Discovery of olodaterol, a novel inhaled β2-adrenoceptor agonist with a 24 h bronchodilatory efficacy

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 4, 2010, Pages 1410-1414

  Bouyssou, Thierry ^a   Hoenke, Christoph ^a   Rudolf, Klaus ^a   Lustenberger, Philipp ^a   Pestel, Sabine ^a   Sieger, Peter ^a   Lotz, Ralf ^a   Heine, Claudia ^a   Büttner, Frank H ^a   Schnapp, Andreas ^a   Konetzki, Ingo ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Adrenoceptor agonist; Asthma; Beta2; Bronchodilator; Bronchoprotection; COPD; LABA; Olodaterol

Indexed keywords

ACETYLCHOLINE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; OLODATEROL; UNCLASSIFIED DRUG;

ARTICLE; BRONCHODILATING ACTIVITY; BRONCHOSPASM; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG STRUCTURE; EXPERIMENTAL DOG; EXPERIMENTAL GUINEA PIG; NONHUMAN;

ADMINISTRATION, INHALATION; ANIMALS; BENZOXAZINES; BRONCHODILATOR AGENTS; CHO CELLS; CRICETINAE; CRICETULUS; DOGS; GUINEA PIGS; HUMANS; MALE; MOLECULAR STRUCTURE; RECEPTORS, ADRENERGIC, BETA-2; RECOMBINANT PROTEINS; STEREOISOMERISM; TREATMENT OUTCOME;

CANIS FAMILIARIS; CAVIA;

EID: 75449116988     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.087     Document Type: Article

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