Loss of a single Hic1 allele accelerates polyp formation in Apc Δ716 mice

Oncogene

Volumn 30, Issue 23, 2011, Pages 2659-2669

  Mohammad, H P ^a   Zhang, W ^a   Prevas, H S ^a   Leadem, B R ^a   Zhang, M ^a   Herman, J G ^a   Hooker, C M ^a   Watkins, D N ^b   Karim, B ^c   Huso, D L ^c   Baylin, S B ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b MONASH UNIVERSITY   (Australia)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

colon cancer; DNA hypermethylation; Hic1; Min; Polyp

Indexed keywords

APC PROTEIN; BETA CATENIN; SIRTUIN 1; TRANSCRIPTION FACTOR SOX9;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; EPIGENETICS; FEMALE; GASTROINTESTINAL POLYPOSIS; GENE; GENE EXPRESSION; GENE LOSS; HETEROZYGOTE; HYPERMETHYLATED IN CANCER 1 GENE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CELLS, CULTURED; CPG ISLANDS; DNA METHYLATION; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HETEROZYGOTE; HUMANS; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; INTESTINE, SMALL; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIRTUIN 1; SOX9 TRANSCRIPTION FACTOR;

MUS;

EID: 79958278998     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.633     Document Type: Article

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