Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors

Hearing Research

Volumn 134, Issue 1-2, 1999, Pages 1-8

  Derby, Michael L ^a   Sena Esteves, Miguel ^a   Breakefield, Xandra O ^a   Corey, David P ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c Hospital   (United States)

Author keywords

Cochlea; Gene therapy; Gene transfer; Herpes simplex virus; Inner ear; Vaccinia virus; Vital vector

Indexed keywords

BETA GALACTOSIDASE; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COCHLEA; CONTROLLED STUDY; CORTI ORGAN; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; GUINEA PIG; HEARING LOSS; HERPES SIMPLEX VIRUS 1; INNER EAR; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; VACCINIA VIRUS; VIRUS RECOMBINANT;

ANIMALS; BETA-GALACTOSIDASE; COCHLEA; EAR, INNER; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GUINEA PIGS; HERPESVIRUS 1, HUMAN; INFLAMMATION; TISSUE DISTRIBUTION; TRANSGENES; VACCINIA VIRUS;

EID: 0032867726     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5955(99)00045-3     Document Type: Article

References (52)

1. Boviatsis, E.J., Park, J.S., Sena-Esteves, M., Kramm, C.M., Chase, M., Efird, J.T., Wei, M.X., Breakefield, X.O., Chiocca, E.A., 1994a. Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene. Cancer Res. 54, 5745-5751.
2. Boviatsis, E.J., Scharf, J.M., Chase, M., Harrington, K., Breakefield, X.O., Chiocca, E.A., 1994b. Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase. Gene Ther. 1, 323-331.
3. Breakefield, X.O., Jacobs, A. and Wang, S. (1997) Genetic engineering for CNS regeneration. In: Tuszynski, M. (Ed.), CNS Regeneration: Basic Science and Clinical Applications, Vol 4. Academic Press, New York, pp. 1281-1283.
4. Brubaker, J.O., Thompson, C.M., Morrison, L.A., Knipe, D.M., Siber, G.R., Finberg, G.R.W., 1996. Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus. J. Immunol. 157, 1598-1604.
5. Buller, R.M.L., Smith, G.L., Cremer, K., Notkins, A.L., Moss, B., 1985. Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative phenotype. Nature 317, 813-815.
6. Chakrabarti, S., Sisler, J.R., Moss, B., 1997. A compact, synthetic, vaccinia virus early/late promoter for protein expression. Biotechniques 23, 1094-1097.
7. Cohen, N.L., Waltzman, S.B., Fisher, S.G. and Department of Veterans Affairs Cochlear Implant Study Group (1993) A prospective, randomized study of cochlear implants. N. Engl. J. Med. 328, 233-237.
8. Darmstadt, G.L., Keithley, E.M., Harris, J.P., 1990. Effects of cyclophosphamide on the pathogenesis of cytomegalovirus-induced labyrinthitis. Ann. Otol. Rhinol. Laryngol. 99, 960-968.
9. Darrow, D.H., Keithley, E.M., Harris, J.P., 1992. Effects of bacterial endotoxin applied to the guinea pig cochlea. Laryngoscope 102, 683-688.
10. Dazert, S., Battaglia, A., Ryan, A.F., 1997. Transfection of neonatal rat cochlear cells in vitro with an adenovirus vector. Int. J. Dev. Neurosci. 15, 595-600.
11. Derby, M.L., Sena-Esteves, M., Breakefield, X.O., Corey, D.P., 1995. Gene delivery to the mammalian and amphibian inner ears using viral vectors. Mol. Biol. Hear. Deafness Abstr. 152,
12. Earl, P.L. and Moss, B. (1991) Generation of recombinant vaccinia viruses. In: Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A. and Struhl, K. (Eds.), Current Protocols in Molecular Biology. Greene Publishing Associates and Wiley Interscience, New York, pp. 16.17.1-16.17.16.
13. Ernfors, P., Van De Water, T., Loring, J., Jaenisch, R., 1995. Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron 14, 1153-1164.
14. Fraefel, C., Song, S., Lim, F., Lang, P., Yu, L., Wang, Y., Wild, P., Geller, A.I., 1996. Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells. J. Virol. 70, 7190-7197.
15. Friedmann, T., 1994. Gene therapy for neurological disorders. Trends Genet. 10, 210-214.
16. Geschwind, M.D., Hartnick, C.J., Liu, W., Amat, J., Van De Water, T.R., Federoff, H.J., 1996. Defective HSV-1 vector expressing BDNF in auditory ganglia elicits neurite outgrowth: Model for treatment of neuron loss following cochlear degeneration. Hum. Gene Ther. 7, 173-182.
17. Glorioso, J.C., DeLuca, N.A., Fink, D.J., 1995. Development and application of herpes simplex virus vectors for human gene therapy. Annu. Rev. Microbiol. 49, 675-710.
18. Goldstein, D.J., Weller, S.K., 1988. Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: Isolation and characterization of an ICP6 lacZ insertion mutant. J. Virol. 62, 196-205.
19. Hartshorn, D.O., Miller, J.M., Altschuler, R.A., 1991. Protective effect of electrical stimulation in the deafened guinea pig cochlea. Otolaryngol. Head Neck Surg. 104, 311-319.
20. Holt, J.R., Johns, D.C., Wang, S., Chen, Z-Y., Dunn, R.J., Marban, E., Corey, D.P., 1999. Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors. J. Neurophysiol. 81, 1881-1888.
21. Keithley, E.M., Woolf, N.K., Harris, J.P., 1989. Development of morphological and physiological changes in the cochlea induced by cytomegalovirus. Laryngoscope 99, 409-414.
22. Kelley, M.W., 1997. Cellular commitment and differentiation in the cochlea: Potential advances using gene transfer. Audiol. Neurootol. 2, 50-60.
23. Kikuchi, T., Kimura, R.S., Paul, D.L., Adams, J.C., 1995. Gap junctions in the rat cochlea: Immunohistochemical and ultrastructural analysis. Anat. Embryol. 191, 101-118.
24. Koburg, E., 1961. Autoradiographische Untersuchunger zum Nucleisauerstoffwechsel der Gewebe der Cochlea. Arch. Ohr. Nas. Kehlkd.-Heilkd. 178, 150-157.
25. Lalwani, A.K., Walsh, B.J., Reilly, P.G., Muzyczka, N., Mhatre, A.N., 1996. Development of in vivo gene therapy for hearing disorders : introduction of adeno-associated virus into the cochlea of the guinea pig. Gene Ther. 3, 588-592.
26. Lalwani, A.K., Walsh, B.J., Carvalho, G.J., Muzyczka, N., Mhatre, A.N., 1998a. Expression of adeno-associated virus integrated transgene within the mammalian vestibular organs. Am. J. Otol. 19, 390-395.
27. Lalwani, A., Walsh, B., Reilly, P., Carvalho, G., Zolotukhin, S., Muzyczka, N., Mhatre, A., 1998b. Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus. Gene Ther. 5, 277-281.
28. Low, W., Baird, A., Ryan, A.F., 1995. Protection of cochlear hair cells from aminoglycoside injury by basic fibroblast growth factor (FGF-2). Assoc. Res. Otolaryngol. Abstr. 18, 797.
29. Mackett, M., Smith, G.L. and Moss, B. (1985) The construction and characterization of vaccinia virus recombinants expressing foreign genes. In: Glover, D.M. (Ed.), DNA Cloning: A Practical Approach. IRL Press, Oxford, England, pp. 191-211.
30. Mineta, T., Rabkin, S.D., Martuza, R.L., 1994. Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant. Cancer Res. 54, 3963-3966.
31. Pettit, D., Perlman, S., Malinow, R., 1994. Increasing CaMKII activity in postsynaptic hippocampal slice neurons potentiates transmission and prevents further LTP. Science 266, 1881-1885.
32. Pettit, D.L., Koothan, T., Liao, D., Malinow, R., 1995. Vaccinia virus transfection of hippocampal slice neurons. Neuron 14, 685-688.
33. Pirvola, U., Ylikoski, J., Palgi, J., Lehtonen, E., Arumae, U., Saarma, M., 1992. Brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the peripheral target fields of developing inner ear ganglia. Proc. Natl. Acad. Sci. USA 89, 9915-9919.
34. Raphael, Y., Frisancho, J.C., Roessler, B.J., 1996. Adenoviral-mediated gene transfer into guinea pig cochlear cells in vivo. Neurosci. Lett. 207, 137-141.
35. Roberson, D.W., Rubel, E.W., 1994. Cell division in the gerbil cochlea after acoustic trauma. Am. J. Otol. 15, 28-34.
36. Ruben, R.J., 1967. Development of the inner ear of the mouse: A radioautographic study of terminal mitoses. Acta Otolaryngol. 220 ((Suppl.)), 4-44.
37. Samaniego, L.A., Neiderhiser, L., DeLuca, N.A., 1998. Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J. Virol. 72, 3307-3320.
38. Smith, F., Jacoby, D., Breakefield, X.O., 1995. Virus vectors for gene delivery to the nervous system. Rest. Neurol. Neurosci. 8, 21-34.
39. Staecker, H., Gabaizadeh, R., Federoff, H., Van De Water, T.R., 1998. Brain-derived neurotrophic factor gene therapy prevents spiral ganglion degeneration after hair cell loss. Otolaryngol. Head Neck Surg. 119, 7-13.
40. Staecker, H., Liu, W., Hartnick, C., Lefebvre, P., Malgrange, B., Moonen, G., Van De Water, T., 1995b. NT-3 combined with CNTF promotes survival of neurons in modiolus-spiral ganglion explants. Neuroreport 6, 1533-1537.
41. Stearns, G.S., Keithley, E.M., Harris, J.P., 1993. Development of high endothelial venule-like characteristics in the spiral modiolar vein induced by viral labyrinthitis. Laryngoscope 103, 890-898.
42. Steel, K.P., Brown, S.D., 1996. Genetics of deafness. Curr. Opin. Neurobiol. 6, 520-525.
43. Suhr, S.T., Gage, F.H., 1993. Gene therapy for neurologic disease. Arch. Neurol. 50, 1252-1268.
44. Suzuki, M., Harris, J.P., 1995. Expression of intracellular adhesion molecule-1 during inner ear inflammation. Ann. Otol. Rhinol. Laryngol. 104, 69-75.
45. Weiss, M.A., Frisancho, J.C., Roessler, B.J., Raphael, Y., 1997. Viral-mediated gene transfer in the cochlea. Int. J. Dev. Neurosci. 15, 577-585.
46. Weisz, O.A. and Machamer, C.E. (1994) Use of recombinant vaccinia virus vectors for cell biology. In: Roth, M.G. (Ed.), Methods in Cell Biology. Academic Press, Inc., San Diego, CA, pp. 137-159.
47. Wheeler, E.F., Bothwell, M., Schecterson, L.C., Von Bartheld, C.S., 1994. Expression of BDNF and NT-3 mRNA in hair cells of the organ of Corti: Quantitative analysis in developing rats. Hear. Res. 73, 46-56.
48. Wood, M.J., Charlton, H.M., Wood, K.J., Kajiwera, K., Byrnes, A.P., 1996. Immune responses to adenovirus vectors in the nervous system. Trends Neurosci. 19, 497-501.
49. Wu, G-Y., Zou, D-J., Koothan, T., Cline, H.T., 1995. Infection of frog neurons with vaccinia virus permits in vivo expression of foreign proteins. Neuron 14, 681-684.
50. Yeo, S.W., Gottschlich, S., Harris, J.P., Keithley, E.M., 1995. Antigen diffusion from the perilymphatic space of the cochlea. Laryngoscope 105, 623-628.
51. Ylikoski, J., Pirvola, U., Moshnyakov, M., Palgi, J., Arumae, U., Saarma, M., 1993. Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear. Hear. Res. 65, 69-78.
52. Zheng, J.L., Stewart, R.R., Gao, W-Q., 1995. Neurotrophin-4/5 enhances survival of cultured spiral ganglion neurons and protects them from cisplatin neurotoxicity. J. Neurosci. 15, 5079-5087.