  Stocks, Michael J ^a   Alcaraz, Lilian ^a   Bailey, Andrew ^a   Bonnert, Roger ^a   Cadogan, Elaine ^a   Christie, Jadeen ^a   Connolly, Stephen ^a   Cook, Anthony ^a   Fisher, Adrian ^a   Flaherty, Alice ^a   Hill, Stephen ^a   Humphries, Alexander ^a   Ingall, Anthony ^a   Jordan, Stephen ^a   Lawson, Mandy ^a   Mullen, Alex ^a   Nicholls, David ^a   Paine, Stuart ^a   Pairaudeau, Garry ^a   St Gallay, Stephen ^a   Young, Alan ^a   more..

^a ASTRAZENECA   (United Kingdom)

Author keywords

2 Agonists; Adrenoreceptor agonist; Asthma; COPD; Inhaled; LABA

Indexed keywords

BENZYL ALCOHOL; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; FORMOTEROL; INDACATEROL; ISOPRENALINE; OLODATEROL; SALBUTAMOL; SALMETEROL; SIBENADET; TERBUTALINE;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; HYPOTHESIS; MOLECULAR MODEL;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ANIMALS; BRONCHI; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79958758200     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.135     Document Type: Article

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