Minocycline injection in the ventral posterolateral thalamus reverses microglial reactivity and thermal hyperalgesia secondary to sciatic neuropathy

Neuroscience Letters

Volumn 498, Issue 2, 2011, Pages 138-142

  LeBlanc, Brian W ^a,b   Zerah, Michele L ^a,b   Kadasi, Laith M ^a,b   Chai, Noori ^a,b   Saab, Carl Y ^a,b  

^a RHODE ISLAND HOSPITAL   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Microglia; P38; Pain; Thalamus; VPL

Indexed keywords

CD11 ANTIGEN; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE P38; OX42 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN; CHRONIC CONSTRICTION INJURY; CONTROLLED STUDY; DRUG ACTIVITY; HYPERALGESIA; IMMUNOREACTIVITY; INJECTION; MICROGLIA; NERVE INJURY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SCIATIC NEUROPATHY; THERMAL HYPERALGESIA; VENTRAL POSTEROLATERAL THALAMUS;

ANIMALS; ANTIBODIES, MONOCLONAL; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HOT TEMPERATURE; HYPERALGESIA; MALE; MICROGLIA; MINOCYCLINE; NERVE TISSUE PROTEINS; NEURALGIA; NEURONAL PLASTICITY; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; VENTRAL THALAMIC NUCLEI;

EID: 79958729017     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.04.077     Document Type: Article

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