Lyophilization monophase solution technique for preparation of amorphous flutamide dispersions

Drug Development and Industrial Pharmacy

Volumn 37, Issue 7, 2011, Pages 754-764

  Elgindy, Nazik ^a   Elkhodairy, Kadria ^a   Molokhia, Abdallah ^b   Elzoghby, Ahmed ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

^b Pharco Pharmaceutical Co   (Egypt)

Author keywords

amorphous dispersions; Lyophilization monophase solution; particle size; physical stability; surface area and porosity

Indexed keywords

FLUTAMIDE; MACROGOL 6000; POLOXAMER; POVIDONE; POVIDONE K 30; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED DRUG RELEASE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; DRUG SYNTHESIS; FREEZE DRYING; GAS CHROMATOGRAPHY; LYOPHILIZATION MONOPHASE SOLUTION TECHNIQUE; PARAMETER; PARTICLE SIZE; POROSITY; SURFACE AREA; TECHNIQUE; X RAY DIFFRACTION;

ANDROGEN ANTAGONISTS; ANTINEOPLASTIC AGENTS, HORMONAL; BIOLOGICAL AVAILABILITY; DRUG COMPOUNDING; DRUG STABILITY; FLUTAMIDE; FREEZE DRYING; HUMANS; MALE; PARTICLE SIZE; POLOXAMER; POLYETHYLENE GLYCOLS; POVIDONE; PROSTATIC NEOPLASMS; SOLUBILITY; SOLUTIONS;

EID: 79958738521     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2010.539232     Document Type: Article

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