Lyophilization monophase solution technique for improvement of the physicochemical properties of an anticancer drug, flutamide

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 74, Issue 2, 2010, Pages 397-405

  Elgindy, Nazik ^a   Elkhodairy, Kadria ^a   Molokhia, Abdallah ^b   Elzoghby, Ahmed ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

^b Pharco Pharmaceutical Co   (Egypt)

Author keywords

Cyclodextrins; Flutamide; Inclusion complexes; Lyophilization; Monophase solution

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ANTINEOPLASTIC AGENT; BETA CYCLODEXTRIN; FLUTAMIDE; TERT BUTYL ALCOHOL;

ARTICLE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SOLUTION; DRUG STABILITY; FREEZE DRYING; GAS CHROMATOGRAPHY; HUMIDITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; MELTING POINT; PARTICLE SIZE; PHYSICAL CHEMISTRY; POROSITY; REACTION TIME; SURFACE PROPERTY; X RAY DIFFRACTION;

ANTINEOPLASTIC AGENTS; BETA-CYCLODEXTRINS; CRYSTALLIZATION; DRUG COMPOUNDING; DRUG STABILITY; FLUTAMIDE; FREEZE DRYING; PARTICLE SIZE; PHARMACEUTICAL SOLUTIONS; SOLUBILITY; SURFACE PROPERTIES;

EID: 75449102533     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.11.011     Document Type: Article

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